المؤلفون: Brett A. Beaupre (10871400), Dariush C. Forouzesh (10871403), Arseniy Butrin (8506680), Dali Liu (752104), Graham R. Moran (1473295)

مصطلحات موضوعية: Biochemistry, Cell Biology, Immunology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, electron, C 671S variant, X-ray crystal structure analysis, binding difference spectrum, C 671 residue, C 671 variants, charge transfer absorption, NADPH, reductive activation reaction, DPD, Porcine Dihydropyrimidine Dehydrogenase, FAD, Fe 4 S 4 centers, FMN, phase results

Relation: https://figshare.com/articles/journal_contribution/Perturbing_the_Movement_of_Hydrogens_to_Delineate_and_Assign_Events_in_the_Reductive_Activation_and_Turnover_of_Porcine_Dihydropyrimidine_Dehydrogenase/14673105

الاتاحة: https://doi.org/10.1021/acs.biochem.1c00243.s001

المؤلفون: Dariush C. Forouzesh (10354164), Brett A. Beaupre (1682800), Arseniy Butrin (8506680), Zdzislaw Wawrzak (1330530), Dali Liu (752104), Graham R. Moran (1473295)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Molecular Biology, Immunology, Cancer, Environmental Sciences not elsewhere classified, k inact value, nonreductive NADPH analogues, 5 EU, pyrimidine binding site, electrons 56 Å, 5-, DPD activity levels, 5 FU, Porcine Dihydropyrimidine Dehydrogenase, nicotinamide adenine dinucleotide p., 5 EU ethynyl group, proton-coupled electron transfer me., covalently inactivates DPD

Relation: https://figshare.com/articles/journal_contribution/The_Interaction_of_Porcine_Dihydropyrimidine_Dehydrogenase_with_the_Chemotherapy_Sensitizer_5_Ethynyluracil/14269362

الاتاحة: https://doi.org/10.1021/acs.biochem.1c00096.s001

المؤلفون: Brett A. Beaupre, Dariush C. Forouzesh, Arseniy Butrin, Dali Liu, Graham R. Moran

مصطلحات موضوعية: Biochemistry, Cell Biology, Immunology, Computational Biology, Space Science, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, electron, C 671S variant, X-ray crystal structure analysis, binding difference spectrum, C 671 residue, C 671 variants, charge transfer absorption, NADPH, reductive activation reaction, DPD, Porcine Dihydropyrimidine Dehydrogenase, FAD, Fe 4 S 4 centers, FMN, phase results, geo, socio

Relation: https://doi.org/10.1021/acs.biochem.1c00243.s001

الاتاحة: https://doi.org/10.1021/acs.biochem.1c00243.s001