المؤلفون: Ana Cristina Lima Leite, Paulo André Teixeira de Moraes Gomes, Luiz Alberto Barros Freitas, Luciana Rabelo Pessoa Siqueira, Juliana Maria da Conceição, Ignes Regina dos Santos, Aline Ferreira Pinto, Vanessa Gouveia de Melo Silva, Janine Siqueira Nunes, Marcos Veríssimo de Oliveira Cardoso, Lindomar José Pena

المصدر: Current Topics in Medicinal Chemistry. 23:426-439

مصطلحات موضوعية: Drug Discovery, General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d7d0c9ea7524dee0bfdd6bd88dc0992
https://doi.org/10.2174/1568026623666221222124433

المؤلفون: Luiz Felipe Gomes Rebello Ferreira, Muhammad Haroon, Muhammad Nawaz Tahir, Tashfeen Akhtar, Valéria Rêgo Alves Pereira, Fabiano Amaro de Sousa, Rafaela Salgado Ferreira, Rafael E. O. Rocha, Mabilly Cox Holanda de Barros Dias, Ana Cristina Lima Leite, Marcelo Zaldini Hernandes, Shahid Hameed, Paulo André Teixeira de Moraes Gomes, Aline C Santos

المصدر: ChemistrySelect. 4:13163-13172

مصطلحات موضوعية: Acetic acid, chemistry.chemical_compound, chemistry, biology, Design synthesis, Biochemistry, General Chemistry, Trypanosoma cruzi, biology.organism_classification, Leishmania, In vitro

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::adba5fa2bdbb276346208798cdd24491
https://doi.org/10.1002/slct.201902561

المؤلفون: Larissa Pelágia de Lima Ferreira, Lucianna Rabelo Pessoa de Siqueira, Moacyr Jesus Barreto de Melo Rêgo, Ana Cristina Lima Leite, Paulo André Teixeira de Moraes Gomes

المصدر: European Journal of Medicinal Chemistry. 170:237-260

مصطلحات موضوعية: Thiosemicarbazones, Cancer therapy, Antineoplastic Agents, Cell Cycle Proteins, Context (language use), Computational biology, 01 natural sciences, Metastasis, 03 medical and health sciences, chemistry.chemical_compound, Drug Delivery Systems, Multi target, Neoplasms, Drug Discovery, medicine, Animals, Humans, Thiazole, 030304 developmental biology, Pharmacology, 0303 health sciences, 010405 organic chemistry, Drug discovery, Organic Chemistry, Intracellular Signaling Peptides and Proteins, Cancer, General Medicine, medicine.disease, 0104 chemical sciences, Thiazoles, chemistry, Tumor progression, Disease Progression, Thiazolidines

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21f18bc21ab321175e29af8a80cf60b
https://doi.org/10.1016/j.ejmech.2019.03.024

المؤلفون: Aldilane Gonçalves da Fonseca, Allanny Alves Furtado, Matheus De Freitas Fernandes Pedrosa, Elaine C. Gavioli, Ana Cristina Lima Leite, Luzia Leiros De Sena Fernandes Ribeiro Dantas, Maira Galdino da Rocha Pitta, Moacyr Jesus Barreto de Melo Rêgo, Joquebede Pereira Rodrigues, Telma Maria Araújo Moura Lemos, Paulo André Teixeira de Moraes Gomes, Marco Polo Da Costa Alencar Filho, Vanessa Gouveia de Melo Silva

المصدر: Biomedical Reports

مصطلحات موضوعية: Leukocyte migration, paw edema, medicine.drug_class, acetic acid-induced writhing reflex, Central nervous system, Inflammation, Pharmacology, General Biochemistry, Genetics and Molecular Biology, Anti-inflammatory, chemistry.chemical_compound, zymosan-induced air-pouch model, formalin test, medicine, General Pharmacology, Toxicology and Pharmaceutics, mouse, isatin-thiosemicarbazone, General Neuroscience, Articles, General Medicine, Motor coordination, Carrageenan, medicine.anatomical_structure, Nociception, chemistry, Apoptosis, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24a165de192ff0a73bbf2d68e2894685
https://doi.org/10.3892/br.2021.1437

المؤلفون: Rafael Oliveira, Luiz Carlos Alves, Vanessa Gouveia de Melo Silva, Valéria Rêgo Alves Pereira, Fábio André Brayner, Denise Duarte, Marcos Veríssimo de Oliveira Cardoso, Ignes Regina Dos Santos, Raquel Pereira, Ana Cristina Lima Leite, Fabiano Amaro de Sousa, Paulo André Teixeira de Moraes Gomes, Aline Caroline da Silva Santos, Juliana Maria da Conceição, Fátima Nogueira

المصدر: ChemMedChem. 15(22)

مصطلحات موضوعية: Chagas disease, Antiparasitic, medicine.drug_class, Trypanosoma cruzi, Plasmodium falciparum, Phthalimides, 01 natural sciences, Biochemistry, Microbiology, Structure-Activity Relationship, Parasitic Sensitivity Tests, parasitic diseases, Drug Discovery, medicine, Cytotoxic T cell, General Pharmacology, Toxicology and Pharmaceutics, Cytotoxicity, Pharmacology, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, Biological activity, biology.organism_classification, medicine.disease, Trypanocidal Agents, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Benznidazole, Molecular Medicine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530cffd36f72f66914dd95bc6c4970f2
https://pubmed.ncbi.nlm.nih.gov/32813331

المؤلفون: Sheilla Andrade de Oliveira, Edna de Farias Santiago, Ana Cristina Lima Leite, Paulo André Teixeira de Moraes Gomes, Carlos André Laranjeira Miranda Filho, Fábio André Brayner, Fabiano Amaro de Sousa, Juliana Maria da Conceição, Luiz Carlos Alves, Gevanio Bezerra de Oliveira Filho, Miria de Oliveira Barbosa, Arsênio Rodrigues Oliveira

المصدر: Parasitology Research. 117:2105-2115

مصطلحات موضوعية: 0301 basic medicine, 030106 microbiology, Antiprotozoal Agents, Phthalimides, Schistosomiasis, In Vitro Techniques, Biology, Microbiology, 03 medical and health sciences, parasitic diseases, medicine, Animals, Schistosoma, General Veterinary, Schistosoma mansoni, General Medicine, Viral tegument, medicine.disease, biology.organism_classification, Schistosomiasis mansoni, In vitro, Praziquantel, Thiazoles, 030104 developmental biology, Infectious Diseases, Insect Science, Toxicity, Microscopy, Electron, Scanning, Ultrastructure, Parasitology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d30871bff8bd1fc60a16218c7759fd
https://doi.org/10.1007/s00436-018-5897-4

المؤلفون: Miria de Oliveira Barbosa, Teresinha Gonçalves da Silva, Ana Cristina Lima Leite, Temístocles Italo de Santana, Paulo André Teixeira de Moraes Gomes, Anne Cecília Nascimento da Cruz

المصدر: European Journal of Medicinal Chemistry. 144:874-886

مصطلحات موضوعية: 0301 basic medicine, Antiparasitic, medicine.drug_class, Antineoplastic Agents, Hemolysis, 01 natural sciences, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, Tumor Cells, Cultured, medicine, Humans, Structure–activity relationship, Thiazole, Cell Proliferation, Pharmacology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Cell growth, Organic Chemistry, General Medicine, Cell cycle, Antimicrobial, 0104 chemical sciences, Thiazoles, 030104 developmental biology, Biochemistry, chemistry, Mechanism of action, DNA fragmentation, Drug Screening Assays, Antitumor, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acc9fda434c7f5c642b028eb447714fb
https://doi.org/10.1016/j.ejmech.2017.12.040

المؤلفون: Valéria Rêgo Alves Pereira, Aline Caroline da Silva Santos, Gedália de Cássia Silva, Luiz Carlos Alves, Fábio André Brayner, Carlos A. de Simone, Paulo André Teixeira de Moraes Gomes, Luiz Alberto Barros Freitas, Elis Dionísio da Silva, Franciely Nayara do Nascimento Albuquerque, Ana Cristina Lima Leite

المصدر: Chemico-Biological Interactions. 345:109561

مصطلحات موضوعية: Isatin, 0301 basic medicine, Stereochemistry, Antiparasitic, medicine.drug_class, Toxicology, Inhibitory Concentration 50, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, Thiazole, Trypanosoma cruzi, Leishmania, Miltefosine, biology, Biological activity, General Medicine, biology.organism_classification, Trypanocidal Agents, Thiazoles, 030104 developmental biology, chemistry, Benznidazole, Drug Design, 030220 oncology & carcinogenesis, Leishmania infantum, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c515fabc6b8e03c89437f1f40ae9123
https://doi.org/10.1016/j.cbi.2021.109561

المؤلفون: Marcos Veríssimo de Oliveira Cardoso, Ana Cristina Lima Leite, Diogo Rodrigo Magalhães Moreira, Thiago André Ramos dos Santos, Aline Caroline da Silva, Paulo André Teixeira de Moraes Gomes, Elany Barbosa da Silva, José Wanderlan Pontes Espíndola, Valéria Rêgo Alves Pereira

المصدر: Biomedicine & Pharmacotherapy. 82:555-560

مصطلحات موضوعية: Thiosemicarbazones, 0301 basic medicine, Antineoplastic Agents, Apoptosis, Biology, Pharmacology, Jurkat cells, Jurkat Cells, Mice, 03 medical and health sciences, 0302 clinical medicine, Immune system, medicine, Animals, Humans, Immunologic Factors, Cytotoxicity, Tumor Necrosis Factor-alpha, Macrophages, Cancer, Biological activity, General Medicine, medicine.disease, Interleukin-10, Thiazoles, Interleukin 10, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer cell, Tumor necrosis factor alpha, HT29 Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5de2672975db45e3fb26885b88ef1ae1
https://doi.org/10.1016/j.biopha.2016.05.038

المؤلفون: Paulo André Teixeira de Moraes Gomes, Marcos Veríssimo de Oliveira Cardoso, Gevanio Bezerra de Oliveira Filho, Floriano Paes Silva Junior, Regina Celia Bressan Queiroz de Figueiredo, José Wanderlan Pontes Espíndola, Lívia Bandeira Costa, Thays Gabrielle de Jesus Silva, Ana Cristina Lima Leite, Julio Martin, Pedro Henrique Monteiro Torres

المصدر: Bioorganic & Medicinal Chemistry. 24:1608-1618

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Chagas disease, Quantitative structure–activity relationship, Cell Survival, Stereochemistry, Trypanosoma cruzi, Clinical Biochemistry, Quantitative Structure-Activity Relationship, Pharmaceutical Science, Hydrazone, Drug resistance, 01 natural sciences, Biochemistry, Chemical library, Mice, 03 medical and health sciences, chemistry.chemical_compound, Parasitic Sensitivity Tests, parasitic diseases, Drug Discovery, medicine, Animals, Humans, Molecular Biology, Trypanocidal agent, chemistry.chemical_classification, Molecular Structure, biology, 010405 organic chemistry, Organic Chemistry, Hydrazones, Biological activity, Hep G2 Cells, biology.organism_classification, medicine.disease, Trypanocidal Agents, 0104 chemical sciences, 030104 developmental biology, chemistry, NIH 3T3 Cells, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea095fda054f2b058b4ccd53082d7b86
https://doi.org/10.1016/j.bmc.2016.02.027

المؤلفون: Valéria Rêgo Alves Pereira, Marcos Veríssimo de Oliveira Cardoso, Andresa Pereira de Oliveira Mendes, Lucianna Rabelo Pessoa de Siqueira, Maria Carolina Accioly Brelaz de Castro, Ana Cristina Lima Leite, Paulo André Teixeira de Moraes Gomes, Milena Botelho Pereira Soares, Tanira Matutino Bastos, Edna de Farias Santiago, Arsênio Rodrigues Oliveira, Fábio André Brayner, Miria de Oliveira Barbosa, Diogo Rodrigo Magalhães Moreira

المصدر: European Journal of Medicinal Chemistry. 111:46-57

مصطلحات موضوعية: 0301 basic medicine, Chagas disease, Trypanosoma cruzi, Phthalimides, Spleen, Mitochondrion, 01 natural sciences, Microbiology, Mice, 03 medical and health sciences, Parasitic Sensitivity Tests, Chlorocebus aethiops, parasitic diseases, Drug Discovery, medicine, Animals, Cytotoxicity, Vero Cells, Cell Proliferation, Pharmacology, Mice, Inbred BALB C, biology, 010405 organic chemistry, Cell growth, Endoplasmic reticulum, Organic Chemistry, General Medicine, biology.organism_classification, medicine.disease, Trypanocidal Agents, 0104 chemical sciences, Thiazoles, 030104 developmental biology, medicine.anatomical_structure, Benznidazole, Immunology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08172faeb721db764e3dbf6dcf4f1db8
https://doi.org/10.1016/j.ejmech.2016.01.010

المؤلفون: Ana Cristina Lima Leite, Paulo André Teixeira de Moraes Gomes, Lindomar Pena

المصدر: Mini reviews in medicinal chemistry. 19(1)

مصطلحات موضوعية: 0301 basic medicine, Isatin, viruses, Alphavirus, Dengue virus, Arbovirus Infections, medicine.disease_cause, Antiviral Agents, Virus, Zika virus, 03 medical and health sciences, Drug Discovery, medicine, Animals, Humans, Chikungunya, Pharmacology, biology, virus diseases, General Medicine, biochemical phenomena, metabolism, and nutrition, Japanese encephalitis, medicine.disease, biology.organism_classification, Virology, Flavivirus, 030104 developmental biology, Encephalitis, Arboviruses

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3017e82b216ee21d08f06e20dab5652e
https://pubmed.ncbi.nlm.nih.gov/29692243

المؤلفون: Suellen Melo Tibúrcio Cavalcanti, Elizabeth Fernanda de Oliveira Borba, Marcos Veríssimo de Oliveira Cardoso, Teresinha Gonçalves da Silva, Arsênio Rodrigues Oliveira, Gevanio Bezerra de Oliveira Filho, Ana Cristina Lima Leite, Paulo André Teixeira de Moraes Gomes, Lawrence J. Abraham, Belinda J. Kaskow, Lucas Cunha Duarte Coelho, Diogo Rodrigo Magalhães Moreira, Lucianna Rabelo Pessoa de Siqueira, Mahdad Karimi, Miria de Oliveira Barbosa

المصدر: Med. Chem. Commun.. 5:758-765

مصطلحات موضوعية: Pharmacology, Programmed cell death, Organic Chemistry, Pharmaceutical Science, Biology, Biochemistry, Jurkat cells, Cell biology, Phthalimide, chemistry.chemical_compound, Immune system, chemistry, Apoptosis, Drug Discovery, Molecular Medicine, Secretion, Tumor necrosis factor alpha, Cytotoxicity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8e6bb330897304ba8b791082bd3b3123
https://doi.org/10.1039/c4md00070f

المؤلفون: Natáli Tereza Capistrano Costa, Rafaela Salgado Ferreira, Thiago André Ramos dos Santos, Edna de Farias Santiago, Marcos Veríssimo de Oliveira Cardoso, Ana Cristina Lima Leite, Marcelo Zaldini Hernandes, Glaécia Aparecida do Nascimento Pereira, Valéria Rêgo Alves Pereira, Aline Caroline da Silva, Diogo Rodrigo Magalhães Moreira, Fábio André Brayner dos Santosd, Paulo André Teixeira de Moraes Gomes, Miria de Oliveira Barbosa

المصدر: European journal of medicinal chemistry. 121

مصطلحات موضوعية: 0301 basic medicine, Chagas disease, Stereochemistry, Antiparasitic, medicine.drug_class, Protein Conformation, medicine.medical_treatment, Trypanosoma cruzi, Protozoan Proteins, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, Mice, parasitic diseases, Drug Discovery, Chlorocebus aethiops, medicine, Animals, Thiazole, Semicarbazone, Vero Cells, Pharmacology, Protease, biology, 010405 organic chemistry, Organic Chemistry, General Medicine, biology.organism_classification, medicine.disease, Trypanocidal Agents, 0104 chemical sciences, Molecular Docking Simulation, Cysteine Endopeptidases, Thiazoles, 030104 developmental biology, Biochemistry, chemistry, Benznidazole, Drug Design, Ultrastructure, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd8d6dce84a7e5471a281d7d7dcb64f
https://pubmed.ncbi.nlm.nih.gov/27295485

المؤلفون: Ana Cristina Lima Leite, Luiz Carlos Alves, Thiago André Ramos dos Santos, Sheilla Andrade de Oliveira, Gevânio Bezerra de Oliveira Filho, Edna de Farias Santiago, Gabriel Gazzoni Araújo Gonçalves, Anekécia Lauro Da Silva, Fábio André Brayner, Andréia Ferreira de Barros, Paulo André Teixeira de Moraes Gomes, Diogo Rodrigo Magalhães Moreira, Aline Caroline da Silva, Valéria Rêgo Alves Pereira, Almir Gonçalves Wanderley

المصدر: Antimicrobial agents and chemotherapy. 58(1)

مصطلحات موضوعية: Drug, Thiosemicarbazones, media_common.quotation_subject, Schistosomicides, Schistosomiasis, Pharmacology, chemistry.chemical_compound, parasitic diseases, medicine, Animals, Humans, Pharmacology (medical), Experimental Therapeutics, Thiazole, Schistosoma, media_common, biology, Viral tegument, Schistosoma mansoni, biology.organism_classification, medicine.disease, Praziquantel, Thiazoles, Infectious Diseases, chemistry, Immunology, Microscopy, Electron, Scanning, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b829ae9c5c74ff07843841f4b1dc933a
https://pubmed.ncbi.nlm.nih.gov/24165185

المؤلفون: Marcos Veríssimo de Oliveira Cardoso, Rajendra M. Srivastava, Ana Cristina Lima Leite, Diogo Rodrigo de Magalhães Moreira, Elany Barbosa da Silva, Paulo André Teixeira de Moraes Gomes, Gevanio Bezerra de Oliveira Filho

المصدر: Proceedings of the 14th Brazilian Meeting on Organic Synthesis Proceedings.

مصطلحات موضوعية: chemistry.chemical_classification, Metal, chemistry.chemical_compound, Materials science, chemistry, visual_art, Aromatic ketones, visual_art.visual_art_medium, Hydrazone, Thiazole, Ultrasound irradiation, Nuclear chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::80c45b2d26de669eccaecfca4dea0d14
https://doi.org/10.5151/chempro-14bmos-r0214-1

المؤلفون: Gevanio Bezerra de Oliveira Filho, Diogo Rodrigo de Magalhães Moreira, Luca Cunha D. Coêlho, Marcos Veríssimo de Oliveira Cardoso, Lawrence J. Abraham, Ana Cristina Lima Leite, Elany Barbosa da Silva, Suellen Melo Tibúrcio Cavalcanti, Paulo André Teixeira de Moraes Gomes

المصدر: Proceedings of the 14th Brazilian Meeting on Organic Synthesis Proceedings.

مصطلحات موضوعية: Phthalimide, Thalidomide, chemistry.chemical_compound, chemistry, Cell culture, Apoptosis, Ic50 values, medicine, Tumor necrosis factor alpha, Pharmacology, Jurkat cells, Chemical library, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::677137f1694d6f1f144a0a923f5ecad3
https://doi.org/10.5151/chempro-14bmos-r0214-2