المؤلفون: Kathleen Connolly, Richard George, Sami Omar, Elin Matsson, Magnus Åstrand, Magnus Althage, Daniel Pettersen, Esha Mohamed, Kelly Fang, Joao A. C. Lima, Mirjana Kujacic, Helena Ödesjö, Michelle Turton, Petra Johannesson, Anders Gabrielsen, Marcin Ufnal

المصدر: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 15 (2024)

مصطلحات موضوعية: AZD3427, HFmrEF, HFpEF, HFrEF, relaxin, RXFP1, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2047-9980

URL الوصول: https://doaj.org/article/c0e3f5861c8c440da59d8312baa97e0d

المؤلفون: Tord Inghardt, Thomas Antonsson, Cecilia Ericsson, Daniel Hovdal, Petra Johannesson, Carina Johansson, Ulrik Jurva, Johan Kajanus, Bengt Kull, Erik Michaëlsson, Anna Pettersen, Tove Sjögren, Henrik Sörensen, Kristina Westerlund, Eva-Lotte Lindstedt

المصدر: Journal of Medicinal Chemistry. 65:11485-11496

مصطلحات موضوعية: Heart Failure, Pyrimidines, Drug Discovery, Animals, Humans, Molecular Medicine, Pyrroles, Stroke Volume, Iodide Peroxidase, Peroxidase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ef1bcb1b44e92cc2a14d39e9d3d4b8
https://doi.org/10.1021/acs.jmedchem.1c02141

المؤلفون: Eva Lamm Bergström, Fredrik Wågberg, Christian Tyrchan, Anders Lundqvist, Ulf Andersson, Xiao-Hong Zhou, Robert Ronn, Linda Swedin, Grigorios Nikitidis, Fanyi Jiang, Victoria Ullah, Antonios Nikitidis, Petra Johannesson, Eva Björkstrand, Hui-Fang Chang, Theresa Andreasson, Lena Ripa, Magnus Munck af Rosenschöld, Pernilla Glader, Anna Pettersen, Britta Bonn, Margareta Ek, Andrew M. Davis, Euan Gordon, Helena Käck, Dave Chapman, Mattias Rohman, Anna Malmberg

المصدر: Journal of Medicinal Chemistry. 62:7769-7787

مصطلحات موضوعية: chemistry.chemical_classification, 0303 health sciences, Ligand efficiency, Leukotriene C4, Pharmacology, 01 natural sciences, Peripheral blood mononuclear cell, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, chemistry.chemical_compound, Enzyme, chemistry, In vivo, Pharmacodynamics, Drug Discovery, Molecular Medicine, Potency, IC50, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::76db67d7944baf037a5f82180c0e160c
https://doi.org/10.1021/acs.jmedchem.9b00555

المؤلفون: Tord Inghardt, Thomas Antonsson, Cecilia Ericsson, Daniel Hovdal, Petra Johannesson, Carina Johansson, Ulrik Jurva, Johan Kajanus, Bengt Kull, Erik Michaëlsson, Anna Pettersen, Tove Sjögren, Henrik Sörensen, Kristina Westerlund, Eva-Lotte Lindstedt

المصدر: Journal of Medicinal Chemistry. 65:13482-13482

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::762527e04301766c31eec6829fdf10d1
https://doi.org/10.1021/acs.jmedchem.2c01533

المؤلفون: Kristina Berggren, Nils-Olov Hermansson, Petra Johannesson, Annika Wellner, Jonas Brånalt, Kristina Nilsson, Henrik Gradén, Maria Ölwegård-Halvarsson, Ola Fjellström, Bengt Ohlsson, Terese Andersson, Öjvind Davidsson, Linda Gustafsson, Christian Tyrchan, Yantao Chen, Frank Jansen, Eric Wellner

المصدر: Bioorganicmedicinal chemistry letters. 30(4)

مصطلحات موضوعية: Agonist, medicine.drug_class, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, 01 natural sciences, Biochemistry, Receptors, G-Protein-Coupled, chemistry.chemical_compound, Structure-Activity Relationship, In vivo, Drug Discovery, medicine, Peptide bond, Humans, Urea, Receptor, Receptors, Ghrelin, Molecular Biology, G protein-coupled receptor, 010405 organic chemistry, Chemistry, Organic Chemistry, Lipid metabolism, Combinatorial chemistry, Amides, 0104 chemical sciences, High-Throughput Screening Assays, 010404 medicinal & biomolecular chemistry, Molecular Medicine, Linker, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::539ac9eaa5f8cfea396b0726436c5a3b
https://pubmed.ncbi.nlm.nih.gov/31932225

المؤلفون: Magnus, Munck Af Rosenschöld, Petra, Johannesson, Antonios, Nikitidis, Christian, Tyrchan, Hui-Fang, Chang, Robert, Rönn, Dave, Chapman, Victoria, Ullah, Grigorios, Nikitidis, Pernilla, Glader, Helena, Käck, Britta, Bonn, Fredrik, Wågberg, Eva, Björkstrand, Ulf, Andersson, Linda, Swedin, Mattias, Rohman, Theresa, Andreasson, Eva Lamm, Bergström, Fanyi, Jiang, Xiao-Hong, Zhou, Anders J, Lundqvist, Anna, Malmberg, Margareta, Ek, Euan, Gordon, Anna, Pettersen, Lena, Ripa, Andrew M, Davis

المصدر: Journal of medicinal chemistry. 62(17)

مصطلحات موضوعية: Dose-Response Relationship, Drug, Molecular Structure, Administration, Oral, Asthma, Rats, Disease Models, Animal, Structure-Activity Relationship, Pyrazines, Drug Discovery, Animals, Humans, Anti-Asthmatic Agents, Enzyme Inhibitors, Glutathione Transferase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::14a2759a1fc1e1a9c5c1ce4c83ae3c85
https://pubmed.ncbi.nlm.nih.gov/31415176

المؤلفون: Nicholas D. Oakes, John Wiseman, Petra Johannesson, Pia Thalén, Gerhard Böttcher, Kristina Wallenius, Ola Fjellström, Jan-Arne Björkman

المصدر: JCI Insight. 2

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Afferent arterioles, Lipolysis, Mice, Obese, GPR81, Fatty Acids, Nonesterified, Diabetes Mellitus, Experimental, Receptors, G-Protein-Coupled, Microcirculation, 03 medical and health sciences, Dogs, Renal Artery, Insulin resistance, Internal medicine, Diabetes mellitus, Adipocytes, medicine, Animals, Rats, Wistar, Kidney, Dose-Response Relationship, Drug, Receptors, Endothelin, business.industry, Endothelins, General Medicine, medicine.disease, Arterioles, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Hypertension, Vascular resistance, Vascular Resistance, Insulin Resistance, Endothelin receptor, business, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d37712ec3dc738bfb5a7a563eedbfa4
https://doi.org/10.1172/jci.insight.92564

المؤلفون: Göran Dahl, Amanda Van de Poël, James Root, Steve Swallow, Philip Gardiner, Hans Lönn, Cecilia Wikell, Helena Käck, Kevin James Doyle, Kristina Stenvall, Petra Johannesson, Stephen Connolly

المصدر: Journal of medicinal chemistry. 59(20)

مصطلحات موضوعية: 0301 basic medicine, Administration, Oral, 01 natural sciences, Cathepsin C, 03 medical and health sciences, Mice, Structure-Activity Relationship, Dogs, Drug Discovery, Structure–activity relationship, Animals, Humans, Protease Inhibitors, Benzoxazoles, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Drug discovery, U937 Cells, Combinatorial chemistry, 0104 chemical sciences, Rats, 010404 medicinal & biomolecular chemistry, Oxazepines, 030104 developmental biology, Covalent bond, Molecular Medicine, Rabbits, Once daily

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d01311276b7fd892ed85c1abef6728
https://pubmed.ncbi.nlm.nih.gov/27690432

المؤلفون: Nils Pemberton, Henrik Gradén, Per H. Svensson, Emma Evertsson, Petra Johannesson, Matti Lepistö, Emma Bratt

المصدر: ACS Medicinal Chemistry Letters. 3:574-578

مصطلحات موضوعية: chemistry.chemical_classification, Chemistry, Chemical structure, Carboxylic acid, Aryl, Organic Chemistry, Ring (chemistry), Biochemistry, Combinatorial chemistry, Amino acid, chemistry.chemical_compound, Sulfinamide, Drug Discovery, Organic chemistry, Tetrazole, Bioisostere

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46e16a225002fdb63d341f3505dd0de
https://doi.org/10.1021/ml3000935

المؤلفون: Sara Holmqvist, Thomas Elebring, Jane E. Moore, Magnus Johansson, Fritiof Ponten, Shalini Andersson, Petra Johannesson, Steve Chapman, Craig S. Donald, Paul Robert Owen Whittamore, Paul Schofield, Jonas A. Pettersson, Robert D. M. Davies, Sue Bowker, Craig Johnstone, Malin Lemurell, Bryan J. Egner, Paul D. Kemmitt, Tord Inghardt, Jan Kihlberg, Pernilla Korsgren, Nidhal Selmi, Annika Björe, Helen Pointon, Alan Armstrong

المصدر: Drug Discovery Today. 14:598-604

مصطلحات موضوعية: Quality Control, Pharmacology, Time Factors, business.industry, Process (engineering), Chemistry, Pharmaceutical, media_common.quotation_subject, Six Sigma, Lean laboratory, medicine.disease, Medicinal chemistry, Lean project management, Pharmaceutical Preparations, Drug Discovery, Employee engagement, medicine, Animals, Humans, Quality (business), Attrition, business, Pharmaceutical industry, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412cd92df3b770742b045849e931d545
https://doi.org/10.1016/j.drudis.2009.03.005

المؤلفون: Maria Almeida, Arne Boman, Petra Johannesson, Torbjörn Lundstedt

المصدر: Journal of Labelled Compounds and Radiopharmaceuticals. 48:621-627

مصطلحات موضوعية: Stereochemistry, Bicarbonate, Organic Chemistry, Carbon-13, Biochemistry, Medicinal chemistry, Chemical synthesis, Analytical Chemistry, Acylation, chemistry.chemical_compound, chemistry, Succinic acid, Amide, Drug Discovery, Radiology, Nuclear Medicine and imaging, Carbon-14, Spectroscopy, Pyrrole

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e8d5ce2dab3507174bcc470044b30cbe
https://doi.org/10.1002/jlcr.957

المؤلفون: Per-Anders Frändberg, and Anders Karlén, Fred Nyberg, Gunnar Lindeberg, Máté Erdélyi, Anders Hallberg, Petra Johannesson

المصدر: Journal of Medicinal Chemistry. 47:6009-6019

مصطلحات موضوعية: Models, Molecular, Magnetic Resonance Spectroscopy, Swine, Stereochemistry, Molecular Conformation, Peptide, In Vitro Techniques, Receptor, Angiotensin, Type 2, Chemical synthesis, Receptor, Angiotensin, Type 1, Radioligand Assay, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Peptide synthesis, Animals, Dimethyl Sulfoxide, Tyrosine, chemistry.chemical_classification, Dipeptide, Bicyclic molecule, Angiotensin II, Molecular Mimicry, Uterus, Dipeptides, Bridged Bicyclo Compounds, Heterocyclic, Crown Compounds, Rats, Solutions, Liver, chemistry, Molecular Medicine, Female, Cysteine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ec463743d0f608f3fa01225158a219
https://doi.org/10.1021/jm049651m

المؤلفون: Petra Johannesson, Barbro Synnergren, Gregory V. Nikiforovich, and Anders Karlén, Gunnar Lindeberg, F Nyberg, Anders Hallberg, Adolf Gogoll, Anja Johansson, Madeleine Le Grèves

المصدر: Journal of Medicinal Chemistry. 45:1767-1777

مصطلحات موضوعية: Male, Models, Molecular, Agonist, Vinyl Compounds, Double bond, Sulfide, Stereochemistry, medicine.drug_class, Molecular Conformation, Stereoisomerism, In Vitro Techniques, Sulfides, Binding, Competitive, Peptides, Cyclic, Muscle, Smooth, Vascular, Receptor, Angiotensin, Type 1, Radioligand Assay, Structure-Activity Relationship, Drug Discovery, medicine, Animals, Conformational isomerism, Aorta, Chromatography, High Pressure Liquid, chemistry.chemical_classification, Receptors, Angiotensin, Angiotensin II, Peptide Fragments, Cyclic peptide, Rats, Liver, chemistry, Molecular Medicine, Rabbits, Cis–trans isomerism, Muscle Contraction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::463d78f2d428e8349fd74b9058ab6db0
https://doi.org/10.1021/jm011063a

المؤلفون: and Anders Karlén, Anders Hallberg, Gunnar Lindeberg, Weimin Tong, Petra Johannesson, Adolf Gogoll

المصدر: Journal of Medicinal Chemistry. 42:601-608

مصطلحات موضوعية: Models, Molecular, Magnetic Resonance Spectroscopy, Stereochemistry, Thiazolidine, Peptide, CHO Cells, Tripeptide, In Vitro Techniques, Receptor, Angiotensin, Type 2, Protein Structure, Secondary, Receptor, Angiotensin, Type 1, Turn (biochemistry), Radioligand Assay, chemistry.chemical_compound, Cricetinae, Drug Discovery, Peptide synthesis, Animals, Vasoconstrictor Agents, chemistry.chemical_classification, Receptors, Angiotensin, Angiotensin II receptor type 1, Bicyclic molecule, Angiotensin II, Molecular Mimicry, Rats, Liver, chemistry, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79830fb30d2dcfe995095eb2026f9422
https://doi.org/10.1021/jm981077p

المؤلفون: Emre M. Isin, David Blomberg Saitton, Eric Wellner, Rutger H. A. Folmer, Pernilla Ståhlberg, Kay Brickmann, Volker Schnecke, Öjvind Davidsson, Christoffer Bengtsson, Lars-Olof Larsson, Stefan Hallén, Pernilla Sörme, Hong Wan, Kenth Hallberg, Linda Öster, Ragnar Hovland, Lars Löfgren, Alleyn T. Plowright, Bengt Kull, Tobias Noeske, Stefan Blaho, Petra Johannesson, Tomas Drmota, Kristina Nilsson, Johan Broddefalk, Nick Oakes

المصدر: Bioorganicmedicinal chemistry. 19(10)

مصطلحات موضوعية: Male, Models, Molecular, Tertiary amine, Clinical Biochemistry, Pharmaceutical Science, Crystallography, X-Ray, Biochemistry, Small Molecule Libraries, chemistry.chemical_compound, Mice, Structure-Activity Relationship, In vivo, Drug Discovery, Animals, Humans, Obesity, Enzyme Inhibitors, Molecular Biology, ADME, chemistry.chemical_classification, biology, Organic Chemistry, Fatty Acids, Acetyl-CoA carboxylase, Acetyl-CoA Carboxylase 1, Rats, Rats, Zucker, Malonyl Coenzyme A, Mice, Inbred C57BL, Enzyme, Malonyl-CoA, chemistry, Diabetes Mellitus, Type 2, Liver, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Acetyl-CoA Carboxylase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab801bb919b253dd5e5e3a7b103724d
https://pubmed.ncbi.nlm.nih.gov/21515056

المؤلفون: Gunnar Lindeberg, Weimin Tong, Adolf Gogoll, Anders Karlén, Petra Johannesson, Anders Hallberg

المصدر: Peptides for the New Millennium ISBN: 0792364457

مصطلحات موضوعية: Chain length, Peptide analog, Chemistry, Stereochemistry, Strategic research, Regioselectivity, Target peptide, Combinatorial chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b705cbc1ee4f155d3d9127ed70b10ee4
https://doi.org/10.1007/0-306-46881-6_63

المؤلفون: Gunnar Lindeberg, Gregory V. Nikiforovich, Adolf Gogoll, Anja Johansson, Anders Karlén, Petra Johannesson, Anders Hallberg

المصدر: Peptides: The Wave of the Future ISBN: 9789401039055

مصطلحات موضوعية: chemistry.chemical_classification, Alternative methods, Angiotensin II receptor type 1, Sulfide, chemistry, Bicyclic molecule, Stereochemistry, Organic chemistry, Aldehyde, Angiotensin II

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::03c212ae6848e1117d1dfe5397ba4f28
https://doi.org/10.1007/978-94-010-0464-0_63

المؤلفون: Anders Hallberg, Adolf Gogoll, Gunnar Lindeberg, Barbro Synnergren, Petra Johannesson, and Anders Karlén, Fred Nyberg, Weimin Tong

المصدر: Journal of medicinal chemistry. 42(22)

مصطلحات موضوعية: Models, Molecular, Molecular model, Stereochemistry, Tripeptide, CHO Cells, Chemical synthesis, Aldehyde, Binding, Competitive, Receptor, Angiotensin, Type 2, Protein Structure, Secondary, Receptor, Angiotensin, Type 1, chemistry.chemical_compound, Radioligand Assay, Structure-Activity Relationship, Cricetinae, Drug Discovery, Peptide synthesis, Animals, chemistry.chemical_classification, Oligopeptide, Aza Compounds, Receptors, Angiotensin, Bicyclic molecule, Chemistry, Angiotensin II, Molecular Mimicry, Stereoisomerism, Bridged Bicyclo Compounds, Heterocyclic, Rats, Molecular Medicine, Oligopeptides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd4b2b7ab179fa62ab6f451c959de40
https://pubmed.ncbi.nlm.nih.gov/10579816