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1Academic JournalT-bet and Eomes Are Differentially Linked to the Exhausted Phenotype of CD8+T Cells in HIV Infection
المؤلفون: Buggert, Marcus, Tauriainen, Johanna, Yamamoto, Takuya, Frederiksen, Juliet Wairimu, Ivarsson, Martin A., Michaelsson, Jakob, Lund, Ole, Hejdeman, Bo, Jansson, Marianne, Sonnerborg, Anders, Koup, Richard A., Betts, Michael R., Karlsson, Annika C.
المصدر: Buggert , M , Tauriainen , J , Yamamoto , T , Frederiksen , J W , Ivarsson , M A , Michaelsson , J , Lund , O , Hejdeman , B , Jansson , M , Sonnerborg , A , Koup , R A , Betts , M R & Karlsson , A C 2014 , ' T-bet and Eomes Are Differentially Linked to the Exhausted Phenotype of CD8+T Cells in HIV Infection ' , P L o S Pathogens , vol. 10 , no. 7 , e1004251 . https://doi.org/10.1371/journal.ppat.1004251
مصطلحات موضوعية: DNA and RNA Reverse Transcribing Viruses Viruses Microorganisms (DNA and RNA Reverse Transcribing Viruses, Microorganisms, Viruses) - Retroviridae [03305] HIV common Human immunodeficiency virus species pathogen, Primates Mammalia Vertebrata Chordata Animalia (Animals, Chordates, Humans, Mammals, Primates, Vertebrates) - Hominidae [86215] human common adult, middle age host female, male, 2B4, CD160, Eomes expression, inhibitory receptors, PD-1, T-bet expression, transcription factors, Cytology - Animal, Cytology - Human, Biochemistry studies - General, Pathology - Therapy, Pharmacology - General, Pharmacology - Clinical pharmacology
Time: 02506, 02508, 10060, 12512, 22002, 22005, 33502, 34502, 34508, 36006
وصف الملف: application/pdf
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2Academic Journal
المؤلفون: Hansen, Anders N., Bendiksen, Christine D., Sylvest, Lene, Friis, Tina, Staerk, Dan, Jorgensen, Flemming Steen, Olsen, Christian A., Houen, Gunnar
المصدر: Hansen , A N , Bendiksen , C D , Sylvest , L , Friis , T , Staerk , D , Jorgensen , F S , Olsen , C A & Houen , G 2012 , ' Synthesis and Antiangiogenic Activity of N-Alkylated Levamisole Derivatives ' , P L o S One , vol. 7 , no. 9 , pp. Article No.: e45405 . https://doi.org/10.1371/journal.pone.0045405
مصطلحات موضوعية: cell morphology, structure-activity relationship, tumor Neoplasms (MeSH) neoplastic disease drug therapy, Primates Mammalia Vertebrata Chordata Animalia (Animals, Chordates, Humans, Mammals, Primates, Vertebrates) - Hominidae [86215] HUVEC cell line cell_line human umbilical vein endothelial cells NHDF cell line cell_line normal human dermal fibroblast cells, (S)-levamisole hydrochloride antineoplastic-drug synthesis efficacy, N-methyllevamisole antineoplastic-drug synthesis efficacy, para-bromolevamisole antineoplastic-drug synthesis efficacy, suramin 145-63-1 antineoplastic-drug efficacy, Cytology - Human, Biochemistry studies - General, Pathology - Therapy, Pharmacology - General, Pharmacology - Clinical pharmacology, Neoplasms - Pathology, clinical aspects and systemic effects, Neoplasms - Therapeutic agents and therapy, Tissue culture
Time: 02508, 10060, 12512, 22002, 22005, 24004, 24008, 32500
وصف الملف: application/pdf
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3Academic Journal
المؤلفون: So, Jonathan, Pasculescu, Adrian, Dai, Anna Y., Williton, Kelly, James, Andrew, Nguyen, Vivian, Creixell, Pau, Schoof, Erwin M., Sinclair, John, Barrios-Rodiles, Miriam, Gu, Jun, Krizus, Aldis, Williams, Ryan, Olhovsky, Marina, Dennis, James W., Wrana, Jeffrey L., Linding, Rune, Jørgensen, Claus, Pawson, Tony, Colwill, Karen
المصدر: So , J , Pasculescu , A , Dai , A Y , Williton , K , James , A , Nguyen , V , Creixell , P , Schoof , E M , Sinclair , J , Barrios-Rodiles , M , Gu , J , Krizus , A , Williams , R , Olhovsky , M , Dennis , J W , Wrana , J L , Linding , R , Jørgensen , C , Pawson , T & Colwill , K 2015 , ' Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential ....
مصطلحات موضوعية: apoptosis, cancer Neoplasms (MeSH) neoplastic disease, Primates Mammalia Vertebrata Chordata Animalia (Animals, Chordates, Humans, Mammals, Primates, Vertebrates) - Hominidae [86215] DLD-1 cell line cell_line human colon adenocarcinoma cells, AAK1, cDNA complementary DNA expression, protein kinase 372092-80-3 EC 2.7.13.3, PXK, TRAIL receptor, TRAIL signaling, Cytology - Human, Biochemistry studies - General, Biochemistry studies - Nucleic acids, purines and pyrimidines, Enzymes - General and comparative studies: coenzymes, Pathology - Therapy, Pharmacology - General, Pharmacology - Clinical pharmacology
Time: 02508, 10060, 10062, 10802, 12512, 22002, 22005, 24004
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4Academic Journal
المؤلفون: Shi, Leming, Haibe-Kains, Benjamin, Birkbak, Nicolai Juul, Bedard, Philippe L., Hatzis, Christos, Stern, David F., Clarke, Robert, Quackenbush, John, Beck, Andrew H., Aerts, Hugo J. W. L.
المصدر: Shi , L , Haibe-Kains , B , Birkbak , N J , Bedard , P L , Hatzis , C , Stern , D F , Clarke , R , Quackenbush , J , Beck , A H & Aerts , H J W L 2014 , ' Enhancing Reproducibility in Cancer Drug Screening: How Do We Move Forward? ' , Cancer Research , vol. 74 , no. 15 , pp. 4016-4023 . https://doi.org/10.1158/0008-5472.CAN-14-0725
مصطلحات موضوعية: drug response phenotype, drug sensitivity, genome, Primates Mammalia Vertebrata Chordata Animalia (Animals, Chordates, Humans, Mammals, Primates, Vertebrates) - Hominidae [86215] human common, biomarker, Biochemistry studies - Nucleic acids, purines and pyrimidines, Pathology - Therapy, Pharmacology - General, Pharmacology - Clinical pharmacology, Neoplasms - Pathology, clinical aspects and systemic effects, cancer drug screening laboratory techniques, large-scale pharmacogenomic high-throughput screening laboratory techniques, Methods and Techniques, Pharmacology, Tumor Biology, ONCOLOGY, MICROARRAY DATA, CYTOTOXICITY
Time: 10062, 12512, 22002, 22005, 24004
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5Academic Journal
المؤلفون: Sims-Williams, H P, Matthews, J C, Javed, S, Love-Jones, S J, Talbot, P S, Patel, N K, Pickering, A E
المصدر: Sims-Williams , H P , Matthews , J C , Javed , S , Love-Jones , S J , Talbot , P S , Patel , N K & Pickering , A E 2013 , Does Deep brain stimulation of the peri-aqueductal gray release endogenous opioids? A [C-11]diprenorphine PET imaging study . in host publication . vol. 43 , Society for Neuroscience Abstract Viewer and Itinerary Planner , 1/01/24 .
مصطلحات موضوعية: General biology - Symposia, transactions and proceedings, Anatomy and Histology - Surgery, Pathology - Diagnostic, Pathology - Therapy, Blood, Blood - Blood cell studies, Nervous system -, Pharmacology - Clinical pharmacology, Primates, Mammalia, Vertebrata, Chordata, Animalia, Animals, Chordates, Humans, Mammals, Vertebrates, techniques, diagnostic techniques
Time: 00520, 11105, 12504, 12512, 15002, 15004, 20506, 22005
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6
المؤلفون: Sarah M. Tindall, Karen Swift, Simon V. Avery, Kevin C. F. Fone, Farida Hanim Islahudin, Kang Nee Ting, Richard J. Pleass, Ian R. Mellor, Hans Erik Mølager Christensen
المصدر: Islahudin, F, Tindall, S M, Mellor, I R, Swift, K, Christensen, H E M, Fone, K C F, Pleass, R J, Ting, K-N & Avery, S V 2014, ' The antimalarial drug quinine interferes with serotonin biosynthesis and action ', Scientific Reports, vol. 4, 3618 . https://doi.org/10.1038/srep03618
Scientific Reportsمصطلحات موضوعية: Kynurenine pathway, 60504, Parasitology - Medical, plasma blood and lymphatics, 10060, Biochemistry studies - General, Tryptophan Hydroxylase, Pharmacology, Fungi Plantae (Fungi, Microorganisms, Nonvascular Plants, Plants) - Ascomycetes [15100] Saccharomyces cerevisiae species, Neuroblastoma, chemistry.chemical_compound, FALCIPARUM-MALARIA, qv_257, qv_256, BRAIN, Neurotransmitter, 15002, Blood - Blood and lymph studies, Quinine, 22002, Pharmacology - General, 36008, Medical and clinical microbiology - Mycology, Multidisciplinary, TRYPTOPHAN-HYDROXYLASE, TPH2, PLASMA, 38510, Chemotherapy - Antiparasitic agents, PROLIFERATION, 38502, Chemotherapy - General, methods and metabolism, Hematology, 12512, Pathology - Therapy, 15006, Blood - Blood, lymphatic and reticuloendothelial pathologies, 60502, Parasitology - General, 15004, Blood - Blood cell studies, RECEPTORS, qv_126, Biochemistry, Serotonin Production, DEPLETION, drug development, enzyme mechanisms, malaria, mechanism of action, BEHAVIOR, medicine.drug, Serotonin, quinine 130-95-0 antiinfective-drug, antiparasitic-drug, Fungi Plantae (Fungi, Microorganisms, Nonvascular Plants, Plants) - Fungi Imperfecti or Deuteromycetes [15500] Candida albicans species, INHIBITION, neurotransmitter serotonin-5 5-HT receptor synthesis, Saccharomyces cerevisiae, Biology, Human Medicine, Medical Sciences, qv_38, 22005, Pharmacology - Clinical pharmacology, Article, Antimalarials, KYNURENINE PATHWAY, SDG 3 - Good Health and Well-being, Cell Line, Tumor, medicine, Humans, tryptophan 73-22-3, Primates Mammalia Vertebrata Chordata Animalia (Animals, Chordates, Humans, Mammals, Primates, Vertebrates) - Hominidae [86215] SHSY5Y cell line cell_line human neuroblastoma cells, 10064, Biochemistry studies - Proteins, peptides and amino acids, Tryptophan, Tryptophan hydroxylase, wc_750, chemistry, 02508, Cytology - Human, Parasitology, malaria Malaria (MeSH) blood and lymphatic disease, parasitic disease drug therapy, symptom, MULTIDISCIPLINARY, tryptophan hydroxylase TPH2 9037-21-2 EC 1.14.16.4
وصف الملف: application/pdf; PDF
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7Review
المؤلفون: Lader, M.J.
المصدر: British Medical Journal. 2/10/1979, Vol. 1 Issue 6160, p401-402. 2p.
مصطلحات موضوعية: *PHARMACOLOGY, *NONFICTION
Reviews & Products: MONOGRAPHS in Clinical Pharmacology: Clinical Pharmacology of Psychotherapeutic Drugs (Book)
People: HOLLISTER, Leo E.
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8Academic Journal
المؤلفون: Mitrofanov, I.1 mitrofanov@np.cosmos.ru
المصدر: Astronomy Reports. Apr2017, Vol. 61 Issue 4, p324-331. 8p.
مصطلحات موضوعية: *EXTRATERRESTRIAL life, *SOLAR system, *SPACE exploration
Reviews & Products: MONOGRAPHS in Clinical Pharmacology: Clinical Pharmacology of Psychotherapeutic Drugs (Book)
People: SHKLOVSKII, I. S., 1916-1985
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9Electronic Resource
المؤلفون: Islahudin, Farida, Tindall, Sarah M., Mellor, Ian R., Swift, Karen, Christensen, Hans Erik Mølager, Fone, Kevin C. F., Pleass, Richard J., Ting, Kang-Nee, Avery, Simon V.
المصدر: Islahudin , F , Tindall , S M , Mellor , I R , Swift , K , Christensen , H E M , Fone , K C F , Pleass , R J , Ting , K-N & Avery , S V 2014 , ' The antimalarial drug quinine interferes with serotonin biosynthesis and action ' , Scientific Reports , vol. 4 , 3618 .
مصطلحات الفهرس: MULTIDISCIPLINARY, TRYPTOPHAN-HYDROXYLASE, KYNURENINE PATHWAY, FALCIPARUM-MALARIA, RECEPTORS, BRAIN, DEPLETION, BEHAVIOR, PROLIFERATION, INHIBITION, PLASMA, malaria Malaria (MeSH) blood and lymphatic disease, parasitic disease drug therapy, symptom, Fungi Plantae (Fungi, Microorganisms, Nonvascular Plants, Plants) - Ascomycetes [15100] Saccharomyces cerevisiae species, Fungi Plantae (Fungi, Microorganisms, Nonvascular Plants, Plants) - Fungi Imperfecti or Deuteromycetes [15500] Candida albicans species, Primates Mammalia Vertebrata Chordata Animalia (Animals, Chordates, Humans, Mammals, Primates, Vertebrates) - Hominidae [86215] SHSY5Y cell line cell_line human neuroblastoma cells, neurotransmitter serotonin-5 5-HT receptor synthesis, quinine 130-95-0 antiinfective-drug, antiparasitic-drug, tryptophan 73-22-3, tryptophan hydroxylase TPH2 9037-21-2 EC 1.14.16.4, 02508, Cytology - Human, 10060, Biochemistry studies - General, 10064, Biochemistry studies - Proteins, peptides and amino acids, 12512, Pathology - Therapy, 15002, Blood - Blood and lymph studies, 15004, Blood - Blood cell studies, 15006, Blood - Blood, lymphatic and reticuloendothelial pathologies, 22002, Pharmacology - General, 22005, Pharmacology - Clinical pharmacology, 36008, Medical and clinical microbiology - Mycology, 38502, Chemotherapy - General, methods and metabolism, 38510, Chemotherapy - Antiparasitic agents, 60502, Parasitology - General, 60504, Parasitology - Medical, Human Medicine, Medical Sciences, plasma blood and lymphatics, Hematology, Parasitology, Pharmacology, dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being; name=SDG 3 - Good Health and Well-being, article