المؤلفون: Chaurasiya, Vaishali, Pham, Dan Duc, Harju, Jukka, Juuti, Anne, Penttilä, Anne, Emmagouni, Sharath Kumar Goud, Nguyen, Van Dien, Zhang, Birong, Perttunen, Sanni, Keskitalo, Salla, Zhou, You, Pietiläinen, Kirsi H., Haridas, P. A. Nidhina, Olkkonen, Vesa M.

المساهمون: II kirurgian klinikka, HUS Abdominal Center, Department of Surgery, Clinicum, Institute of Biotechnology, Molecular Systems Biology, Helsinki Institute of Life Science HiLIFE, Joint Activities, Department of Medicine, Research Programs Unit, CAMM - Research Program for Clinical and Molecular Metabolism, Endokrinologian yksikkö, Medicum, Department of Anatomy

مصطلحات موضوعية: Cell isolation, Co-culture, Communication, Endothelial cell, Visceral adipose tissue, White adipocyte, Biomedicine

وصف الملف: application/pdf

Relation: We are grateful to Alexandre Santos, Tiisa Kalske, Anna-Maria Tholix, Antti Turunen, Henrik Husu, Henriikka Hietaniemi, Pauliina Reijonen, Tuula Ranta-Knuuttila, Minna Rasanen, Rohit Verma, Leo-pold Nelimarkka and Panu Aaltonen for providing the VAT biopsies of gallstone patients. Riikka Kosonen is thanked for expert technical assistance. This study was supported by the Academy of Finland (Grant 322647 to V.M.O.) , the Sigrid Juselius Foundation, the Magnus Ehrnrooth Foundation, the Finnish Diabetes Research Foundation (V.M.O) , the Ministry of Education in Finland (EDUFI grant to V.C.) , and the Yrjo Jahnsson Foundation (Grant 20227515 to V.C.) . KHP was supported by Academy of Finland (#272376, 266286, 314383, 335443) , Finnish Medical Foundation, Finnish Diabetes Research Foundation, Novo Nordisk Foundation (#NNF10OC1013354, NNF17OC0027232, NNF20OC006054) , Gyllenberg Foundation, Sigrid Juselius Foundation, Helsinki University Hospital Research Funds, Jalmari and Rauha Ahokas Foundation, Finnish Foundation for Cardiovascular Research, Government Research Funds, Helsinki University Hospital, and the University of Helsinki.r Nordisk Foundation (#NNF10OC1013354, NNF17OC0027232, NNF20OC006054) , Gyllenberg Foundation, Sigrid Juse lius Founda-tion, Helsinki University Hospital Research Funds, Jalmari and Rauha Ahokas Foundation, Finnish Foundation for Cardiovascular Research, Government Research Funds, Helsinki University Hospital, and the University of Helsinki.; http://hdl.handle.net/10138/587313; 85175493247; 001102283900001

الاتاحة: http://hdl.handle.net/10138/587313

المؤلفون: Wang, Hong, Siren, Juuso, Perttunen, Sanni, Immonen, Katariina, Chen, Yu-Chia, Narumanchi, Suneeta, Kosonen, Riikka, Paavola, Jere, Laine, Mika, Tikkanen, Ilkka, Lakkisto, Päivi

المساهمون: Medicum, HUS Musculoskeletal and Plastic Surgery, Faculty Common Matters (Faculty of Medicine), Helsinki Institute of Life Science HiLIFE, Infra, Department of Anatomy, HUS Heart and Lung Center, HUS Abdominal Center, Department of Medicine, Clinicum, Nefrologian yksikkö, HUSLAB, Department of Clinical Chemistry and Hematology, HUS Helsinki and Uusimaa Hospital District

مصطلحات موضوعية: cardiac hypertrophy, cardiac output, heme oxygenase 1, interstitial fibrosis, Biochemistry, cell and molecular biology

وصف الملف: application/pdf

Relation: We thank Daria Blokhina and Elina Ojala for assistance with the hypoxia assays. We acknowledge the Biomedicum Imaging Unit (BIU), Zebrafish Unit at the University of Helsinki, Tissue Preparation and Histochemistry Unit, and Genome Biology Unit for excellent technical assistance. The work was supported by grants from the Finnish Cultural Foundation (HW, SN, PL), the Finnish Foundation for Cardiovascular Research (HW, IT, PL), the Aarne Koskelo Foundation (HW, SN, IT, PL), Ida Montin Foundation (SN), the Finnish Foundation for Laboratory Medicine (PL), Finska Läkaresällskapet (IT, PL), the Liv och Hälsa Foundation (IT, PL), the Finnish Society of Clinical Chemistry (PL), Päivikki and Sakari Sohlberg Foundation (PL), and Finnish state funding for university‐level research (IT, PL). Open access funding was provided by University of Helsinki.; Wang , H , Siren , J , Perttunen , S , Immonen , K , Chen , Y-C , Narumanchi , S , Kosonen , R , Paavola , J , Laine , M , Tikkanen , I & Lakkisto , P 2024 , ' Deficiency of heme oxygenase 1a causes detrimental effects on cardiac function ' , Journal of Cellular and Molecular Medicine , vol. 28 , no. 7 , e18243 . https://doi.org/10.1111/jcmm.18243; ORCID: /0000-0001-5700-6786/work/158143027; ORCID: /0000-0001-9935-6573/work/158147448; http://hdl.handle.net/10138/574598; 00208075-90ef-4db0-80e1-b6065829546a; 85188278279; 001189864700009

الاتاحة: http://hdl.handle.net/10138/574598

المؤلفون: Narumanchi, Suneeta, Wang, Hong, Perttunen, Sanni, Tikkanen, Ilkka, Lakkisto, Päivi, Paavola, Jere

المصدر: Frontiers in Cell and Developmental Biology ; volume 9 ; ISSN 2296-634X

الاتاحة: http://dx.doi.org/10.3389/fcell.2021.662583
https://www.frontiersin.org/articles/10.3389/fcell.2021.662583/full

المؤلفون: Paavola, Jere, Alakoski, Tarja, Ulvila, Johanna, Kilpiö, Teemu, Sirén, Juuso, Perttunen, Sanni, Narumanchi, Suneeta, Wang, Hong, Lin, Ruizhu, Porvari, Katja, Junttila, Juhani, Huikuri, Heikki, Immonen, Katariina, Lakkisto, Päivi, Magga, Johanna, Tikkanen, Ilkka, Kerkelä, Risto

المساهمون: Medicum, HUSLAB, Department of Clinical Chemistry and Hematology, University of Helsinki, Department of Medicine, HUS Abdominal Center, Clinicum, Nefrologian yksikkö

مصطلحات موضوعية: Biomedicine, Vezf1, Cardiac hypertrophy, Cardiac contractile function, TEAD-1, ZEBRAFISH, ANGIOGENESIS, PERFORMANCE, HYPERTROPHY, ROLES, ENDOTHELIAL-CELLS, GROWTH, TRANSCRIPTION FACTOR, EXPRESSION, REQUIREMENT, General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

Relation: Paavola , J , Alakoski , T , Ulvila , J , Kilpiö , T , Sirén , J , Perttunen , S , Narumanchi , S , Wang , H , Lin , R , Porvari , K , Junttila , J , Huikuri , H , Immonen , K , Lakkisto , P , Magga , J , Tikkanen , I & Kerkelä , R 2020 , ' Vezf1 regulates cardiac structure and contractile function ' , EBioMedicine , vol. 51 , 102608 . https://doi.org/10.1016/j.ebiom.2019.102608; RIS: urn:052D9A511242228800BC9369B5E051AC; ORCID: /0000-0001-9935-6573/work/70948559; ORCID: /0000-0001-5700-6786/work/70950065; http://hdl.handle.net/10138/313484; 3d33700f-5f0a-4c5c-bb0f-435473201a5b; 000512904900044

الاتاحة: http://hdl.handle.net/10138/313484

المؤلفون: Narumanchi, Suneeta, Kalervo, Karri, Perttunen, Sanni, Wang, Hong, Immonen, Katariina, Kosonen, Riikka, Laine, Mika, Ruskoaho, Heikki, Tikkanen, Ilkka, Lakkisto, Päivi, Paavola, Jere

المساهمون: Medicum, HUS Heart and Lung Center, Kardiologian yksikkö, University of Helsinki, Regenerative pharmacology group, Drug Research Program, Division of Pharmacology and Pharmacotherapy, Department of Medicine, HUS Abdominal Center, University Management, Nefrologian yksikkö, Neurologian yksikkö, Department of Neurosciences, HUS Neurocenter

مصطلحات موضوعية: let-7c, miRNAs, epicardial cells, cardiac regeneration, proliferating cardiomyocytes, fibrin, HEART REGENERATION, CARDIOVASCULAR-DISEASE, MICRORNA THERAPEUTICS, DIFFERENTIATION, ENDOCARDIUM, EPICARDIUM, CAPACITY, FAMILY, SEPT7B, CELLS, General medicine, internal medicine and other clinical medicine, Biomedicine

وصف الملف: application/pdf

Relation: This work was supported by research funding of the Helsinki-Uusimaa Hospital District (state funding for university-level health research) (I.T.), and by grants from the Finnish Foundation for Laboratory Medicine (P.L.), the Finska Lakaresallskapet (I.T.), the Liv och Halsa Foundation (I.T. and P.L.), the Aarne Koskelo Foundation (S.N., I.T. and J.P.), the Finnish Cultural Foundation (S.N., H.W. and P.L.), the Orion Research Foundation (S.N.), the Finnish Foundation for Cardiovascular Research (S.N., H.R., I.T. and J.P.), the Sigrid Juselius Foundation (H.R.) and the Ida Montin Foundation (S.N.).; Narumanchi , S , Kalervo , K , Perttunen , S , Wang , H , Immonen , K , Kosonen , R , Laine , M , Ruskoaho , H , Tikkanen , I , Lakkisto , P & Paavola , J 2019 , ' Inhibition of let-7c Regulates Cardiac Regeneration after Cryoinjury in Adult Zebrafish ' , Journal of Cardiovascular Development and Disease , vol. 6 , no. 2 , 16 . https://doi.org/10.3390/jcdd6020016; ORCID: /0000-0001-5700-6786/work/61349559; ORCID: /0000-0001-9935-6573/work/61593291; ORCID: /0000-0001-8971-1359/work/61593744; http://hdl.handle.net/10138/305259; 206b7cd4-d6f5-45c6-9723-b2d57af0f78a; 000474248600003

الاتاحة: http://hdl.handle.net/10138/305259

المؤلفون: Chaurasiya, Vaishali, Pham, Dan Duc, Harju, Jukka, Juuti, Anne, Penttilä, Anne, Emmagouni, Sharath Kumar Goud, Nguyen, Van Dien, Zhang, Birong, Perttunen, Sanni, Keskitalo, Salla, Zhou, You, Pietiläinen, Kirsi H., Haridas, P.A. Nidhina, Olkkonen, Vesa M.

وصف الملف: application/pdf

Relation: https://orca.cardiff.ac.uk/id/eprint/164599/3/Human%20visceral%20adipose%20tissue%20microvascular%20endothelial%20cell%20isolation%20and%20establishment%20of%20co.pdf; Chaurasiya, Vaishali, Pham, Dan Duc, Harju, Jukka, Juuti, Anne, Penttilä, Anne, Emmagouni, Sharath Kumar Goud, Nguyen, Van Dien https://orca.cardiff.ac.uk/view/cardiffauthors/A2455488C.html, Zhang, Birong https://orca.cardiff.ac.uk/view/cardiffauthors/A2533698O.html, Perttunen, Sanni, Keskitalo, Salla, Zhou, You https://orca.cardiff.ac.uk/view/cardiffauthors/A2234625C.html orcid:0000-0002-1743-1291 orcid:0000-0002-1743-1291, Pietiläinen, Kirsi H., Haridas, P.A. Nidhina and Olkkonen, Vesa M. 2023. Human visceral adipose tissue microvascular endothelial cell isolation and establishment of co-culture with white adipocytes to analyze cell-cell communication. Experimental Cell Research 433 (2) , 113819. 10.1016/j.yexcr.2023.113819 https://doi.org/10.1016/j.yexcr.2023.113819 file https://orca.cardiff.ac.uk/id/eprint/164599/3/Human%20visceral%20adipose%20tissue%20microvascular%20endothelial%20cell%20isolation%20and%20establishment%20of%20co.pdf

الاتاحة: https://orca.cardiff.ac.uk/id/eprint/164599/
https://doi.org/10.1016/j.yexcr.2023.113819
https://orca.cardiff.ac.uk/id/eprint/164599/3/Human%20visceral%20adipose%20tissue%20microvascular%20endothelial%20cell%20isolation%20and%20establishment%20of%20co.pdf

المؤلفون: Wang, Hong, Segersvärd, Heli, Siren, Juuso, Perttunen, Sanni, Immonen, Katariina, Kosonen, Riikka, Chen, Yu-Chia, Tolva, Johanna, Laivuori, Mirjami, Mäyränpää, Mikko I., Kovanen, Petri T., Sinisalo, Juha, Laine, Mika, Tikkanen, Ilkka, Lakkisto, Päivi

وصف الملف: application/pdf

Relation: Wang, H.; Segersvärd, H.; Siren, J.; Perttunen, S.; Immonen, K.; Kosonen, R.; Chen, Y.-C.; Tolva, J.; Laivuori, M.; Mäyränpää, M.I.; Kovanen, P.T.; Sinisalo, J.; Laine, M.; Tikkanen, I.; Lakkisto, P. Tankyrase Inhibition Attenuates Cardiac Dilatation and Dysfunction in Ischemic Heart Failure. Int. J. Mol. Sci. 2022, 23, 10059.; http://hdl.handle.net/10138/349451

الاتاحة: http://hdl.handle.net/10138/349451

المؤلفون: Narumanchi, Suneeta, Kalervo, Karri, Perttunen, Sanni, Wang, Hong, Immonen, Katariina, Kosonen, Riikka, Laine, Mika, Ruskoaho, Heikki, Tikkanen, Ilkka, Lakkisto, Päivi, Paavola, Jere

وصف الملف: application/pdf

Relation: Narumanchi, S.; Kalervo, K.; Perttunen, S.; Wang, H.; Immonen, K.; Kosonen, R.; Laine, M.; Ruskoaho, H.; Tikkanen, I.; Lakkisto, P.; Paavola, J. Inhibition of let-7c Regulates Cardiac Regeneration after Cryoinjury in Adult Zebrafish. J. Cardiovasc. Dev. Dis. 2019, 6, 16.; http://hdl.handle.net/10138/348500

الاتاحة: http://hdl.handle.net/10138/348500

المؤلفون: Dash, Surjya Narayan, Narumanchi, Suneeta, Paavola, Jere, Perttunen, Sanni, Hong Wang, Lakkisto, Päivi, Tikkanen, Ilkka, Lehtonen, Sanna

المصدر: American Journal of Physiology: Heart & Circulatory Physiology; May2017, Vol. 312 Issue 5, pH1085-H1095, 11p

مصطلحات موضوعية: HEART cells, MYOFIBRILS, HEART failure

المؤلفون: Haukijärvi, Noora, Perttunen, Sanni

المساهمون: Turun ammattikorkeakoulu

مصطلحات موضوعية: lähiluonto, ympäristökasvatus, kestävä kehitys, ympäristöherkkyys, oppimateriaali, oppimisympäristö, fi=Luonnonvara- ja ympäristöala|sv=Bioekonomi och Miljöbranschen|en=Natural Resources and Environment, Kestävän kehityksen koulutusohjelma, hist, phil

Relation: http://www.theseus.fi/handle/10024/69011

الاتاحة: http://www.theseus.fi/handle/10024/69011