المؤلفون: Paweł Zajdel (2606617), Katarzyna Grychowska (2658958), Szczepan Mogilski (4490899), Rafał Kurczab (1312479), Grzegorz Satała (805228), Ryszard Bugno (5727881), Tomasz Kos (420162), Joanna Gołębiowska (10291051), Natalia Malikowska-Racia (10875226), Agnieszka Nikiforuk (420161), Séverine Chaumont-Dubel (10291045), Xavier Bantreil (1887601), Maciej Pawłowski (1792099), Jean Martinez (150107), Gilles Subra (1494619), Frédéric Lamaty (1498096), Philippe Marin (460346), Andrzej J. Bojarski (499184), Piotr Popik (292215)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Neuroscience, Physiology, Pharmacology, Cancer, Mental Health, Infectious Diseases, Chemical Sciences not elsewhere classified, rational polypharmacological approach, decent brain penetration, ameliorates cognitive deficits, known procognitive effects, 6 , 3 , displays procognitive properties, 5 ‑ ht, fppq , neutral antagonist 5, procognitive properties, neutral 5, target 5, acting 5, shows selectivity, psychiatric disorders, like symptoms, inhibits phencyclidine, hybridization strategy, gs pathway

Relation: https://figshare.com/articles/journal_contribution/Structure-Based_Design_and_Optimization_of_FPPQ_a_Dual-Acting_5_HT_sub_3_sub_and_5_HT_sub_6_sub_Receptor_Antagonist_with_Antipsychotic_and_Procognitive_Properties/16553317

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00224.s001

المؤلفون: Marcin Drop (6541334), Vittorio Canale (2606626), Séverine Chaumont-Dubel (10291045), Rafał Kurczab (1312479), Grzegorz Satała (805228), Xavier Bantreil (1887601), Maria Walczak (6051134), Paulina Koczurkiewicz-Adamczyk (9981364), Gniewomir Latacz (1570159), Anna Gwizdak (10291048), Martyna Krawczyk (6541325), Joanna Gołębiowska (10291051), Katarzyna Grychowska (2658958), Andrzej J. Bojarski (499184), Agnieszka Nikiforuk (420161), Gilles Subra (1494619), Jean Martinez (150107), Maciej Pawłowski (1792099), Piotr Popik (292215), Philippe Marin (460346), Frédéric Lamaty (1498096), Paweł Zajdel (2606617)

مصطلحات موضوعية: Biochemistry, Neuroscience, Physiology, Pharmacology, Mental Health, Infectious Diseases, Chemical Sciences not elsewhere classified, 5- HT 6 R-operated, scopolamine-induced memory decline, pyrrole -3-carboxamide, canonical indole-like skeleton, novel object recognition test, memory impairment paradigms, 2- phenyl, 5- HT 6 R, attentional set-shifting task

Relation: https://figshare.com/articles/journal_contribution/2_Phenyl_1_i_H_i_pyrrole-3-carboxamide_as_a_New_Scaffold_for_Developing_5_HT_sub_6_sub_Receptor_Inverse_Agonists_with_Cognition-Enhancing_Activity/14199994

الاتاحة: https://doi.org/10.1021/acschemneuro.1c00061.s001

المؤلفون: Piotr Popik (292215), Adam Hogendorf (3896932), Ryszard Bugno (5727881), Shaun Yon-Seng Khoo (459463), Pawel Zajdel (1737517), Natalia Malikowska-Racia (10875226), Agnieszka Nikiforuk (420161), Joanna Golebiowska (6053081)

مصطلحات موضوعية: Behavioral Neuroscience, Time perception, Cognition, Ketamine, Psilocybin, rapid antidepressant, rat

Relation: https://figshare.com/articles/dataset/Dataset_Effects_of_ketamine_optical_isomers_psilocybin_psilocin_and_norpsilocin_on_time_estimation_and_cognition_in_rats/14933127

الاتاحة: https://doi.org/10.6084/m9.figshare.14933127.v1

المؤلفون: Paweł Zajdel (2606617), Katarzyna Grychowska (2658958), Szczepan Mogilski (4490899), Rafał Kurczab (1312479), Grzegorz Satała (805228), Ryszard Bugno (5727881), Tomasz Kos (420162), Joanna Gołębiowska (10291051), Natalia Malikowska-Racia (10875226), Agnieszka Nikiforuk (420161), Séverine Chaumont-Dubel (10291045), Xavier Bantreil (1887601), Maciej Pawłowski (1792099), Jean Martinez (150107), Gilles Subra (1494619), Frédéric Lamaty (1498096), Philippe Marin (460346), Andrzej J. Bojarski (499184), Piotr Popik (292215)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Neuroscience, Physiology, Pharmacology, Cancer, Mental Health, Infectious Diseases, Chemical Sciences not elsewhere classified, rational polypharmacological approach, decent brain penetration, ameliorates cognitive deficits, known procognitive effects, 6 , 3 , displays procognitive properties, 5 ‑ ht, fppq , neutral antagonist 5, procognitive properties, neutral 5, target 5, acting 5, shows selectivity, psychiatric disorders, like symptoms, inhibits phencyclidine, hybridization strategy, gs pathway

Relation: https://figshare.com/articles/dataset/Structure-Based_Design_and_Optimization_of_FPPQ_a_Dual-Acting_5_HT_sub_3_sub_and_5_HT_sub_6_sub_Receptor_Antagonist_with_Antipsychotic_and_Procognitive_Properties/16553323

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00224.s003

المؤلفون: Paweł Zajdel (2606617), Katarzyna Grychowska (2658958), Szczepan Mogilski (4490899), Rafał Kurczab (1312479), Grzegorz Satała (805228), Ryszard Bugno (5727881), Tomasz Kos (420162), Joanna Gołębiowska (10291051), Natalia Malikowska-Racia (10875226), Agnieszka Nikiforuk (420161), Séverine Chaumont-Dubel (10291045), Xavier Bantreil (1887601), Maciej Pawłowski (1792099), Jean Martinez (150107), Gilles Subra (1494619), Frédéric Lamaty (1498096), Philippe Marin (460346), Andrzej J. Bojarski (499184), Piotr Popik (292215)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Neuroscience, Physiology, Pharmacology, Cancer, Mental Health, Infectious Diseases, Chemical Sciences not elsewhere classified, rational polypharmacological approach, decent brain penetration, ameliorates cognitive deficits, known procognitive effects, 6 , 3 , displays procognitive properties, 5 ‑ ht, fppq , neutral antagonist 5, procognitive properties, neutral 5, target 5, acting 5, shows selectivity, psychiatric disorders, like symptoms, inhibits phencyclidine, hybridization strategy, gs pathway

Relation: https://figshare.com/articles/dataset/Structure-Based_Design_and_Optimization_of_FPPQ_a_Dual-Acting_5_HT_sub_3_sub_and_5_HT_sub_6_sub_Receptor_Antagonist_with_Antipsychotic_and_Procognitive_Properties/16553320

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00224.s002

المؤلفون: Paweł Zajdel (2606617), Katarzyna Grychowska (2658958), Szczepan Mogilski (4490899), Rafał Kurczab (1312479), Grzegorz Satała (805228), Ryszard Bugno (5727881), Tomasz Kos (420162), Joanna Gołębiowska (10291051), Natalia Malikowska-Racia (10875226), Agnieszka Nikiforuk (420161), Séverine Chaumont-Dubel (10291045), Xavier Bantreil (1887601), Maciej Pawłowski (1792099), Jean Martinez (150107), Gilles Subra (1494619), Frédéric Lamaty (1498096), Philippe Marin (460346), Andrzej J. Bojarski (499184), Piotr Popik (292215)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Neuroscience, Physiology, Pharmacology, Cancer, Mental Health, Infectious Diseases, Chemical Sciences not elsewhere classified, rational polypharmacological approach, decent brain penetration, ameliorates cognitive deficits, known procognitive effects, 6 , 3 , displays procognitive properties, 5 ‑ ht, fppq , neutral antagonist 5, procognitive properties, neutral 5, target 5, acting 5, shows selectivity, psychiatric disorders, like symptoms, inhibits phencyclidine, hybridization strategy, gs pathway

Relation: https://figshare.com/articles/dataset/Structure-Based_Design_and_Optimization_of_FPPQ_a_Dual-Acting_5_HT_sub_3_sub_and_5_HT_sub_6_sub_Receptor_Antagonist_with_Antipsychotic_and_Procognitive_Properties/16553326

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00224.s004

المؤلفون: Natalia Malikowska-Racia (10875226), Kinga Salat (11050257), Joanna Gdula-Argasinska (11050260), Piotr Popik (292215)

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, Pramipexole, tiagabine, corticosterone, PTSD, trauma, sex, HPA

Relation: https://figshare.com/articles/dataset/DataSheet1_Sex_Pramipexole_and_Tiagabine_Affect_Behavioral_and_Hormonal_Response_to_Traumatic_Stress_in_a_Mouse_Model_of_PTSD_docx/14881299

الاتاحة: https://doi.org/10.3389/fphar.2021.691598.s001