المؤلفون: Matthew C. L. Wakeham (11836887), Briana J. Davie (11836890), David K. Chalmers (1455451), Arthur Christopoulos (538751), Ben Capuano (1435147), Celine Valant (1583104), Peter J. Scammells (694050)

مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Pharmacology, Biotechnology, Evolutionary Biology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, muscarinic acetylcholine receptors, machr responses compared, restoring nonselective agonism, methoxybenzyl )- 4, ligands possessed noticeable, possible allosteric interaction, machr selective agonists, machr subtypes suggests, 1 -( 4, 4 , efficacy selective agonists, 1 , 5 , selective agonism, machr subtypes, n <, hybrid ligands, allosteric site, allosteric pharmacophore, machr selectivity

Relation: https://figshare.com/articles/journal_contribution/Structural_Features_of_Iperoxo_BQCA_Muscarinic_Acetylcholine_Receptor_Hybrid_Ligands_Determining_Subtype_Selectivity_and_Efficacy/17203743

الاتاحة: https://doi.org/10.1021/acschemneuro.1c00572.s001

المؤلفون: Eleonora Comeo (8270664), Phuc Trinh (10312494), Anh T. Nguyen (7865891), Cameron J. Nowell (735904), Nicholas D. Kindon (2393749), Mark Soave (8270667), Leigh A. Stoddart (1451152), Jonathan M. White (1366602), Stephen J. Hill (481670), Barrie Kellam (1280532), Michelle L. Halls (1372671), Lauren T. May (1684459), Peter J. Scammells (694050)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Inorganic Chemistry, Infectious Diseases, Plant Biology, Computational Biology, Chemical Sciences not elsewhere classified, equilibrium ligand binding parameters, functionalized, series, receptor distribution patterns, 1 AR, understanding, TIRF, 1-yl xanthine scaffolds, 1 AR pharmacology, 1 AR-selective, GPCR

Relation: https://figshare.com/articles/journal_contribution/Development_and_Application_of_Subtype-Selective_Fluorescent_Antagonists_for_the_Study_of_the_Human_Adenosine_A_sub_1_sub_Receptor_in_Living_Cells/14224290

الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c02067.s001

المؤلفون: Eleonora Comeo (8270664), Phuc Trinh (10312494), Anh T. Nguyen (7865891), Cameron J. Nowell (735904), Nicholas D. Kindon (2393749), Mark Soave (8270667), Leigh A. Stoddart (1451152), Jonathan M. White (1366602), Stephen J. Hill (481670), Barrie Kellam (1280532), Michelle L. Halls (1372671), Lauren T. May (1684459), Peter J. Scammells (694050)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Inorganic Chemistry, Infectious Diseases, Plant Biology, Computational Biology, Chemical Sciences not elsewhere classified, equilibrium ligand binding parameters, functionalized, series, receptor distribution patterns, 1 AR, understanding, TIRF, 1-yl xanthine scaffolds, 1 AR pharmacology, 1 AR-selective, GPCR

Relation: https://figshare.com/articles/dataset/Development_and_Application_of_Subtype-Selective_Fluorescent_Antagonists_for_the_Study_of_the_Human_Adenosine_A_sub_1_sub_Receptor_in_Living_Cells/14224293

الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c02067.s002