المؤلفون: Alex L. Wilkinson, Megan E. Bannister, Ayla O’Keeffe, Chris J. Weston, Patricia F. Lalor, Shishir Shetty, Daniel A. Patten

المصدر: STAR Protocols, Vol 5, Iss 4, Pp 103431- (2024)

مصطلحات موضوعية: Cell isolation, Cell-based Assays, Immunology, Science (General), Q1-390

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666166724005963; https://doaj.org/toc/2666-1667

URL الوصول: https://doaj.org/article/a87a87d5e3344a64abddf92f3ef34a51

المؤلفون: Paul Horn, Jenny Norlin, Kasper Almholt, Birgitte M Viuff, Elisabeth D Galsgaard, Andreas Hald, Franziska Zosel, Helle Demuth, Svend Poulsen, Peder L Norby, Morten G Rasch, Mogens Vyberg, Jan Fleckner, Mikkel Parsberg Werge, Lise Lotte Gluud, Marco R Rink, Emma Shepherd, Ellie Northall, Patricia F Lalor, Chris J Weston, Morten Fog-Tonnesen, Philip N Newsome

المصدر: eLife, Vol 13 (2024)

مصطلحات موضوعية: bone morphogenetic proteins, Gremlin-1, liver fibrosis, metabolic dysfunction-associated steatotic liver disease, metabolic dysfunction-associated steatohepatitis, NAFLD, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/95185; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/26db31e3cfc948118f0e0cdf01eb4818

المؤلفون: Reenam Khan, Shees Salman, Laura Harford, Lozan Sheriff, Jon Hazeldine, Neil Rajoriya, Philip N. Newsome, Patricia F. Lalor

المصدر: Frontiers in Immunology, Vol 15 (2024)

مصطلحات موضوعية: cirrhosis, neutrophil, monocyte, alcohol, hepatitis, human, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1330536/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/8a9e26786c094563b76955e229ab6afb

المؤلفون: Abhishek Chauhan, Lozan Sheriff, Mohammed T. Hussain, Gwilym J. Webb, Daniel A. Patten, Emma L. Shepherd, Robert Shaw, Christopher J. Weston, Debashis Haldar, Samuel Bourke, Rajan Bhandari, Stephanie Watson, David H. Adams, Steve P. Watson, Patricia F. Lalor

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/a6f8dbdcb34b42c0a82ada447cf8eac9

المؤلفون: Patricia F. Lalor, Thomas Huser, Leo A. van Grunsven

المصدر: Frontiers in Physiology, Vol 13 (2022)

مصطلحات موضوعية: sinusoidal endothelial cell, liver, chronic liver damage, scavenger receptor, super-resolution imaging, gene expression, Physiology, QP1-981

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2022.869473/full; https://doaj.org/toc/1664-042X

URL الوصول: https://doaj.org/article/937f548244e84254a493957538d52085

المؤلفون: Bethany H. James, Pantelitsa Papakyriacou, Matthew J. Gardener, Louise Gliddon, Christopher J. Weston, Patricia F. Lalor

المصدر: Frontiers in Physiology, Vol 12 (2022)

مصطلحات موضوعية: liver, endothelium, antibody, therapy, disease, Physiology, QP1-981

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2021.753833/full; https://doaj.org/toc/1664-042X

URL الوصول: https://doaj.org/article/46208750e7324e8cb8981fe921bbaef2

المؤلفون: Emma L. Shepherd, Raquel Saborano, Ellie Northall, Kae Matsuda, Hitomi Ogino, Hiroaki Yashiro, Jason Pickens, Ryan E. Feaver, Banumathi K. Cole, Stephen A. Hoang, Mark J. Lawson, Matthew Olson, Robert A. Figler, John E. Reardon, Nobuhiro Nishigaki, Brian R. Wamhoff, Ulrich L. Günther, Gideon Hirschfield, Derek M. Erion, Patricia F. Lalor

المصدر: JHEP Reports, Vol 3, Iss 2, Pp 100217- (2021)

مصطلحات موضوعية: NAFLD, Metabolism, Fructose, Fibrosis, Treatment, NASH, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555920301518; https://doaj.org/toc/2589-5559

URL الوصول: https://doaj.org/article/4340ddc01197436fbd613f61ff255144

المؤلفون: Lozan Sheriff, Patricia F. Lalor

المصدر: Livers; Volume 1; Issue 2; Pages: 68-81

مصطلحات موضوعية: NAFLD, ALD, steatosis, NLRP3, inflammasome

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/livers1020007

الاتاحة: https://doi.org/10.3390/livers1020007

المؤلفون: Lozan Sheriff, Reenam S. Khan, Raquel Saborano, Richard Wilkin, Nguyet-Thin Luu, Ulrich L. Gunther, Stefan G. Hubscher, Philip N. Newsome, Patricia F. Lalor

المصدر: Disease Models & Mechanisms, Vol 13, Iss 12 (2020)

مصطلحات موضوعية: alcoholic hepatitis, inflammation, fibrogenesis, steatosis, murine, Medicine, Pathology, RB1-214

وصف الملف: electronic resource

Relation: http://dmm.biologists.org/content/13/12/dmm046383; https://doaj.org/toc/1754-8403; https://doaj.org/toc/1754-8411

URL الوصول: https://doaj.org/article/7c847439e4524eaa9d2cb019ba199e50

المؤلفون: Abhilok Garg, Sheeba Khan, N. Luu, Davies J. Nicholas, Victoria Day, Andrew L. King, Janine Fear, Patricia F. Lalor, Philip N. Newsome

المصدر: Journal of Cellular and Molecular Medicine. 27:864-878

مصطلحات موضوعية: Molecular Medicine, Cell Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ea899e5a97a6822f25e5d20384141bf0
https://doi.org/10.1111/jcmm.17698

المؤلفون: Sheeba Khan, Sara Mahgoub, Nada Fallatah, Patricia F Lalor, Philip N Newsome

المصدر: Stem Cells.

مصطلحات موضوعية: Molecular Medicine, Cell Biology, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c4a8ae3afa1d17953d37f70c19f56a95
https://doi.org/10.1093/stmcls/sxad029

المؤلفون: Emma L. Shepherd, Ellie Northall, Pantelitsa Papakyriacou, Karolina Safranska, Karen K. Sorensen, Patricia F. Lalor

المصدر: Methods in Molecular Biology ISBN: 9781071632062

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::155cfb3d34eca379d08a6d33078a1266
https://doi.org/10.1007/978-1-0716-3207-9_14

المؤلفون: Raquel Saborano, Emma Shepherd, Ulrich L. Günther, Patricia F. Lalor

المصدر: Methods in Molecular Biology ISBN: 9781071632468

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::afe2a7fd07d3fdc25e15ffd2955d24a1
https://doi.org/10.1007/978-1-0716-3247-5_13

المؤلفون: Brandon A. Coke, Emma L. Shepherd, Nikolas J. Hodges, Kyriaki Chatzi, Timothy Schulz-utermoehl, Nicholas J. Coltman, Patricia F. Lalor

المصدر: Toxicology Letters. 345:34-45

مصطلحات موضوعية: 0301 basic medicine, Time Factors, Animal Testing Alternatives, Toxicology, medicine.disease_cause, Gene Expression Regulation, Enzymologic, Activation, Metabolic, Histones, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Spheroids, Cellular, Cellular stress response, Benzo(a)pyrene, medicine, Humans, Phosphorylation, Anthracenes, Chemistry, Imidazoles, Spheroid, Hep G2 Cells, General Medicine, Molecular biology, 4-Nitroquinoline-1-oxide, In vitro, Comet assay, 030104 developmental biology, Liver, embryonic structures, Hepatocytes, Comet Assay, Liver function, GADD45A, 030217 neurology & neurosurgery, Genotoxicity, DNA Damage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39c90cd3f26fe3ad2da53b92f73515f
https://doi.org/10.1016/j.toxlet.2021.04.004

المؤلفون: Sumera Karim, Philip N. Newsome, Emma L. Shepherd, Patricia F. Lalor

المصدر: World Journal of Hepatology. 12:931-948

مصطلحات موضوعية: education.field_of_study, Hepatology, biology, AOC3, business.industry, Insulin, medicine.medical_treatment, Fatty liver, Population, Pharmacology, medicine.disease, respiratory tract diseases, Proinflammatory cytokine, 03 medical and health sciences, Insulin receptor, 0302 clinical medicine, Insulin resistance, 030220 oncology & carcinogenesis, medicine, biology.protein, 030211 gastroenterology & hepatology, Steatosis, education, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c025fdeba8e09d888219dbecadb15147
https://doi.org/10.4254/wjh.v12.i11.931

المؤلفون: Dominik Pfister, Moritz Peiseler, Roland Rad, Monika Julia Wolf, Suchira Gallage, Elena Kotsiliti, Caroline L. Wilson, Tjeerd P. Sijmonsma, Nabil Djouder, Marco Prinz, Daniela C. Kroy, Frank Tacke, Jerry Ware, Adnan Ali, Roser Pinyol, Mike Notohamiprodjo, Tracy O'Connor, Christopher J. Weston, Paul Kubes, Bas G.J. Surewaard, Percy A. Knolle, Achim Weber, Michael D. Milsom, Patrick M. Helbling, Daniel Dauch, Tobias Geisler, Mohsen Malehmir, Carsten Deppermann, Alexander Olkus, Marcel Rall, Hellmut G. Augustin, Lars Zender, Julia Volz, Ana Teijeiro, César Nombela-Arrieta, Malte N. Bongers, Valentina Leone, Mathias Heikenwalder, Matthias S. Matter, Dominic J. Withers, Lozan Sheriff, Alexandros Vegiopoulos, Oliver Krenkel, Oliver Borst, Patricia F. Lalor, Jack Leslie, Anahita Rafiei, Florian Baku, David H. Adams, Adam J. Rose, Bernhard Nieswandt, Thomas Engleitner, Hannah K. Drescher, Dominik Rath, Natasha S Anstee, Marlene Kohlhepp, Marc E. Healy, Marta Szydlowska, Meinrad Gawaz, Ruzhica Bogeska, Kristian Unger, Donato Inverso, David Stegner, Martina Hinterleitner, Derek A. Mann, Josep M. Llovet

المساهمون: Medical Research Council, Wellcome Trust

المصدر: Nature Medicine

مصطلحات موضوعية: 0301 basic medicine, Platelet Aggregation, NF-KAPPA-B, Research & Experimental Medicine, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, HEPATOCELLULAR-CARCINOMA, Platelet, Hyaluronic Acid, 11 Medical and Health Sciences, Liver Neoplasms, Fatty liver, Platelet Glycoprotein GPIb-IX Complex, MOUSE MODEL, General Medicine, 3. Good health, Hyaluronan Receptors, Medicine, Research & Experimental, Liver, 030220 oncology & carcinogenesis, Cytokines, Platelet aggregation inhibitor, GLYCOPROTEIN-VI, Liver cancer, Life Sciences & Biomedicine, Blood Platelets, Biochemistry & Molecular Biology, Kupffer Cells, FACTOR BINDING, Immunology, Mice, Transgenic, Cytoplasmic Granules, digestive system, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, INFLAMMATION, medicine, Animals, Humans, Endothelium, Platelet activation, Science & Technology, IN-VIVO DEPLETION, ANTIPLATELET THERAPY, Platelet Count, business.industry, SET ENRICHMENT ANALYSIS, Body Weight, Cell Biology, medicine.disease, digestive system diseases, 030104 developmental biology, Hepatocytes, Cancer research, Steatohepatitis, Steatosis, business, Platelet Aggregation Inhibitors, CAUSES NONALCOHOLIC STEATOHEPATITIS

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020302d3255a56f374e4d918ceb97c5d
https://doi.org/10.1038/s41591-019-0379-5

المؤلفون: Ellie Northall, Banumathi K. Cole, John E. Reardon, Brian R. Wamhoff, Matthew W. Olson, Stephen A. Hoang, Kae Matsuda, Ulrich L. Günther, Mark J. Lawson, Ryan E. Feaver, Jason Pickens, Patricia F. Lalor, Raquel Saborano, Robert A. Figler, Hiroaki Yashiro, Derek M. Erion, Hitomi Ogino, Emma L. Shepherd, Gideon M. Hirschfield, Nobuhiro Nishigaki

المصدر: JHEP Reports, Vol 3, Iss 2, Pp 100217-(2021)
JHEP Reports

مصطلحات موضوعية: ALD, alcohol-related cirrhosis, IGF, insulin-like growth factor, PDGF, platelet-derived growth factor, chemistry.chemical_compound, Fibrosis, AST, aspartate transaminase, Immunology and Allergy, Glycolysis, Liver injury, G/F, glucose/fructose, biology, TG, triglyceride, Fatty liver, Gastroenterology, NASH, HSQC, heteronuclear single quantum coherence, CT, computed tomography, aLMF, activated liver myofibroblasts, HSCs, hepatic stellate cells, Research Article, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, ALT, alanine transaminase, NASH, non-alcoholic steatohepatitis, FIB4, fibrosis-4, DNL, de novo lipogenesis, Fructose, Internal medicine, NAFLD, Internal Medicine, medicine, TGFB, transforming growth factor beta, lcsh:RC799-869, APRI, AST to Platelet Ratio Index, NPCs, non-parenchymal cells, KO, knockout, Hepatology, business.industry, medicine.disease, WT, wild-type, KHK, ketohexokinase, HSECs, hepatic sinusoidal endothelial cells, Treatment, Endocrinology, PSC, primary sclerosing cholangitis, Metabolism, chemistry, Alanine transaminase, Hepatic stellate cell, biology.protein, BSA, bovine serum albumin, TIMP-1, Tissue Inhibitor of Matrix metalloproteinase-1, lcsh:Diseases of the digestive system. Gastroenterology, PBC, primary biliary cholangitis, Steatosis, business, BEC, biliary epithelial cells, LGLI, low glucose and insulin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e901d5e74295d49cc1586ef5be254e
http://www.sciencedirect.com/science/article/pii/S2589555920301518

المؤلفون: Reenam S. Khan, Philip N. Newsome, Lozan Sheriff, Ulrich L. Günther, Stefan G. Hübscher, Raquel Saborano, Richard Wilkin, Patricia F. Lalor, Nguyet-Thin Luu

المصدر: Disease Models & Mechanisms
article-version (VoR) Version of Record
Disease Models & Mechanisms, Vol 13, Iss 12 (2020)

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Alcoholic liver disease, Steatosis, NF-E2-Related Factor 2, Neuroscience (miscellaneous), lcsh:Medicine, Medicine (miscellaneous), Alcoholic hepatitis, Inflammation, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Pathogenesis, 03 medical and health sciences, 0302 clinical medicine, Immunology and Microbiology (miscellaneous), Internal medicine, lcsh:Pathology, medicine, Animals, Regeneration, Murine, Liver injury, Ethanol, business.industry, Hepatitis, Alcoholic, lcsh:R, medicine.disease, Dd, Fibrogenesis, Fatty Liver, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Hepatocyte, Hepatocytes, 030211 gastroenterology & hepatology, Female, medicine.symptom, business, Oxidative stress, lcsh:RB1-214, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c05a3203d66cbba62a3134f3ca2e2b
http://europepmc.org/articles/PMC7790192

المؤلفون: Emma L, Shepherd, Sumera, Karim, Philip N, Newsome, Patricia F, Lalor

المصدر: World Journal of Hepatology

مصطلحات موضوعية: Cell biology, Steatosis, Vascular adhesion protein-1, Hepatocyte, Basic Study, Lipid, respiratory tract diseases, Non-alcoholic fatty liver disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::fcd1927f110cce2e7701f65ca84a0e4c
https://pubmed.ncbi.nlm.nih.gov/33312420

المؤلفون: Patricia F. Lalor, Anna M. Randi, Neil Dufton, Abhishek Chauhan, Gwilym J. Webb, Justin C. Mason, Youwen Yang, Viktoria Kalna, Claire Peghaire, David H. Adams, Claudio Raimondi, Lourdes Osuna-Almagro, Graeme M. Birdsey

المصدر: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)

مصطلحات موضوعية: Male, Epithelial-Mesenchymal Transition, Science, Transcriptional regulatory elements, Liver fibrosis, General Physics and Astronomy, Down-Regulation, Smad2 Protein, Biology, Liver Cirrhosis, Experimental, General Biochemistry, Genetics and Molecular Biology, Etanercept, Smad1 Protein, End Stage Liver Disease, Mice, Transcriptional Regulator ERG, Transforming Growth Factor beta, Human Umbilical Vein Endothelial Cells, Animals, Humans, Smad3 Protein, lcsh:Science, Author Correction, Transcription factor, Carbon Tetrachloride, Tgfβ signalling, Cells, Cultured, Mice, Knockout, Oncogene Proteins, Multidisciplinary, Liver Cirrhosis, Biliary, Tumor Necrosis Factor-alpha, Endothelial Cells, General Chemistry, Fibrosis, Up-Regulation, Mice, Inbred C57BL, Mechanisms of disease, Liver, Cancer research, lcsh:Q, Female, Erg, Cell signalling, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe5ecf529b794e568c2738b7c3814677
http://europepmc.org/articles/PMC7058024