المؤلفون: Pinar Iyidogan, Karen S. Anderson

المصدر: Viruses, Vol 6, Iss 10, Pp 4095-4139 (2014)

مصطلحات موضوعية: HIV-1, antiviral therapy, drug resistance, evolution, lethal mutagenesis, resistance monitoring, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1999-4915/6/10/4095; https://doaj.org/toc/1999-4915

URL الوصول: https://doaj.org/article/b711992f7fb74365b2c7a1278c8626a7

المؤلفون: David F. Stern, Howard S. Hochster, Christos Hatzis, Ja Seok Koo, Jong Woo Lee, Matthew A. Held, Michael Klein, Ramanaiah Mamillapalli, Pinar Iyidogan, Robert E. Means, James T. Platt, Casey G. Langdon

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019211ba1cc80dd5a28fb0d9390b87e3
https://doi.org/10.1158/1535-7163.22509253.v1

المؤلفون: David F. Stern, Howard S. Hochster, Christos Hatzis, Ja Seok Koo, Jong Woo Lee, Matthew A. Held, Michael Klein, Ramanaiah Mamillapalli, Pinar Iyidogan, Robert E. Means, James T. Platt, Casey G. Langdon

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0bea30df2e60ed6b9e8e1348a0c46aaa
https://doi.org/10.1158/1535-7163.c.6539233.v1

المؤلفون: David F. Stern, Howard S. Hochster, Christos Hatzis, Ja Seok Koo, Jong Woo Lee, Matthew A. Held, Michael Klein, Ramanaiah Mamillapalli, Pinar Iyidogan, Robert E. Means, James T. Platt, Casey G. Langdon

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381dbf02a8aaeb9afe47889582cd7d06
https://doi.org/10.1158/1535-7163.22509247.v1

المؤلفون: David F. Stern, Howard S. Hochster, Christos Hatzis, Ja Seok Koo, Jong Woo Lee, Matthew A. Held, Michael Klein, Ramanaiah Mamillapalli, Pinar Iyidogan, Robert E. Means, James T. Platt, Casey G. Langdon

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295a43b14e6e100a99d32679315b9c82
https://doi.org/10.1158/1535-7163.22509235

المؤلفون: Pinar Iyidogan, Karen S. Anderson

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://www.mdpi.com/1999-4915/6/10/4095/pdf/.

مصطلحات موضوعية: HIV-1, antiviral therapy, drug resistance, evolution, lethal mutagenesis

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.657.1297; http://www.mdpi.com/1999-4915/6/10/4095/pdf/

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.657.1297
http://www.mdpi.com/1999-4915/6/10/4095/pdf/

المؤلفون: Ramanaiah Mamillapalli, Casey G. Langdon, Robert E. Means, James T. Platt, Pinar Iyidogan, David F. Stern, Ja Seok Koo, Howard S. Hochster, Matthew A. Held, Jong Woo Lee, Michael J. Klein, Christos Hatzis

المصدر: Molecular Cancer Therapeutics. 16:1041-1053

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, endocrine system diseases, DNA damage, Antineoplastic Agents, Apoptosis, Pharmacology, Biology, medicine.disease_cause, Article, Mice, 03 medical and health sciences, Adenosine Triphosphate, Superoxides, Cell Line, Tumor, medicine, Animals, Humans, Molecular Targeted Therapy, Cell Proliferation, Dose-Response Relationship, Drug, Cell growth, High-Throughput Nucleotide Sequencing, Cancer, Drug Synergism, medicine.disease, Xenograft Model Antitumor Assays, digestive system diseases, Mitochondria, Bromodomain, Pancreatic Neoplasms, Drug Combinations, 030104 developmental biology, Oncology, Neoplastic Stem Cells, Adenocarcinoma, Neddylation, KRAS, Drug Screening Assays, Antitumor, Carcinoma, Pancreatic Ductal, DNA Damage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1beac8e4d6d233d3cd35bb89d4c74496
https://doi.org/10.1158/1535-7163.mct-16-0794

المؤلفون: Arnold Oliphant, Arif E. Cetin, Eugene Tu, Mark C. Wallen, Pinar Iyidogan, Michael Van Nguyen, Yuki Hayashi, Kandaswamy Vijayan

المصدر: ACS sensors. 3(3)

مصطلحات موضوعية: 0301 basic medicine, Fluid Flow and Transfer Processes, Nanohole, Surface Properties, Process Chemistry and Technology, Microfluidics, Bioengineering, Nanotechnology, 02 engineering and technology, DNA, Sequence Analysis, DNA, 021001 nanoscience & nanotechnology, DNA sequencing, 03 medical and health sciences, 030104 developmental biology, Data sequences, Nanolithography, Gold surface, Gold, 0210 nano-technology, Instrumentation, Plasmon, Label free

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21eee2a957c0aa91aa1436c10f0a3bf1
https://pubmed.ncbi.nlm.nih.gov/29488377

المؤلفون: David F. Stern, Ramanaiah Mamillapalli, Marcus Bosenberg, Matthew A. Held, Nicholas Theodosakis, Shaomeng Wang, James T. Platt, Gregoire Vuagniaux, Pinar Iyidogan, Frederic Levy, Casey G. Langdon, Norbert Wiedemann

المصدر: Oncotarget

مصطلحات موضوعية: Lung Neoplasms, Time Factors, Topoisomerase Inhibitors, Apoptosis, Docetaxel, Pharmacology, bromodomain inhibitor, combination therapy, chemistry.chemical_compound, Antineoplastic Combined Chemotherapy Protocols, Mice, Inbred BALB C, NF-kappa B, Drug Synergism, Azepines, Azocines, XIAP, Tumor Burden, Oncology, Paclitaxel, Female, Taxoids, Topoisomerase inhibitor, medicine.drug, Research Paper, Signal Transduction, medicine.drug_class, Ripoptosome, Mice, Nude, Adenocarcinoma of Lung, Biology, Adenocarcinoma, Inhibitor of apoptosis, Irinotecan, Cell Line, Tumor, medicine, Animals, Humans, Benzhydryl Compounds, Cell Proliferation, Dose-Response Relationship, Drug, Cell growth, Triazoles, lung adenocarcinoma, Xenograft Model Antitumor Assays, Bromodomain, SMAC mimetic, chemistry, Camptothecin, Apoptosis Regulatory Proteins, high throughput screening

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a99dbf5debaea7235fdc27ed8e44dfec
http://europepmc.org/articles/PMC4741938

المؤلفون: Marcus Bosenberg, Andrew B. Koo, David F. Stern, Casey G. Langdon, Zongzhi Liu, Matthew A. Held, Pinar Iyidogan, Michael J. Klein, Ramanaiah Mamillapalli, James T. Platt, Katrina Meeth

المصدر: Pigment Cell & Melanoma Research. 28:417-430

مصطلحات موضوعية: Male, Indoles, Skin Neoplasms, endocrine system diseases, Combination therapy, medicine.drug_class, Colorectal cancer, Mutant, Mice, Nude, Dermatology, Quinolones, Pharmacology, Article, General Biochemistry, Genetics and Molecular Biology, Tyrosine-kinase inhibitor, Small Molecule Libraries, Cell Line, Tumor, medicine, Animals, Humans, skin and connective tissue diseases, Melanoma, Protein Kinase Inhibitors, neoplasms, Cell Proliferation, Sulfonamides, Chemistry, MEK inhibitor, Drug Synergism, medicine.disease, digestive system diseases, Neoplasm Proteins, enzymes and coenzymes (carbohydrates), Vemurafenib, Oncology, Drug Resistance, Neoplasm, Cell culture, Mutation, Cancer research, Benzimidazoles, Signal transduction, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f930ff19266a0ddae3915267ce17950
https://doi.org/10.1111/pcmr.12376

المؤلفون: Karen S. Anderson, William L. Jorgensen, Amalendu Prakash Ranjan, Daniel J. Czyzyk, A. Clinton White, Pinar Iyidogan, Jamboor K. Vishwanatha, José A. Cisneros, Alejandro Castellanos-Gonzalez, Anindita Mukerjee

المصدر: Bioorganic & Medicinal Chemistry Letters. 25:2065-2067

مصطلحات موضوعية: Models, Molecular, Antiparasitic, medicine.drug_class, Clinical Biochemistry, Antiprotozoal Agents, Cryptosporidium, Pharmaceutical Science, Biochemistry, Thymidylate synthase, Article, Microbiology, Multienzyme Complexes, parasitic diseases, Drug Discovery, Dihydrofolate reductase, medicine, Potency, Molecular Biology, Cells, Cultured, Binding Sites, biology, Chemistry, Organic Chemistry, Drug Synergism, Thymidylate Synthase, biology.organism_classification, Virology, Tetrahydrofolate Dehydrogenase, Cell culture, Drug delivery, biology.protein, Nanoparticles, Molecular Medicine, Cryptosporidium hominis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd790ba1aa25fdc3c92b1cfe8dfff741
https://doi.org/10.1016/j.bmcl.2015.03.091

المؤلفون: Julian Tirado-Rives, Raymond T. Chung, William L. Jorgensen, Todd J. Sullivan, Ebrahim Mohamed, Christopher M. Bailey, Pinar Iyidogan, Juliana Ruiz-Caro, Roger Hunter, Karen S. Anderson

المصدر: Journal of Medicinal Chemistry. 56:3959-3968

مصطلحات موضوعية: Models, Molecular, Anti-HIV Agents, Oligonucleotides, Virus Replication, Article, Mass Spectrometry, Polyethylene Glycols, Structure-Activity Relationship, chemistry.chemical_compound, X-Ray Diffraction, Drug Discovery, PEG ratio, Humans, Structure–activity relationship, Bifunctional, DNA Primers, virus diseases, Virology, HIV Reverse Transcriptase, In vitro, Reverse transcriptase, chemistry, Viral replication, Drug Design, HIV-1, Reverse Transcriptase Inhibitors, Molecular Medicine, Indicators and Reagents, Linker, Nucleoside, Dinucleoside Phosphates

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b67274493c5213e17c488bd2ecb72d5
https://doi.org/10.1021/jm400160s

المؤلفون: Karen S. Anderson, Pinar Iyidogan

المصدر: Antiviral Research. 95:93-103

مصطلحات موضوعية: Efavirenz, DNA Repair, Anti-HIV Agents, DNA repair, Organophosphonates, Biology, Article, Nucleoside Reverse Transcriptase Inhibitor, chemistry.chemical_compound, Adenosine Triphosphate, Virology, medicine, Humans, Binding site, Tenofovir, Pharmacology, Binding Sites, Reverse-transcriptase inhibitor, Adenine, Molecular biology, HIV Reverse Transcriptase, Reverse transcriptase, Terminator (genetics), chemistry, HIV-1, Primer binding site, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0c9cb93bdd7f13d8d009baff578f9f
https://doi.org/10.1016/j.antiviral.2012.05.012

المؤلفون: Stefan Lutz, Pinar Iyidogan

المصدر: Biochemistry. 47:4711-4720

مصطلحات موضوعية: Models, Molecular, Stereochemistry, Deoxyguanosine kinase, Thymidine Kinase, Biochemistry, Article, Substrate Specificity, chemistry.chemical_compound, Deoxycytidine Kinase, Humans, Nucleotide salvage, Binding Sites, biology, Kinase, Active site, Deoxycytidine kinase, Protein engineering, Protein Structure, Tertiary, Enzyme Activation, Deoxyribonucleoside, Kinetics, Amino Acid Substitution, chemistry, Thymidine kinase, Mutation, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16f68d2ac3ae822d7e4e9878f63cb63
https://doi.org/10.1021/bi800157e

المؤلفون: Pinar Iyidogan, Karen S. Anderson

مصطلحات موضوعية: Cyclopropanes, Efavirenz, Tenofovir, Anti-HIV Agents, Organophosphonates, Context (language use), Drug resistance, Bioinformatics, Treatment failure, Article, chemistry.chemical_compound, Viral sequence, Drug Resistance, Viral, medicine, business.industry, Mechanism (biology), Adenine, Drug Synergism, General Medicine, Reverse transcriptase, Benzoxazines, chemistry, Alkynes, HIV-1, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e33b308b02e20fa8ccdd8f49c99c019
https://europepmc.org/articles/PMC4077986/

المؤلفون: Mahendra D. Chordia, Kathleen M. Frey, Karen S. Anderson, Todd J. Sullivan, Pinar Iyidogan

مصطلحات موضوعية: chemistry.chemical_classification, Organic Chemistry, Cell, Biochemistry, Virology, Molecular biology, Reverse transcriptase, chemistry.chemical_compound, Enzyme, medicine.anatomical_structure, chemistry, Drug Discovery, medicine, Nucleoside triphosphate, Thymidine, IC50, Linker, Nucleoside

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86403be95420faff0badacc8b164c066
https://europepmc.org/articles/PMC4027223/

المؤلفون: Pinar Iyidogan, Adrian S. Ray, Aravind Basavapathruni, Joy Y. Feng, Karen S. Anderson, Ginger E. Dutschman, Guangxiu Dai, Dongyuan Piao, Wolfgang Hinz, Eisuke Murakami, Kathlyn A. Parker, Fei You, David J. Austin

مصطلحات موضوعية: Models, Molecular, Molecular model, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, HIV Infections, Biochemistry, Article, Polyethylene Glycols, chemistry.chemical_compound, Drug Discovery, Humans, Binding site, Bifunctional, Molecular Biology, Binding Sites, Organic Chemistry, Nucleosides, Reverse transcriptase, HIV Reverse Transcriptase, chemistry, Drug Design, HIV-1, Molecular Medicine, Reverse Transcriptase Inhibitors, Nucleoside, Linker, DNA, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7cce71df66bf74954afaa629094222
https://europepmc.org/articles/PMC3580853/

المؤلفون: Pinar Iyidogan, Karen S. Anderson

المصدر: Antiviral Drug Strategies

مصطلحات موضوعية: Genetics, Lethal mutagenesis, Error threshold, Human immunodeficiency virus (HIV), medicine, Mutation frequency, Biology, medicine.disease_cause, Virology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7eb62e7e80584a6d4a22e5416311a05e
https://doi.org/10.1002/9783527635955.ch11

المؤلفون: Pinar Iyidogan, Casey G. Langdon, Matthew A. Held, Claudio Zanna, David F. Stern, Ramanaiah Mamillapalli, Shaomeng Wang, James T. Platt, Mel Sorensen, Marcus Bosenberg, Frédéric Lévy, Nicholas Theodosakis, Denis Robichon, Grégoire Vuagniaux, Norbert Wiedemann

المصدر: Cancer Research. 75:2529-2529

مصطلحات موضوعية: Cancer Research, biology, medicine.drug_class, Topoisomerase, Ripoptosome, Cancer, Pharmacology, Inhibitor of apoptosis, medicine.disease, Bromodomain, XIAP, chemistry.chemical_compound, Oncology, Paclitaxel, chemistry, biology.protein, medicine, Topoisomerase inhibitor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::40dcd30cb26f979b313ec406db6a5c71
https://doi.org/10.1158/1538-7445.am2015-2529

المؤلفون: Christopher M. Bailey, Todd J. Sullivan, Pinar Iyidogan, Julian Tirado-Rives, Raymond Chung, Juliana Ruiz-Caro, Ebrahim Mohamed, William L. Jorgensen, Roger Hunter, Karen S. Anderson

المصدر: Journal of Medicinal Chemistry. 56:8953-8953

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4b802919bd0eaa20079d6b471342d576
https://doi.org/10.1021/jm401535f