المؤلفون: Paul D Wes, Amy Easton, John Corradi, Donna M Barten, Nino Devidze, Lynn B DeCarr, Amy Truong, Aiqing He, Nestor X Barrezueta, Craig Polson, Clotilde Bourin, Marianne E Flynn, Stefanie Keenan, Regina Lidge, Jere Meredith, Joanne Natale, Sethu Sankaranarayanan, Greg W Cadelina, Charlie F Albright, Angela M Cacace

المصدر: PLoS ONE, Vol 9, Iss 8, p e106050 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4143352?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/9d297f74a7fd482c94e62f7c38c08e4e

المؤلفون: Veronica Jové, Heather Wheeler, Chiachin Wilson Lee, David R. Healy, Kymberly Levine, Erik C. Ralph, Masaya Yamaguchi, Ziyue Karen Jiang, Edward Cabral, Yingrong Xu, Jeffrey Stock, Bing Yang, Anand Giddabasappa, Paula Loria, Agustin Casimiro-Garcia, Benedikt M. Kessler, Adán Pinto-Fernández, Véronique Frattini, Paul D. Wes, Feng Wang

المصدر: iScience, Vol 27, Iss 4, Pp 109593- (2024)

مصطلحات موضوعية: Immunity, Immune response, Cell biology, Cancer, Science

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004224008150; https://doaj.org/toc/2589-0042

URL الوصول: https://doaj.org/article/9891ba2dcc8a4ca097d1e8e73e654873

المؤلفون: Veronica Jové, Heather Wheeler, Chiachin Wilson Lee, David R. Healy, Kymberly Levine, Erik C. Ralph, Bing Yang, Anand Giddabasappa, Paula Loria, Masaya Yamaguchi, Agustin Casimiro-Garcia, Benedikt M. Kessler, Adán Pinto-Fernández, Véronique Frattini, Paul D. Wes, Feng Wang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e620b6a1b8a7c1fb20f83ca5907eeee9
https://doi.org/10.1101/2023.03.23.533924

المؤلفون: Vallen Graham W, Deguzman J, Kim Marquette, Caroline Graff, Riyez Karim, Petro M, Thomas P. Sakmar, Rita Agostinelli, Kerry Kelleher, Lioudmila Tchistiakova, Alessandra Bonito-Oliva, Anna-Karin Lindström, Paul D. Wes, Wood Km

مصطلحات موضوعية: Amyloid, biology, Amyloid beta, Chemistry, medicine.drug_class, Binding protein, Monoclonal antibody, Molecular biology, Pathogenesis, Fibril formation, Chaperone (protein), biology.protein, medicine, Immunohistochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b14dd81363a25c2bfaae8ff3a9016ed

المؤلفون: Paul D. Wes, Dario Doller

المصدر: Good Research Practice in Non-Clinical Pharmacology and Biomedicine ISBN: 9783030336554

مصطلحات موضوعية: 0301 basic medicine, Modalities, Drug discovery, Interface (Java), media_common.quotation_subject, Identity (social science), Context (language use), Chemist, Data science, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Quality (business), 030217 neurology & neurosurgery, media_common, Diversity (politics)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::04460e0fd9df4abaedbbbef740779dfb
https://doi.org/10.1007/164_2019_281

المؤلفون: Paul D. Wes, Bart J. L. Eggen, Inge R. Holtman, Erik Boddeke, Thomas Möller

المساهمون: Molecular Neuroscience and Ageing Research (MOLAR), Translational Immunology Groningen (TRIGR), Restoring Organ Function by Means of Regenerative Medicine (REGENERATE)

المصدر: Glia, 64(2), 197-213. Wiley

مصطلحات موضوعية: 0301 basic medicine, Cell type, Cell, Genomics, Biology, Epigenesis, Genetic, Transcriptome, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, medicine, Aging brain, Animals, Humans, Microglia, Gene Expression Profiling, Macrophages, Neurodegenerative Diseases, Gene expression profiling, 030104 developmental biology, medicine.anatomical_structure, Neurology, biology.protein, Neuroscience, 030217 neurology & neurosurgery, Neurotrophin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc716c3c2fe891bd4c665770a38f421
https://doi.org/10.1002/glia.22866

المؤلفون: Ilia D. Vainchtein, Nieske Brouwer, Inge R. Holtman, Paula R. Sola, Mariana Matera Veras, Paul D. Wes, Suely Kazue Nagahashi Marie, Thais F. Galatro, Erik Boddeke, Antonio M. Lerario, Sueli Mieko Oba-Shinjo, Jon D. Laman, Bart J. L. Eggen, Tulio Felipe Pereira, Thomas Möller, Mari Cleide Sogayar, Wilfred F. A. den Dunnen, Renata Elaine Paraizo Leite, Carlos Augusto Pasqualucci

المساهمون: Molecular Neuroscience and Ageing Research (MOLAR), Translational Immunology Groningen (TRIGR), Restoring Organ Function by Means of Regenerative Medicine (REGENERATE)

المصدر: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nature neuroscience, 20(8), 1162-1171. NATURE AMERICA INC

مصطلحات موضوعية: 0301 basic medicine, Aging, Gene Expression, Biology, ASTROCYTES, DISEASE, 03 medical and health sciences, 0302 clinical medicine, GENE-EXPRESSION SIGNATURE, Cell surface receptor, CX3CR1, medicine, Humans, Receptor, CD11b Antigen, Microglia, RECEPTOR, General Neuroscience, Gene Expression Profiling, Neurodegeneration, Cell Cycle, PROLIFERATION, EXPRESSÃO GÊNICA, Brain, Human brain, medicine.disease, HUMAN BRAIN, Axons, Cell biology, 030104 developmental biology, Neuroimmunology, medicine.anatomical_structure, Integrin alpha M, CELLS, biology.protein, ADULT-MOUSE, CNS, REGULATOR, Neuroscience, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ce92501624910dd563fa2aab75a1a9
https://pubmed.ncbi.nlm.nih.gov/28671693

المؤلفون: Hendrikus Boddeke, Zoë A. Hughes, Paul D. Wes, Roland G. W. Staal, Elena Dale, Faten A. Sayed, Gwenn A. Garden, Brian M. Campbell, Frederique Bard, Damien D. Pearse, Claudia Eder, Li Gan, Thomas Möller, Knut Biber, Anindya Bhattacharya

المصدر: Glia. 64(10)

مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, Databases, Factual, medicine.drug_class, Antibiotics, REGULATED GENE-EXPRESSION, Minocycline, AMYOTROPHIC-LATERAL-SCLEROSIS, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, PRO-INFLAMMATORY MICROGLIA, medicine, SPINAL-CORD-INJURY, Animals, Humans, Amyotrophic lateral sclerosis, Spinal cord injury, TRANSGENIC MICE, Microglia, business.industry, Multiple sclerosis, INDUCED AUTOIMMUNE HEPATITIS, MULTIPLE-SCLEROSIS, MOUSE MODEL, medicine.disease, Anti-Bacterial Agents, inhibitor, CYTOKINE SECRETION, 030104 developmental biology, medicine.anatomical_structure, nervous system, Neurology, Immunology, HUNTINGTONS-DISEASE, Cytokine secretion, lack of specificity, business, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a60f4f530ef10065ee3106690b5dcbc7
https://pubmed.ncbi.nlm.nih.gov/27246804

المؤلفون: Maria Ondrejcakova, Natasa Hlavacova, Marianne E. Flynn, Stanislav Babic, Daniela Jezova, Paul D. Wes, Patricia Poundstone, Harald Murck

المصدر: The International Journal of Neuropsychopharmacology. 15:247-265

مصطلحات موضوعية: Male, medicine.medical_specialty, Inflammation, Random Allocation, chemistry.chemical_compound, Internal medicine, Hyperaldosteronism, Gene expression, medicine, Animals, Pharmacology (medical), Rats, Wistar, Aldosterone, Pharmacology, Depressive Disorder, Major, Depression, medicine.disease, Pathophysiology, Rats, Gene expression profiling, Psychiatry and Mental health, Treatment Outcome, Endocrinology, Gene Expression Regulation, chemistry, Major depressive disorder, medicine.symptom, Psychology, Behavioural despair test

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ca3776e9cd00b1aa973bd41c087bb8
https://doi.org/10.1017/s1461145711000368

المؤلفون: Leo J. Pallanck, Paul D. Wes, Laurie A. Andrews, Katherine F. Moore, Paul J. Muchowski, Joyoti Dey, Kien Trinh

المصدر: The Journal of Neuroscience. 28:465-472

مصطلحات موضوعية: Parkinson's disease, Tyrosine 3-Monooxygenase, Nerve Tissue Proteins, Biology, medicine.disease_cause, Parkin, Animals, Genetically Modified, chemistry.chemical_compound, Isothiocyanates, medicine, Animals, Drosophila Proteins, Disulfides, Neurons, Cell Death, Dose-Response Relationship, Drug, General Neuroscience, Age Factors, Parkinson Disease, Articles, Glutathione, medicine.disease, Metabolic Detoxication, Phase II, nervous system diseases, Cell biology, Allyl Compounds, Disease Models, Animal, Glutathione S-transferase, nervous system, Biochemistry, chemistry, Sulfoxides, Mutation, Nerve Degeneration, Phase II Detoxification, Toxicity, alpha-Synuclein, biology.protein, Synuclein, Drosophila, Metabolic Networks and Pathways, Thiocyanates, Oxidative stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4a9d7957866f7e16a9def9ff9957634
https://doi.org/10.1523/jneurosci.4778-07.2008

المؤلفون: Li Gan, Paul D. Wes, Frederique Bard, Faten A. Sayed

المصدر: Glia. 64(10)

مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, Cell type, Amyloid, medicine.medical_treatment, tau Proteins, Disease, Receptors, Fc, Biology, Antibodies, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Alzheimer Disease, medicine, Animals, Humans, Amyloid beta-Peptides, Microglia, TREM2, Immunotherapy, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, nervous system, Neurology, Immunology, Alzheimer's disease, Neuroscience, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed1470e74b707247dd7531bef95e26a0
https://pubmed.ncbi.nlm.nih.gov/27100611

المؤلفون: Thomas Möller, Jeremy A. Miller, Wandert Schaafsma, Elly M. Hol, Zhuoran Yin, Paul D. Wes, Bart J. L. Eggen, Inge R. Holtman, Nieske Brouwer, Erik Boddeke, Willem Kamphuis, Marie Orre, Divya Raj

المساهمون: Molecular Neuroscience and Ageing Research (MOLAR), Translational Immunology Groningen (TRIGR), Restoring Organ Function by Means of Regenerative Medicine (REGENERATE), Netherlands Institute for Neuroscience (NIN), Cellular and Computational Neuroscience (SILS, FNWI)

المصدر: Acta Neuropathologica Communications
Acta neuropathologica communications, 3:31. BioMed Central Ltd.
Acta Neuropathologica Communications [E], 3. BioMed Central
Acta neuropathologica communications, 3. BioMed Central
Acta Neuropathologica Communications, 3. BioMed Central

مصطلحات موضوعية: Aging, Central nervous system, Biology, Research Support, Pathology and Forensic Medicine, Cellular and Molecular Neuroscience, Mice, Alzheimer Disease, Gene expression, medicine, Journal Article, Animals, Humans, Non-U.S. Gov't, Neuroinflammation, Inflammation, Microglia, Research Support, Non-U.S. Gov't, Research, Neurodegeneration, NF-kappa B, Neurodegenerative Diseases, medicine.disease, NFKB1, Phenotype, Up-Regulation, medicine.anatomical_structure, Neurology (clinical), Signal transduction, Transcriptome, Neuroscience, Meta-Analysis, Signal Transduction

وصف الملف: application/pdf; image/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ce257f4815d67cc3ceb0bf52f8638d
http://europepmc.org/articles/PMC4489356

المؤلفون: Nancy M. Bonini, Peter Heutink, Patrizia Rizzu, Alexander J. Whitworth, Paul D. Wes, Leo J. Pallanck, Cecilia E. Armstrong-Gold, Marc C. Meulener

المساهمون: Biological Psychology

المصدر: Meulener, M, Whitworth, A J, Armstrong-Gold, C E, Rizzu-Heutink, P, Heutink, P, Wes, P D, Pallanck, L J & Bonini, N M 2005, ' Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease ', Current Biology, vol. 15, no. 17, pp. 1572-1577 . https://doi.org/10.1016/j.cub.2005.07.064
Current Biology, 15(17), 1572-1577. Cell Press

مصطلحات موضوعية: Paraquat, Parkinson's disease, Mutant, Blotting, Western, Molecular Sequence Data, Protein Deglycase DJ-1, Nerve Tissue Proteins, Oxidative phosphorylation, Biology, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Germline, Animals, Genetically Modified, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Rotenone, medicine, Animals, Cluster Analysis, Drosophila Proteins, Amino Acid Sequence, Gene, Crosses, Genetic, Phylogeny, 030304 developmental biology, Genetics, Neurons, 0303 health sciences, Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Computational Biology, Parkinson Disease, medicine.disease, Survival Analysis, Oxidative Stress, chemistry, Mutation, Drosophila, General Agricultural and Biological Sciences, Sequence Alignment, 030217 neurology & neurosurgery, Oxidative stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::344cc3a22ef9c0f2ba0378a835ccbf37
https://doi.org/10.1016/j.cub.2005.07.064

المؤلفون: Paul D. Wes, Craig Montell, Douglas A. Harrison, Douglas A. Andres, Susan M.W. Harrison, Jennifer L. Rudolph, Michael L. Spencer

المصدر: Developmental Dynamics. 232:817-826

مصطلحات موضوعية: MAPK/ERK pathway, Embryo, Nonmammalian, Molecular Sequence Data, Son of Sevenless, GTPase, Eye, Animals, Genetically Modified, Calmodulin, hemic and lymphatic diseases, Animals, Drosophila Proteins, Wings, Animal, Ras subfamily, Small GTPase, Amino Acid Sequence, Transgenes, Cells, Cultured, Conserved Sequence, Monomeric GTP-Binding Proteins, Sequence Homology, Amino Acid, biology, Effector, Compound eye, Protein Structure, Tertiary, Cell biology, Enzyme Activation, Amino Acid Substitution, ras Proteins, biology.protein, Drosophila, Ras superfamily, Protein Binding, Signal Transduction, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ef849ffcfe5426e699a622ee26d14d
https://doi.org/10.1002/dvdy.20346

المؤلفون: Alan Lin, Vangipuram S. Rangan, Nestor X. Barrezueta, Laurel Vana, Paul D. Wes, Magdalena Nitla, Angela Cacace, Stefanie Keenan, Bin Zhang, Bradley Snyder, Nina Hoque, John Q. Trojanowski, Donna M. Barten, Jere E. Meredith, Ling Yang, Charles F. Albright, Craig Polson, Lynn B. DeCarr, Gregg Hirschfeld, Virginia M.-Y. Lee, Michael K. Ahlijanian, Gregory W. Cadelina, Kurt R. Brunden, Nino Devidze, Sethu Sankaranarayanan, Yang Cao

المصدر: PLoS ONE, Vol 10, Iss 5, p e0125614 (2015)
PLoS ONE

مصطلحات موضوعية: Genetically modified mouse, Male, Pathology, medicine.medical_specialty, Tau protein, Primary Cell Culture, Hippocampus, lcsh:Medicine, Mice, Transgenic, tau Proteins, Biology, Mice, Alzheimer Disease, mental disorders, medicine, Animals, lcsh:Science, Cerebral Cortex, Neurons, Multidisciplinary, lcsh:R, Immunization, Passive, Antibodies, Monoclonal, Entorhinal cortex, medicine.disease, Phosphoproteins, Recombinant Proteins, Disease Models, Animal, medicine.anatomical_structure, Treatment Outcome, Gene Expression Regulation, Cerebral cortex, biology.protein, Exploratory Behavior, lcsh:Q, Neuron, Tauopathy, Alzheimer's disease, Cognition Disorders, Signal Transduction, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0999b05b344335c86afebdbd6af76f99
http://europepmc.org/articles/PMC4416899?pdf=render

المؤلفون: Cornelia I. Bargmann, Paul D. Wes

المصدر: Nature. 410:698-701

مصطلحات موضوعية: Olfactory system, Mutant, medicine.disease_cause, Olfactory Receptor Neurons, parasitic diseases, medicine, Animals, Allele, Caenorhabditis elegans, Mutation, Multidisciplinary, biology, Chemotaxis, fungi, food and beverages, Anatomy, biology.organism_classification, Butanones, Cell biology, Smell, Thiazoles, medicine.anatomical_structure, nervous system, Odor, Benzaldehydes, Odorants, Neuron

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc80c7261c901e3109610f750e7b55e9
https://doi.org/10.1038/35070581

المؤلفون: Craig Montell, Paul D. Wes, Fred Chien, Hong-Sheng Li, Xian Zhong Shawn Xu, Stephen K. Doberstein

المصدر: Nature Neuroscience. 2:447-453

مصطلحات موضوعية: Myosin Heavy Chains, General Neuroscience, Mutant, PDZ domain, Myosin III, Biology, Subcellular localization, Rhabdomere, Cell biology, Mutation, Organelle, Animals, Drosophila Proteins, Drosophila, Photoreceptor Cells, Invertebrate, Binding site, Eye Proteins, Protein Kinases, Vision, Ocular, Protein Binding, Visual phototransduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8024cc813569f604269e9582c23f1d9
https://doi.org/10.1038/8116

المؤلفون: Paul D. Wes, Mujun Yu, Stewart Morgan, Hua Chen, Yuru Liu, Hong-Sheng Li, Xian Zhong Shawn Xu, Craig Montell

المصدر: Journal of Biological Chemistry. 273:31297-31307

مصطلحات موضوعية: GTPase-activating protein, Calmodulin, Ubiquitin-Protein Ligases, rab3 GTP-Binding Proteins, Molecular Sequence Data, Genes, Insect, GTPase, Biology, Neurotransmission, Synaptic Transmission, Biochemistry, Retina, chemistry.chemical_compound, Species Specificity, GTP-Binding Proteins, Animals, Drosophila Proteins, Amino Acid Sequence, RNA, Messenger, Selection, Genetic, Molecular Biology, Conserved Sequence, Ion channel, Sequence Homology, Amino Acid, Retinal, Cell Biology, Cell biology, chemistry, Calcium-Calmodulin-Dependent Protein Kinases, biology.protein, Calmodulin-Binding Proteins, Drosophila, Rab, Cell Adhesion Molecules, Visual phototransduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d6a408c83c1f2adaec7eaf6118104e
https://doi.org/10.1074/jbc.273.47.31297

المؤلفون: Dario Doller, Paul D. Wes, Thomas Möller

المصدر: Pathological Potential of Neuroglia ISBN: 9781493909735

مصطلحات موضوعية: Engineering, Knowledge management, Consolidation (business), Work (electrical), Process (engineering), business.industry, Isolation (psychology), Disease, Biology, business, Productivity, Variety (cybernetics), Pharmaceutical industry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::20a539a545cc8f63c15f1b67f6d1b85b
https://doi.org/10.1007/978-1-4939-0974-2_9

المؤلفون: Michelle R. Tsukamoto, David Cheng, Maya A. Koike, Frank M. LaFerla, Masashi Kitazawa, Paul D. Wes, David H. Cribbs, Vitaly Vasilevko

المصدر: Journal of immunology (Baltimore, Md. : 1950). 187(12)

مصطلحات موضوعية: Male, medicine.medical_treatment, Immunology, Interleukin-1beta, Inflammation, Mice, Transgenic, tau Proteins, S100 Calcium Binding Protein beta Subunit, Biology, Article, Proinflammatory cytokine, Mice, Alzheimer Disease, Cell Line, Tumor, medicine, Immunology and Allergy, Animals, Humans, Nerve Growth Factors, Cells, Cultured, beta Catenin, Neurons, Kinase, Cyclin-dependent kinase 5, Neurodegeneration, S100 Proteins, Wnt signaling pathway, NF-kappa B, Receptors, Interleukin-1, medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, Cytokine, Catenin, Female, medicine.symptom, Cognition Disorders, Neuroscience, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b87bf73a56a28b34f5e06386cf7cff48
https://pubmed.ncbi.nlm.nih.gov/22095718