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1Academic Journal
المؤلفون: Delong Wang, Chunxia Yuan, Yunpeng Li, Shuhong Bai, Juntao Feng, Yong Wang, Yali Fang, Zhijia Zhang
مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Pharmacology, Biotechnology, Chemical Sciences not elsewhere classified, toxicological observations demonstrated, striking preventive effect, shorter alkyl chain, reactive oxygen species, pyrone core motif, previously identified 3, moderate promiscuous inhibitor, minimum inhibitory concentration, carbon atom number, alkyl side chain, controlling rape diseases, bioassay results revealed, potent antifungal pogostone, potent antifungal analogue, ml ), respectively, mitochondrial complexes ii, 34 b, 21 b, mitochondrial membrane potential, 50 sub, xcc <, vitro <, results highlight
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2Academic Journal
المؤلفون: A. Ghanbari, C. Jalili, I. Rashidi, H. Toranj, F. Raissi, F. Mazini, N. Akhshi
المصدر: World Cancer Research Journal, Vol 10 (2023)
مصطلحات موضوعية: melanoma, dacarbazine, pogostone, apoptosis, autophagy, drug resistance, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
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3Academic Journal
المؤلفون: Yu, James, Landberg, Jenny, Shavarebi, Farbod, Bilanchone, Virginia, Okerlund, Adam, Wanninayake, Umayangani, Zhao, Le, Kraus, George, Sandmeyer, Suzanne
المصدر: Biotechnology and Bioengineering. 115(9)
مصطلحات موضوعية: Biological Sciences, Industrial Biotechnology, Asteraceae, Culture Media, Metabolic Engineering, Metabolic Networks and Pathways, Plant Proteins, Pyrones, Recombinant Proteins, Yarrowia, lipids, pogostone, polyketide, triacetic acid lactone, Yarrowia lipolytica, Biotechnology
وصف الملف: application/pdf
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4Academic Journal
المؤلفون: Mansour Homayoun, Nayereh Sajedi, Mitra Soleimani
المصدر: Research in Pharmaceutical Sciences, Vol 17, Iss 2, Pp 164-175 (2022)
مصطلحات موضوعية: apoptosis, cell cycle, dact1, ovarian cancer, pogostone, pten., Pharmacy and materia medica, RS1-441
وصف الملف: electronic resource
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5Academic Journal
المؤلفون: D. Rezazadeh, S. Asadi, H. Nemati, C. Jalili
المصدر: World Cancer Research Journal, Vol 9 (2022)
مصطلحات موضوعية: pogostone, liver cancer cell, viability, membrane integrity, apoptosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
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6Academic Journal
المؤلفون: Shengnan Xie, Li Li, Baihe Zhan, Xue Shen, Xuming Deng, Wenxi Tan, Tianqi Fang
المصدر: Molecules; Volume 27; Issue 9; Pages: 2819
مصطلحات موضوعية: MCR-1, pogostone, colistin, Enterobacteriaceae
جغرافية الموضوع: agris
وصف الملف: application/pdf
Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules27092819
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7Academic Journal
المؤلفون: Waikit Leong, Guoxin Huang, Imran Khan, Wenrui Xia, Yucui Li, Yuhong Liu, Xiaoang Li, Ruixuan Han, Ziren Su, W. L. Wendy Hsiao
المصدر: Frontiers in Pharmacology, Vol 10 (2019)
مصطلحات موضوعية: patchouli essential oil, patchouli alcohol, pogostone, β-patchoulene, gut microbiota, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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8
المؤلفون: Mitra Soleimani, Mansour Homayoun, Nayereh Sajedi
المصدر: Research in Pharmaceutical Sciences, Vol 17, Iss 2, Pp 164-175 (2022)
مصطلحات موضوعية: RS1-441, Pharmacy and materia medica, apoptosis, cell cycle, dact1, ovarian cancer, pogostone, pten, General Pharmacology, Toxicology and Pharmaceutics
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9Academic Journal
المؤلفون: Reiza, Yaumil
المصدر: Cermin Dunia Kedokteran; Vol. 45 No. 11 (2018): Neurologi; 807 - 813 ; 2503-2720 ; 0125-913X ; 10.55175/cdk.v45i11
مصطلحات موضوعية: Antibakterial, minyak nilam, nilam aceh (Pogostemon cablin Benth.), pogostone
وصف الملف: application/pdf
Relation: https://cdkjournal.com/index.php/cdk/article/view/691/619; https://cdkjournal.com/index.php/cdk/article/view/691
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10Academic Journal
المؤلفون: Jiyan Su, Cailan Li, Xiuting Yu, Guanghua Yang, Jianhua Deng, Ziren Su, Huifang Zeng, Jiannan Chen, Xiaojun Zhang, Xiaoping Lai
المصدر: Frontiers in Pharmacology, Vol 8 (2017)
مصطلحات موضوعية: pogostone, TNBS, experimental colitis, anti-inflammation, T helper cell, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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11Academic Journal
المؤلفون: Wang, Chu, Wang, Ying, Chen, Jing, Liu, Lang, Yang, Mingxia, Li, Zhengguo, Wang, Chengyuan, Pichersky, Eran, Xu, Haiyang
مصطلحات موضوعية: 4-methylvaleric acid, branched-chain fatty acid, Pogostemon cablin, pogostone, α-ketoacid elongation pathway, 2-isobutylmalate, 2-isobutylmalate synthase, 2-isopropylmalate synthase, Natural Resources and Environment, Science
وصف الملف: application/pdf
Relation: Wang, Chu; Wang, Ying; Chen, Jing; Liu, Lang; Yang, Mingxia; Li, Zhengguo; Wang, Chengyuan; Pichersky, Eran; Xu, Haiyang (2022). "Synthesis of 4-methylvaleric acid, a precursor of pogostone, involves a 2-isobutylmalate synthase related to 2-isopropylmalate synthase of leucine biosynthesis." New Phytologist (3): 1129-1145.; https://hdl.handle.net/2027.42/172976; New Phytologist; Zheng W, Zhou XG, Wuyun QQG, Pearce R, Li Y, Zhang Y. 2020. FU pred: detecting protein domains through deep-learning-based contact map prediction. Bioinformatics 36: 3749 – 3757.; Koon N, Squire CJ, Baker EN. 2004. Crystal structure of LeuA from Mycobacterium tuberculosis, a key enzyme in leucine biosynthesis. Proceedings of the National Academy of Sciences, USA 101: 8295 – 8300.; de Kraker JW, Gershenzon J. 2011. From amino acid to glucosinolate biosynthesis: protein sequence changes in the evolution of methylthioalkylmalate synthase in Arabidopsis. Plant Cell 23: 38 – 53.; de Kraker JW, Luck K, Textor S, Tokuhisa JG, Gershenzon J. 2007. Two Arabidopsis genes ( IPMS1 and IPMS2 ) encode isopropylmalate synthase, the branchpoint step in the biosynthesis of leucine. Plant Physiology 143: 970 – 986.; Kroumova AB, Wagner GJ. 2003. Different elongation pathways in the biosynthesis of acyl groups of trichome exudate sugar esters from various solanaceous plants. Planta 216: 1013 – 1021.; Kumar R, Lee SG, Augustine R, Reichelt M, Vassao DG, Palavalli MH, Allen A, Gershenzon J, Jez JM, Bisht NC. 2019. Molecular basis of the evolution of methylthioalkylmalate synthase and the diversity of methionine-derived glucosinolates. Plant Cell 31: 1633 – 1647.; Kumar S, Stecher G, Li M, Knyaz C, Tamura K. 2018. M ega X: molecular evolutionary genetics analysis across computing platforms. Molecular Biology and Evolution 35: 1547 – 1549.; Zhou XG, Hu J, Zhang CX, Zhang GJ, Zhang Y. 2019. Assembling multidomain protein structures through analogous global structural alignments. Proceedings of the National Academy of Sciences, USA 116: 15930 – 15938.; Li CW, Wu XL, Zhao XN, Su ZQ, Chen HM, Wang XF, Zhang XJ, Zeng HF, Chen JN, Li YC et al. 2013. Anti-inflammatory property of the ethanol extract of the root and rhizome of Pogostemon cablin (Blanco) benth. Scientific World Journal 2013: 434151.; Li W, Zhou F, Pichersky E. 2018. Jasmone hydroxylase, a key enzyme in the synthesis of the alcohol moiety of pyrethrin insecticides. Plant Physiology 177: 1498 – 1509.; Li Y-C, Liang H-C, Chen H-M, Tan L-R, Yi Y-Y, Qin Z, Zhang W-M, Wu D-W, Li C-W, Lin R-F et al. 2012. Anti- Candida albicans activity and pharmacokinetics of pogostone isolated from Pogostemonis herba. Phytomedicine 20: 77 – 83.; Li Y-C, Xian Y-F, Su Z-R, Ip S-P, Xie J-H, Liao J-B, Wu D-W, Li C-W, Chen J-N, Lin Z-X et al. 2014. Pogostone suppresses proinflammatory mediator production and protects against endotoxic shock in mice. Journal of Ethnopharmacology 157: 212 – 221.; Li-Beisson Y, Shorrosh B, Beisson F, Andersson MX, Arondel V, Bates PD, Baud S, Bird D, DeBono A, Durrett TP et al. 2013. Acyl-lipid metabolism. The Arabidopsis Book 11: e0161.; Lousa CD, van Roermund CWT, Postis VLG, Dietrich D, Kerr ID, Wanders RJA, Baldwin SA, Baker A, Theodoulou FL. 2013. Intrinsic acyl-CoA thioesterase activity of a peroxisomal ATP binding cassette transporter is required for transport and metabolism of fatty acids. Proceedings of the National Academy of Sciences, USA 110: 1279 – 1284.; Luchesi LA, Paulus D, Busso C, Frata MT, Oliveira JB. 2020. Chemical composition, antifungal and antioxidant activity of essential oils from Baccharis dracunculifolia and Pogostemon cablin against Fusarium graminearum. Natural Product Research 34: 1 – 4.; Melendez-Hevia E, Waddell TG, Cascante M. 1996. The puzzle of the Krebs citric acid cycle: assembling the pieces of chemically feasible reactions, and opportunism in the design of metabolic pathways during evolution. Journal of Molecular Evolution 43: 293 – 303.; Ning J, Moghe GD, Leong B, Kim J, Ofner I, Wang Z, Adams C, Jones AD, Zamir D, Last RL. 2015. A feedback-insensitive isopropylmalate synthase affects acylsugar composition in cultivated and wild tomato. Plant Physiology 169: 1821 – 1835.; Ohlrogge J, Browse J. 1995. Lipid biosynthesis. Plant Cell 7: 957 – 970.; Peng F, Wan F, Xiong L, Peng C, Dai M, Chen JP. 2014. In vitro and in vivo antibacterial activity of Pogostone. Chinese Medical Journal 127: 4001 – 4005.; de Quiros HC, Magrath R, McCallum D, Kroymann J, Scnabelrauch D, Mitchell-Olds T, Mithen R. 2000. alpha-keto acid elongation and glucosinolate biosynthesis in Arabidopsis thaliana. Theoretical and Applied Genetics 101: 429 – 437.; Slocombe SP, Schauvinhold I, McQuinn RP, Besser K, Welsby NA, Harper A, Aziz N, Li Y, Larson TR, Giovannoni J et al. 2008. Transcriptomic and reverse genetic analyses of branched-chain fatty acid and acyl sugar production in Solanum pennellii and Nicotiana benthamiana. Plant Physiology 148: 1830 – 1846.; Stout JM, Boubakir Z, Ambrose SJ, Purves RW, Page JE. 2012. The hexanoyl-CoA precursor for cannabinoid biosynthesis is formed by an acyl-activating enzyme in Cannabis sativa trichomes. The Plant Journal 71: 353 – 365.; Sugimoto N, Engelgau P, Jones AD, Song J, Beaudry R. 2021. Citramalate synthase yields a biosynthetic pathway for isoleucine and straight- and branched-chain ester formation in ripening apple fruit. Proceedings of the National Academy of Sciences, USA 118: e2009988118.; Wang X-F, Huang Y-F, Wang L, Xu L-Q, Yu X-T, Liu Y-H, Li C-L, Zhan J-X, Su Z-R, Chen J-N et al. 2016. Photo-protective activity of pogostone against UV-induced skin premature aging in mice. Experimental Gerontology 77: 76 – 86.; Xing A, Last RL. 2017. A regulatory hierarchy of the Arabidopsis branched-chain amino acid metabolic network. Plant Cell 29: 1480 – 1499.; Xu H, Li W, Schilmiller AL, van Eekelen H, de Vos RCH, Jongsma MA, Pichersky E. 2019. Pyrethric acid of natural pyrethrin insecticide: complete pathway elucidation and reconstitution in Nicotiana benthamiana. New Phytologist 223: 751 – 765.; Xu H, Moghe GD, Wiegert-Rininger K, Schilmiller AL, Barry CS, Last RL, Pichersky E. 2018. Coexpression analysis identifies two oxidoreductases involved in the biosynthesis of the monoterpene acid moiety of natural pyrethrin insecticides in Tanacetum cinerariifolium. Plant Physiology 176: 524 – 537.; Xu H, Zhang F, Liu B, Huhman DV, Sumner LW, Dixon RA, Wang G. 2013. Characterization of the formation of branched short-chain fatty acid:coAs for bitter acid biosynthesis in hop glandular trichomes. Molecular Plant 6: 1301 – 1317.; Yang T, Stoopen G, Yalpani N, Vervoort J, de Vos R, Voster A, Verstappen FWA, Bouwmeester HJ, Jongsma MA. 2011. Metabolic engineering of geranic acid in maize to achieve fungal resistance is compromised by novel glycosylation patterns. Metabolic Engineering 13: 414 – 425.; Ye Q, Ling Q, Shen J, Shi L, Chen J, Yang T, Hou Z, Zhao J, Zhou H. 2021. Protective effect of pogostone on murine norovirus infected-RAW264.7 macrophages through inhibition of NF-κB/NLRP3-dependent pyroptosis. Journal of Ethnopharmacology 278: 114250.; Yoo SD, Cho YH, Sheen J. 2007. Arabidopsis mesophyll protoplasts: a versatile cell system for transient gene expression analysis. Nature Protocols 2: 1565 – 1572.; Binder S. 2010. Branched-chain amino acid metabolism in Arabidopsis thaliana. The Arabidopsis Book 8: e0137.; Binder S, Knill T, Schuster J. 2007. Branched-chain amino acid metabolism in higher plants. Physiologia Plantarum 129: 68 – 78.; Cao ZX, Yang YT, Yu S, Li YZ, Wang WW, Huang J, Xie XF, Xiong L, Lei S, Peng C. 2017. Pogostone induces autophagy and apoptosis involving PI3K/Akt/mTOR axis in human colorectal carcinoma HCT116 cells. Journal of Ethnopharmacology 202: 20 – 27.; de Carvalho LP, Argyrou A, Blanchard JS. 2005. Slow-onset feedback inhibition: inhibition of Mycobacterium tuberculosis alpha-isopropylmalate synthase by L-leucine. Journal of the American Chemical Society 127: 10004 – 10005.; Chen H, Liao H, Liu Y, Zheng Y, Wu X, Su Z, Zhang X, Lai Z, Lai X, Lin Z-X et al. 2015. Protective effects of pogostone from Pogostemonis herba against ethanol-induced gastric ulcer in rats. Fitoterapia 100: 110 – 117.; Chen J, Liu L, Wang Y, Li Z, Wang G, Kraus GA, Pichersky E, Xu H. 2021. Characterization of a cytosolic acyl-activating enzyme catalyzing the formation of 4-methylvaleryl-CoA for pogostone biosynthesis in Pogostemon cablin. Plant and Cell Physiology 62: 1556 – 1571.; Edgar RC. 2004. M uscle: a multiple sequence alignment method with reduced time and space complexity. BMC Bioinformatics 5: 113.; Halkier BA, Gershenzon J. 2006. Biology and biochemistry of glucosinolates. Annual Review of Plant Biology 57: 303 – 333.; He Y, Cheng J, He Y, Yang B, Cheng Y, Yang C, Zhang H, Wang Z. 2019. Influence of isopropylmalate synthase OsIPMS1 on seed vigour associated with amino acid and energy metabolism in rice. Plant Biotechnology Journal 17: 322 – 337.; Hu G, Peng C, Xie X, Zhang S, Cao X. 2017. Availability, pharmaceutics, security, pharmacokinetics, and pharmacological activities of patchouli alcohol. Evidence-Based Complementary and Alternative Medicine: eCAM 2017: 4850612.; Huang SH, Xian JD, Kong SZ, Li YC, Xie JH, Lin J, Chen JN, Wang HF, Su ZR. 2014. Insecticidal activity of pogostone against Spodoptera litura and Spodoptera exigua (Lepidoptera: noctuidae). Pest Management Science 70: 510 – 516.; Jones DT, Taylor WR, Thornton JM. 1992. The rapid generation of mutation data matrices from protein sequences. Computer Applications in the Biosciences 8: 275 – 282.; Jumper J, Evans R, Pritzel A, Green T, Figurnov M, Ronneberger O, Tunyasuvunakool K, Bates R, Žídek A, Potapenko A et al. 2021. Highly accurate protein structure prediction with A lpha F old. Nature 596: 583 – 589.; Junren C, Xiaofang X, Mengting LI, Qiuyun X, Gangmin LI, Huiqiong Z, Guanru C, Xin XU, Yanpeng Y, Fu P et al. 2021. Pharmacological activities and mechanisms of action of Pogostemon cablin Benth: a review. Chinese Medicine 16: 5.
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12Academic Journal
المؤلفون: Chen, Jing, Liu, Lang, Wang, Ying, Li, Zhengguo, Wang, Guodong, Kraus, George, Pichersky, Eran, Xu, Haiyang
المساهمون: Chemistry, Ames Laboratory
المصدر: https://doi.org/10.1093/pcp/pcab111.
مصطلحات موضوعية: 4-Methylvaleric acid, 4-Methylvaleryl-CoA, Acyl-activating enzyme, Branched-chain fatty acid, Pogostemon cablin, Pogostone
وصف الملف: application/pdf
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13
المؤلفون: Zhengguo Li, Lang Liu, Eran Pichersky, Jing Chen, George A. Kraus, Guodong Wang, Ying Wang, Haiyang Xu
المصدر: Plant and Cell Physiology
مصطلحات موضوعية: Physiology, Plant Science, AcademicSubjects/SCI01180, 4-Methylvaleryl-CoA, law.invention, Pogostemon cablin, chemistry.chemical_compound, Biosynthesis, law, Branched-chain fatty acid, Coenzyme A Ligases, Oils, Volatile, Regular Paper, Amino Acid Sequence, Pogostone, Essential oil, Phylogeny, Plant Proteins, chemistry.chemical_classification, biology, AcademicSubjects/SCI01210, Cell Biology, General Medicine, Peroxisome, biology.organism_classification, In vitro, Pogostemon, Cytosol, Enzyme, chemistry, Biochemistry, 4-Methylvaleric acid •, Acyl-activating enzyme, Sequence Alignment
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14
المؤلفون: Yaoying Zeng, Lian Zhou, Zi-Ren Su, Jingjin He, Xiao-Ping Lai, Jiyan Su, Yu-Cui Li
المصدر: Molecular Medicine Reports
مصطلحات موضوعية: Cytotoxicity, Immunologic, Male, 0301 basic medicine, Cancer Research, Cell Survival, T-Lymphocytes, T cell, Apoptosis, Lymphocyte proliferation, Pharmacology, Lymphocyte Activation, Biochemistry, Immunophenotyping, Mice, 03 medical and health sciences, 0302 clinical medicine, Immune system, Oils, Volatile, Genetics, medicine, Animals, inactivation, IL-2 receptor, Cytotoxicity, Molecular Biology, immunosuppression, biology, Plant Extracts, Cell Cycle, pogostone, Interleukin, Articles, Molecular biology, Pogostemon, 030104 developmental biology, medicine.anatomical_structure, Oncology, Concanavalin A, biology.protein, Cytokines, Molecular Medicine, Inflammation Mediators, Immunosuppressive Agents, 030215 immunology
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15
المؤلفون: Waikit Leong, Guoxin Huang, Imran Khan, Wenrui Xia, Yucui Li, Yuhong Liu, Xiaoang Li, Ruixuan Han, Ziren Su, W. L. Wendy Hsiao
مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, patchouli essential oil, patchouli alcohol, pogostone, β-patchoulene, gut microbiota
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16Academic JournalDetermination and Distribution Study of Pogostone in Rat Tissues by Ultra-Fast Liquid Chromatography
المؤلفون: Chen, HM, Wang, L, Wu, XL, Li, CW, Xie, YL, Liu, YH, Liang, YZ, Chen, XY, Lai, XP, Chen, JN, Li, YC, Su, ZR
المصدر: Tropical Journal of Pharmaceutical Research; Vol 14, No 2 (2015); 279-286 ; 1596-9827 ; 1596-5996
مصطلحات موضوعية: Ultra-fast liquid chromatography, Tissue distribution, Pogostone, Honokiol, Rats
وصف الملف: application/pdf
Relation: http://www.ajol.info/index.php/tjpr/article/view/114537/104225; http://www.ajol.info/index.php/tjpr/article/view/114537
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17Academic Journal
المؤلفون: Li, Yucui, Su, Ziren, Lin, Shuhai, Li, Chuwen, Zhao, Ya, Gao, Xiang, Lai, Yongquan, Wu, Xiaoli, Wu, Hanzhi, Cai, Zongwei, Lai, Xiaoping
المصدر: HKBU Staff Publication
مصطلحات موضوعية: hydroxylation, LC-MS, metabolites, orbitrap, oxidation, pogostone, rat liver, Department of Chemistry
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18Academic Journal
المؤلفون: Liu, Xin Chao1, Liu, Qiyong2, Chen, Han1, Liu, Qi Zhi1, Jiang, Shi Yao1, Liu, Zhi Long1,1
المصدر: Journal of Medical Entomology 52(1):86-92. 2015