المؤلفون: Johanna Helena Kattenberg, Mathijs Mutsaers, Van Hong Nguyen, Thi Hong Ngoc Nguyen, Arlette Umugwaneza, Maria Lara-Escandell, Xuan Xa Nguyen, Thi Huong Binh Nguyen, Anna Rosanas-Urgell

المصدر: Frontiers in Genetics, Vol 15 (2024)

مصطلحات موضوعية: Plasmodium falciparum, malaria molecular surveillance, drug resistance, Vietnam, artemisinin resistance, piperaquine resistance, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2024.1478706/full; https://doaj.org/toc/1664-8021

URL الوصول: https://doaj.org/article/dfa7a0669a9941eaa813980f4747cfee

المؤلفون: Nonlawat Boonyalai, Kirakarn Kirativanich, Chatchadaporn Thamnurak, Chantida Praditpol, Brian A. Vesely, Mariusz Wojnarski, John S. Griesenbeck, Norman C. Waters

المصدر: Malaria Journal, Vol 21, Iss 1, Pp 1-14 (2022)

مصطلحات موضوعية: Exonuclease, Gene editing, Malaria, Piperaquine resistance, Plasmodium falciparum, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-2875

URL الوصول: https://doaj.org/article/1ceb154d913a401e96ce0e42e8665416

المؤلفون: Nonlawat Boonyalai, Brian A. Vesely, Chatchadaporn Thamnurak, Chantida Praditpol, Watcharintorn Fagnark, Kirakarn Kirativanich, Piyaporn Saingam, Chaiyaporn Chaisatit, Paphavee Lertsethtakarn, Panita Gosi, Worachet Kuntawunginn, Pattaraporn Vanachayangkul, Michele D. Spring, Mark M. Fukuda, Chanthap Lon, Philip L. Smith, Norman C. Waters, David L. Saunders, Mariusz Wojnarski

المصدر: Malaria Journal, Vol 19, Iss 1, Pp 1-13 (2020)

مصطلحات موضوعية: Drug combination, Exonuclease, Malaria, PfCRT, Piperaquine resistance, Plasmepsin, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12936-020-03339-w; https://doaj.org/toc/1475-2875

URL الوصول: https://doaj.org/article/d710747a8c344a03b5f36b788ad69daa

المؤلفون: Mie Ikeda (3627083), Makoto Hirai (227542), Shin-Ichiro Tachibana (707681), Toshiyuki Mori (233813), Toshihiro Mita (3500021)

مصطلحات موضوعية: Clinical Microbiology, Medical Bacteriology, Medical Infection Agents (incl. Prions), Medical Virology, piperaquine resistance, mutator, CRT, fitness, Plasmodium berghei, mutants with reduced PPQ susceptibility 2

Relation: https://figshare.com/articles/presentation/Presentation_1_Isolation_of_Mutants_With_Reduced_Susceptibility_to_Piperaquine_From_a_Mutator_of_the_Rodent_Malaria_Parasite_Plasmodium_berghei_pdf/14789694

الاتاحة: https://doi.org/10.3389/fcimb.2021.672691.s002

المؤلفون: Marian Warsame, Abdillahi Mohamed Hassan, Abdikarim Hussein Hassan, Ali Mohamed Jibril, Nimol Khim, Abdulkadir Mohamed Arale, Ahamed Hassan Gomey, Zainab Said Nur, Said Mohamed Osman, Marian Said Mohamed, Ali Abdulrahman, Fahmi Essa Yusuf, Jamal Ghilan Hefzullah Amran, Benoit Witkowski, Pascal Ringwald

المصدر: Malaria Journal, Vol 18, Iss 1, Pp 1-11 (2019)

مصطلحات موضوعية: Artemether–lumefantrine, Dihydroartemisinin–piperaquine, Plasmodium falciparum, Artemisinin resistance, Piperaquine resistance, Somalia, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12936-019-2864-1; https://doaj.org/toc/1475-2875

URL الوصول: https://doaj.org/article/9ddc68a019444e73874c10fbed08d99e

المؤلفون: Mie Ikeda, Makoto Hirai, Shin-Ichiro Tachibana, Toshiyuki Mori, Toshihiro Mita

المصدر: Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)

مصطلحات موضوعية: piperaquine resistance, mutator, CRT, fitness, Plasmodium berghei, mutants with reduced PPQ susceptibility 2, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2021.672691/full; https://doaj.org/toc/2235-2988

URL الوصول: https://doaj.org/article/c7fca02bfdc641f19e04c6eda305d802

المؤلفون: Angana Mukherjee, Selina Bopp, Pamela Magistrado, Wesley Wong, Rachel Daniels, Allison Demas, Stephen Schaffner, Chanaki Amaratunga, Pharath Lim, Mehul Dhorda, Olivo Miotto, Charles Woodrow, Elizabeth A. Ashley, Arjen M. Dondorp, Nicholas J. White, Dyann Wirth, Rick Fairhurst, Sarah K. Volkman

المصدر: Malaria Journal, Vol 16, Iss 1, Pp 1-12 (2017)

مصطلحات موضوعية: Plasmodium falciparum, Artemisinin resistance, pfkelch13, Piperaquine resistance, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12936-017-1845-5; https://doaj.org/toc/1475-2875

URL الوصول: https://doaj.org/article/4c0adcb3ec9d415db0c383296df1ad9e

المؤلفون: Batista, Fernando A, Gyau, Benjamin, Vilacha, Juliana F, Bosch, Soraya S, Lunev, Sergey, Wrenger, Carsten, Groves, Matthew R

المصدر: Batista , F A , Gyau , B , Vilacha , J F , Bosch , S S , Lunev , S , Wrenger , C & Groves , M R 2020 , ' New directions in antimalarial target validation ' , Expert Opinion on Drug Discovery , vol. 15 , no. 2 , pp. 189-202 . https://doi.org/10.1080/17460441.2020.1691996

مصطلحات موضوعية: Protein oligomerisation, malaria, drug target validation, phenotypic mapping, FALCIPARUM DIHYDROOROTATE DEHYDROGENASE, PLASMODIUM-VIVAX DHFR, MALARIA PARASITES, DRUG TARGET, PIPERAQUINE RESISTANCE, TRANSGENE EXPRESSION, NEGATIVE SELECTION, LEAD OPTIMIZATION, GENE-EXPRESSION, BLOOD STAGES

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/af981d6a-2596-4373-82f2-ea974e442613
https://research.rug.nl/en/publications/af981d6a-2596-4373-82f2-ea974e442613
https://doi.org/10.1080/17460441.2020.1691996
https://pure.rug.nl/ws/files/113389231/New_directions_in_antimalarial_target_validation.pdf

المؤلفون: Dhingra, Satish K., Redhi, Devasha, Combrinck, Jill M., Yeo, Tomas, Okombo, John, Henrich, Philipp P., Cowell, Annie N., Gupta, Purva, Stegman, Matthew L., Hoke, Jonathan M., Cooper, Roland A., Winzeler, Elizabeth, Mok, Sachel, Egan, Timothy J., Fidock, David A.

المصدر: Biological Sciences Faculty Publications

مصطلحات موضوعية: Malaria, PfCRT, PLasmodium falciparum, Artemisinin-based combination therapies, Digestive vacuole, Genome editing, Heme detoxification, Piperaquine resistance, Biology, Parasitic Diseases, Pharmacology

وصف الملف: application/pdf

Relation: https://digitalcommons.odu.edu/biology_fac_pubs/211; https://digitalcommons.odu.edu/context/biology_fac_pubs/article/1232/viewcontent/mBio_2017_Dhingra_.pdf

الاتاحة: https://digitalcommons.odu.edu/biology_fac_pubs/211
https://doi.org/10.1128/mBio.00303-17
https://digitalcommons.odu.edu/context/biology_fac_pubs/article/1232/viewcontent/mBio_2017_Dhingra_.pdf

المصدر: Expert Opinion on Drug Discovery. 15(2):189-202

مصطلحات موضوعية: BLOOD STAGES, PLASMODIUM-VIVAX DHFR, Protein oligomerisation, malaria, DRUG TARGET, LEAD OPTIMIZATION, TRANSGENE EXPRESSION, phenotypic mapping, FALCIPARUM DIHYDROOROTATE DEHYDROGENASE, MALARIA PARASITES, drug target validation, PIPERAQUINE RESISTANCE, NEGATIVE SELECTION, GENE-EXPRESSION

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dris___01423::a596c3815e6ff37ee9e453297e7fc3c2
https://research.rug.nl/en/publications/af981d6a-2596-4373-82f2-ea974e442613

المؤلفون: Duru, Valentine, Khim, Nimol, Leang, Rithea, Kim, Saorin, Domergue, Anais, Kloeung, Nimol, Ke, Sopheakvatey, Chy, Sophy, Eam, Rotha, Khean, Chanra, Loch, Kaknika, Ken, Malen, Lek, Dysoley, Beghain, Johann, Ariey, Frédéric, Guerin, Philippe, Huy, Rekol, Mercereau-Puijalon, Odile, Witkowski, Benoit, Ménard, Didier

المساهمون: Institut Pasteur du Cambodge, Pasteur Network (Réseau International des Instituts Pasteur), National Center for Parasitology, Entomology and Malaria Control Phnom Penh, Cambodia (CNM), Département Parasites et Insectes vecteurs - Department of Parasites and Insect Vectors, Institut Pasteur Paris (IP), WorldWide Antimalarial Resistance Network (WWARN), University of Oxford-Churchill Hospital Oxford Centre for Haematology, Centre for Tropical Medicine and Global Health Oxford, UK, Nuffield Department of Medicine Oxford, UK (Big Data Institute), University of Oxford-University of Oxford, This work was funded by grants from Institut Pasteur du Cambodge, USAID and BMGF through the World Health Organization, and Institut Pasteur Paris. PJG is member of the Worldwide Antimalarial Resistance Network supported by the Bill and Melinda Gates Foundation. VD is supported by a doctoral fellowship from the International Division, Institut Pasteur., We thank all patients enrolled in the therapeutic efficacy studies, the health centres staff and the staff from the National Center for Parasitology, Entomology and Malaria Control in Cambodia for their support. We are grateful to Joel Tarning (Mahidol Oxford Tropical Medicine Research Unit, Bangkok, Thailand, Centre for Tropical Medicine, University of Oxford, Oxford, United Kingdom) who performed the piperaquine concentration measurements.

المصدر: ISSN: 1741-7015.

مصطلحات موضوعية: Piperaquine resistance, Treatment failure, Malaria, In-vitro testing, Falciparum, Ex vivo testing, Cambodia, Artemisinin resistance, Artemisinin combination therapies, MESH: Adolescent, MESH: Adult, MESH: Male, MESH: Parasites, MESH: Plasmodium falciparum, MESH: Prospective Studies, MESH: Quinolines, MESH: Retrospective Studies, MESH: Survival Rate, MESH: Treatment Failure, MESH: Treatment Outcome, MESH: Young Adult, MESH: Animals, MESH: Antimalarials, MESH: Artemisinins, MESH: Cambodia, MESH: Female, MESH: Humans, MESH: Malaria, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases

Relation: info:eu-repo/semantics/altIdentifier/pmid/26695060; PUBMED: 26695060; PUBMEDCENTRAL: PMC4688949

الاتاحة: https://hal.science/hal-02560638
https://hal.science/hal-02560638v1/document
https://hal.science/hal-02560638v1/file/Plasmodium%20falciparum%20dihydroartemisinin-piperaquine%20failures%20in%20Cambodia%20are%20associated%20with%20mutant%20K13%20parasites.pdf
https://doi.org/10.1186/s12916-015-0539-5

المؤلفون: Chaiyaporn Chaisatit, Michele D. Spring, Brian Vesely, Watcharintorn Fagnark, Kirakarn Kirativanich, Panita Gosi, Worachet Kuntawunginn, Chatchadaporn Thamnurak, Chantida Praditpol, Mariusz Wojnarski, Paphavee Lertsethtakarn, David L. Saunders, Piyaporn Saingam, Philip L. Smith, Mark M. Fukuda, Norman C. Waters, Pattaraporn Vanachayangkul, Nonlawat Boonyalai, Chanthap Lon

المصدر: Malaria Journal
Malaria Journal, Vol 19, Iss 1, Pp 1-13 (2020)

مصطلحات موضوعية: 0301 basic medicine, Genetic Markers, lcsh:Arctic medicine. Tropical medicine, PfCRT, Genotype, lcsh:RC955-962, 030106 microbiology, Plasmodium falciparum, Drug Resistance, Plasmepsin, Drug resistance, Piperaquine resistance, Biology, Lumefantrine, Exonuclease, lcsh:Infectious and parasitic diseases, 03 medical and health sciences, chemistry.chemical_compound, Antimalarials, Chloroquine, Piperaquine, parasitic diseases, medicine, lcsh:RC109-216, Drug combination, Quinine, Mefloquine, Research, biology.organism_classification, Virology, Malaria, 030104 developmental biology, Infectious Diseases, Phenotype, Parasitology, chemistry, Quinolines, Cambodia, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2abe0b017d6c6d215a5973835f3a27d3
https://doi.org/10.21203/rs.3.rs-22444/v3

المؤلفون: Mie Ikeda (3627083), Makoto Hirai (227542), Shin-Ichiro Tachibana (707681), Toshiyuki Mori (233813), Toshihiro Mita (3500021)

مصطلحات موضوعية: Clinical Microbiology, Medical Bacteriology, Medical Infection Agents (incl. Prions), Medical Virology, piperaquine resistance, mutator, CRT, fitness, Plasmodium berghei, mutants with reduced PPQ susceptibility 2

Relation: https://figshare.com/articles/figure/Image_1_Isolation_of_Mutants_With_Reduced_Susceptibility_to_Piperaquine_From_a_Mutator_of_the_Rodent_Malaria_Parasite_Plasmodium_berghei_tif/14789691

الاتاحة: https://doi.org/10.3389/fcimb.2021.672691.s001

المؤلفون: Mie Ikeda (3627083), Makoto Hirai (227542), Shin-Ichiro Tachibana (707681), Toshiyuki Mori (233813), Toshihiro Mita (3500021)

مصطلحات موضوعية: Clinical Microbiology, Medical Bacteriology, Medical Infection Agents (incl. Prions), Medical Virology, piperaquine resistance, mutator, CRT, fitness, Plasmodium berghei, mutants with reduced PPQ susceptibility 2

Relation: https://figshare.com/articles/dataset/Table_2_Isolation_of_Mutants_With_Reduced_Susceptibility_to_Piperaquine_From_a_Mutator_of_the_Rodent_Malaria_Parasite_Plasmodium_berghei_xlsx/14789700

الاتاحة: https://doi.org/10.3389/fcimb.2021.672691.s004

المؤلفون: Mie Ikeda, Makoto Hirai, Shin-Ichiro Tachibana, Toshiyuki Mori, Toshihiro Mita

مصطلحات موضوعية: Clinical Microbiology, Medical Bacteriology, Medical Infection Agents (incl. Prions), Medical Virology, piperaquine resistance, mutator, CRT, fitness, Plasmodium berghei, mutants with reduced PPQ susceptibility 2

Relation: https://figshare.com/articles/dataset/Table_3_Isolation_of_Mutants_With_Reduced_Susceptibility_to_Piperaquine_From_a_Mutator_of_the_Rodent_Malaria_Parasite_Plasmodium_berghei_xlsx/14789703

الاتاحة: https://doi.org/10.3389/fcimb.2021.672691.s005
https://figshare.com/articles/dataset/Table_3_Isolation_of_Mutants_With_Reduced_Susceptibility_to_Piperaquine_From_a_Mutator_of_the_Rodent_Malaria_Parasite_Plasmodium_berghei_xlsx/14789703

المؤلفون: Juliana F Vilacha, Fernando de Assis Batista, Carsten Wrenger, Sergey Lunev, Soraya S Bosch, Benjamin Gyau, Matthew Groves

المصدر: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

مصطلحات موضوعية: BLOOD STAGES, Plasmodium, PLASMODIUM-VIVAX DHFR, Computer science, Population, Drug target, Druggability, Aspartate metabolism, Computational biology, Validation Studies as Topic, LEAD OPTIMIZATION, TRANSGENE EXPRESSION, Antimalarials, 03 medical and health sciences, 0302 clinical medicine, Drug Development, MALARIA PARASITES, Drug Discovery, medicine, Animals, Humans, education, PIPERAQUINE RESISTANCE, NEGATIVE SELECTION, GENE-EXPRESSION, 030304 developmental biology, 0303 health sciences, education.field_of_study, Drug discovery, Protein oligomerisation, DRUG TARGET, POLIPEPTÍDEOS, medicine.disease, Malaria, Drug development, phenotypic mapping, FALCIPARUM DIHYDROOROTATE DEHYDROGENASE, Proof of concept, 030220 oncology & carcinogenesis, drug target validation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa441dc06eb1da8d3efd735dafa160e

المؤلفون: Jamal Ghilan Hefzullah Amran, Marian Warsame, Zainab Said Nur, Ahamed Hassan Gomey, Fahmi Essa Yusuf, Abdillahi Mohamed Hassan, Abdulkadir Mohamed Arale, Ali Mohamed Jibril, Abdikarim Hussein Hassan, Said Mohamed Osman, Benoit Witkowski, Pascal Ringwald, Nimol Khim, Marian Said Mohamed, Ali Abdulrahman

المساهمون: Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), World Health Organization [Mogadishu, Somalia] (WHO Somalia), Ministry of Health and Human Services [Somalia], Jowhar Hospital, Malaria Molecular Epidemiology, Institut Pasteur du Cambodge, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), The studies were funded by the Bill & Melinda Gates Foundation (Grant No. OPP1140599).

المصدر: Malaria Journal
Malaria Journal, BioMed Central, 2019, 18 (1), pp.231. ⟨10.1186/s12936-019-2864-1⟩
Malaria Journal, Vol 18, Iss 1, Pp 1-11 (2019)

مصطلحات موضوعية: Male, Artemether/lumefantrine, Piperaquine resistance, 0302 clinical medicine, Dihydroartemisinin/piperaquine, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, MESH: Child, 030212 general & internal medicine, Malaria, Falciparum, Artemisinin, Child, Prospective cohort study, MESH: Plasmodium falciparum, MESH: Middle Aged, MESH: Somalia, biology, MESH: Malaria, Falciparum, Middle Aged, MESH: Infant, Artemisinins, 3. Good health, Infectious Diseases, Artemisinin resistance, MESH: Young Adult, Child, Preschool, Quinolines, Dihydroartemisinin–piperaquine, Female, MESH: Quinolines, medicine.drug, Adult, medicine.medical_specialty, lcsh:Arctic medicine. Tropical medicine, Adolescent, lcsh:RC955-962, MESH: Artemether, Lumefantrine Drug Combination, Somalia, 030231 tropical medicine, Plasmodium falciparum, lcsh:Infectious and parasitic diseases, Antimalarials, Young Adult, 03 medical and health sciences, Internal medicine, parasitic diseases, MESH: Artemisinins, medicine, Humans, lcsh:RC109-216, MESH: Adolescent, MESH: Humans, business.industry, Research, Artemether, Lumefantrine Drug Combination, MESH: Child, Preschool, Infant, MESH: Adult, biology.organism_classification, medicine.disease, MESH: Antimalarials, MESH: Male, Parasitology, Tropical medicine, business, Artemether–lumefantrine, MESH: Female, Malaria

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f57ce91df5cbb746ec9fbed0195e64
https://hal.archives-ouvertes.fr/hal-03494810/file/s12936-019-2864-1.pdf

المؤلفون: Jonathan M. Hoke, Purva Gupta, Annie N. Cowell, David A. Fidock, Sachel Mok, Roland A. Cooper, Timothy J. Egan, Tomas Yeo, Satish K. Dhingra, Elizabeth A. Winzeler, Philipp P. Henrich, Matthew L. Stegman, Jill M. Combrinck, Devasha Redhi, John Okombo

المصدر: mBio, Vol 8, Iss 3 (2017)
mBio
mBio, Vol 8, Iss 3, p e00303-17 (2017)

مصطلحات موضوعية: 0301 basic medicine, PfCRT, medicine.medical_treatment, Plasmodium falciparum, Drug Resistance, Protozoan Proteins, malaria, Dihydroartemisinin, Amodiaquine, Drug resistance, Biology, Microbiology, Lethal Dose 50, Antimalarials, 03 medical and health sciences, artemisinin-based combination therapies, Chloroquine, Virology, Piperaquine, parasitic diseases, medicine, Humans, Protein Isoforms, genome editing, Malaria, Falciparum, Artemisinin, Gene Editing, piperaquine resistance, Hemozoin, Membrane Transport Proteins, digestive vacuole, biology.organism_classification, Artemisinins, QR1-502, 3. Good health, 030104 developmental biology, heme detoxification, Mutation, Quinolines, Multidrug Resistance-Associated Proteins, Cambodia, Research Article, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5117d8ae4c68acbf35a2b494bed709fe
https://doi.org/10.1128/mbio.00303-17

المؤلفون: Jeremy Farrar, Nicholas J. White, Le Thanh Dong, Nguyen Thuy Nha-Ca, Nguyen Thi Kim Tuyen, Nguyen Thuy-Nhien, Guy E. Thwaites, Ngo Viet Thanh, Tran Tinh Hien, Nguyen Thanh Tong, Huynh Hong Quang, Marcel Wolbers

المصدر: Malaria Journal

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Time Factors, Adolescent, Endemic Diseases, 030231 tropical medicine, 030106 microbiology, Plasmodium falciparum, Drug Resistance, Drug resistance, Piperaquine resistance, 03 medical and health sciences, Antimalarials, Young Adult, 0302 clinical medicine, Dihydroartemisinin/piperaquine, Piperaquine, Internal medicine, parasitic diseases, medicine, Humans, Treatment Failure, Artemisinin, Malaria, Falciparum, Child, Parasite clearance half-life, biology, Incidence (epidemiology), Incidence, Research, medicine.disease, biology.organism_classification, Virology, Artemisinins, 3. Good health, Infectious Diseases, Parasitology, Vietnam, Artemisinin resistance, Child, Preschool, Quinolines, Female, Malaria, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b919772ba9ecb8c82a324d312bd8d7
http://ora.ox.ac.uk/objects/uuid:

المؤلفون: Anais Domergue, Odile Mercereau-Puijalon, Rithea Leang, Malen Ken, Dysoley Lek, Johann Beghain, Benoit Witkowski, Nimol Khim, Kaknika Loch, Rekol Huy, Frédéric Ariey, Saorin Kim, Chanra Khean, Nimol Kloeung, Valentine Duru, Rotha Eam, Philippe J Guerin, Sophy Chy, Didier Menard, Sopheakvatey Ke

المساهمون: Institut Pasteur du Cambodge, Réseau International des Instituts Pasteur (RIIP), National Center for Parasitology, Entomology and Malaria Control [Phnom Penh, Cambodia] (CNM), Département Parasites et Insectes vecteurs - Department of Parasites and Insect Vectors, Institut Pasteur [Paris], WorldWide Antimalarial Resistance Network (WWARN), University of Oxford [Oxford]-Churchill Hospital Oxford Centre for Haematology, Centre for Tropical Medicine and Global Health [Oxford, UK], Nuffield Department of Medicine [Oxford, UK] (Big Data Institute), University of Oxford [Oxford]-University of Oxford [Oxford], This work was funded by grants from Institut Pasteur du Cambodge, USAID and BMGF through the World Health Organization, and Institut Pasteur Paris. PJG is member of the Worldwide Antimalarial Resistance Network supported by the Bill and Melinda Gates Foundation. VD is supported by a doctoral fellowship from the International Division, Institut Pasteur., We thank all patients enrolled in the therapeutic efficacy studies, the health centres staff and the staff from the National Center for Parasitology, Entomology and Malaria Control in Cambodia for their support. We are grateful to Joel Tarning (Mahidol Oxford Tropical Medicine Research Unit, Bangkok, Thailand, Centre for Tropical Medicine, University of Oxford, Oxford, United Kingdom) who performed the piperaquine concentration measurements., Institut Pasteur [Paris] (IP), University of Oxford-Churchill Hospital Oxford Centre for Haematology, University of Oxford-University of Oxford

المصدر: BMC Medicine
BMC Medicine, BioMed Central, 2015, 13 (1), pp.305. ⟨10.1186/s12916-015-0539-5⟩
BMC Medicine, 2015, 13 (1), pp.305. ⟨10.1186/s12916-015-0539-5⟩

مصطلحات موضوعية: Male, Oncology, MESH: Treatment Failure, Piperaquine resistance, Pharmacology, Dihydroartemisinin/piperaquine, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, MESH: Animals, Prospective Studies, Malaria, Falciparum, Artemisinin, Prospective cohort study, Ex vivo testing, MESH: Plasmodium falciparum, Artemisinin combination therapies, MESH: Treatment Outcome, Medicine(all), 0303 health sciences, biology, MESH: Malaria, Falciparum, General Medicine, Artemisinins, 3. Good health, Survival Rate, Treatment Outcome, Artemisinin resistance, MESH: Young Adult, Quinolines, Female, Cambodia, MESH: Quinolines, Research Article, medicine.drug, Adult, Falciparum, medicine.medical_specialty, Adolescent, MESH: Survival Rate, Plasmodium falciparum, Antimalarials, Young Adult, 03 medical and health sciences, Internal medicine, Piperaquine, parasitic diseases, MESH: Artemisinins, medicine, Animals, Humans, Parasites, Survival rate, In-vitro testing, MESH: Parasites, Retrospective Studies, 030304 developmental biology, MESH: Adolescent, MESH: Humans, 030306 microbiology, business.industry, MESH: Cambodia, MESH: Adult, MESH: Retrospective Studies, medicine.disease, biology.organism_classification, MESH: Antimalarials, MESH: Male, MESH: Prospective Studies, Malaria, Treatment failure, business, MESH: Female, Ex vivo

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2859730365064376e124365485e9dce
https://hal.archives-ouvertes.fr/hal-02560638/document