المؤلفون: Taeyoung Hwang, Dimitrios Mathios, Kerrie L. McDonald, Irene Daris, Sung-Hye Park, Peter C. Burger, Sojin Kim, Yun-Sik Dho, Hruban Carolyn, Chetan Bettegowda, Joo Heon Shin, Michael Lim, Chul-Kee Park

المصدر: Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-12 (2019)

مصطلحات موضوعية: Glioblastoma, Long-term survivor, DNA methylation, Genome-wide analyses, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-019-0744-0; https://doaj.org/toc/2051-5960

URL الوصول: https://doaj.org/article/6b54e677e8cf472dbbb96b9facdc5ed2

المؤلفون: Michael Lim, Drew M. Pardoll, Henry Brem, Charles G. Drake, Peter C. Burger, Janis M. Taube, Alessandro Olivi, Xiaobu Ye, Phuoc T. Tran, Betty M. Tyler, Allison M. Martin, Mary Sheu, Tomas Garzon-Muvdi, Sarah Harris-Bookman, Christopher M. Jackson, Dimitrios Mathios, Haiying Xu, Ada Tam, Eric W. Sankey, Ann Liu, Esteban Velarde, Debebe Theodros, Eileen S. Kim, Antonella Mangraviti, Mira A. Patel, Jennifer E. Kim

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::940e2d4f691293cd70905de34e5425d2
https://doi.org/10.1158/1078-0432.22458344

المؤلفون: Michael Lim, Drew M. Pardoll, Henry Brem, Charles G. Drake, Peter C. Burger, Janis M. Taube, Alessandro Olivi, Xiaobu Ye, Phuoc T. Tran, Betty M. Tyler, Allison M. Martin, Mary Sheu, Tomas Garzon-Muvdi, Sarah Harris-Bookman, Christopher M. Jackson, Dimitrios Mathios, Haiying Xu, Ada Tam, Eric W. Sankey, Ann Liu, Esteban Velarde, Debebe Theodros, Eileen S. Kim, Antonella Mangraviti, Mira A. Patel, Jennifer E. Kim

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ced1dd5f4abdff56ee0b295de0e6ab1
https://doi.org/10.1158/1078-0432.22458347.v1

المؤلفون: Michael Lim, Drew M. Pardoll, Henry Brem, Charles G. Drake, Peter C. Burger, Janis M. Taube, Alessandro Olivi, Xiaobu Ye, Phuoc T. Tran, Betty M. Tyler, Allison M. Martin, Mary Sheu, Tomas Garzon-Muvdi, Sarah Harris-Bookman, Christopher M. Jackson, Dimitrios Mathios, Haiying Xu, Ada Tam, Eric W. Sankey, Ann Liu, Esteban Velarde, Debebe Theodros, Eileen S. Kim, Antonella Mangraviti, Mira A. Patel, Jennifer E. Kim

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2853921deec37136f0c6eb62d9996a96
https://doi.org/10.1158/1078-0432.c.6523910

المؤلفون: Michael Lim, Drew M. Pardoll, Henry Brem, Charles G. Drake, Peter C. Burger, Janis M. Taube, Alessandro Olivi, Xiaobu Ye, Phuoc T. Tran, Betty M. Tyler, Allison M. Martin, Mary Sheu, Tomas Garzon-Muvdi, Sarah Harris-Bookman, Christopher M. Jackson, Dimitrios Mathios, Haiying Xu, Ada Tam, Eric W. Sankey, Ann Liu, Esteban Velarde, Debebe Theodros, Eileen S. Kim, Antonella Mangraviti, Mira A. Patel, Jennifer E. Kim

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061736f9093c8f6342ecc15d19c76998
https://doi.org/10.1158/1078-0432.22458341

المؤلفون: Michael Lim, Drew M. Pardoll, Henry Brem, Charles G. Drake, Peter C. Burger, Janis M. Taube, Alessandro Olivi, Xiaobu Ye, Phuoc T. Tran, Betty M. Tyler, Allison M. Martin, Mary Sheu, Tomas Garzon-Muvdi, Sarah Harris-Bookman, Christopher M. Jackson, Dimitrios Mathios, Haiying Xu, Ada Tam, Eric W. Sankey, Ann Liu, Esteban Velarde, Debebe Theodros, Eileen S. Kim, Antonella Mangraviti, Mira A. Patel, Jennifer E. Kim

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec22dcf3cb150069ac8da42c94e2bab
https://doi.org/10.1158/1078-0432.22458350.v1

المؤلفون: Michael Lim, Drew M. Pardoll, Henry Brem, Charles G. Drake, Peter C. Burger, Janis M. Taube, Alessandro Olivi, Xiaobu Ye, Phuoc T. Tran, Betty M. Tyler, Allison M. Martin, Mary Sheu, Tomas Garzon-Muvdi, Sarah Harris-Bookman, Christopher M. Jackson, Dimitrios Mathios, Haiying Xu, Ada Tam, Eric W. Sankey, Ann Liu, Esteban Velarde, Debebe Theodros, Eileen S. Kim, Antonella Mangraviti, Mira A. Patel, Jennifer E. Kim

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272554deb440490aa41a9aa1cde2a2fd
https://doi.org/10.1158/1078-0432.22458338.v1

المؤلفون: Mari L. Groves, Jean Paul Wolinsky, Rajiv R. Iyer, Ann Liu, Fausto J. Rodriguez, Charles G. Eberhart, Tej D. Azad, George I. Jallo, Chetan Bettegowda, Joanna Wang, Peter C. Burger, Tomas Garzon-Muvdi, Ming Zhang, Daniel M. Sciubba, Qing Wang, Ziya L. Gokaslan

المصدر: Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports

مصطلحات موضوعية: Adult, Male, Ependymoma, Pathology, medicine.medical_specialty, Adolescent, Somatic cell, Central nervous system, Intramedullary spinal cord, lcsh:Medicine, Astrocytoma, Article, Germline, 03 medical and health sciences, 0302 clinical medicine, Exome Sequencing, Cancer genomics, medicine, Humans, Spinal Cord Neoplasms, lcsh:Science, Exome sequencing, Aged, 030304 developmental biology, Homeodomain Proteins, Neurofibromin 2, 0303 health sciences, Multidisciplinary, business.industry, lcsh:R, Genomics, Glioma, Middle Aged, Spinal cord, medicine.disease, 3. Good health, CNS cancer, medicine.anatomical_structure, Spinal Cord, Female, lcsh:Q, Glioblastoma, business, Microtubule-Associated Proteins, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0c5f73922afde6756206c2e9d9bf7e3
http://link.springer.com/article/10.1038/s41598-019-54286-9

المؤلفون: Joanna Wang, Tej D. Azad, Jean Paul Wolinsky, Ziya L. Gokaslan, Ann Liu, Fausto J. Rodriguez, Daniel M. Sciubba, Qing Wang, Peter C. Burger, Tomas Garzon-Muvdi, Charles G. Eberhart, Ming Zhang, Rajiv R. Iyer

المصدر: Neurosurgery. 66:310-332

مصطلحات موضوعية: Ependymoma, Pathology, medicine.medical_specialty, business.industry, Spinal Cord Neoplasm, Central nervous system, Intramedullary spinal cord, Astrocytoma, medicine.disease, Ganglioglioma, medicine.anatomical_structure, medicine, Surgery, Neurology (clinical), Oligodendroglioma, business, Glioblastoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::328a10888b059e171c05423779476856
https://doi.org/10.1093/neuros/nyz310_332

المؤلفون: Taeyoung Hwang, Peter C. Burger, Victor E. Velculescu, Zineb Belcaid, Russell Maxwell, Leslie Cope, Drew M. Pardoll, Alfred P. See, Chul-Kee Park, Gary L. Gallia, Mihoko Kai, Yuan Rui, Michael Lim, Henry Brem, Chetan Bettegowda, Patrick K. Ha, Joshua Casaos, Yuanxuan Xia, Jordan J. Green, Jillian Phallen, Dimitrios Mathios, Kerrie L. McDonald

المصدر: International Journal of Cancer. 145:3425-3435

مصطلحات موضوعية: Cancer Research, Transcription, Genetic, Mice, Nude, Biology, Genome, Epigenesis, Genetic, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Movement, Cell Line, Tumor, Molecular marker, Biomarkers, Tumor, medicine, Animals, Epigenetics, Promoter Regions, Genetic, Gene, Brain Neoplasms, Cancer, Promoter, Methylation, DNA Methylation, Prognosis, medicine.disease, Gene Expression Regulation, Neoplastic, Oncology, chemistry, 030220 oncology & carcinogenesis, DNA methylation, Cancer research, Female, Glioblastoma, Genome-Wide Association Study, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e73c433462bab0757fa25b1166f605a7
https://doi.org/10.1002/ijc.32587

المؤلفون: Linda Heier, Jeff M. Michalski, Leanne Embry, Yimei Li, Amar Gajjar, Karin S. Walsh, Kyle S. Smith, Alok Jaju, Roger J. Packer, Sarah Leary, James M. Olson, Maryam Fouladi, Jennifer Hadley, Catherine A. Billups, Eugene Hwang, Paul A. Northcott, Peter C. Burger, Ian F. Pollack, Yuanyuan Han, Rahul Kumar

المصدر: JAMA Oncol

مصطلحات موضوعية: Oncology, Cancer Research, Vincristine, medicine.medical_specialty, Randomization, Subgroup analysis, law.invention, chemistry.chemical_compound, Randomized controlled trial, law, Internal medicine, medicine, Biomarkers, Tumor, Humans, Cerebellar Neoplasms, Isotretinoin, Original Investigation, Medulloblastoma, business.industry, Gene Expression Profiling, medicine.disease, Carboplatin, Clinical trial, chemistry, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6450a775c0a26cfad724e1e171bf7cb5
https://europepmc.org/articles/PMC8299367/

المؤلفون: Catherine A. Billups, Timothy N. Booth, Paul A. Northcott, Stephanie M. Perkins, Jeff M. Michalski, Roger J. Packer, Karin M. Muraszko, Yimei Li, Kristina K. Hardy, Paul Colte, Yuanyuan Han, Rahul Kumar, Kyle S. Smith, Anna J. Janss, L. Gilbert Vezina, Nancy J. Tarbell, Leanne Embry, Maryam Fouladi, Peter C. Burger, Ian F. Pollack, Joel M. Cherlow, Johnnie K. Bass, Amar Gajjar, Patricia Cullen, Thomas J. Fitzgerald, Scott L. Pomeroy, Thomas E. Merchant, Jennifer Hadley

المصدر: J Clin Oncol

مصطلحات موضوعية: Oncology, Adult, Male, Cancer Research, medicine.medical_specialty, Adolescent, medicine.medical_treatment, Newly diagnosed, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Child, Medulloblastoma, Average risk, Chemotherapy, business.industry, ORIGINAL REPORTS, medicine.disease, Reduced dose, Radiation therapy, 030220 oncology & carcinogenesis, Child, Preschool, Female, business, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc80b4222efce4c088ab45e139955e5a
https://pubmed.ncbi.nlm.nih.gov/34110925

المؤلفون: Menghang Xia, Adrienne M. Flanagan, Tianna Zhao, Gary L. Gallia, Chenchen Ji, Jacob Ruzevick, Peter C. Burger, I-Mei Siu, Nick Connis, Haoyu Zhang, Tara Williamson, Lucia Cottone, Christine L. Hann

المصدر: J Pathol

مصطلحات موضوعية: musculoskeletal diseases, Afatinib, Morpholines, Article, Pathology and Forensic Medicine, Mice, In vivo, Antineoplastic Combined Chemotherapy Protocols, medicine, Chordoma, Animals, Humans, Viability assay, PI3K/AKT/mTOR pathway, Cell Proliferation, Crizotinib, business.industry, Drug Synergism, medicine.disease, Xenograft Model Antitumor Assays, Cell culture, Cancer research, Erlotinib, Drug Screening Assays, Antitumor, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f20d68d4a99fc9e8bd760c5960e65cdb
https://pubmed.ncbi.nlm.nih.gov/34124783

المؤلفون: Riccardo Serra, Tianna Zhao, Peter C. Burger, Michelle Guo, Gary L. Gallia, Christine L. Hann, Lisa M. Rooper, Betty Tyler

المصدر: Special Virtual Symposium of the North American Skull Base Society.

مصطلحات موضوعية: biology, Cyclin-dependent kinase, In vivo, Chemistry, Egfr inhibition, biology.protein, Cancer research, Blockade

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4df0ee6575b5713de8340638355dbd80
https://doi.org/10.1055/s-0041-1725264

المؤلفون: Christelle Dufour, Johannes Gojo, Sandra Jacobs, Barry Pizer, Dominik Sturm, Torsten Pietsch, Stefan Rutkowski, Christine Haberler, Nicolas U. Gerber, Teresa de Rojas, Peter Hauser, Ulrich Schüller, Peter C. Burger, Marta Perek-Polnik, Martin Mynarek, Jaeho Cho, Matija Snuderl, Bernward Zeller, Michal Zapotocky, Maura Massimino, Robert Kwiecien, Dominique Figarella-Branger, Andrey Golanov, Charles G. Eberhart, Stefan M. Pfister, Daniel Alderete, Thomas S. Jacques, Ella Kumirova, Konstantin Okonechnikov, Astrid Sehested, Ofelia Cruz, Andrey Korshunov, Björn Ole Juhnke, Niels Bovenschen, Jessica C Pickles, David Sumerauer, Cynthia Hawkins, David Scheie, Eugene Hwang, Pieter Wesseling, Barbara von Zezschwitz, Felice Giangaspero, Marcel Kool, Elizabeth Schepke, Andreas von Deimling, Marco Gessi, Dannis G. van Vuurden, Maximilian Wechsung, Miklós Garami, David Capper, Katja von Hoff, Maria Joao Gil-da-Costa, Maria Łastowska, Felix Schmitt-Hoffner, Olga Zheludkova, Lucas Moreno, Michael A. Grotzer, Frank Konietschke, Marina Ryzhova, Elisabeth J. Rushing, Irene Slavc

المساهمون: Institut de neurophysiopathologie (INP), Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU), Laboratoire d'Anatomie Pathologique-Neuropathologique [AP-HM Hôpital La Timone], Hôpital de la Timone [CHU - APHM] (TIMONE), Pediatric surgery, CCA - Imaging and biomarkers, CCA - Cancer Treatment and quality of life, Pathology, Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Neuro-Oncology 23(9), 1597-1611 (2021). doi:10.1093/neuonc/noab136
Neuro-Oncology
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
Neuro-Oncology, Oxford University Press (OUP), 2021, ⟨10.1093/neuonc/noab136⟩
Neuro-Oncology, 23(9), 1597-1611. Oxford University Press
von Hoff, K, Haberler, C, Schmitt-Hoffner, F, Schepke, E, de Rojas, T, Jacobs, S, Zapotocky, M, Sumerauer, D, Perek-Polnik, M, Dufour, C, van Vuurden, D, Slavc, I, Gojo, J, Pickles, J C, Gerber, N U, Massimino, M, Gil-da-Costa, M J, Garami, M, Kumirova, E, Sehested, A, Scheie, D, Cruz, O, Moreno, L, Cho, J, Zeller, B, Bovenschen, N, Grotzer, M, Alderete, D, Snuderl, M, Zheludkova, O, Golanov, A, Okonechnikov, K, Mynarek, M, Juhnke, B O, Rutkowski, S, Schüller, U, Pizer, B, von Zezschwitz, B, Kwiecien, R, Wechsung, M, Konietschke, F, Hwang, E I, Sturm, D, Pfister, S M, von Deimling, A, Rushing, E J, Ryzhova, M, Hauser, P, Łastowska, M, Wesseling, P, Giangaspero, F, Hawkins, C, Figarella-Branger, D, Eberhart, C, Burger, P, Gessi, M, Korshunov, A, Jacques, T S, Capper, D, Pietsch, T & Kool, M 2021, ' Therapeutic implications of improved molecular diagnostics for rare CNS embryonal tumor entities : Results of an international, retrospective study ', Neuro-Oncology, vol. 23, no. 9, pp. 1597-1611 . https://doi.org/10.1093/neuonc/noab136
Neuro Oncol
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
Neuro-Oncology, 2021, ⟨10.1093/neuonc/noab136⟩

مصطلحات موضوعية: Oncology, Cancer Research, genetics [Central Nervous System Neoplasms], medicine.medical_treatment, [SDV]Life Sciences [q-bio], diagnosis [Central Nervous System Neoplasms], Central Nervous System Neoplasms, 0302 clinical medicine, CNS-PNET, Medicine, Neuroectodermal Tumors, Primitive, genetics [Neoplasms, Germ Cell and Embryonal], Pathology, Molecular, diagnosis [Brain Neoplasms], Brain Neoplasms, genetics [Neuroectodermal Tumors, Primitive], CNS embryonal tumor, Forkhead Transcription Factors, Neoplasms, Germ Cell and Embryonal, 3. Good health, therapy [Brain Neoplasms], therapy [Neoplasms, Germ Cell and Embryonal], 030220 oncology & carcinogenesis, DNA methylation, DNA methylation profiling, therapy [Central Nervous System Neoplasms], medicine.medical_specialty, CNS NB-FOXR2, ETMR, FOXR2 protein, human, 03 medical and health sciences, Glioma, Internal medicine, Neuroblastoma, Humans, ddc:610, diagnosis [Neuroectodermal Tumors, Primitive], Retrospective Studies, Chemotherapy, business.industry, Retrospective cohort study, medicine.disease, Molecular diagnostics, therapy [Neuroectodermal Tumors, Primitive], genetics [Brain Neoplasms], CNS Embryonal Tumor, Regimen, diagnosis [Neoplasms, Germ Cell and Embryonal], Neurology (clinical), business, Pediatric Neuro-Oncology, 030217 neurology & neurosurgery

وصف الملف: Print

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cfda65d63cf766e727aec652e64d395

المؤلفون: I-Mei Siu, Jacob Ruzevick, Qi Zhao, Nick Connis, Yuchen Jiao, Chetan Bettegowda, Xuewei Xia, Peter C Burger, Christine L Hann, Gary L Gallia

المصدر: PLoS ONE, Vol 8, Iss 11, p e78895 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3829812?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/6730dfb885de47f5b56a2e97daee58b1

المؤلفون: Alyssa Reddy, Anita Mahajan, Timothy N. Booth, Chris Williams-Hughes, Peter C. Burger, Ian F. Pollack, Maryam Fouladi, Tianni Zhou, Alexander R. Judkins, Douglas Strother, Louis Gilbert Vezina, Annie Huang, Ben Ho, Victor Lewis, Allen Buxton, Mark Krailo, Claire Mazewski

المصدر: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 38(28)

مصطلحات موضوعية: Central Nervous System Neoplasms, Cancer Research, Radiation, Oncology, business.industry, MEDLINE, Library science, Medicine, Humans, business, Child, Rhabdoid Tumor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48338932995722c70ad5237300769ce1
https://pubmed.ncbi.nlm.nih.gov/32730182

المؤلفون: Marcel Kool, Sebastian Brabetz, Maryam Fouladi, Eugene Hwang, David T.W. Jones, Linda Heier, Jeff M. Michalski, Chris Williams-Hughes, Lukas Chavez, Alok Jaju, David Capper, Peter C. Burger, James M. Olson, Ian F. Pollack, Stefan M. Pfister, Roger J. Packer, Catherine A. Billups, Yimei Li, Andreas von Deimling, Amar Gajjar, Sarah Leary, Tianni Zhou

المصدر: J Clin Oncol

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Cns pnet, Population, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Single entity, Internal medicine, medicine, In patient, education, Isotretinoin, Pineoblastoma, Medulloblastoma, education.field_of_study, business.industry, ORIGINAL REPORTS, medicine.disease, Carboplatin, chemistry, 030220 oncology & carcinogenesis, business, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7dc1d69d5aa03d2c5b30064a9c1c57
https://doi.org/10.1200/jco.2017.76.4720

المؤلفون: Fausto J. Rodriguez, Aparna Pallavajjala, Doreen N. Palsgrove, Ming Yuan, Peter C. Burger, Eibar Ernesto Cabrera-Aldana, M. Adelita Vizcaino, Caterina Giannini

المصدر: Brain Pathology. 29:193-204

مصطلحات موضوعية: 0301 basic medicine, Pathology, medicine.medical_specialty, Monosomy, IDH1, biology, business.industry, General Neuroscience, Astrocytoma, medicine.disease, Pathology and Forensic Medicine, 03 medical and health sciences, Diffuse Glioma, 030104 developmental biology, 0302 clinical medicine, CDKN2A, Glioma, biology.protein, Medicine, PTEN, Neurology (clinical), business, 030217 neurology & neurosurgery, ATRX

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::10e68f512969f06438f2170f2e9fe0d3
https://doi.org/10.1111/bpa.12657

المؤلفون: Henry Brem, Peter C. Burger, Alan J. Korman, Sarah Harris-Bookman, Drew M. Pardoll, Allison Martin, Eileen Kim, Charles G. Drake, Zineb Belcaid, Jennifer E. Kim, Janis M. Taube, Xiaobu Ye, Yuanxuan Xia, Corina Taitt, Mark J. Selby, Dimitrios Mathios, Haiying Xu, Theresa Barberi, Magdalena J. Polanczyk, Debebe Theodros, Michael Lim

المصدر: International Journal of Cancer. 143:3201-3208

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.drug_class, business.industry, T cell, medicine.medical_treatment, Anti pd 1, Immunotherapy, Monoclonal antibody, medicine.disease, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Combined treatment, Oncology, Mouse Glioblastoma, 030220 oncology & carcinogenesis, Blocking antibody, medicine, Cancer research, business, Glioblastoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5135a95716041d8e123356406bd544e1
https://doi.org/10.1002/ijc.31661