المؤلفون: George P. Vlasuk, Ann L. Scott, Patricia K. Lumma, Victor M. Garsky, Raymond J. Winquist, Patricia B. Bunting

مصطلحات موضوعية: medicine.medical_specialty, Endocrinology, Internal medicine, medicine, Endothelin receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fa54ba72506962ac9f3e22c199d6ca53
https://doi.org/10.1159/000418351

المؤلفون: K J Stauffer, Victor M. Garsky, N S Rotberg, David C. Heimbrook, Hans E. Huber, R J Wegrzyn, Oliff Allen I, Raymond E. Jones, Patricia K. Lumma

المصدر: Journal of Biological Chemistry. 267:908-912

مصطلحات موضوعية: chemistry.chemical_classification, Binding protein, Ligand binding assay, Peptide, Cell Biology, Methylation, Plasma protein binding, Biology, Biochemistry, Molecular biology, Retinoblastoma-like protein 1, chemistry, Protein A/G, biology.protein, Protein G, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c95c510c8b3180d142aa8ea0eb091bb6
https://doi.org/10.1016/s0021-9258(18)48370-6

المؤلفون: Gautam Sanyal, Patricia K. Lumma, Jean Baum, Yuan Chen, Steven M. Pitzenberger, Victor M. Garsky

المصدر: Biochemistry. 30:11625-11636

مصطلحات موضوعية: chemistry.chemical_classification, Circular dichroism, Magnetic Resonance Spectroscopy, Proton, Protein Conformation, Circular Dichroism, Molecular Sequence Data, Analytical chemistry, Viper Venoms, Nuclear Overhauser effect, Hydrogen-Ion Concentration, Antiparallel (biochemistry), Biochemistry, Amino acid, Crystallography, chemistry.chemical_compound, chemistry, Amide, Proton NMR, Intercellular Signaling Peptides and Proteins, Spectrophotometry, Ultraviolet, Amino Acid Sequence, Protons, Peptides, Protein secondary structure

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf7ca4e146d89fe0a1131b867e3ae5e0
https://doi.org/10.1021/bi00114a004

المؤلفون: Ronald J. Shebuski, Denise Ramjit, Victor M. Garsky, Gary R. Sitko, Patricia K. Lumma

المصدر: Thrombosis and Haemostasis. 64:576-581

مصطلحات موضوعية: medicine.medical_specialty, medicine.diagnostic_test, business.industry, Venom, Hematology, Pharmacology, medicine.disease, Thrombosis, Surgery, In vivo, Bleeding time, Antithrombotic, medicine, Platelet, Thrombus, business, Ex vivo

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0cca000ddb21b62ef896ad4045af1cff
https://doi.org/10.1055/s-0038-1647361

المؤلفون: Roger M. Freidinger, Patricia K. Lumma, Bradley K. Wong, Oliff Allen I, Jiunn H. Lin, Stephen F. Brady, Jenny Wai, Joseph M. Pawluczyk, Cynthia Miller-Stein, Dong-Mei Feng, Deborah Defeo-Jones, Raymond E. Jones, Victor M. Garsky

المصدر: Journal of medicinal chemistry. 45(21)

مصطلحات موضوعية: Male, medicine.medical_treatment, Mice, Nude, Antineoplastic Agents, Vinblastine, Prostate cancer, Mice, Structure-Activity Relationship, Nude mouse, In vivo, Drug Discovery, medicine, Tumor Cells, Cultured, Animals, Humans, Doxorubicin, Prodrugs, Chemotherapy, biology, Chemistry, Prostatic Neoplasms, biology.organism_classification, medicine.disease, Prostate-specific antigen, Immunology, Cancer research, Molecular Medicine, Antimitotic Agent, Drug Screening Assays, Antitumor, Oligopeptides, Neoplasm Transplantation, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8121f543342ffa69ea493de198bb74c
https://pubmed.ncbi.nlm.nih.gov/12361397

المؤلفون: Roger M. Freidinger, Patricia K. Lumma, Ramjit Hg, Deborah Defeo-Jones, Mohinder K. Sardana, Jenny Wai, Oliff Allen I, Raymond E. Jones, Victor M. Garsky, Dong-Mei Feng

المصدر: Journal of medicinal chemistry. 44(24)

مصطلحات موضوعية: Male, medicine.medical_specialty, Transplantation, Heterologous, Mice, Nude, Antineoplastic Agents, urologic and male genital diseases, Mass Spectrometry, Prostate cancer, Mice, Structure-Activity Relationship, Therapeutic index, Prostate, Internal medicine, Drug Discovery, LNCaP, medicine, Tumor Cells, Cultured, Animals, Humans, Doxorubicin, Prodrugs, Antibiotics, Antineoplastic, Chemistry, Prostatic Neoplasms, Prodrug, Prostate-Specific Antigen, medicine.disease, Peptide Fragments, Prostate-specific antigen, Endocrinology, medicine.anatomical_structure, Cancer cell, Cancer research, Molecular Medicine, Drug Screening Assays, Antitumor, Oligopeptides, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e2b3ba2ef6235523f30eefaa1ebb41
https://pubmed.ncbi.nlm.nih.gov/11708923

المؤلفون: Oliff Allen I, Patricia K. Lumma, Ramjit Hg, Mohinder K. Sardana, Victor M. Garsky, Jenny Wai, Bradley K. Wong, Roger M. Freidinger, Raymond E. Jones, Deborah Defeo-Jones, Dong-Mei Feng

المصدر: Peptides: The Wave of the Future ISBN: 9789401039055

مصطلحات موضوعية: chemistry.chemical_classification, business.industry, Cancer, Peptide, Disease, Prodrug, medicine.disease, Prostate cancer, Prostate-specific antigen, medicine.anatomical_structure, chemistry, Prostate, medicine, Cancer research, Doxorubicin, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b4e4f213c476ad37eb88ad68404cc2f3
https://doi.org/10.1007/978-94-010-0464-0_300

المؤلفون: Roger M. Freidinger, Joel R. Huff, E T Senderak, Sherri L. Motzel, Karen R. Leander, M.J. van Zwieten, Bradley K. Wong, Dong-Mei Feng, A Oliff, Victor M. Garsky, T Bolyar, Deborah Defeo-Jones, Kevin P. Keenan, D M Kiefer, E M McAvoy, Jenny Wai, Patricia K. Lumma, Kathleen M. Haskell, Jiunn H. Lin, Raymond E. Jones

المصدر: Nature medicine. 6(11)

مصطلحات موضوعية: Male, medicine.medical_specialty, Mice, Nude, General Biochemistry, Genetics and Molecular Biology, Mice, Antigen, In vivo, Prostate, Internal medicine, medicine, Tumor Cells, Cultured, Cytotoxic T cell, Animals, Humans, Doxorubicin, Prodrugs, Tissue Distribution, business.industry, Cancer, Prostatic Neoplasms, General Medicine, Prostate-Specific Antigen, medicine.disease, Xenograft Model Antitumor Assays, Prostate-specific antigen, Endocrinology, medicine.anatomical_structure, Cancer cell, Cancer research, business, Oligopeptides, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f0e7f6c5fa0f534ea45ece741c53b9
https://pubmed.ncbi.nlm.nih.gov/11062536

المؤلفون: George P. Vlasuk, Elka M. Nutt, Christopher T. Dunwiddie, Lloyd Waxman, Kathryn J. Hofmann, Neeper Michael P, Patricia K. Lumma, Donna E. Smith, Victor M. Garsky

المصدر: Biochemistry. 31(48)

مصطلحات موضوعية: medicine.drug_mechanism_of_action, Stereochemistry, Protein Conformation, Factor Xa Inhibitor, Molecular Sequence Data, Peptide, Cleavage (embryo), Biochemistry, law.invention, Arthropod Proteins, Ticks, law, medicine, Escherichia coli, Animals, Humans, Amino Acid Sequence, Cloning, Molecular, Site-directed mutagenesis, chemistry.chemical_classification, biology, Sequence Homology, Amino Acid, Chemistry, Recombinant Proteins, Amino acid, Kinetics, Enzyme, Carbohydrate Sequence, Enzyme inhibitor, Recombinant DNA, biology.protein, Mutagenesis, Site-Directed, Intercellular Signaling Peptides and Proteins, Prothrombin, Peptides, Factor Xa Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8314d5fef453523a45f7c4ee5606299d
https://pubmed.ncbi.nlm.nih.gov/1457408

المؤلفون: Victor M. Garsky, Patricia K. Lumma, Lloyd Waxman, George P. Vlasuk, James A. Ryan, Daniel F. Veber, Roger M. Freidinger

المصدر: Peptides ISBN: 9789401050050

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bc88ce2fe48f91e3777709d444dc4e2f
https://doi.org/10.1007/978-94-011-2264-1_368

المؤلفون: Neeper Michael P, Kathryn J. Hofmann, George P. Vlasuk, Patricia K. Lumma, Elka M. Nutt, Victor M. Garsky, Lloyd Waxman, Donna E. Smith, Christopher T. Dunwiddie

المصدر: Biochemistry. 32:3196-3196

مصطلحات موضوعية: chemistry.chemical_classification, Enzyme, Biochemistry, medicine.drug_mechanism_of_action, chemistry, Factor Xa Inhibitor, medicine, Identification (biology), Biology, Tick anticoagulant peptide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a858b8c8ab9150374aa0dffd10aa7b3b
https://doi.org/10.1021/bi00063a036

المؤلفون: Steven M. Pitzenberger, Robert J. Gould, Patricia K. Lumma, Daniel F. Veber, Victor M. Garsky, Roger M. Freidinger, William C. Randall, Paul A. Friedman

المصدر: Proceedings of the National Academy of Sciences. 86:4022-4026

مصطلحات موضوعية: chemistry.chemical_classification, Multidisciplinary, Tetrapeptide, Protein Conformation, Chemistry, Stereochemistry, Circular Dichroism, Molecular Sequence Data, Peptide, Biological activity, Viper Venoms, Amino acid, Structure-Activity Relationship, Biochemistry, Humans, Intercellular Signaling Peptides and Proteins, Platelet aggregation inhibitor, Structure–activity relationship, Indicators and Reagents, Amino Acid Sequence, Binding site, Peptides, Peptide sequence, Platelet Aggregation Inhibitors, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::800b76a6fdcac739c829e0d749ae43d4
https://doi.org/10.1073/pnas.86.11.4022

المؤلفون: Brian T. Phillips, Patricia K. Lumma, David A. Claremon

المصدر: ChemInform. 18

مصطلحات موضوعية: chemistry.chemical_classification, Chemistry, Organic chemistry, General Medicine, Aldehyde

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::26cbb89f0b548939f7ab90454c546d4b
https://doi.org/10.1002/chin.198720077

المؤلفون: Patricia K. Lumma, Raymond J. Winquist, Patricia B. Bunting, Timothy L. Schofield, Victor M. Garsky

المصدر: European journal of pharmacology. 163(1)

مصطلحات موضوعية: Male, medicine.medical_specialty, Endothelium, Hemodynamics, Vasodilation, Blood Pressure, Rats, Inbred WKY, Afterload, Heart Rate, Internal medicine, Rats, Inbred SHR, Heart rate, medicine, Animals, cardiovascular diseases, Pharmacology, business.industry, Endothelins, Rats, Blood pressure, Endocrinology, medicine.anatomical_structure, cardiovascular system, medicine.symptom, business, Endothelin receptor, Peptides, Vasoconstriction, circulatory and respiratory physiology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5ee24cba0362009b1150b2426e0e50
https://pubmed.ncbi.nlm.nih.gov/2663529

المؤلفون: R. J. Winquist, Patricia K. Lumma, David E. McClure, David A. Claremon, S. A. Rosenthal, Gregory J. Kaczorowski, E. P. Faison, John J. Baldwin, Graham M. Smith, M. J. Trumble

المصدر: ChemInform. 18

مصطلحات موضوعية: Nitrendipine, Chemistry, Stereochemistry, medicine, General Medicine, Calcium entry, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3468bdbeac6034577f60fe408ddaa3c3
https://doi.org/10.1002/chin.198737259

المؤلفون: Paul L. Darke, Terrence M. Ciccarone, Patricia K. Lumma, Roger M. Freidinger, Victor M. Garsky, Irving S. Sigal, Stephen F. Brady, Daniel F. Veber, Ruth F. Nutt, Chih-Tai Leu

المصدر: Biochemical and biophysical research communications. 156(1)

مصطلحات موضوعية: Proteases, medicine.drug_class, viruses, medicine.medical_treatment, Biophysics, Retroviridae Proteins, Gene Products, gag, Biology, Cleavage (embryo), Biochemistry, Virus, Substrate Specificity, HIV-1 protease, medicine, Amino Acid Sequence, Molecular Biology, Peptide sequence, Antigens, Viral, chemistry.chemical_classification, Protease, Hydrolysis, Cell Biology, Kinetics, Enzyme, chemistry, biology.protein, HIV-1, Antiviral drug, Peptide Hydrolases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e472e5f6e0b9493f52d6ccad48cb888
https://pubmed.ncbi.nlm.nih.gov/3052448

المؤلفون: Raymond J. Winquist, Patricia K. Lumma, Gregory J. Kaczorowski, Mayme J. Trumble, Baldwin John J, David A. Claremon, Seth A. Rosenthal, Elizabeth P. Faison, Graham M. Smith, David E. McClure

المصدر: Journal of medicinal chemistry. 30(4)

مصطلحات موضوعية: Male, Dihydropyridines, Contraction (grammar), Chemical Phenomena, Stereochemistry, Pyridines, Swine, chemistry.chemical_element, Calcium, Ion Channels, Structure-Activity Relationship, Sarcolemma, Nitrendipine, Heterocyclic Compounds, Drug Discovery, medicine, Animals, Receptor, Aorta, Dose-Response Relationship, Drug, Terpenes, Ligand binding assay, Dihydropyridine, Biological activity, Rats, Inbred Strains, Calcium Channel Blockers, Rats, Chemistry, Membrane, chemistry, Molecular Medicine, medicine.drug, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a481d9e952ce12927b48f5580dd08e40
https://pubmed.ncbi.nlm.nih.gov/2435904

المؤلفون: Patricia K. Lumma, Brian T. Phillips, David A. Claremon

المصدر: Journal of the American Chemical Society. 108:8265-8266

مصطلحات موضوعية: chemistry.chemical_classification, chemistry.chemical_compound, Colloid and Surface Chemistry, chemistry, Hydrazone, Organic chemistry, Alcohol, General Chemistry, Aliphatic compound, Biochemistry, Aldehyde, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f70bd97ab6c500004f7c861d0de47cdc
https://doi.org/10.1021/ja00286a027