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1Conference
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2
المؤلفون: Jieru Meng, Vassiliki A. Papadimitrakopoulou, Duoli Sun, Bingliang Fang, Jack A. Roth, Roy S. Herbst, B. Nebiyou Bekele, John D. Minna, Michael Peyton, Zhenghong Peng, Bingbing Dai, William G. Bornmann
المصدر: PLoS ONE
PLoS ONE, Vol 5, Iss 11, p e14124 (2010)مصطلحات موضوعية: Lung Neoplasms, Combination therapy, Colorectal cancer, Cell Survival, lcsh:Medicine, Mice, Nude, Apoptosis, Pharmacology, chemistry.chemical_compound, Mice, In vivo, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, Medicine, Animals, Humans, Lung cancer, lcsh:Science, Protein kinase B, Oncology/Lung Cancer, Mitogen-Activated Protein Kinase Kinases, Mice, Inbred BALB C, Multidisciplinary, Dose-Response Relationship, Drug, business.industry, lcsh:R, Cell Cycle, Drug Synergism, Cell cycle, Pharmacology/Drug Resistance, medicine.disease, Survival Analysis, Xenograft Model Antitumor Assays, Tumor Burden, chemistry, MK-2206, lcsh:Q, Benzimidazoles, Female, business, Pharmacology/Personalized Medicine, Heterocyclic Compounds, 3-Ring, Proto-Oncogene Proteins c-akt, Research Article, Signal Transduction
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3
المؤلفون: Andrea Pirzkall, Elizabeth Punnoose, Bernard M. Fine, Daniel S. Chen, Mark R. Lackner, Ajay Pandita, Lukas C. Amler, Heidi Savage, Siminder K. Atwal, Jill M. Spoerke, Ru-Fang Yeh
المصدر: PLoS ONE
PLoS ONE, Vol 5, Iss 9, p e12517 (2010)مصطلحات موضوعية: Male, Pathology, medicine.medical_specialty, Lung Neoplasms, Receptor, ErbB-2, lcsh:Medicine, Breast Neoplasms, Biology, Metastasis, Breast cancer, Circulating tumor cell, medicine, Biomarkers, Tumor, Humans, Biomarker Analysis, lcsh:Science, Genetics and Genomics/Cancer Genetics, Oncology/Lung Cancer, Multidisciplinary, lcsh:R, Cancer, medicine.disease, Neoplastic Cells, Circulating, Primary tumor, Pathology/Molecular Pathology, Gene Expression Regulation, Neoplastic, Oncology/Breast Cancer, Cancer research, Biomarker (medicine), lcsh:Q, Cancer biomarkers, Female, Pharmacology/Personalized Medicine, Research Article, Pharmacology/Drug Development
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4
المؤلفون: Elena Prieto, Pablo Moscato, Drew Mellor, Luke Mathieson
المصدر: PLoS ONE, Vol 5, Iss 10, p e13055 (2010)
PLoS ONEمصطلحات موضوعية: Computer science, General Science & Technology, Science, Oncology/Oncology Agents, Parameterized complexity, Context (language use), Computer Science/Numerical Analysis and Theoretical Computing, Computer Science/Applications, Bioinformatics, Oncology/Skin Cancers, Set (abstract data type), Kernel (linear algebra), Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Humans, Pharmacology, Flexibility (engineering), Multidisciplinary, Models, Theoretical, Oncology, Oncology/Breast Cancer, Kernelization, Computer Science, Medicine, Pharmacology/Personalized Medicine, Constant (mathematics), Algorithm, Research Article, Pharmacology/Drug Development
وصف الملف: application/pdf
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5
المؤلفون: Nahida Khan, Valerie A. Longo, Thomas Ku, Peter Smith-Jones, Sean Carlin, Steve Larson
المصدر: PLoS ONE, Vol 5, Iss 5, p e10857 (2010)
PLoS ONEمصطلحات موضوعية: Pathology, medicine.medical_specialty, Biodistribution, Colorectal cancer, Mice, Nude, lcsh:Medicine, Immunofluorescence, 03 medical and health sciences, Mice, 0302 clinical medicine, In vivo, medicine, Animals, Humans, Carbonic Anhydrase IX, lcsh:Science, 030304 developmental biology, Carbonic Anhydrases, Biochemistry/Experimental Biophysical Methods, 0303 health sciences, Multidisciplinary, Oncology/Head and Neck Cancers, Tumor hypoxia, biology, medicine.diagnostic_test, Chemistry, lcsh:R, Antibodies, Monoclonal, medicine.disease, Xenograft Model Antitumor Assays, Cell Hypoxia, 3. Good health, Molecular Imaging, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Radiology and Medical Imaging/PET and SPECT Imaging, lcsh:Q, Antibody, Radiology and Medical Imaging/Radionuclide Imaging, Colorectal Neoplasms, Pharmacology/Personalized Medicine, Perfusion, HT29 Cells, Ex vivo, Oncology/Genitourinary Cancers, Research Article
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6
المؤلفون: Marie-Pierre Podgorniak, Alexandre de la Taille, Bernard Paule, Benyoussef Naimi, Suzanne Menashi, Olivier Cussenot, Emmanuelle Deslandes, Samia Mourah, Yves Allory, Fabien Calvo, Laurence Bastien, Raphaël Porcher
المساهمون: Hématologie -Immunologie -Cibles thérapeutiques, Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Mondor de recherche biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Biostatistique et épidemiologie clinique, CHU Tenon [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Laboratoire de pharmacologie, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Croissance cellulaire, réparation et régénération tissulaires (CRRET), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS), Bases Moleculaires de l'Homeostasie Cutanee : Inflammation, Reparation et Cancer, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Diderot - Paris 7 (UPD7), Laboratoire de pharmacologie expérimentale et clinique : cibles moléculaires en cancérologie ((U 716)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Guellaen, Georges
المصدر: PLoS ONE
PLoS ONE, Public Library of Science, 2010, 5 (5), pp.e10715. ⟨10.1371/journal.pone.0010715⟩
PLoS ONE, Vol 5, Iss 5, p e10715 (2010)
PLoS ONE, 2010, 5 (5), pp.e10715. ⟨10.1371/journal.pone.0010715⟩مصطلحات موضوعية: Male, Vascular Endothelial Growth Factor A, Indoles, Angiogenesis, lcsh:Medicine, Kaplan-Meier Estimate, urologic and male genital diseases, Tyrosine-kinase inhibitor, chemistry.chemical_compound, 0302 clinical medicine, Renal cell carcinoma, Sunitinib, Protein Isoforms, Neoplasm Metastasis, lcsh:Science, 0303 health sciences, Multidisciplinary, Urology/Renal Cancer, Immunohistochemistry, female genital diseases and pregnancy complications, Kidney Neoplasms, 3. Good health, Vascular endothelial growth factor, Gene Expression Regulation, Neoplastic, Vascular endothelial growth factor A, Treatment Outcome, Oncology, 030220 oncology & carcinogenesis, Female, Pharmacology/Personalized Medicine, Tyrosine kinase, medicine.drug, Research Article, medicine.drug_class, Antineoplastic Agents, 03 medical and health sciences, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, medicine, Carcinoma, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Pyrroles, RNA, Messenger, Molecular Biology, Carcinoma, Renal Cell, 030304 developmental biology, business.industry, lcsh:R, medicine.disease, chemistry, Solubility, Cancer research, lcsh:Q, business
وصف الملف: application/pdf
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7
المؤلفون: Bernhard O. Palsson, Li Xie, Roger L. Chang, Lei Xie, Philip E. Bourne
المصدر: PLoS Computational Biology
PLoS Computational Biology, Vol 6, Iss 9, p e1000938 (2010)مصطلحات موضوعية: Proteome, Bioinformatics, Kidney, Kidney Function Tests, Structural bioinformatics, 0302 clinical medicine, Cardiovascular Disorders/Cardiovascular Pharmacology, Drug Discovery, lcsh:QH301-705.5, Biochemistry/Biomacromolecule-Ligand Interactions, Genetics and Genomics/Genetics of Disease, 0303 health sciences, Computational Biology/Systems Biology, Ecology, Genetics and Genomics/Gene Expression, Genetics and Genomics/Bioinformatics, 3. Good health, Systems medicine, Computational Theory and Mathematics, Drug development, Pharmacology/Adverse Reactions, Physiology/Renal, Fluid, and Electrolyte Physiology, Modeling and Simulation, Quinolines, Kidney Diseases, Pharmacology/Personalized Medicine, Algorithms, Metabolic Networks and Pathways, Protein Binding, Research Article, Side effect, Systems biology, Context (language use), Biology, Models, Biological, Cardiovascular Disorders/Hypertension, 03 medical and health sciences, Cellular and Molecular Neuroscience, Computational Biology/Metabolic Networks, Genetics, Humans, Metabolomics, Molecular Biology, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, business.industry, Gene Expression Profiling, Kidney metabolism, Computational Biology, lcsh:Biology (General), ROC Curve, Personalized medicine, business, 030217 neurology & neurosurgery, Pharmacology/Drug Development
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8
المؤلفون: Chao Lin, Stefan Zeuzem, Brian Hare, Ann D. Kwong, Tara L. Kieffer, John C. R. Randle, Varun Garg, Eva Herrmann, Bambang S. Adiwijaya, Christoph Sarrazin, Paul R. Caron
المصدر: PLoS Computational Biology, Vol 6, Iss 4, p e1000745 (2010)
PLoS Computational Biologyمصطلحات موضوعية: Mutation rate, Hepacivirus, Genetic Fitness, Models, Biological, Telaprevir, Evolution, Molecular, Cellular and Molecular Neuroscience, Virology, ddc:570, Drug Resistance, Viral, Genetics, medicine, Humans, Protease inhibitor (pharmacology), Computer Simulation, Protease Inhibitors, Replicon, Molecular Biology, lcsh:QH301-705.5, Ecology, Evolution, Behavior and Systematics, Virology/Antivirals, including Modes of Action and Resistance, Computational Biology/Systems Biology, Ecology, biology, Virology/Persistence and Latency, Viral Load, Pharmacology/Drug Resistance, biology.organism_classification, Hepatitis C, Computational Biology/Evolutionary Modeling, Virology/New Therapies, including Antivirals and Immunotherapy, Computational Theory and Mathematics, Viral replication, lcsh:Biology (General), Modeling and Simulation, Multivariate Analysis, Mutation, RNA, Viral, Pharmacology/Personalized Medicine, Viral load, Oligopeptides, medicine.drug, Research Article, Pharmacology/Drug Development
وصف الملف: application/octet-stream
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9
المؤلفون: Jerome I. Rotter, Joshua D. Smith, Craig L. Hyde, Mark J. Rieder, Daniel I. Chasman, Deborah A. Nickerson, Lara M. Mangravite, Paul M. Ridker, Aurobindo Chatterjee, Ronald M. Krauss, Xiaohui Li, Catherine A. McCarty, Matthew Stephens, Russell A. Wilke, Mathew Barber, Paul T. Williams
المساهمون: Zanger, Ulrich
المصدر: PloS one, vol 5, iss 3
PLoS ONE, Vol 5, Iss 3, p e9763 (2010)
PLoS ONEمصطلحات موضوعية: Oncology, Male, Simvastatin, Atorvastatin, lcsh:Medicine, Genome-wide association study, 030204 cardiovascular system & hematology, Pharmacology, Cardiovascular, 0302 clinical medicine, Cardiovascular Disorders/Cardiovascular Pharmacology, 2.1 Biological and endogenous factors, Aetiology, lcsh:Science, Pravastatin, 0303 health sciences, Multidisciplinary, Single Nucleotide, Middle Aged, Lipids, Cholesterol, Phenotype, lipids (amino acids, peptides, and proteins), Female, Pharmacology/Personalized Medicine, medicine.drug, Research Article, Adult, medicine.medical_specialty, Statin, Genotype, medicine.drug_class, General Science & Technology, Genetics and Genomics/Pharmacogenomics, Single-nucleotide polymorphism, Biology, Polymorphism, Single Nucleotide, 03 medical and health sciences, Clinical Research, Internal medicine, medicine, Genetics, SNP, Humans, Pyrroles, Polymorphism, Atorvastatin Calcium, 030304 developmental biology, Aged, Inflammation, lcsh:R, Human Genome, Bayes Theorem, Atherosclerosis, Heptanoic Acids, lcsh:Q, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Pharmacogenetics, Genome-Wide Association Study
وصف الملف: application/pdf
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10
المؤلفون: Dóra Ghyczy, Gábor Firneisz, Károly Rácz, János Fehér, Barna Wichmann, László Selmeci, Gabriella Lengyel, Zsolt Tulassay, Tímea Varga, Anikó Somogyi
المصدر: PLoS ONE
PLoS ONE, Vol 5, Iss 8, p e12226 (2010)مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, medicine.medical_treatment, Dipeptidyl Peptidase 4, lcsh:Medicine, Type 2 diabetes, Gastroenterology and Hepatology/Hepatology, Liver disease, Insulin resistance, Diabetes mellitus, Internal medicine, Chemical Biology, Medicine, Humans, Prediabetes, Obesity, Diabetes and Endocrinology/Type 2 Diabetes, lcsh:Science, Aged, Multidisciplinary, business.industry, Insulin, lcsh:R, Fatty liver, Case-control study, nutritional and metabolic diseases, Fasting, Middle Aged, medicine.disease, Fatty Liver, Endocrinology, Logistic Models, Diabetes Mellitus, Type 2, Liver, Case-Control Studies, lcsh:Q, Female, Insulin Resistance, business, Pharmacology/Personalized Medicine, Biomarkers, Research Article
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11
المؤلفون: Geetha Menezes, Claudius Mueller, Lucia Pastore, Heather Huryk, Luana Adamo, Emanuel F. Petricoin, Joy Wiedemann, Jasbir Johal, Kirsten H. Edmiston, Jianghong Deng, Khoa D. Tran, Syed Zaman, Rosa I. Gallagher, Virginia Espina, Lance A. Liotta, S. Banks, Brian D. Mariani, James Mize
المصدر: PLoS ONE
PLoS ONE, Vol 5, Iss 4, p e10240 (2010)مصطلحات موضوعية: Oncology, medicine.medical_specialty, Pathology/Histopathology, Cell Survival, Transplantation, Heterologous, lcsh:Medicine, Mice, SCID, Biology, Cell Biology/Cell Signaling, Mice, Breast cancer, Internal medicine, Precursor cell, medicine, Autophagy, Tumor Cells, Cultured, Animals, Humans, Neoplastic transformation, Neoplasm Invasiveness, Stage (cooking), lcsh:Science, skin and connective tissue diseases, neoplasms, Cell survival, Chromosome Aberrations, Women's Health/Breast Cancer, Multidisciplinary, Genome, Human, lcsh:R, Ductal carcinoma, medicine.disease, body regions, Carcinoma, Intraductal, Noninfiltrating, Oncology/Breast Cancer, Surgery/Breast Surgery, Neoplastic Stem Cells, Public Health and Epidemiology/Preventive Medicine, lcsh:Q, Biotechnology/Protein Chemistry and Proteomics, Pharmacology/Personalized Medicine, Human breast, Research Article
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12
المؤلفون: Martin Peifer, Jonathan Weiss, Martin L Sos, Mirjam Koker, Stefanie Heynck, Christian Netzer, Stefanie Fischer, Haridas Rode, Daniel Rauh, Jörg Rahnenführer, Roman K Thomas
المصدر: PLoS ONE
PLoS ONE, Vol 5, Iss 1, p e8919 (2010)مصطلحات موضوعية: Stochastic Processes, Science, Computational Biology, Genetics and Genomics/Pharmacogenomics, Antineoplastic Agents, Drug Synergism, Models, Theoretical, Cell Line, Tumor, Neoplasms, Medicine, Humans, Pharmacology/Personalized Medicine, Oncology/Lung Cancer, Research Article, Pharmacology/Drug Development
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13
المؤلفون: Nico G. Hartwig, Mariska L. Reedijk, Ronald de Groot, David M. Burger, Rob A. Gruters, Albert D. M. E. Osterhaus, Theo M. Luider, Ineke E. van der Ende, Peter C. Burgers, Lennard J. M. Dekker, Jeroen J. A. van Kampen
المساهمون: Neurology, Virology, Pediatrics, Internal Medicine
المصدر: PLoS ONE, Vol 5, Iss 7, p e11409 (2010)
PLoS ONE
PLoS One, 5
PLoS One (print), 5(7). Public Library of Science
PLoS One, 5, 7مصطلحات موضوعية: Infectious diseases and international health [NCEBP 13], Adolescent, lcsh:Medicine, HIV Infections, Pyrimidinones, Pharmacology, Emtricitabine, Lopinavir, Invasive mycoses and compromised host [N4i 2], Pharmacokinetics, SDG 3 - Good Health and Well-being, Abacavir, immune system diseases, medicine, Humans, HIV Protease Inhibitor, Child, lcsh:Science, Chromatography, High Pressure Liquid, Virology/Antivirals, including Modes of Action and Resistance, Ritonavir, Chemistry/Physical, Inorganic, and Analytical Chemistry, Multidisciplinary, business.industry, lcsh:R, Poverty-related infectious diseases [N4i 3], Lamivudine, virus diseases, HIV Protease Inhibitors, Infectious Diseases/HIV Infection and AIDS, Virology, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Leukocytes, Mononuclear, lcsh:Q, Pharmacology/Personalized Medicine, business, Intracellular, Research Article, medicine.drug
وصف الملف: application/pdf
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المؤلفون: Daniel C. Jupiter, Hung Chung Huang, Vincent VanBuren
المصدر: PLoS ONE, Vol 5, Iss 2, p e9056 (2010)
PLoS ONEمصطلحات موضوعية: Candidate gene, Public Health and Epidemiology/Screening, Cardiovascular Disorders, Gene regulatory network, Computational Biology/Transcriptional Regulation, lcsh:Medicine, Biology, Computational Biology/Molecular Genetics, symbols.namesake, Mice, Databases, Genetic, Animals, Cluster Analysis, Gene Regulatory Networks, Genetic Predisposition to Disease, Biomarker discovery, lcsh:Science, Developmental Biology/Embryology, Oligonucleotide Array Sequence Analysis, Regulation of gene expression, Genetics, Expressed sequence tag, Multidisciplinary, Computational Biology/Systems Biology, Models, Genetic, Gene Expression Profiling, Myocardium, lcsh:R, Computational Biology, Gene Expression Regulation, Developmental, Proteins, Heart, Genetics and Genomics/Bioinformatics, Pearson product-moment correlation coefficient, Gene expression profiling, symbols, Biomarker (medicine), lcsh:Q, Pharmacology/Personalized Medicine, Algorithms, Biomarkers, Software, Research Article, Computational Biology/Genomics
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المؤلفون: Gregory D. Jenkins, Richard M. Weinshilboum, Liewei Wang, Krishna R. Kalari, Liang Li, Brooke L. Fridley, Anthony Batzler
المصدر: PLoS ONE, Vol 4, Iss 11, p e7765 (2009)
PLoS ONEمصطلحات موضوعية: Antimetabolites, Antineoplastic, medicine.medical_specialty, lcsh:Medicine, Genome-wide association study, Single-nucleotide polymorphism, Biology, Deoxycytidine, Polymorphism, Single Nucleotide, Linkage Disequilibrium, Inhibitory Concentration 50, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, Molecular genetics, Ethnicity, medicine, Humans, RNA, Messenger, lcsh:Science, Oligonucleotide Array Sequence Analysis, 030304 developmental biology, Pharmacology, Regulation of gene expression, Genetics, 0303 health sciences, Multidisciplinary, Genetics and Genomics/Functional Genomics, lcsh:R, Cytarabine, Genetic Variation, Genetics and Genomics, Gemcitabine, 3. Good health, SNP genotyping, Pharmacogenetics, 030220 oncology & carcinogenesis, Pharmacogenomics, Cancer research, Gene chip analysis, lcsh:Q, Pharmacology/Personalized Medicine, Biomarkers, Research Article, Genome-Wide Association Study, medicine.drug
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المؤلفون: Yuya Kobayashi, Benjamin Ma, Deanna L. Kroetz, Maarke J.E. Roelofs, Sook Wah Yee, Ji Ha Choi, Stephanie Hesselson, Ligong Chen, Connie Ha, Hisayo Fukushima, Pui-Yan Kwok, Harunobu Tahara, Kathleen M. Giacomini, Pär Matsson, Richard M. Myers, Nicolas Picard, James E. Shima, Doug Stryke, Susan J. Johns, Elin Sjödin, Annie Poon, Jason M. Gow, Richard A. Castro, Thomas E. Ferrin
المساهمون: Zanger, Ulrich
المصدر: PloS one, vol 4, iss 9
PLoS ONE, Vol 4, Iss 9, p e6942 (2009)
PLoS ONEمصطلحات موضوعية: Adult, Male, Adolescent, General Science & Technology, Genetics and Genomics/Pharmacogenomics, lcsh:Medicine, ATP-binding cassette transporter, Single-nucleotide polymorphism, Biology, Kidney, 030226 pharmacology & pharmacy, Nucleotide diversity, Promoter Regions, 03 medical and health sciences, 0302 clinical medicine, Gene Frequency, Genetic, Genetics and Genomics/Population Genetics, Genetics, Humans, Polymorphism, Promoter Regions, Genetic, lcsh:Science, Gene, 030304 developmental biology, 0303 health sciences, Multidisciplinary, Polymorphism, Genetic, lcsh:R, Cell Membrane, Kidney metabolism, Genetic Variation, Promoter, Solute carrier family, Pharmacology/Adverse Reactions, Liver, Gene Expression Regulation, Multigene Family, lcsh:Q, ATP-Binding Cassette Transporters, Female, Efflux, Pharmacology/Personalized Medicine, Carrier Proteins, Research Article
وصف الملف: application/pdf
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المؤلفون: Peter J. Lenting, Krista Fischer, Ronan Pendu, Carina J. van Schooten, Cécile V. Denis, Karin van Dijk, H. Marijke van den Berg
المساهمون: Medical Microbiology and Infection Prevention, AII - Infectious diseases, AII - Inflammatory diseases
المصدر: Fischer, K, Pendu, R, van Schooten, C J, van Dijk, K, Denis, C V, van den Berg, H M & Lenting, P J 2009, ' Models for prediction of factor VIII half-life in severe haemophiliacs : Distinct approaches for blood group O and non-O patients ', PLoS ONE, vol. 4, no. 8, e6745 . https://doi.org/10.1371/journal.pone.0006745
PLoS ONE, Vol 4, Iss 8, p e6745 (2009)
PLoS ONE, 4(8):e6745. Public Library of Science
PLoS ONEمصطلحات موضوعية: Adult, congenital, hereditary, and neonatal diseases and abnormalities, Adolescent, animal diseases, Hematology/Coagulation Disorders, lcsh:Medicine, Hemophilia A, ABO Blood-Group System, Cohort Studies, Mice, Young Adult, Von Willebrand factor, In vivo, ABO blood group system, hemic and lymphatic diseases, von Willebrand Factor, Blood plasma, Animals, Humans, Medicine, Platelet, lcsh:Science, Factor VIII, Multidisciplinary, biology, business.industry, lcsh:R, Half-life, Middle Aged, Mice, Inbred C57BL, Immunology, cardiovascular system, biology.protein, lcsh:Q, Pathology/Hematology, Pharmacology/Personalized Medicine, business, Research Article, Half-Life, circulatory and respiratory physiology
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المؤلفون: Aroon D. Hingorani, Tina Shah, Juan P. Casas, Christine Vickery, Liam Smeeth, Michael V. Holmes
المصدر: PLoS ONE
PLoS ONE, Vol 4, Iss 12, p e7960 (2009)مصطلحات موضوعية: Candidate gene, medicine.medical_specialty, MEDLINE, lcsh:Medicine, Genetics and Genomics/Pharmacogenomics, Bioinformatics, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Precision Medicine, lcsh:Science, 030304 developmental biology, Pharmacology, 0303 health sciences, Multidisciplinary, business.industry, United States Food and Drug Administration, lcsh:R, Genetics and Genomics, Pharmacology/Drug Resistance, United States, 3. Good health, Systematic review, Genes, Pharmacology/Adverse Reactions, Sample size determination, Pharmacogenetics, 030220 oncology & carcinogenesis, Meta-analysis, Family medicine, Sample Size, lcsh:Q, Personalized medicine, business, Pharmacology/Personalized Medicine, Primary research, Research Article, Pharmacology/Drug Development
وصف الملف: application/pdf
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المؤلفون: Piercarlo Saletti, Federica Di Nicolantonio, Alberto Bardelli, Giovanna Marrapese, Simona Lamba, Miriam Martini, Luca Mazzucchelli, Francesca Molinari, Andrea Sartore-Bianchi, Salvatore Siena, Sara De Dosso, Tiziana Cipani, Milo Frattini, Michele Nichelatti, Silvio Veronese
المصدر: PLoS ONE
PLoS ONE, Vol 4, Iss 10, p e7287 (2009)مصطلحات موضوعية: Male, endocrine system diseases, Colorectal cancer, cancer biomarkers, medicine.medical_treatment, lcsh:Medicine, medicine.disease_cause, Targeted therapy, Phosphatidylinositol 3-Kinases, lcsh:Science, Aged, 80 and over, Multidisciplinary, Cetuximab, biology, Antibodies, Monoclonal, personalized medicine, Middle Aged, Epidermal Growth Factor Receptor (EGFR), ErbB Receptors, Gene Expression Regulation, Neoplastic, Female, KRAS, Colorectal Neoplasms, Pharmacology/Personalized Medicine, medicine.drug, Research Article, Adult, Proto-Oncogene Proteins B-raf, medicine.drug_class, Class I Phosphatidylinositol 3-Kinases, RAS, BRAF, Genetics and Genomics/Pharmacogenomics, Oncology/Gastrointestinal Cancers, Monoclonal antibody, Proto-Oncogene Proteins p21(ras), Proto-Oncogene Proteins, medicine, PTEN, Panitumumab, Humans, neoplasms, Aged, Retrospective Studies, lcsh:R, PTEN Phosphohydrolase, medicine.disease, digestive system diseases, Genes, ras, Mutation, biology.protein, Cancer research, ras Proteins, Cancer biomarkers, lcsh:Q
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المؤلفون: Isaac S. Kohane, Hui Yao, Patrick Raphael Schmid, Nathan Palmer, Michal Galdzicki, Erxi Wu, Bonnie Berger, Ze Tian
المصدر: PLoS ONE, Vol 4, Iss 4, p e5157 (2009)
PLoS ONEمصطلحات موضوعية: lcsh:Medicine, Biology, Bioinformatics, Polymerase Chain Reaction, Genome, Molecular Biology/Bioinformatics, 03 medical and health sciences, 0302 clinical medicine, Gene expression, Humans, RNA, Messenger, lcsh:Science, Cell Biology/Gene Expression, Oligonucleotide Array Sequence Analysis, 030304 developmental biology, Whole blood, 0303 health sciences, Multidisciplinary, business.industry, Gene Expression Profiling, lcsh:R, Genetics and Genomics/Gene Expression, Globins, Gene expression profiling, 030220 oncology & carcinogenesis, Gene chip analysis, Biomarker (medicine), lcsh:Q, Personalized medicine, DNA microarray, Pharmacology/Personalized Medicine, business, Biomarkers, Research Article