المؤلفون: Yu-Han Chen, Albert P. Ta, Yumay Chen, Hsiao-Chen Lee, Wenjun Fan, Phang-Lang Chen, Maria C. Jordan, Kenneth P. Roos, Grant R. MacGregor, Qin Yang, Robert A. Edwards, Junfeng Li, Ping H. Wang

المصدر: Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-20 (2023)

مصطلحات موضوعية: Mitochondrial AKT, Heart failure, ATP synthase, Mitochondria dysfunction, Diabetic cardiomyopathy, Fatty liver, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-2840

URL الوصول: https://doaj.org/article/b8f23794a64c483a9bcc037647b58465

المؤلفون: Hugo Y-H Lin, Tiffany Shien, Juan-Wei Xu, Yen-Jung Kuo, Phang-Lang Chen, Sheng-Wen Niu, I-Ching Kuo, Hsuan-Fu Kuo, Kai-Chieh Yang, Yi-Ren Yeh

المصدر: PLoS ONE, Vol 19, Iss 8, p e0308385 (2024)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/fd95afd5eb664873aad65e4b27b0675d

المؤلفون: Li-Yun Chang, Yu-Lin Chao, Chien-Chih Chiu, Phang-Lang Chen, Hugo Y.-H. Lin

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 3, p 1518 (2024)

مصطلحات موضوعية: mitochondria, acute kidney injury, AKI, chronic kidney disease, CKD, AKT1, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/3/1518; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/958e39ee3b204c4bbd62b04787476c64

الاتاحة: https://doi.org/10.3390/ijms25031518
https://doaj.org/article/958e39ee3b204c4bbd62b04787476c64

المؤلفون: Phang-Lang Chen, Chi-Fen Chen, Hugo Y.-H. Lin, Daniel J. Riley, Yumay Chen

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 5, p 2936 (2024)

مصطلحات موضوعية: ADPKD, DNA damage repair, checkpoint, PKD1, PKD2, CHK1, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/5/2936; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/6a7f2ac6284e4d9cacfc00a2f9344e6f

الاتاحة: https://doi.org/10.3390/ijms25052936
https://doaj.org/article/6a7f2ac6284e4d9cacfc00a2f9344e6f

المؤلفون: Phang-Lang Chen

المصدر: International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9233

مصطلحات موضوعية: mitochondria, degradosome, mtEXO, SUV3, DSS1, PNPase

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Biochemistry; https://dx.doi.org/10.3390/ijms24119233

الاتاحة: https://doi.org/10.3390/ijms24119233

المؤلفون: Amy X. Zhong, Yumay Chen, Phang-Lang Chen

المصدر: International Journal of Molecular Sciences, Vol 24, Iss 14276, p 14276 (2023)

مصطلحات موضوعية: tumor suppressor gene, BRCA1, breast cancer, tissue specificity, ubiquitination, DNA damage repair, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/24/18/14276; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/339d3d9531644433bb4e8ee59eefb4b1

الاتاحة: https://doi.org/10.3390/ijms241814276
https://doaj.org/article/339d3d9531644433bb4e8ee59eefb4b1

المؤلفون: Wen-Hwa Lee, Phang-Lang Chen, Johnson Lau, Richard Chamberlin, Jiewen Zhu, Longen Zhou, Xiao-Long Qiu, Guikai Wu

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d957a8a4d525912e5c9d74c747ed3e8
https://doi.org/10.1158/0008-5472.22375733.v1

المؤلفون: Jiewen Zhu, Longen Zhou, Guikai Wu, Heiko Konig, Xiaoqin Lin, Guideng Li, Xiao‐Long Qiu, Chi‐Fen Chen, Chun‐Mei Hu, Erin Goldblatt, Ravi Bhatia, A. Richard Chamberlin, Phang‐Lang Chen, Wen‐Hwa Lee

المصدر: EMBO Molecular Medicine, Vol 5, Iss 3, Pp 353-365 (2013)

مصطلحات موضوعية: cancer, CML, inhibitor, RAD51, small molecule, Medicine (General), R5-920, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

URL الوصول: https://doaj.org/article/ee25ef9b483a42d483e59c8e0149a2aa

المؤلفون: Guikai Wu, Xiao-long Qiu, Longen Zhou, Contact The Aacr, Jiewen Zhu, Richard Chamberlin, Johnson Lau, Phang-lang Chen, Wen-hwa Lee

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://cancerres.aacrjournals.org/content/68/20/8393.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.323.5649; http://cancerres.aacrjournals.org/content/68/20/8393.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.323.5649
http://cancerres.aacrjournals.org/content/68/20/8393.full.pdf

المؤلفون: Doi:mol Cell Biol, Wen-hwa Lee, Yumay Chen, Bingnan Gu, Eva Y. -h, P. Lee, Phang-lang Chen, Feng Liu, Suna Cai, Xiaoqin Lin

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://mcb.asm.org/content/25/9/3535.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.598.1030; http://mcb.asm.org/content/25/9/3535.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.598.1030
http://mcb.asm.org/content/25/9/3535.full.pdf

المؤلفون: Qing Zhong, Thomas G Boyer, Phang-Lang Chen, Wen-Hwa Lee

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://mcb.berkeley.edu/labs/zhong/Cancer%20Res%20Jul%2015%202002.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1061.2434; http://mcb.berkeley.edu/labs/zhong/Cancer%20Res%20Jul%2015%202002.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1061.2434
http://mcb.berkeley.edu/labs/zhong/Cancer%20Res%20Jul%2015%202002.pdf

المؤلفون: Mol Cell Biol, Y Chen, D J Riley, P L Chen, W H Lee, Yumay Chen, Daniel J. Riley, Phang-lang Chen, Wen-hwa Lee

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://mcb.asm.org/content/17/10/6049.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.567.4445; http://mcb.asm.org/content/17/10/6049.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.567.4445
http://mcb.asm.org/content/17/10/6049.full.pdf

المؤلفون: C F Chen, Y Chen, K Dai, P L Chen, D J Riley, W H Lee, Mol Cell Biol, After Heat Shock, Chi-fen Chen, Yumay Chen, Kang Dai, Phang-lang Chen, Daniel J. Riley, Wen-hwa Lee

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://mcb.asm.org/content/16/9/4691.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.320.1697; http://mcb.asm.org/content/16/9/4691.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.320.1697
http://mcb.asm.org/content/16/9/4691.full.pdf

المؤلفون: Raymond Gau, Melissa Chang, Daniel J. Riley, Phang Lang Chen, Yumay Chen, Theresa Yu, Amy Zhong

المصدر: Zhong, Amy; Chang, Melissa; Yu, Theresa; Gau, Raymond; Riley, Daniel J; Chen, Yumay; et al.(2018). Aberrant DNA damage response and DNA repair pathway in high glucose conditions.. Journal of cancer research updates, 7(3), 64-74. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5jf8k1rw
Journal of cancer research updates, vol 7, iss 3

مصطلحات موضوعية: 0301 basic medicine, Genome instability, Chemo resistant, Kidney Disease, DNA repair, DNA damage, Metabolic and Endocrine, medicine.disease_cause, DNA damage response, Article, 03 medical and health sciences, Diabetes mellitus, Genetics, medicine, 2.1 Biological and endogenous factors, CHEK1, Cancer, chemistry.chemical_classification, Reactive oxygen species, Chemistry, checkpoint kinase 1, Diabetes, DNA Repair Pathway, medicine.disease, 030104 developmental biology, ATR, Cancer research, Oxidative stress

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee89901e7e29613d5aea4b139c68d360
https://pubmed.ncbi.nlm.nih.gov/30498558

المؤلفون: Jin-yuh Shew, Phang-lang Chen, Robert Bookstein, Y. -h. P. Lee, Wen-hwa Lee

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://cgd.aacrjournals.org/cgi/reprint/1/1/17.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.333.4683; http://cgd.aacrjournals.org/cgi/reprint/1/1/17.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.333.4683
http://cgd.aacrjournals.org/cgi/reprint/1/1/17.pdf

المؤلفون: Heiko Konig, A. Richard Chamberlin, Wen-Hwa Lee, Chun-Mei Hu, Guideng Li, Phang Lang Chen, Erin M. Goldblatt, Xiao Long Qiu, Longen Zhou, Chi Fen Chen, Xiaoqin Lin, Ravi Bhatia, Guikai Wu, Jiewen Zhu

المصدر: EMBO Molecular Medicine
Zhu, Jiewen; Zhou, Longen; Wu, Guikai; Konig, Heiko; Lin, Xiaoqin; Li, Guideng; et al.(2013). A novel small molecule RAD51 inactivator overcomes imatinib-resistance in chronic myeloid leukaemia. EMBO Molecular Medicine, 5(3), 353-365. doi: 10.1002/emmm.201201760. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/1g79t7jg

مصطلحات موضوعية: Indoles, Time Factors, RAD51, Fusion Proteins, bcr-abl, Apoptosis, Mice, SCID, Piperazines, Mice, Mice, Inbred NOD, hemic and lymphatic diseases, Tetrahydroisoquinolines, Medicine and Health Sciences, Homologous Recombination, Cml, CML, Research Articles, Cancer, Radiation, Life Sciences, Synaptonemal Complexes, Protein-Tyrosine Kinases, Tumor Burden, inhibitor, Gene Expression Regulation, Neoplastic, Molecular Docking Simulation, Mammalian-Cells, Benzamides, Imatinib Mesylate, Neoplastic Stem Cells, Molecular Medicine, Female, RNA Interference, biological phenomena, cell phenomena, and immunity, Proteasome Inhibitors, Bcr-Abl, medicine.drug, Proteasome Endopeptidase Complex, Inhibitor, small molecule, Antineoplastic Agents, Protein degradation, Biology, Transfection, Tumor-Cells, Cell Line, Tumor, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, medicine, cancer, Animals, Humans, Progenitor cell, Protein Kinase Inhibitors, Cell Proliferation, Binding Sites, Dose-Response Relationship, Drug, Cell growth, Protein, Imatinib, Small Molecule Dna-Damage Response, medicine.disease, Brc Repeats, enzymes and coenzymes (carbohydrates), Pyrimidines, Drug Resistance, Neoplasm, Cancer cell, Mutation, Rad51, Cancer research, Rad51 Recombinase, Protein Multimerization, Protein Processing, Post-Translational, Repair

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f14ac17cda2b21423a4bf2e416751dc
http://europepmc.org/articles/PMC3598077

المؤلفون: Phang Lang Chen, Ming-Daw Tsai, Pang-Hung Hsu, Wen-Hwa Lee, Kuo-Fen Lee, Yi Hsuan Hsieh, Wen Ting Lo, Jin-Yuh Shew, Xianzhi Jiang, Jui Yun Weng, Mei I. Su, Yi-Cheng Chang, Yung-Ming Jeng, Pei-Chi Wei, Ju Ming Wang

المصدر: Molecular Cell. 48:747-759

مصطلحات موضوعية: Protein Folding, Time Factors, medicine.disease_cause, Mice, chemistry.chemical_compound, Homeostasis, Disulfides, Endoplasmic Reticulum Chaperone BiP, Heat-Shock Proteins, Mice, Knockout, chemistry.chemical_classification, Selenocysteine, Glutathione peroxidase, Endoplasmic Reticulum Stress, Oxidants, Cell biology, Cell Transformation, Neoplastic, Peroxidases, Biochemistry, Oxidation-Reduction, Protein Binding, Signal Transduction, Cell Survival, DNA damage, Biology, Transfection, Article, Cell Line, Tumor, Heat shock protein, medicine, Animals, Humans, Cysteine, Proteostasis Deficiencies, Molecular Biology, Cell Proliferation, Glutathione Peroxidase, Reactive oxygen species, Dose-Response Relationship, Drug, Cell Biology, Fibroblasts, Mice, Inbred C57BL, Oxidative Stress, chemistry, Mutation, Mutagenesis, Site-Directed, Unfolded protein response, Carrier Proteins, Reactive Oxygen Species, Oxidative stress, DNA Damage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4461d17d15363a12ea823c609fad806f
https://doi.org/10.1016/j.molcel.2012.10.007

المؤلفون: Wen-Hwa Lee, Zhanyong Shu, Scot A. Lieser, Dennis Ding-Hwa Wang, Phang Lang Chen

المصدر: Journal of Biological Chemistry. 284:20812-20821

مصطلحات موضوعية: Exosome complex, RNA-dependent RNA polymerase, Biology, Models, Biological, Biochemistry, DEAD-box RNA Helicases, Adenosine Triphosphate, Humans, Molecular Biology, RNA, Double-Stranded, RNA, Cell Biology, Non-coding RNA, RNA Helicase A, Mitochondria, Molecular Weight, RNA: Processing and Catalysis, RNA silencing, Amino Acid Substitution, RNA editing, Exoribonucleases, Mutant Proteins, Protein Multimerization, Degradosome, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2194e7f9c392038698ccd0e9f72290a3
https://doi.org/10.1074/jbc.m109.009605

المؤلفون: A. Richard Chamberlin, Guideng Li, Xiao-Long Qiu, Jiewen Zhu, Wen-Hwa Lee, Phang Lang Chen, Longen Zhou, Guikai Wu

المصدر: Journal of Medicinal Chemistry. 52:1757-1767

مصطلحات موضوعية: Spectrometry, Mass, Electrospray Ionization, Programmed cell death, Magnetic Resonance Spectroscopy, Oncogene, Chemistry, Protein Serine-Threonine Kinases, Protein degradation, Flow Cytometry, Small molecule, Article, Cell killing, Mechanism of action, Biochemistry, Cell culture, Cell Line, Tumor, Drug Discovery, medicine, Humans, NIMA-Related Kinases, Molecular Medicine, medicine.symptom, Protein Kinase Inhibitors, Mitosis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cda0d3917e16efe935e72827f9df4ff
https://doi.org/10.1021/jm8015969

المؤلفون: Chi Fen Chen, Phang Lang Chen, Yumay Chen, Xianzhi Jiang, Daniel J. Riley

المصدر: Cell Cycle. 7:3194-3201

مصطلحات موضوعية: Cell cycle checkpoint, DNA Repair, Ultraviolet Rays, DNA damage, DNA repair, Recombinant Fusion Proteins, Cell Cycle Proteins, Protein Serine-Threonine Kinases, Biology, Article, Cell Line, Mice, Radiation, Ionizing, Animals, Humans, NIMA-Related Kinase 1, CHEK1, Molecular Biology, Checkpoint Kinase 2, Mice, Knockout, Cell Cycle, DNA, Cell Biology, Cell cycle, G2-M DNA damage checkpoint, Cell biology, Enzyme Activation, Checkpoint Kinase 1, RNA Interference, Protein Kinases, DNA Damage, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1c56f5704c3f63b74c68afbf1040cc
https://doi.org/10.4161/cc.7.20.6815