المؤلفون: Yan Yuan, Shuxiao Wu, Philip J. R. Day

المصدر: Toxins, Vol 16, Iss 10, p 440 (2024)

مصطلحات موضوعية: Malania oleifera, ribosome-inactivating protein, ricin, amino acid sequences, 3D structure, Medicine

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2072-6651/16/10/440; https://doaj.org/toc/2072-6651

URL الوصول: https://doaj.org/article/44eb97d4150b4082986e64d33f09ba1d

المؤلفون: Natasha Carmichael, Philip J. R. Day

المصدر: Frontiers in Pharmacology, Vol 13 (2022)

مصطلحات موضوعية: transporters, therapeutic index, aptamers, chemical fragments, diffusion, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.852938/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/19c28c43301d44849be082fa74886a0e

المؤلفون: Justine M. Grixti, Duncan Ayers, Philip J. R. Day

المصدر: Non-Coding RNA, Vol 7, Iss 2, p 27 (2021)

مصطلحات موضوعية: miRNA, Drug Delivery, cancer chemoresistance, drug resistance, cell uptake, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2311-553X/7/2/27; https://doaj.org/toc/2311-553X

URL الوصول: https://doaj.org/article/de98bfd6af994a5590e9cee6cad80f20

المؤلفون: Elizabeth L. Bell, Ross Smithson, Siobhan Kilbride, Jake Foster, Florence J. Hardy, Saranarayanan Ramachandran, Aleksander A. Tedstone, Sarah J. Haigh, Arthur A. Garforth, Philip J. R. Day, Colin Levy, Michael P. Shaver, Anthony P. Green

المصدر: Nature Catalysis. 5:673-681

مصطلحات موضوعية: Process Chemistry and Technology, Bioengineering, Biochemistry, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c7e1d2020fa56daaf4656cb9e083de41
https://doi.org/10.1038/s41929-022-00821-3

المؤلفون: Shaowei Zhang, Robert Schwarcz, Derren J. Heyes, Carlo Breda, Christopher David Edlin, Flaviano Giorgini, Nigel S. Scrutton, Girdhar Singh Deora, Colin Levy, Kevin D. Read, Marina Wright Muelas, Douglas B. Kell, David Leys, Benjamin P. Ross, Philip J. R. Day, Alex D Klausing, Stephen O’Hagan, Michiyo Sakuma

المصدر: Communications Biology, Vol 2, Iss 1, Pp 1-10 (2019)
Zhang, S, Sakuma, M, Deora, G S, Levy, C, Klausing, A, Breda, C, Read, K D, Ross, B P, Wright Muelas, M, Day, P, O'Hagan, S, Kell, D, Schwarcz, R, Leys, D, Heyes, D, Giorgini, F & Scrutton, N 2019, ' A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites ', Communications Biology . https://doi.org/10.1038/s42003-019-0520-5
Communications Biology
COMMUNICATIONS BIOLOGY

مصطلحات موضوعية: Kynurenine pathway, Metabolite, Medicine (miscellaneous), Pharmacology, Neuroprotection, Article, General Biochemistry, Genetics and Molecular Biology, Pathogenesis, Mice, 03 medical and health sciences, chemistry.chemical_compound, Kynurenine 3-Monooxygenase, 0302 clinical medicine, Manchester Institute of Biotechnology, medicine, Animals, Neurodegeneration, Enzyme Inhibitors, lcsh:QH301-705.5, X-ray crystallography, 030304 developmental biology, 0303 health sciences, Drug discovery, business.industry, Brain, Neurodegenerative Diseases, Hydrogen Peroxide, Prodrug, medicine.disease, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology, Chemical biology, 3. Good health, chemistry, lcsh:Biology (General), Blood-Brain Barrier, General Agricultural and Biological Sciences, business, 030217 neurology & neurosurgery, Kynurenine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cef15ca27e150c8aaa51693da774887
http://link.springer.com/article/10.1038/s42003-019-0520-5

المؤلفون: Maria Ababi, Nicholas J. Turner, Elizabeth L. Bell, Neil Swainston, Joanna C. Sadler, Andrew Currin, Philip J. R. Day, Jane Kwok, Douglas B. Kell

المصدر: ACS Synthetic Biology
Currin, A, Kwok, J, Sadler, J C, Bell, E L, Swainston, N, Ababi, M, Day, P, Turner, N J & Kell, D B 2019, ' GeneORator: An Effective Strategy for Navigating Protein Sequence Space More Efficiently through Boolean OR-Type DNA Libraries ', ACS Synthetic Biology, vol. 8, no. 6, pp. 1371-1378 . https://doi.org/10.1021/acssynbio.9b00063
Currin, A, Kwok, J, Sadler, J C, Bell, E L, Swainston, N, Ababi, M, Day, P, Turner, N J & Kell, D B 2019, ' GeneORator : An effective strategy for navigating protein sequence space more efficiently through boolean or-type DNA libraries ', ACS Synthetic Biology, vol. 8, no. 6, pp. 1371-1378 . https://doi.org/10.1021/acssynbio.9b00063

مصطلحات موضوعية: 0106 biological sciences, Logical disjunction, biocatalysis, Computer science, Biomedical Engineering, Computational biology, 01 natural sciences, Biochemistry, Genetics and Molecular Biology (miscellaneous), 03 medical and health sciences, chemistry.chemical_compound, Synthetic biology, Protein sequencing, Manchester Institute of Biotechnology, Catalytic Domain, 010608 biotechnology, Amino Acid Sequence, directed evolution, Gene Library, 030304 developmental biology, 0303 health sciences, Genetic diversity, Proteins, protein engineering, General Medicine, Protein engineering, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology, Directed evolution, chemistry, Mutagenesis, Site-Directed, Synthetic Biology, synthetic biology, Directed Molecular Evolution, mutagenesis, DNA, Combinatorial explosion, Research Article

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4318a47b131fa45b42bb0a47b1e4b5fb
https://doi.org/10.1021/acssynbio.9b00063

المؤلفون: Ahmad Sait, Andrew J. Doig, Philip J. R. Day, Cristian Angeli

المصدر: Sait, A, Angeli, C, Doig, A J & Day, P J R 2021, ' Viral Involvement in Alzheimer’s Disease ', ACS Chemical Neuroscience . https://doi.org/10.1021/acschemneuro.0c00719
ACS Chemical Neuroscience

مصطلحات موضوعية: Apolipoprotein E, Physiology, Cognitive Neuroscience, Tau protein, Plaque, Amyloid, Disease, Review, Herpesvirus 1, Human, medicine.disease_cause, Blood–brain barrier, Biochemistry, Pathogenesis, 03 medical and health sciences, blood−brain barrier, 0302 clinical medicine, In vivo, Alzheimer Disease, Medicine, Humans, valacyclovir, Pathogen, 030304 developmental biology, apolipoprotein E, 0303 health sciences, Amyloid beta-Peptides, biology, business.industry, β-amyloid, Herpes Simplex, Neurofibrillary Tangles, Cell Biology, General Medicine, herpes simplex virus, Herpes simplex virus, medicine.anatomical_structure, Immunology, biology.protein, business, Alzheimer’s disease, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9333c2f3cbc161b071779b4b9a7357b0
https://doi.org/10.1021/acschemneuro.0c00719

المؤلفون: Guangping Tai, Parisa Ranjzad, Fiona Marriage, Samrina Rehman, Helen Denley, Jill Dixon, Karen Mitchell, Philip J R Day, Adrian S Woolf

المصدر: PLoS ONE, Vol 8, Iss 11, p e81167 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3832456?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/a0d40cf4e89a4fbcb1b5e4e04b56ccf5

المؤلفون: Philip J. R. Day, Jashan Singh, Philip A. Thomas, Vasyl G. Kravets, Alexander N. Grigorenko, Qi Ge, Fan Wu

المصدر: Wu, F, Singh, J, Thomas, P A, Ge, Q, Kravets, V G, Day, P J & Grigorenko, A N 2020, ' Ultrasensitive and rapid detection of malaria using graphene-enhanced surface plasmon resonance ', 2D Materials, vol. 7, no. 4 . https://doi.org/10.1088/2053-1583/aba88e
2D Materials

مصطلحات موضوعية: Materials science, Graphene, Mechanical Engineering, graphene, Nanotechnology, 02 engineering and technology, General Chemistry, 010402 general chemistry, 021001 nanoscience & nanotechnology, Condensed Matter Physics, 01 natural sciences, Rapid detection, 3. Good health, 0104 chemical sciences, law.invention, Mechanics of Materials, law, General Materials Science, biosensing, Surface plasmon resonance, 0210 nano-technology, Biosensor, surface plasmon resonance

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a859410d4abb34776abffc4d4ffe8b1
https://www.research.manchester.ac.uk/portal/en/publications/ultrasensitive-and-rapid-detection-of-malaria-using-grapheneenhanced-surface-plasmon-resonance(d36b949d-b41c-420c-b532-96fe1b1789e4).html

المؤلفون: Joanna E. Parkes, Anastasia Thoma, Adam P. Lightfoot, Hector Chinoy, Philip J. R. Day, Janine A. Lamb

المصدر: BMC Rheumatology
BMC Rheumatology, Vol 4, Iss 1, Pp 1-9 (2020)

مصطلحات موضوعية: 0301 basic medicine, RM, lcsh:Diseases of the musculoskeletal system, Biology, Dermatomyositis, QH301, 03 medical and health sciences, 0302 clinical medicine, Rheumatology, Downregulation and upregulation, Interferon, microRNA, Gene expression, medicine, 030203 arthritis & rheumatology, Messenger RNA, Skeletal muscle, RNA sequencing, medicine.disease, ADK, Polymyositis, 030104 developmental biology, medicine.anatomical_structure, Cancer research, lcsh:RC925-935, Inclusion body myositis, Idiopathic inflammatory myopathies, medicine.drug, Research Article

وصف الملف: application/pdf; text

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b6ddecb485224d88f66eb63f829288
http://europepmc.org/articles/PMC7285612

المؤلفون: Philip J R Day

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://www.biochemsoctrans.org/content/ppbiost/37/2/424.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1088.8795; http://www.biochemsoctrans.org/content/ppbiost/37/2/424.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1088.8795
http://www.biochemsoctrans.org/content/ppbiost/37/2/424.full.pdf

المؤلفون: Christopher G. Knight, Mark Platt, William Rowe, David C. Wedge, Farid Khan, Philip J. R. Day, Andy Mcshea, Joshua Knowles, Douglas B. Kell

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://nar.oxfordjournals.org/content/37/1/e6.full-text-lowres.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.331.3677; http://nar.oxfordjournals.org/content/37/1/e6.full-text-lowres.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.331.3677
http://nar.oxfordjournals.org/content/37/1/e6.full-text-lowres.pdf

المؤلفون: Philip J. R. Day, Avinash D. Ghanate, Fiona Marriage, Selva Rupa Christinal Immanuel, Dharmeshkumar S. Parmar, Venkateswarlu Panchagnula, Anu Raghunathan

المصدر: Biochemical and Biophysical Research Communications. 495:2010-2016

مصطلحات موضوعية: 0301 basic medicine, Cell Survival, Population, Biophysics, Biochemistry, Serine, 03 medical and health sciences, Cell Line, Tumor, Pyruvic Acid, Temozolomide, Humans, Proline, Amino Acids, education, Antineoplastic Agents, Alkylating, Molecular Biology, Alanine, education.field_of_study, Dose-Response Relationship, Drug, Chemistry, Cell Biology, Metabolism, Cell sorting, Metabolic Flux Analysis, Dacarbazine, Systems Integration, Glutamine, Glucose, 030104 developmental biology, DNA methylation, Glioblastoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52eac094d29abd6ec5a5dd32e70d3e63
https://doi.org/10.1016/j.bbrc.2017.12.073

المؤلفون: Steve O'Hagan, Farah Mughal, Marina Wright Muelas, Philip J. R. Day, Douglas B. Kell

المصدر: Scientific Reports
Wright Muelas, M, Mughal, F, O’Hagan, S, Day, P J & Kell, D B 2019, ' The role and robustness of the Gini coefficient as an unbiased tool for the selection of Gini genes for normalising expression profiling data ', Scientific Reports, vol. 9, no. 1, 17960 . https://doi.org/10.1038/s41598-019-54288-7
Scientific Reports, Vol 9, Iss 1, Pp 1-21 (2019)
Wright Muelas, M, Mughal, F, O’Hagan, S, Day, P J & Kell, D 2019, ' The role and robustness of the Gini coefficient as an unbiased tool for the selection of Gini genes for normalising expression profiling data ', Scientific Reports, vol. 9, no. 1, 17960 . https://doi.org/10.1038/s41598-019-54288-7

مصطلحات موضوعية: Cell biology, lcsh:Medicine, Gene Expression, Computational biology, Biology, Article, Cell Line, 03 medical and health sciences, 0302 clinical medicine, Reference genes, Gene expression, Humans, lcsh:Science, Transcriptomics, Gene, Selection (genetic algorithm), 030304 developmental biology, 0303 health sciences, Multidisciplinary, Genes, Essential, Gini coefficient, Gene Expression Profiling, lcsh:R, Robustness (evolution), Reference Standards, Housekeeping gene, Computational biology and bioinformatics, Gene expression profiling, 030220 oncology & carcinogenesis, lcsh:Q, Transcriptome, Algorithms

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f16b8b6370cbf5fd993e1ef18a065c
http://europepmc.org/articles/PMC6884504

المؤلفون: Douglas B. Kell, Srijan Jindal, Lei Yang, Philip J. R. Day

المصدر: BMC Microbiology, Vol 19, Iss 1, Pp 1-16 (2019)
BMC Microbiology
Jindal, S, Yang, L, Day, P & Kell, D 2019, ' Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli ', B M C Microbiology . https://doi.org/10.1186/s12866-019-1561-0
Jindal, S, Yang, L, Day, P J & Kell, D B 2019, ' Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli ', BMC Microbiology, vol. 19, no. 1, 195 . https://doi.org/10.1186/s12866-019-1561-0
BMC MICROBIOLOGY

مصطلحات موضوعية: Microbiology (medical), lcsh:QR1-502, drug transporters, Carbocyanine, Diamines, medicine.disease_cause, Microbiology, lcsh:Microbiology, Flow cytometry, 03 medical and health sciences, chemistry.chemical_compound, Drug transporters, Escherichia coli, medicine, SYBR Green, Benzothiazoles, Organic Chemicals, Lipid bilayer, Keio, Gene knockout, Fluorescent Dyes, 030304 developmental biology, Membrane potential, carbocyanine, 0303 health sciences, medicine.diagnostic_test, ATP synthase, biology, 030306 microbiology, Escherichia coli Proteins, Membrane energisation, Wild type, Membrane Transport Proteins, Biological Transport, membrane energisation, Transporter, Carbocyanines, Flow Cytometry, chemistry, Biochemistry, Quinolines, biology.protein, DNA, Research Article

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5831a6b9d60562f77a845cf3cbe9861
https://doi.org/10.1101/603688

المؤلفون: Doi:j. Clin Microbiol, Christoph M. Tang, David Nadal, Oliver Greiner, Christoph Berger, Philip J. R. Day

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://jcm.asm.org/content/40/11/3917.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.621.5978; http://jcm.asm.org/content/40/11/3917.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.621.5978
http://jcm.asm.org/content/40/11/3917.full.pdf

المؤلفون: Alistair Revell, Philip J. R. Day, Joseph O’Connor, Parthasarathi Mandal

المصدر: O'Connor, J, Day, P, Mandal, P & Revell, A 2016, ' Computational fluid dynamics in the microcirculation and microfluidics : What role can the lattice Boltzmann method play? ', Integrative Biology, vol. 8, no. 5, pp. 589-602 . https://doi.org/10.1039/c6ib00009f

مصطلحات موضوعية: Computer science, Microfluidics, 0206 medical engineering, Biophysics, Lattice Boltzmann methods, 02 engineering and technology, Computational fluid dynamics, Bioinformatics, Biochemistry, Fluid dynamics, Animals, Humans, Computer Simulation, Parametric statistics, Weight measurement scales, business.industry, Microcirculation, Scale (chemistry), Models, Cardiovascular, 021001 nanoscience & nanotechnology, 020601 biomedical engineering, Microvessels, Biochemical engineering, Rheology, 0210 nano-technology, business, Blood Flow Velocity

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cec745062126ad50b486c49c7dbf212
https://doi.org/10.1039/c6ib00009f

المؤلفون: Philip J. R. Day, Srijan Jindal, Harish Thampy, Douglas B. Kell

المصدر: Microbiology
Jindal, S, Thampy, H, Day, P & Kell, D 2019, ' Very rapid flow cytometric assessment of antimicrobial susceptibility during the apparent lag phase of microbial (re)growth ', Microbiology . https://doi.org/10.1099/mic.0.000777

مصطلحات موضوعية: Bacteriuria, medicine.drug_class, Lag, Antibiotics, Antimicrobial susceptibility, Microbial Sensitivity Tests, Microbiology, Flow cytometry, 03 medical and health sciences, Antibiotic resistance, Phase (matter), medicine, Humans, 030304 developmental biology, Dna distribution, 0303 health sciences, medicine.diagnostic_test, Bacteria, 030306 microbiology, Chemistry, medicine.disease, Flow Cytometry, Anti-Bacterial Agents, Culture Media, Stationary phase, Urinary Tract Infections, Biophysics

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cce160c825bced7d23839a106969cf
https://pubmed.ncbi.nlm.nih.gov/30741628

المؤلفون: J.E. Parkes, Hector Chinoy, Philip J. R. Day, Janine A. Lamb

المصدر: THURSDAY, 14 JUNE 2018.

مصطلحات موضوعية: Messenger RNA, Downregulation and upregulation, business.industry, microRNA, Gene expression, medicine, Cancer research, RNA, Inclusion body myositis, medicine.disease, business, Polymyositis, Myositis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4f20beb72f5c4959906dd4aa0a304af1
https://doi.org/10.1136/annrheumdis-2018-eular.5593

المؤلفون: Duncan Ayers, Philip J. R. Day

المصدر: Molecular Biology International

مصطلحات موضوعية: Computer science, Applied Mathematics, General Mathematics, Systems biology, Health condition, MEDLINE, Review Article, Disease, Medical research, Bioinformatics, Systems medicine, Drug development, Risk analysis (engineering), Molecular targets

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d49583af42293e6bf875500fb091ee
https://doi.org/10.1155/2015/698169