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1
المؤلفون: Goran Malojčić, Martine Brault, Ines H. Kaltheuner, Lewis C. Cantley, Patrick Deroy, Heeyoun Bunch, Shanhu Hu, Janet Iwasa, Robin D. Dowell, Michael J. Bradley, Christian Clavette, Limei Tao, Peter W. White, Matthias Geyer, Zachary C. Poss, William M. Old, Zachary L. Maas, Shraddha Nayak, Tim-Michael Decker, Christopher C. Ebmeier, Benjamin Erickson, Leah J. Damon, David Bentley, Jenna K. Rimel, Tomer M. Yaron, Jason J. Marineau, Jared L. Johnson, Kristin B. Hamman, Dylan J. Taatjes
المصدر: Genes Dev
مصطلحات موضوعية: Transcription, Genetic, Cell Survival, RNA polymerase II, HL-60 Cells, Biology, Models, Biological, 03 medical and health sciences, 0302 clinical medicine, Transcription (biology), Genetics, Humans, 030304 developmental biology, 0303 health sciences, Kinase, Cyclin-Dependent Kinases, Cell biology, Enzyme Activation, Alternative Splicing, 030220 oncology & carcinogenesis, RNA splicing, Transcription factor II H, biology.protein, Cyclin-dependent kinase 9, Cyclin-dependent kinase 7, Transcription Factor TFIIH, Cyclin-Dependent Kinase-Activating Kinase, Developmental Biology, CDK12, Research Paper
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2Academic Journal
المؤلفون: Jacques Archambault, Ewald Welchner, Jean Rancourt, Mireille Cartier, Peter W. White, Anne-marie Faucher, Human Papillomavirus, Type E Helicase
المساهمون: The Pennsylvania State University CiteSeerX Archives
وصف الملف: application/pdf
Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.495.4043; http://aac.asm.org/content/49/12/4834.full.pdf
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3Academic Journal
المؤلفون: Diane Thibeault, Christiane Bousquet, Rock Gingras, Lisette Lagacé, Roger Maurice, Peter W. White, Daniel Lamarre
المساهمون: The Pennsylvania State University CiteSeerX Archives
وصف الملف: application/pdf
Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.328.6139; http://jvi.asm.org/content/78/14/7352.full.pdf
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4
المصدر: European journal of medicinal chemistry. 192
مصطلحات موضوعية: Steric effects, Stereochemistry, Enthalpy, Substituent, Viral Nonstructural Proteins, Ligands, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, Drug Discovery, Side chain, Phenyl group, Protease Inhibitors, 030304 developmental biology, Pharmacology, 0303 health sciences, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Organic Chemistry, Isothermal titration calorimetry, General Medicine, 0104 chemical sciences, 3. Good health, chemistry, Thermodynamics, Oligopeptides, Methyl group, Entropy (order and disorder)
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5Academic Journal
المؤلفون: Papillomavirus Type, E Helicase, Steve Titolo, Alex Pelletier, Anne-marie Pulichino, Elizabeth Wardrop, Peter W. White, Michael G, Jacques Archambault, Karine Brault, Michael G. Cordingley
المساهمون: The Pennsylvania State University CiteSeerX Archives
وصف الملف: application/pdf
Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.321.2715; http://jvi.asm.org/content/74/16/7349.full.pdf
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6Academic Journal
المؤلفون: G. Cordingley, Jacques Archambault, Elizabeth Wardrop, Peter W. White, Anthony Amin, Steve Titolo, Alex Pelletier, Frédéric Sauvé, Karine Brault, Michael G. Cordingley
المساهمون: The Pennsylvania State University CiteSeerX Archives
وصف الملف: application/pdf
Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.604.3429; http://jvi.asm.org/content/73/7/5282.full.pdf
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7
المؤلفون: Samuel B. Adams, Travis J. Dekker, Kamran S. Hamid, Peter W White
المصدر: Foot & Ankle Specialist. 10:51-54
مصطلحات موضوعية: medicine.medical_specialty, business.industry, Radiography, Radiodensity, 030229 sport sciences, Ankle fracture surgery, Surgery, 03 medical and health sciences, Prone position, Fixation (surgical), 0302 clinical medicine, medicine.anatomical_structure, 030220 oncology & carcinogenesis, medicine, Orthopedics and Sports Medicine, Contralateral limb, Podiatry, Ankle, business, Fluoroscopic imaging
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8
المؤلفون: Peter W. White, Kevork Mekhssian, Craig Fenwick, Rock Gingras, Diane Thibeault
المصدر: SLAS Discovery. 19:259-269
مصطلحات موضوعية: Antiserum, Oligoribonucleotides, High-throughput screening, RNA, Genome, Viral, Biology, Virus Replication, medicine.disease_cause, Stem-loop, Biochemistry, High-Throughput Screening Assays, Analytical Chemistry, Viral life cycle, medicine, biology.protein, Humans, RNA, Viral, Tyrosine, Molecular Medicine, Rhinovirus, Primer (molecular biology), Uridine, Polymerase, Biotechnology
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9
المؤلفون: Murray D. Bailey, Peter W. White, Josée Bordeleau, Michel Garneau, Jeff A. O'Meara, Mélissa Leblanc, Montse Llinas-Brunet, Christopher T. Lemke
المصدر: Bioorganic & Medicinal Chemistry Letters. 23:4447-4452
مصطلحات موضوعية: Models, Molecular, Peptidomimetic, medicine.medical_treatment, Hepatitis C virus, Clinical Biochemistry, Pharmaceutical Science, Literature based, Hepacivirus, Viral Nonstructural Proteins, Cleavage (embryo), medicine.disease_cause, Biochemistry, Structure-Activity Relationship, Dogs, Drug Discovery, medicine, Animals, Humans, Protease Inhibitors, Molecular Biology, Serine protease, NS3, Protease, biology, Chemistry, Organic Chemistry, Succinates, Haplorhini, Amides, Combinatorial chemistry, Rats, Peptide backbone, Microsomes, Liver, biology.protein, Molecular Medicine, Half-Life
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10
المؤلفون: Vida Gorys, Peter W. White, Josée Bordeleau, Cédrickx Godbout, Jeff A. O'Meara, Michel Garneau, Benoît Moreau, Elisia Villemure, Mélissa Leblanc, Montse Llinas-Brunet
المصدر: Journal of Medicinal Chemistry. 57:1770-1776
مصطلحات موضوعية: Spectrometry, Mass, Electrospray Ionization, NS3, Magnetic Resonance Spectroscopy, Protease, Chemistry, medicine.medical_treatment, Hepatitis C virus, Viral Nonstructural Proteins, Pharmacology, Crystallography, X-Ray, medicine.disease_cause, Virology, Liver, Drug Discovery, Hcv protease, medicine, Hepatitis C Virus NS3/4A Protease Inhibitors, Humans, Molecular Medicine, Distribution (pharmacology), Potency, Protease Inhibitors, ADME
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11
المؤلفون: Lisette Lagacé, George Kukolj, Benoît Moreau, Peter W. White, Cédrickx Godbout, Montse Llinas-Brunet, Diane Thibeault, Christopher T. Lemke, Jeff A. O'Meara
المصدر: Journal of Biological Chemistry. 288:5673-5681
مصطلحات موضوعية: Models, Molecular, Proteases, Genotype, Hepatitis C virus, medicine.medical_treatment, Molecular Conformation, Drug resistance, Viral Nonstructural Proteins, Biology, Crystallography, X-Ray, medicine.disease_cause, Antiviral Agents, Biochemistry, Cell Line, Drug Resistance, Viral, medicine, Humans, Potency, Protease Inhibitors, Protease inhibitor (pharmacology), Cloning, Molecular, Molecular Biology, Serine protease, Sulfonamides, NS3, Protease, X-Rays, Intracellular Signaling Peptides and Proteins, Molecular Bases of Disease, Cell Biology, Hepatitis C, Virology, Models, Chemical, biology.protein, Carrier Proteins
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12
المؤلفون: Kamran S, Hamid, Travis J, Dekker, Peter W, White, Samuel B, Adams
المصدر: Footankle specialist. 10(1)
مصطلحات موضوعية: Intraoperative Care, Fluoroscopy, Prone Position, Humans, Ankle Fractures, Ankle Joint, Patient Positioning
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13
المؤلفون: Christian Trepo, Michael P. Manns, David Wright, Jose Luis Calleja, Peter W. White, Chan-Loi Yong, Stanislas Pol, George Kukolj, Jerry O. Stern, Marc Bourlière, Maurizio Bonacini, Thomas Berg, Wulf Otto Boecher, Yves Benhamou, Gerhard G. Steinmann, Joe Scherer
المساهمون: Department of Gastroenterology, Hepatology and Endocrinology (MHH), Hannover Medical School [Hannover] (MHH), Hôpital saint joseph, Service d' Hépato-gastroentérologie, Service d'Hépato-Gastro-Entérologie [CHU Pitié-Salpêtrière], CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Service d'hépatologie médicale [CHU Cochin], Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), California Pacific medical research center institute, Pacific medical center, Centre de Recherche en Cancérologie de Lyon (UNICANCER/CRCL), Centre Léon Bérard [Lyon]-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), IFR Laennec (IL), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Department of Psychiatry and Behavioural Neurosciences, McMaster University [Hamilton, Ontario]-Offord Centre for Child Studies, University Clinic, University Clinic, Leipzig, Hospital universitano Puerta de Hierro, hospital universitano puerta de hierro, Service d'Hépato-Gastroentérologie [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Pitié-Salpêtrière [APHP], CHU Cochin [AP-HP]-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP), Centre de Recherche en Cancérologie de Lyon (CRCL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre Léon Bérard [Lyon]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Department of Gastroenterology, Hepatology and Endocrinology ( MHH ), Hannover Medical School [Hannover] ( MHH ), Assistance publique - Hôpitaux de Paris (AP-HP)-CHU Pitié-Salpêtrière [APHP], Institut Cochin ( UM3 (UMR 8104 / U1016) ), Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Centre National de la Recherche Scientifique ( CNRS ), Assistance publique - Hôpitaux de Paris (AP-HP)-CHU Cochin [AP-HP], Centre de Recherche en Cancérologie de Lyon ( CRCL ), Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-Centre Léon Bérard [Lyon]-Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Centre National de la Recherche Scientifique ( CNRS ), IFR Laennec ( IL ), Institut National de la Recherche Agronomique ( INRA ) -Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-Université Jean Monnet [Saint-Étienne] ( UJM ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Centre National de la Recherche Scientifique ( CNRS )
المصدر: Journal of Hepatology
Journal of Hepatology, Elsevier, 2011, 54 (6), pp.1114-22. ⟨10.1016/j.jhep.2010.08.040⟩
Journal of Hepatology, Elsevier, 2011, 54 (6), pp.1114-22. 〈10.1016/j.jhep.2010.08.040〉مصطلحات موضوعية: Male, Aminoisobutyric Acids, Hepacivirus, MESH : Viral Load, Viral Nonstructural Proteins, medicine.disease_cause, Gastroenterology, MESH : Hepacivirus, [ SDV.CAN ] Life Sciences [q-bio]/Cancer, Polyethylene Glycols, MESH: Recombinant Proteins, chemistry.chemical_compound, 0302 clinical medicine, MESH : Thiazoles, Pegylated interferon, MESH : Female, MESH: Double-Blind Method, MESH: Hepacivirus, MESH : Viral Nonstructural Proteins, 0303 health sciences, MESH: Middle Aged, MESH: Protease Inhibitors, MESH: Drug Resistance, Viral, biology, MESH : Polyethylene Glycols, Intracellular Signaling Peptides and Proteins, MESH : Adult, Middle Aged, Viral Load, Hepatitis C, Recombinant Proteins, MESH : Antiviral Agents, 3. Good health, MESH : Drug Resistance, Viral, MESH: Oligopeptides, Quinolines, MESH : Interferon-alpha, Female, 030211 gastroenterology & hepatology, MESH : Carrier Proteins, MESH: Interferon-alpha, MESH: Viral Load, Oligopeptides, Viral load, medicine.drug, Pegylated Interferon Alfa, MESH : Oligopeptides, Adult, MESH: Antiviral Agents, medicine.medical_specialty, MESH : Protease Inhibitors, Proline, MESH : Recombinant Proteins, MESH : Male, Hepatitis C virus, MESH: Thiazoles, MESH: Carrier Proteins, [SDV.CAN]Life Sciences [q-bio]/Cancer, Interferon alpha-2, Antiviral Agents, 03 medical and health sciences, Double-Blind Method, Leucine, MESH: Ribavirin, Internal medicine, Drug Resistance, Viral, Ribavirin, medicine, MESH : Double-Blind Method, Humans, MESH : Middle Aged, Protease Inhibitors, Protease inhibitor (pharmacology), 030304 developmental biology, MESH: Hepatitis C, MESH: Humans, Hepatology, business.industry, MESH : Humans, Interferon-alpha, MESH: Adult, MESH : Hepatitis C, biology.organism_classification, MESH: Male, MESH : Ribavirin, Thiazoles, MESH: Polyethylene Glycols, chemistry, Faldaprevir, Immunology, MESH: Viral Nonstructural Proteins, Carrier Proteins, business, MESH: Female
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14
المؤلفون: Peter W. White, Oliver Hucke, Montse Llinas-Brunet, Songping Zhao, Diane Thibeault, Nathalie Goudreau, Christopher T. Lemke
المصدر: Journal of Biological Chemistry. 286:11434-11443
مصطلحات موضوعية: Aminoisobutyric Acids, Proline, Stereochemistry, medicine.medical_treatment, Hepacivirus, Hepatitis C virus, Plasma protein binding, Viral Nonstructural Proteins, Crystallography, X-Ray, medicine.disease_cause, Biochemistry, Leucine, Catalytic Domain, Catalytic triad, medicine, Humans, Protease Inhibitors, Enzyme kinetics, Nuclear Magnetic Resonance, Biomolecular, Molecular Biology, NS3, Protease, Clinical Trials, Phase I as Topic, biology, Chemistry, Intracellular Signaling Peptides and Proteins, Active site, Cell Biology, biology.organism_classification, Hepatitis C, Thiazoles, Protein Structure and Folding, Quinolines, biology.protein, Carrier Proteins, Oligopeptides, Protein Binding
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15
المؤلفون: Marc-André Poupart, Peter W. White, Ghiro Elise, Nathalie Goudreau, Josée Bordeleau, Julie Naud, Yves Bousquet, Montse Llinas-Brunet, Michel Garneau, Sylvie Goulet, Pat Forgione, Jiamin Duan, Vida Gorys, Stephen H. Kawai, Michael Bös, Punit Bhardwaj, Ted Halmos, Murray D. Bailey, Michael G. Cordingley
المصدر: Journal of Medicinal Chemistry. 53:6466-6476
مصطلحات موضوعية: Male, Aminoisobutyric Acids, Serine Proteinase Inhibitors, Proline, Stereochemistry, medicine.medical_treatment, Substituent, Hepacivirus, Tripeptide, Viral Nonstructural Proteins, Antiviral Agents, Rats, Sprague-Dawley, Structure-Activity Relationship, chemistry.chemical_compound, Leucine, Drug Discovery, medicine, Animals, Humans, Moiety, Structure–activity relationship, Potency, NS3, Protease, Quinoline, Rats, Thiazoles, chemistry, Biochemistry, Microsomes, Liver, Quinolines, Molecular Medicine, Replicon, Oligopeptides
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16
المصدر: Biochemical and Biophysical Research Communications. 391:692-697
مصطلحات موضوعية: Proteases, Macrocyclic Compounds, Genotype, viruses, Hepatitis C virus, medicine.medical_treatment, Molecular Sequence Data, Biophysics, Hepacivirus, Viral Nonstructural Proteins, Biology, medicine.disease_cause, Antiviral Agents, Biochemistry, Viral Proteins, medicine, Humans, Protease Inhibitors, Amino Acid Sequence, Cloning, Molecular, Molecular Biology, Gene, Genetics, NS3, Protease, Intracellular Signaling Peptides and Proteins, RNA, Helicase, DNA, Cell Biology, Virology, Thiazoles, Quinolines, biology.protein, Carbamates, Carrier Proteins, RNA Helicases
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17
المؤلفون: Montse Llinas-Brunet, Diane Thibeault, Marie-Josée Massariol, Peter W. White, Ewald Welchner, Rock Gingras, Songping Zhao, Nathalie Goudreau
المصدر: Biochemistry. 48:744-753
مصطلحات موضوعية: Models, Molecular, Recombinant Fusion Proteins, viruses, medicine.medical_treatment, Molecular Sequence Data, Peptide, Hepacivirus, Viral Nonstructural Proteins, Biology, Crystallography, X-Ray, Biochemistry, Viral Proteins, Protein structure, medicine, Protease Inhibitors, Amino Acid Sequence, Peptide sequence, chemistry.chemical_classification, NS3, Protease, Serine Endopeptidases, Intracellular Signaling Peptides and Proteins, Protease inhibitor (biology), Protein Structure, Tertiary, Enzyme Activation, NS2-3 protease, chemistry, Carrier Proteins, Dimerization, RNA Helicases, MASP1, Protein Binding, medicine.drug
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18
المؤلفون: Mireille Cartier, Jean Rancourt, Anne-Marie Faucher, Marie-Josée Massariol, Peter W. White, Ewald Welchner, Jacques Archambault
المصدر: Antimicrobial Agents and Chemotherapy. 49:4834-4842
مصطلحات موضوعية: medicine.drug_class, ATPase, Allosteric regulation, Acetates, Antiviral Agents, Structure-Activity Relationship, Adenosine Triphosphate, Allosteric Regulation, medicine, Humans, Pharmacology (medical), Sulfones, Enzyme Inhibitors, Tyrosine, Papillomaviridae, Pharmacology, chemistry.chemical_classification, biology, Drug discovery, Hydrolysis, Biphenyl Compounds, Helicase, Oncogene Proteins, Viral, Infectious Diseases, Enzyme, Mechanism of action, Biochemistry, chemistry, biology.protein, medicine.symptom, Antiviral drug
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19
المؤلفون: Lisette Lagacé, Daniel Lamarre, Roger Maurice, Rock Gingras, Diane Thibeault, Christiane Bousquet, Peter W. White
المصدر: Journal of Virology. 78:7352-7359
مصطلحات موضوعية: Models, Molecular, Proteases, Macrocyclic Compounds, Serine Proteinase Inhibitors, Genotype, Hepatitis C virus, Hepacivirus, Molecular Sequence Data, Immunology, Replication, Microbial Sensitivity Tests, Viral Nonstructural Proteins, medicine.disease_cause, Antiviral Agents, Microbiology, Virus, Serine, Virology, Escherichia coli, medicine, Humans, Amino Acid Sequence, chemistry.chemical_classification, NS3, Binding Sites, biology, biology.organism_classification, Molecular biology, Kinetics, Thiazoles, Enzyme, chemistry, Insect Science, Mutation, Quinolines, Carbamates
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20
المؤلفون: David M Hambly, Christiane Yoakim, Peter W. White, Jerry L. Hopkins, Jacques Archambault, Graham A. McGibbon, William W. Ogilvie, Ingrid Guse, Walter Davidson, Lee Frego, Pierre Lavallee
المصدر: Analytical Chemistry. 76:2095-2102
مصطلحات موضوعية: Transcriptional Activation, Photoaffinity Labels, Crystallography, X-Ray, Antiviral Agents, Mass Spectrometry, Analytical Chemistry, Benzophenones, Viral Proteins, chemistry.chemical_compound, Transactivation, Protein structure, medicine, Humans, Trypsin, Enzyme Inhibitors, Binding site, Papillomaviridae, Binding Sites, biology, Photoaffinity labeling, DNA replication, Helicase, Recombinant Proteins, Protein Structure, Tertiary, DNA-Binding Proteins, chemistry, Biochemistry, biology.protein, DNA, medicine.drug