المؤلفون: Ameera Mohammed Dawoodjee, John Sichinga, Harrison Banda, Steve Mbaya, Evelyn Funjika, Godfrey Mayoka, Christabel Hikaambo, Karol R. Francisco, Yujie Uli Sun, Lawrence J. Liu, Conor R. Caffrey, Peter Mubanga Cheuka

المصدر: Results in Chemistry, Vol 12, Iss , Pp 101890- (2024)

مصطلحات موضوعية: N-phenylbenzamide analogs, N-pyridazinylbenzamide analogs, Schistosoma mansoni, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211715624005861; https://doaj.org/toc/2211-7156

URL الوصول: https://doaj.org/article/79d0dd0602cc48f4b4d7c306a5f0ed47

المؤلفون: Peter Mubanga Cheuka, Godfrey Mayoka, Peggoty Mutai, Kelly Chibale

المصدر: Molecules, Vol 22, Iss 1, p 58 (2016)

مصطلحات موضوعية: human African trypanosomiasis, leishmaniasis, schistosomiasis, lymphatic filariasis, natural products, antiprotozoal agents, phytotherapy, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1420-3049/22/1/58; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/37947e461f15458d816b43043d2ffd69

المؤلفون: Godfrey Mayoka, Peter Mubanga Cheuka

المصدر: African Journal of Pharmaceutical Sciences, 3(1), 14-30, (2023-03-05)

مصطلحات موضوعية: Traditional medicine, Alternative medicine, Safety, Efficacy, Pharmacotherapy, Herb-drug interactions

Relation: oai:zenodo.org:8116327

الاتاحة: https://doi.org/10.51483/AFJPS.3.1.2023.14-30

المؤلفون: Peter Mubanga Cheuka, Paul Njaria, Godfrey Mayoka, Evelyn Funjika

مصطلحات موضوعية: Biochemistry, Medicine, Genetics, Pharmacology, Biotechnology, Cancer, Infectious Diseases, Virology, Computational Biology, Biological Sciences not elsewhere classified, Physical Sciences not elsewhere classified, underlying chemical interactions, parasite mutations responsible, outlined mechanistic details, identify alternative treatments, function approximately 619, design appropriate inhibitors, cyclic guanosine monophosphate, antimalarial drug discovery, 000 malaria deaths, plasmodium falciparum <, including enzymes involved, emerging drug targets, n <, including artemisinin, urgent need, treatment failure, targets discussed, rna metabolism, recommended drugs

Relation: https://figshare.com/articles/dataset/Emerging_Drug_Targets_for_Antimalarial_Drug_Discovery_Validation_and_Insights_into_Molecular_Mechanisms_of_Function/24977520

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01828.s001
https://figshare.com/articles/dataset/Emerging_Drug_Targets_for_Antimalarial_Drug_Discovery_Validation_and_Insights_into_Molecular_Mechanisms_of_Function/24977520

المؤلفون: Peter Mubanga Cheuka, Dickson Mambwe, Godfrey Mayoka

المصدر: Current Topics in Medicinal Chemistry. 23:227-247

مصطلحات موضوعية: Drug Discovery, General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d731dd5eb850d9dd4603d566f07e347
https://doi.org/10.2174/1568026623666221220140526

المؤلفون: Masebe Kanyanta, Chilufya Lengwe, Dickson Mambwe, Karol R. Francisco, Lawrence J. Liu, Yujie Uli Sun, Dilini K. Amarasinghe, Conor R. Caffrey, Peter Mubanga Cheuka

المصدر: Bioorg Med Chem Lett

مصطلحات موضوعية: Organic Chemistry, Clinical Biochemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Molecular Biology, Biochemistry, Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da819e8d998a6b8f54e3652c6cef882
https://europepmc.org/articles/PMC10072318/

المؤلفون: Janette Reader, Kelly Chibale, Mariëtte van der Watt, Lyn-Marie Birkholtz, Henrico Langeveld, Peter Mubanga Cheuka, Godwin Akpeko Dziwornu, Dina Coertzen, Meta Leshabane

المصدر: Transactions of the Royal Society of South Africa. 76:225-233

مصطلحات موضوعية: Chemistry, General Earth and Planetary Sciences, General Medicine, General Agricultural and Biological Sciences, Combinatorial chemistry, Transmission blocking, General Environmental Science

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f3e62252a9c125413adfd2f5da4f361c
https://doi.org/10.1080/0035919x.2021.1982792

المؤلفون: Sergio Wittlin, Lynn Wambua, Luyanda Centani, Lauren B. Arendse, Lyn-Marie Birkholtz, Dale Taylor, Kelly Chibale, Janette Reader, Dina Coertzen, Nina Lawrence, Malkeet Kumar, Shoneeze S Renga, Peter Mubanga Cheuka, Stephen Fienberg, Godwin Akpeko Dziwornu, Mariëtte van der Watt

المصدر: ACS Infectious Diseases. 7:34-46

مصطلحات موضوعية: 0301 basic medicine, biology, Chemistry, Kinase, 030106 microbiology, hERG, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, Infectious Diseases, Biochemistry, In vivo, biology.protein, Phosphatidylinositol, Protein kinase A, cGMP-dependent protein kinase, Adenosine triphosphate, IC50

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::df75b11c41574c2c365ab07859345b41
https://doi.org/10.1021/acsinfecdis.0c00481

المؤلفون: Kelly Chibale, Peter Mubanga Cheuka, Godwin Akpeko Dziwornu, John Okombo

المصدر: Journal of Medicinal Chemistry. 63:4445-4467

مصطلحات موضوعية: Drug, Cellular activity, Proteases, Chemistry, Pharmaceutical, media_common.quotation_subject, Plasmodium falciparum, Protozoan Proteins, Plasmepsin, Computational biology, 01 natural sciences, Antimalarials, Mice, Structure-Activity Relationship, 03 medical and health sciences, Parasitic Sensitivity Tests, Aspartate protease, In vivo, Drug Discovery, Animals, Aspartic Acid Endopeptidases, Humans, Protease Inhibitors, 030304 developmental biology, media_common, 0303 health sciences, Molecular Structure, Drug discovery, Chemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Molecular Medicine, Peptidomimetics, Drug metabolism

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1ee872b2586f7fc8bf9a72738b1d3b
https://doi.org/10.1021/acs.jmedchem.9b01622

المؤلفون: Peter Mubanga Cheuka

المصدر: Current topics in medicinal chemistry. 22(19)

مصطلحات موضوعية: Drug, medicine.medical_specialty, media_common.quotation_subject, Schistosomiasis, Praziquantel, chemistry.chemical_compound, Mice, Drug Discovery, medicine, Animals, Humans, Metrifonate, Intensive care medicine, media_common, business.industry, Drug discovery, General Medicine, medicine.disease, Oxamniquine, Clinical trial, chemistry, Schistosoma, Identification (biology), business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f1ac4d095d1fc10a496b796cf980ff0
https://pubmed.ncbi.nlm.nih.gov/34565320

المؤلفون: Lokadi Pierre Luhata, Peter Mubanga Cheuka

مصطلحات موضوعية: Phytomedicine, Phytochemistry, Traditional medicine, Phytochemical, Genus, Odontonema, fungi, Acanthaceae, Plant species, food and beverages, Child birth, Biology, biology.organism_classification

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3ffe06df31213525bba8ae52acc69d2c
https://doi.org/10.9734/bpi/tipr/v1/2261e

المؤلفون: Peter Mubanga, Cheuka, Luyanda, Centani, Lauren B, Arendse, Stephen, Fienberg, Lynn, Wambua, Shoneeze S, Renga, Godwin Akpeko, Dziwornu, Malkeet, Kumar, Nina, Lawrence, Dale, Taylor, Sergio, Wittlin, Dina, Coertzen, Janette, Reader, Mariette, van der Watt, Lyn-Marie, Birkholtz, Kelly, Chibale

المصدر: ACS infectious diseases. 7(1)

مصطلحات موضوعية: Plasmodium, Plasmodium falciparum, Cyclic GMP-Dependent Protein Kinases, Phosphatidylinositols, 1-Phosphatidylinositol 4-Kinase, Protein Kinases, Guanidine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::5b31d5f4d31b055cbf9d3b039fa31aaf
https://pubmed.ncbi.nlm.nih.gov/33319990

المؤلفون: Dale Taylor, Peter Mubanga Cheuka, Kelly Chibale, Sergio Wittlin, Nina Lawrence

المصدر: MedChemComm. 9:1733-1745

مصطلحات موضوعية: Pharmacology, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, hERG, Pharmaceutical Science, 01 natural sciences, Biochemistry, In vitro, 0104 chemical sciences, Multiple drug resistance, 010404 medicinal & biomolecular chemistry, In vivo, Drug Discovery, biology.protein, Molecular Medicine, Potency, Structure–activity relationship, Solubility, IC50

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005a9122ad0e6cae93528f1aff548e12
https://doi.org/10.1039/c8md00382c

المؤلفون: Peter Mubanga Cheuka, Kelly Chibale, Godfrey Mayoka, John Okombo

مصطلحات موضوعية: biology, business.industry, Drug discovery, Plasmodium falciparum, Bioinformatics, medicine.disease, biology.organism_classification, 01 natural sciences, Phenotype, World health, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Chloroquine, Medicine, business, Whole cell, Malaria, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4873fb91bd4e52887fdba8779a4953b0
https://doi.org/10.1016/bs.armc.2019.04.001

المؤلفون: Susan A. Bourne, Terence J. Noonan, Mino R. Caira, Peter Mubanga Cheuka, Kelly Chibale

المصدر: Journal of pharmaceutical sciences. 108(7)

مصطلحات موضوعية: Fumaric acid, Pyridines, Adipates, Pharmaceutical Science, 02 engineering and technology, Glutaric acid, Malonic acid, Sodium Chloride, Crystallography, X-Ray, 030226 pharmacology & pharmacy, Cocrystal, Glutarates, 03 medical and health sciences, chemistry.chemical_compound, Antimalarials, 0302 clinical medicine, Fumarates, X-Ray Diffraction, parasitic diseases, Plasmodium berghei, Dicarboxylic Acids, Solubility, chemistry.chemical_classification, Adipic acid, biology, Imidazoles, 021001 nanoscience & nanotechnology, biology.organism_classification, Combinatorial chemistry, Malonates, Dicarboxylic acid, chemistry, 0210 nano-technology, Crystallization, Powder Diffraction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcfe8df0e25b457e1119ff7f14a19f9b
https://pubmed.ncbi.nlm.nih.gov/30817923

المؤلفون: Harrison Sikanyika, Namboole Moses Munkombwe, Peter Mubanga Cheuka, Lokadi Pierre Luhata

المصدر: British Journal of Pharmaceutical Research. 14:1-7

مصطلحات موضوعية: Phytomedicine, Phytochemistry, biology, Traditional medicine, Phytochemical, Genus, Odontonema, Botany, Plant species, Acanthaceae, Child birth, General Medicine, biology.organism_classification

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cf7efbdfbcce89d3533a93c3e0f471a7
https://doi.org/10.9734/bjpr/2016/29877

المؤلفون: Diego Gonzàlez Cabrera, Tanya Paquet, Peter Mubanga Cheuka, Kelly Chibale

المصدر: Bioorganic & Medicinal Chemistry Letters. 24:5207-5211

مصطلحات موضوعية: Stereochemistry, medicine.drug_class, Plasmodium falciparum, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Pyrazole, Biochemistry, Antimalarials, Mice, Structure-Activity Relationship, chemistry.chemical_compound, parasitic diseases, Drug Discovery, medicine, Animals, Parasite hosting, Structure–activity relationship, Molecular Biology, IC50, biology, Strain (chemistry), Organic Chemistry, biology.organism_classification, In vitro, Thiazoles, chemistry, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98f5e20cbc94fd5eed76ca796c9a069
https://doi.org/10.1016/j.bmcl.2014.09.071

المؤلفون: Kelly Chibale, Peter Mubanga Cheuka, Godfrey Mayoka, Peggoty Mutai

المصدر: Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 22, Iss 1, p 58 (2016)

مصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, Tuberculosis, natural products, human African trypanosomiasis, 030231 tropical medicine, Antiprotozoal Agents, Pharmaceutical Science, Drug resistance, Review, Analytical Chemistry, lcsh:QD241-441, 03 medical and health sciences, 0302 clinical medicine, Elephantiasis, Filarial, lcsh:Organic chemistry, Environmental health, schistosomiasis, Drug Discovery, medicine, Humans, African trypanosomiasis, Physical and Theoretical Chemistry, Adverse effect, lymphatic filariasis, Leishmaniasis, Lymphatic filariasis, Biological Products, business.industry, Organic Chemistry, phytotherapy, Neglected Diseases, medicine.disease, Biotechnology, 030104 developmental biology, Pharmaceutical care, Trypanosomiasis, African, Chemistry (miscellaneous), Neglected tropical diseases, Molecular Medicine, Plant Preparations, business, Malaria

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95d5fcb9bc9e81c5e19d0baf75e04e90
http://europepmc.org/articles/PMC6155950