المؤلفون: Stefanie Hoffmann, Philip Hewitt, Isabel Koscielski, Dorota Kurek, Wouter Strijker, Kinga Kosim

المصدر: Frontiers in Drug Discovery, Vol 4 (2025)

مصطلحات موضوعية: OrganoTEER, organ-on-chips, in vitro barrier model, drug toxicity, CaCo-2, preclinical safety, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fddsv.2024.1459424/full; https://doaj.org/toc/2674-0338

URL الوصول: https://doaj.org/article/e18a72986b3341f597202a83d052a7b3

المؤلفون: Luise A. Roser, Christina Sakellariou, Malin Lindstedt, Vanessa Neuhaus, Susann Dehmel, Charline Sommer, Martin Raasch, Thierry Flandre, Sigrid Roesener, Philip Hewitt, Michael J. Parnham, Katherina Sewald, Susanne Schiffmann

المصدر: Journal of Immunotoxicology, Vol 21, Iss sup1, Pp S60-S78 (2024)

مصطلحات موضوعية: Adverse outcome pathway, adverse event, drug-induced liver injury, immune safety, immunotherapy, interleukin-2, Immunologic diseases. Allergy, RC581-607, Toxicology. Poisons, RA1190-1270

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1547-691X; https://doaj.org/toc/1547-6901

URL الوصول: https://doaj.org/article/a931852d8d8840f494aa1daaaca9c913

المؤلفون: Luisa Marie Pfeifer, Janike Sensbach, Frederic Pipp, Daniela Werkmann, Philip Hewitt

المصدر: Frontiers in Toxicology, Vol 6 (2024)

مصطلحات موضوعية: serum-free, in vitro toxicology, sustainability, animal welfare, HepG2, Toxicology. Poisons, RA1190-1270

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/ftox.2024.1439031/full; https://doaj.org/toc/2673-3080

URL الوصول: https://doaj.org/article/9a8e25f54f6e4a35bc69b0d1d5f20608

المؤلفون: Luise A. Roser, Sonja Luckhardt, Nicole Ziegler, Dominique Thomas, Pia Viktoria Wagner, Georg Damm, Andrea Scheffschick, Philip Hewitt, Michael J. Parnham, Susanne Schiffmann

المصدر: Frontiers in Immunology, Vol 14 (2023)

مصطلحات موضوعية: immune-related adverse events, immunotherapy, in vitro prognostics, triple-culture model, immune cells, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1275368/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/d8986d43e74648aabbcdae2dbf5bc4f8

المؤلفون: Alicia Y. Lim, Yuki Kato, Courtney Sakolish, Alan Valdiviezo, Gang Han, Piyush Bajaj, Jason Stanko, Stephen S. Ferguson, Remi Villenave, Philip Hewitt, Rhiannon N. Hardwick, Ivan Rusyn

المصدر: Bioengineering, Vol 10, Iss 10, p 1195 (2023)

مصطلحات موضوعية: microphysiological systems, liver, testing, tissue chip, Technology, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2306-5354/10/10/1195; https://doaj.org/toc/2306-5354

URL الوصول: https://doaj.org/article/a18304e2256b45029ba33d462bd66feb

المؤلفون: Luise A. Roser, Sonja Luckhardt, Nicole Ziegler, Dominique Thomas, Pia Viktoria Wagner, Georg Damm, Andrea Scheffschick, Philip Hewitt, Michael J. Parnham, Susanne Schiffmann

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, immune-related adverse events, immunotherapy, in vitro prognostics, triple-culture model, immune cells

Relation: https://figshare.com/articles/presentation/Presentation_1_Immuno-inflammatory_in_vitro_hepatotoxicity_models_to_assess_side_effects_of_biologicals_exemplified_by_aldesleukin_pdf/24579781

الاتاحة: https://doi.org/10.3389/fimmu.2023.1275368.s001
https://figshare.com/articles/presentation/Presentation_1_Immuno-inflammatory_in_vitro_hepatotoxicity_models_to_assess_side_effects_of_biologicals_exemplified_by_aldesleukin_pdf/24579781

المؤلفون: Valeria Chichagova, Maria Georgiou, Madeleine Carter, Birthe Dorgau, Gerrit Hilgen, Joseph Collin, Rachel Queen, Git Chung, Jila Ajeian, Marina Moya‐Molina, Stefan Kustermann, Francois Pognan, Philip Hewitt, Michael Schmitt, Evelyne Sernagor, Lyle Armstrong, Majlinda Lako

المصدر: Journal of Cellular and Molecular Medicine. 27:435-445

مصطلحات موضوعية: Molecular Medicine, Cell Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e355d2946cbd046ef929311d3cdfb0b9
https://doi.org/10.1111/jcmm.17670

المؤلفون: Ivan Rusyn, Courtney Sakolish, Yuki Kato, Clifford Stephan, Leoncio Vergara, Philip Hewitt, Vasanthi Bhaskaran, Myrtle Davis, Rhiannon N Hardwick, Stephen S Ferguson, Jason P Stanko, Piyush Bajaj, Karissa Adkins, Nisha S Sipes, E Sidney Hunter, Maria T Baltazar, Paul L Carmichael, Kritika Sadh, Richard A Becker

المصدر: Toxicol Sci

مصطلحات موضوعية: Lab-On-A-Chip Devices, Humans, In-Depth Reviews, Toxicology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5fe00b5247331ff1b276233e30fd420
https://pubmed.ncbi.nlm.nih.gov/35689632

المؤلفون: Anna Borgström, Bruno Guy Henri Filippi, Philip Hewitt, Armin Wolf, Mathias Gebauer

المصدر: Applied In Vitro Toxicology.

مصطلحات موضوعية: Medical Laboratory Technology, Health, Toxicology and Mutagenesis, Toxicology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d391e7f6758631ab0356a744ae81cab9
https://doi.org/10.1089/aivt.2023.0004

المؤلفون: Dean Hallam, Gerrit Hilgen, Birthe Dorgau, Lili Zhu, Min Yu, Sanja Bojic, Philip Hewitt, Michael Schmitt, Marianne Uteng, Stefan Kustermann, David Steel, Mike Nicholds, Rob Thomas, Achim Treumann, Andrew Porter, Evelyne Sernagor, Lyle Armstrong, Majlinda Lako

مصطلحات موضوعية: Mechanical Engineering not elsewhere classified, untagged

Relation: 2134/34320; https://figshare.com/articles/journal_contribution/Human_induced_pluripotent_stem_cells_generate_light_responsive_retinal_organoids_with_variable_and_nutrient_dependent_efficiency_/9561170

الاتاحة: https://figshare.com/articles/journal_contribution/Human_induced_pluripotent_stem_cells_generate_light_responsive_retinal_organoids_with_variable_and_nutrient_dependent_efficiency_/9561170

المؤلفون: Felix Rohdich, Stefano Crosignani, Michael Busch, Christina Esdar, Manja Friese-Hamim, Markus Klein, Thomas Fuchss, Oliver Schadt, Djordje Musil, Ugo Zanelli, Michael P. Sanderson, Gina Walter-Bausch, Philip Hewitt, Jeyaprakashnarayanan Seenisamy

المصدر: Journal of Medicinal Chemistry. 64:10230-10245

مصطلحات موضوعية: Gene isoform, Proteasome Endopeptidase Complex, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Protein subunit, Protein degradation, medicine.disease, Protein Subunits, Structure-Activity Relationship, Haematopoiesis, Proteasome, Biochemistry, Drug Discovery, medicine, Humans, Molecular Medicine, Potency, Structure based, Proteasome Inhibitors, Multiple myeloma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a3d051fc60306aef1b64a7ba1b3e7b
https://doi.org/10.1021/acs.jmedchem.1c00604

المؤلفون: Franck A. Atienzar, Eric A. Blomme, Minjun Chen, Philip Hewitt, J. Gerry Kenna, Gilles Labbe, Frederic Moulin, Francois Pognan, Adrian B. Roth, Laura Suter-Dick, Okechukwu Ukairo, Richard J. Weaver, Yvonne Will, Donna M. Dambach

المصدر: BioMed Research International, Vol 2016 (2016)

مصطلحات موضوعية: Medicine

Relation: http://dx.doi.org/10.1155/2016/9737920; https://doaj.org/toc/2314-6133; https://doaj.org/toc/2314-6141; https://doaj.org/article/50f0abf09f6a42c4bc87218dda0b0e1a

الاتاحة: https://doi.org/10.1155/2016/9737920
https://doaj.org/article/50f0abf09f6a42c4bc87218dda0b0e1a

المؤلفون: Philip Hewitt, Nada Abla, Floriane Lignet, Claude Oeuvray, Wilhelmina Bagchus, Lidiya Bebrevska

المصدر: Toxicology and applied pharmacology. 443

مصطلحات موضوعية: Pharmacology, Antimalarials, No-Observed-Adverse-Effect Level, Plasmodium, Dogs, Peptide Elongation Factor 2, Research Design, Animals, Toxicology, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f65d8383d14e151dc7cfc2ee0787f1
https://pubmed.ncbi.nlm.nih.gov/35367236

المؤلفون: Yuki, Kato, Alicia Y, Lim, Courtney, Sakolish, Alan, Valdiviezo, Haley L, Moyer, Philip, Hewitt, Piyush, Bajaj, Gang, Han, Ivan, Rusyn

المصدر: Toxicology in Vitro. 85:105464

مصطلحات موضوعية: Myristates, Reproducibility of Results, Endothelial Cells, General Medicine, Acetates, Toxicology, Phorbols, Culture Media, Liver, Albumins, Hepatocytes, Humans, Cytochrome P-450 CYP3A, Urea, Cells, Cultured

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55bfa095fa212bdcd71f7cb7c781c2fa
https://doi.org/10.1016/j.tiv.2022.105464

المؤلفون: Yvonne Will, Philip Hewitt, Hartmut Jaeschke, Hilmi Orhan, Mathieu Vinken, Kendall B. Wallace

المساهمون: Liver Connexin and Pannexin Research Group, Pharmaceutical and Pharmacological Sciences, Connexin Signalling Research Group, Experimental in vitro toxicology and dermato-cosmetology

المصدر: Applied In Vitro Toxicology. 5:167-172

مصطلحات موضوعية: Medical Laboratory Technology, Mitochondrial toxicity, Health, Toxicology and Mutagenesis, medicine, Pharmacology, Biology, Toxicology, medicine.disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d56f70206754245ddb12c0b59630062f
https://doi.org/10.1089/aivt.2019.29022.rtl

المؤلفون: Birthe Dorgau, Maria Georgiou, Alexander Chaudhary, Marina Moya-Molina, Joseph Collin, Rachel Queen, Gerrit Hilgen, Tracey Davey, Philip Hewitt, Michael Schmitt, Stefan Kustermann, Francois Pognan, David H Steel, Evelyne Sernagor, Lyle Armstrong, Majlinda Lako

المصدر: Stem cells translational medicine. 11(2)

مصطلحات موضوعية: Organoids, Digoxin, Thioridazine, Induced Pluripotent Stem Cells, Humans, B200, Cell Differentiation, Cell Biology, General Medicine, B500, Retina, Sildenafil Citrate, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d8707825646a15d2f751018015a358
https://pubmed.ncbi.nlm.nih.gov/35298655

المؤلفون: F. Pognan, L. Armstrong, G. Hilgen, M. Lako, Git Chung, J. Ajeian, Philip Hewitt, V. Chichagova, J. Collin, R. Queen, B. Dorgau, M. Georgiou, M Carter, M Schmitt, C. de Santis, Stefan Kustermann, Marina Moya-Molina, E. Sernagor

المصدر: Toxicology Letters. 350:S45

مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Toxicity, Organoid, Cancer research, Retinal, General Medicine, Biology, Toxicology, In vitro

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::18203785d49ed5656d20647c3936be67
https://doi.org/10.1016/s0378-4274(21)00355-6

المؤلفون: Julia Hoeng, Joëlle Rüegg, Costanza Rovida, Matthias Herzler, Sofia B. Leite, Barry Hardy, Thomas Steger-Hartmann, Sandra Coecke, Francois Busquet, Thomas Exner, Barbara M.A. van Vugt-Lussenburg, Mirjam Luijten, Janine Ezendam, Jan G. Hengstler, Florian Gantner, Tanja Waldmann, Susanne Hougaard Bennekou, Kristina Fant, Bart van der Burg, Alice Krebs, Marcel Leist, Daniel R. Dietrich, Albert Braeuning, Ellen Fritsche, Emma Pedersen, Giorgia Pallocca, Tuula Heinonen, Mario Beilmann, Andrea Terron, Philip Hewitt, Thomas Hartung, Olesja Bondarenko, Stefan Kustermann, Hennicke Kamp, Torsten R. Dunkern, Martin F. Wilks

المصدر: Krebs, A, Waldmann, T, Wilks, M F, Van Vugt-Lussenburg, B M A, Van der Burg, B, Terron, A, Steger-Hartmann, T, Ruegg, J, Rovida, C, Pedersen, E, Pallocca, G, Luijten, M, Leite, S B, Kustermann, S, Kamp, H, Hoeng, J, Hewitt, P, Herzler, M, Hengstler, J G, Heinonen, T, Hartung, T, Hardy, B, Gantner, F, Fritsche, E, Fant, K, Ezendam, J, Exner, T, Dunkern, T, Dietrich, D R, Coecke, S, Busquet, F, Braeuning, A, Bondarenko, O, Hougaard Bennekou, S, Beilmann, M & Leist, M 2020, ' Erratum to Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data ', A L T E X. Alternatives to Animal Experimentation, vol. 37, no. 1, pp. 164-164 . https://doi.org/10.14573/altex.1909271e

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Research design, Computer science, Level of detail (writing), General Medicine, Test method, Test (assessment), law.invention, 03 medical and health sciences, Medical Laboratory Technology, 030104 developmental biology, 0302 clinical medicine, Documentation, Risk analysis (engineering), Acceptance testing, law, CLARITY, Relevance (information retrieval), 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17547a120d82232053cfcea5a885530
https://orbit.dtu.dk/en/publications/07a9a3c2-fd15-408a-a12a-cade067fb4c2

المؤلفون: Adrian Roth, Douglas A. Keller, Philip Hewitt, Andreas Baudy, Terry R. Van Vleet, Radhakrishna Sura, Monicah A. Otieno, Jinping Gan, William R Proctor

المصدر: Lab on a chip. 20(2)

مصطلحات موضوعية: Drug Industry, Process (engineering), Computer science, Biomedical Engineering, Drug Evaluation, Preclinical, Bioengineering, Biochemistry, Risk Assessment, 03 medical and health sciences, 0302 clinical medicine, Lab-On-A-Chip Devices, Animals, Humans, Animal testing, 030304 developmental biology, Pharmaceutical industry, 0303 health sciences, System development, business.industry, End user, General Chemistry, Drug development, Risk analysis (engineering), Safety risk, Liver, Pharmaceutical Preparations, 030220 oncology & carcinogenesis, Risk assessment, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad20b0de1b57f15d2012f4870b6fafb
https://pubmed.ncbi.nlm.nih.gov/31799979

المؤلفون: Philip Hewitt, PONS Langenscheidt GmbH

Resource Type: eBook.

Categories: LANGUAGE STUDY / English as a Second Language, EDUCATION / General