المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L Harris, Karl J Morten, Francesca M Buffa

المصدر: PLoS Computational Biology, Vol 20, Iss 3, p e1011944 (2024)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011944&type=printable; https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

URL الوصول: https://doaj.org/article/0eb01951447743aaa95598c797984cf8

المؤلفون: Shaliny Ramachandran, Tiffany S. Ma, Jon Griffin, Natalie Ng, Iosifina P. Foskolou, Ming-Shih Hwang, Pedro Victori, Wei-Chen Cheng, Francesca M. Buffa, Katarzyna B. Leszczynska, Sherif F. El-Khamisy, Natalia Gromak, Ester M. Hammond

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/53d171bea0d243d0a270df932d095042

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/S4_Fig_-/25420548

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s008

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Multi-scale_modelling_framework_/25420539

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s005

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/sigQC_metrics_were_calculated_for_our_network_genes_in_TCGA_and_CCLE_breast_cancer_RNA_Seq_datasets_/25420554

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s010

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Methodology_and_Parameters_/25420527

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s001

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/The_cell_regulatory_network_of_our_model_microC_model_/25420542

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s006

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Different_time_scales_are_used_for_different_processes_/25420545

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s007

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Dynamics_of_total_glycolytic_glycoATP_and_OXPHOS_mitoATP_cell_populations_over_time_under_different_application_strategies_of_MCT1_and_GLUT1_inhibitors_/25420578

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s018

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Metabolic_symbiotic_simulations_with_network_gene_alterations_Enriched_and_Knockout_-_status_and_wild_type_WT_status_/25420557

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s011

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Symbiosis-induced_changes_of_glucose_and_oxygen_of_the_microenvironment_over_time_/25420560

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s012

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Tumour_growth_curves_are_shown_for_different_combinations_of_oxygen_and_glucose_/25420566

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s014

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Tumour_growth_over_time_at_different_combinations_of_GLUT1_and_MCT1_inhibitors_/25420572

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s016

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Tumour_growth_under_different_environmental_conditions_different_levels_of_glucose_lactate_and_oxygen_are_shown_for_p53wt_and_p53-_cells_/25420563

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s013

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/The_effect_of_half-saturation_coefficients_of_oxygen_and_glucose_on_the_metabolic_pathways_is_shown_/25420569

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s015

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/MCT1_and_GLUT1_inhibition_/25420575

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s017

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Partial_correlation_coefficients_between_symbiosis-induced_growth_increment_of_tumour_and_model_parameters_over_time_/25420584

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s020

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/journal_contribution/Partial_correlation_coefficients_between_model_parameters_and_outputs_over_time_/25420581

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s019

المؤلفون: Evangelos Chatzaroulas, Vytenis Sliogeris, Pedro Victori, Francesca M. Buffa, Sotiris Moschoyiannis, Roman Bauer

المصدر: Symmetry; Volume 14; Issue 5; Pages: 1009

مصطلحات موضوعية: cancer, hallmarks, complex networks, network analysis

وصف الملف: application/pdf

Relation: Biology and Symmetry/Asymmetry; https://dx.doi.org/10.3390/sym14051009

الاتاحة: https://doi.org/10.3390/sym14051009

المؤلفون: Pahala Gedara Jayathilake, Pedro Victori, Clara E. Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L. Harris, Karl J. Morten, Francesca M. Buffa

مصطلحات موضوعية: Biochemistry, Genetics, Physiology, Evolutionary Biology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, tumour cells tend, symbiotic dynamics depends, reduce tumour growth, lower energy efficiency, exogenous lactate produced, study metabolic cooperation, oxygenated cells exposed, mitochondrial respiration makes, hypoxic tumour cells, using aerobic glycolysis, mitochondrial respiration, cooperation reduces, aerobic glycolysis, warburg effect, stoichiometric equations, specific cell, scale approach, results suggest, results show, overall advantage, metabolic symbiosis, inhibitor concentrations, environmental glucose

Relation: https://figshare.com/articles/figure/Cell_Regulatory_Network_/25420536

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011944.s004