-
1
المؤلفون: Sander Bekeschus, Sanjeev Kumar Sagwal
المصدر: Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)مصطلحات موضوعية: Premature aging, Aging, Electrochemotherapy, medicine.medical_treatment, Photodynamic therapy, Review Article, Biochemistry, medicine, Animals, Humans, Melanoma, Physical Therapy Modalities, QH573-671, Radiotherapy, business.industry, Cancer, Cell Biology, General Medicine, medicine.disease, Radiation therapy, Oxidative Stress, Pleiotropy (drugs), Photochemotherapy, Cancer research, Skin cancer, Cytology, Reactive Oxygen Species, business
-
2
المؤلفون: James K. Liao, C. Noel Bairey Merz, Janet Wei
المصدر: Circulation
مصطلحات موضوعية: Statin, business.industry, medicine.drug_class, Inflammation, medicine.disease, Bioinformatics, Article, Preeclampsia, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Pleiotropy (drugs), Physiology (medical), medicine, medicine.symptom, Cardiology and Cardiovascular Medicine, business
-
3
المؤلفون: Gurjasmine Kaur, Archana Bhatnagar, Aman Sharma
المصدر: Autoimmunity. 54:385-397
مصطلحات موضوعية: Autoimmune disease, Kelch-Like ECH-Associated Protein 1, NF-E2-Related Factor 2, business.industry, Mechanism (biology), Immunology, Inflammation, Disease, medicine.disease, Bioinformatics, medicine.disease_cause, KEAP1, Antioxidants, Arthritis, Rheumatoid, Oxidative Stress, Pleiotropy (drugs), Rheumatoid arthritis, medicine, Humans, Immunology and Allergy, medicine.symptom, business, Oxidative stress, Signal Transduction
-
4
المؤلفون: Changrui Xiao, Carlos Ferreira, Francis Rossignol, Frédéric M. Vaz
المصدر: Journal of inherited metabolic disease. 44(4):809-825
مصطلحات موضوعية: Cardiolipins, Phospholipid, Biology, Phosphatidylinositols, mitochondrial membrane biogenesis, chemistry.chemical_compound, complex lipids, Genetics, Cardiolipin, Homeostasis, Humans, Genetics (clinical), phospholipids, sphingolipids, Genetic heterogeneity, Lipid metabolism, Metabolism, phosphoinositides, Lipid Metabolism, Lipids, Sphingolipid, Mitochondria, Cell biology, Metabolic pathway, Phenotype, Pleiotropy (drugs), chemistry, lipids (amino acids, peptides, and proteins), Metabolic Networks and Pathways
-
5
المؤلفون: Pablo Yubero, Juan F. Poyatos
المصدر: Molecular Biology and Evolution
مصطلحات موضوعية: Computational biology, Biology, AcademicSubjects/SCI01180, RNAP, 03 medical and health sciences, chemistry.chemical_compound, RNA polymerase, pleiotropy, Escherichia coli, Genetics, Transcriptional regulation, Set (psychology), Molecular Biology, Gene, Discoveries, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, 0303 health sciences, 030306 microbiology, AcademicSubjects/SCI01130, Robustness (evolution), DNA-Directed RNA Polymerases, fitness costs, Pleiotropy (drugs), chemistry, Mutation, Mutation (genetic algorithm), Identification (biology)
-
6
المؤلفون: Danielle C. Lynch, A. Micheil Innes
المصدر: American Journal of Medical Genetics Part A. 185:2653-2669
مصطلحات موضوعية: Genetic heterogeneity, History, 20th Century, Biology, medicine.disease, History, 21st Century, VACTERL association, Congenital Abnormalities, Pleiotropy (drugs), Evolutionary biology, Genetics, medicine, Etiology, Chromosomes, Human, Humans, Abnormalities, Multiple, Gene-Environment Interaction, Genetic Predisposition to Disease, Dubowitz syndrome, Genetics (clinical), Exome sequencing
-
7
المؤلفون: Narayan Ramasubbu, Chris F. Kemerer, Shivendu Pratap Singh
المصدر: Journal of Operations Management. 67:680-703
مصطلحات موضوعية: Dominant design, Modularity (networks), Pleiotropy (drugs), business.industry, Computer science, Strategy and Management, Product management, Management Science and Operations Research, Technology innovation, Software engineering, business, Product architecture, Industrial and Manufacturing Engineering
-
8
المؤلفون: James Rini, Jennifer S. Yokoyama, Salvatore Spina, Joel H. Kramer, Bruce L. Miller, Ethan G. Geier, Adam L. Boxer, Breton M Asken, Katherine P. Rankin
المصدر: Neurocase. 27:120-128
مصطلحات موضوعية: 05 social sciences, Neuropathology, Biology, medicine.disease, eye diseases, 050105 experimental psychology, Progressive supranuclear palsy, 03 medical and health sciences, 0302 clinical medicine, Pleiotropy (drugs), Arts and Humanities (miscellaneous), medicine, Genetic Pleiotropy, Corticobasal degeneration, 0501 psychology and cognitive sciences, Neurology (clinical), Neuroscience, Pathological, 030217 neurology & neurosurgery, Frontotemporal dementia
-
9
المؤلفون: Gillian P. Johnson, Uche Agwuegbo, Kim Jonas
المصدر: Current Opinion in Endocrine and Metabolic Research. 16:43-50
مصطلحات موضوعية: 0301 basic medicine, Mechanism (biology), Chemistry, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Functional impact, SUPERFAMILY, Computational biology, Signal pathway, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Pleiotropy (drugs), Receptor, hormones, hormone substitutes, and hormone antagonists, G protein-coupled receptor
-
10
المؤلفون: Jordan W. Smoller, Phil Lee, Yen-Chen Anne Feng
المصدر: Biol Psychiatry
مصطلحات موضوعية: 0301 basic medicine, Nosology, Multifactorial Inheritance, medicine.medical_specialty, Genome-wide association study, Biology, Genetic correlation, Article, 03 medical and health sciences, 0302 clinical medicine, Genetic variation, medicine, Humans, Genetic Predisposition to Disease, Psychiatry, Biological Psychiatry, Psychiatric genetics, Genetics, Mental Disorders, Genomics, Genetic architecture, Phenotype, 030104 developmental biology, Pleiotropy (drugs), 030217 neurology & neurosurgery, Genome-Wide Association Study, Psychopathology
-
11
المؤلفون: Josh C. Denny, Yong Chen, Ruowang Li, Xinyuan Zhang, Patrick M. A. Sleiman, Rui Duan, Thomas Lumley, Marylyn D. Ritchie, David Carrell, Christopher R. Bauer, Jason H. Moore, Wei-Qi Wei, Jonathan D. Mosley, Georgia L. Wiesner, Robert J. Carroll, Hakon Hakonarson, Digna R. Velez Edwards, Jordan W. Smoller, Sarah A. Pendergrass
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, Databases, Factual, Statistical methods, Computer science, Science, General Physics and Astronomy, Health records, Models, Biological, Polymorphism, Single Nucleotide, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Genetic Pleiotropy, Electronic Health Records, Humans, Generalizability theory, Statistical hypothesis testing, Lossless compression, Multidisciplinary, Communication, Genetic data, General Chemistry, Data science, Summary statistics, Phenotype, 030104 developmental biology, Pleiotropy (drugs), Privacy, Data integration, 030217 neurology & neurosurgery, Genome-Wide Association Study
-
12
المؤلفون: Shiguo Liu, Lulu Xu, Cheng Zhang, Fengyuan Che, Xueping Zheng
المصدر: Developmental Neurobiology
مصطلحات موضوعية: 0301 basic medicine, Autism Spectrum Disorder, Review Article, Neuropathology, Biology, Tourette syndrome, Chromatin remodeling, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Developmental Neuroscience, Intellectual Disability, Intellectual disability, Transcriptional regulation, medicine, Animals, histone methylation, Epigenetics, Review Articles, neurodevelopment, medicine.disease, DNA-Binding Proteins, 030104 developmental biology, Pleiotropy (drugs), gene pleiotropy, Neurodevelopmental Disorders, Autism spectrum disorder, Neuroscience, 030217 neurology & neurosurgery, Ash1l
-
13
المؤلفون: Carolin Koriath, Nick C. Fox, Sarah J. Tabrizi, Jonathan D. Rohrer, Natalie S. Ryan, Jonathan M. Schott, Simon Mead, Henry Houlden, Joanna Kenny
المصدر: Nature Reviews Neurology. 17:23-36
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, medicine.diagnostic_test, Genetic heterogeneity, business.industry, medicine.disease, Test (assessment), Clinical trial, Data sharing, 03 medical and health sciences, Cellular and Molecular Neuroscience, 030104 developmental biology, 0302 clinical medicine, Pleiotropy (drugs), medicine, Dementia, Neurology (clinical), Family history, Intensive care medicine, business, 030217 neurology & neurosurgery, Genetic testing
-
14
المؤلفون: Gilbert Ho, Makoto Hashimoto, Eliezer Masliah, Takato Takenouchi, Masaaki Waragai, Shuei Sugama, Ryoko Wada, Yoshiki Takamatsu
المصدر: Journal of Alzheimer's Disease
مصطلحات موضوعية: 0301 basic medicine, Aging, medicine.medical_treatment, amyloidogenic evolvability, Disease, amyloid-β, antagonistic pleiotropy, Bioinformatics, 03 medical and health sciences, 0302 clinical medicine, Alzheimer Disease, medicine, Humans, Therapeutic strategy, Amyloid beta-Peptides, adiponectin, Adiponectin, Aβ immunotherapy, business.industry, Mechanism (biology), General Neuroscience, Neurotoxicity, Brain, adiponectin paradox, General Medicine, Immunotherapy, medicine.disease, Clinical trial, Psychiatry and Mental health, Clinical Psychology, 030104 developmental biology, Pleiotropy (drugs), Commentary, Geriatrics and Gerontology, business, Alzheimer’s disease, hormones, hormone substitutes, and hormone antagonists, 030217 neurology & neurosurgery
-
15
المؤلفون: Sandra M. Sancho-Martínez, Consuelo Agüeros-Blanco, Víctor Blanco-Gozalo, Marta Prieto, Alfredo G. Casanova, Manuel Arias, Yaremi Quiros, Francisco J. López-Hernández, Adalberto Benito-Hernández, Carlos Martínez-Salgado, C. Gómez-Alamillo, Ana I. Morales, M.A. Ramos-Barron
المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reportsمصطلحات موضوعية: Nephrology, Male, medicine.medical_specialty, Urinary system, 030232 urology & nephrology, lcsh:Medicine, 030204 cardiovascular system & hematology, Kidney, urologic and male genital diseases, Article, 03 medical and health sciences, 0302 clinical medicine, Medical research, Internal medicine, medicine, Humans, Cell Lineage, Intensive care medicine, lcsh:Science, Pathological, Multidisciplinary, Kidney diseases, business.industry, G(M2) Activator Protein, lcsh:R, Acute kidney injury, Acute Kidney Injury, Middle Aged, medicine.disease, female genital diseases and pregnancy complications, Pleiotropy (drugs), Cohort, Etiology, Biomarker (medicine), Female, lcsh:Q, business, Biomarkers, Chaperonin Containing TCP-1
-
16
المؤلفون: David Millrine, Robert H. Jenkins, Simon Jones, Stuart T. O. Hughes
مصطلحات موضوعية: biology, Interleukin-6, medicine.medical_treatment, Biophysics, Cell Biology, Biochemistry, STAT Transcription Factors, Cytokine, Pleiotropy (drugs), Signalling, Structural Biology, Genetics, medicine, biology.protein, Cytokines, Epigenetics, Cues, Enhancer, Interleukin 6, Molecular Biology, Neuroscience, Transcription factor, Tissue homeostasis, Janus Kinases, Signal Transduction
وصف الملف: application/pdf
-
17
المؤلفون: M. Satny, Jaroslav A. Hubacek, Michal Vrablík
المصدر: Current Atherosclerosis Reports. 23
مصطلحات موضوعية: Vascular disease, business.industry, Interleukin, Inflammation, Bioinformatics, medicine.disease, Clinical trial, Canakinumab, Pleiotropy (drugs), Drug class, medicine, medicine.symptom, Lipid modification, Cardiology and Cardiovascular Medicine, business, medicine.drug
-
18
المؤلفون: William Coath, Susie M.D. Henley, Jonathan M. Schott, Sarah E Keuss, John P Grogan, Marcus Richards, Masud Husain, Jennifer M. Nicholas, Carole H. Sudre, Nick C. Fox, Ivanna M. Pavisic, Thomas D. Parker, Ian B. Malone, Sebastian J. Crutch, Kirsty Lu, David M. Cash, Christopher A. Lane, Sarah M Buchanan, Ashvini Keshavan, Sarah-Naomi James, Andrew Wong, Yoni Pertzov, Heidi Murray-Smith
المساهمون: Radiology and nuclear medicine
المصدر: Nature Aging, 1(11), 1002-1009. Springer
Lu, K, Nicholas, J M, Pertzov, Y, Grogan, J, Husain, M, Pavisic, I M, James, S-N, Parker, T D, Lane, C A, Keshavan, A, Keuss, S E, Buchanan, S M, Murray-Smith, H, Cash, D M, Malone, I B, Sudre, C H, Coath, W, Wong, A, Henley, S M D, Fox, N C, Richards, M, Schott, J M & Crutch, S J 2021, ' Dissociable effects of APOE ε4 and β-amyloid pathology on visual working memory ', Nature Aging, vol. 1, no. 11, pp. 1002-1009 . https://doi.org/10.1038/s43587-021-00117-4مصطلحات موضوعية: Aging, Pathology, medicine.medical_specialty, education.field_of_study, Recall, business.industry, Working memory, Population, Neuroscience (miscellaneous), Disease, Pleiotropy (drugs), β amyloid, Genotype, Cohort, Medicine, Geriatrics and Gerontology, business, education
وصف الملف: application/pdf
-
19Volatile social environments can favour investments in quality over quantity of social relationships
المؤلفون: Thomas G. Aubier, Hanna Kokko
مصطلحات موضوعية: education.field_of_study, Social network, business.industry, Bond, media_common.quotation_subject, Population, Microeconomics, Social group, Pleiotropy (drugs), Social relationship, Quality (business), business, education, Reciprocal, media_common
-
20
المؤلفون: Lin Chen, Jin Liu, Qing Cheng
مصطلحات موضوعية: Genetics, Pleiotropy (drugs), Genetic etiology, Mendelian randomization, Biology, Outcome (probability)