المؤلفون: Matthews, David R., Del Prato, Stefano, Mohan, Viswanathan, Mathieu, Chantal, Vencio, Sergio, Chan, Juliana C. N., Stumvoll, Michael, Paldanius, Päivi M.

المساهمون: HUS Children and Adolescents

مصطلحات موضوعية: glycaemic control, metformin, randomized trial, vildagliptin, FAILURE, ASIA, General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

Relation: Matthews , D R , Del Prato , S , Mohan , V , Mathieu , C , Vencio , S , Chan , J C N , Stumvoll , M & Paldanius , P M 2020 , ' Insights from VERIFY : Early Combination TherapyProvides Better Glycaemic Durability Than a StepwiseApproach in Newly Diagnosed Type2 Diabetes ' , Diabetes therapy , vol. 11 , pp. 2465–2476 . https://doi.org/10.1007/s13300-020-00926-7; http://hdl.handle.net/10138/338692; 0643024f-4c3a-49ec-95cc-e20b41a5eeee; 000572702300003

الاتاحة: http://hdl.handle.net/10138/338692

المؤلفون: Vencio, Sérgio, Manosalva, Juan P., Mathieu, Chantal, Proot, Pieter, Lozno, Hernan Y., Paldánius, Päivi M.

وصف الملف: application/pdf

Relation: Diabetology & Metabolic Syndrome. 2021 Jun 15;13(1):68; http://hdl.handle.net/10138/579968

الاتاحة: http://hdl.handle.net/10138/579968
https://doi.org/10.1186/s13098-021-00686-9

المؤلفون: Chan, Juliana C. N., Paldanius, Päivi M., Mathieu, Chantal, Stumvoll, Michael, Matthews, David R., Del Prato, Stefano

المساهمون: HUS Children and Adolescents, Clinicum, Children's Hospital, University of Helsinki, Helsinki University Hospital Area, CAMM - Research Program for Clinical and Molecular Metabolism, Research Programs Unit

مصطلحات موضوعية: glycaemic control, metformin, randomized trial, vildagliptin, FAILURE, ASIA, General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

Relation: Novartis; Chan , J C N , Paldanius , P M , Mathieu , C , Stumvoll , M , Matthews , D R & Del Prato , S 2021 , ' Early combination therapy delayed treatment escalation in newly diagnosed young-onset type 2 diabetes : A subanalysis of theVERIFYstudy ' , Diabetes, obesity and metabolism , vol. 23 , no. 1 , pp. 245-251 . https://doi.org/10.1111/dom.14192; http://hdl.handle.net/10138/334016; c41ab783-8cac-41d5-89f9-e339bf9f4b24; 000573355900001

الاتاحة: http://hdl.handle.net/10138/334016

المؤلفون: Yoo, Soon-Jib, Chang, Sang-Ah, Sohn, Tae Seo, Kwon, Hyuk-Sang, Lee, Jong Min, Moon, Sungdae, Proot, Pieter, Paldanius, Päivi M., Yoon, Kun Ho

المساهمون: HUS Children and Adolescents, Children's Hospital, Clinicum, CAMM - Research Program for Clinical and Molecular Metabolism

مصطلحات موضوعية: Diabetes mellitus, type 2, Drug therapy, combination, Glycated hemoglobin A, Korea, Metformin, Vildagliptin, GLUCOSE, ASIA, General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

Relation: Yoo , S-J , Chang , S-A , Sohn , T S , Kwon , H-S , Lee , J M , Moon , S , Proot , P , Paldanius , P M & Yoon , K H 2021 , ' Long-Term Glycaemic Durability of Early Combination Therapy Strategy versus Metformin Monotherapy in Korean Patients with Newly Diagnosed Type 2 Diabetes Mellitus ' , Diabetes & metabolism journal , vol. 45 , no. 6 , pp. 954-959 . https://doi.org/10.4093/dmj.2020.0173; http://hdl.handle.net/10138/338077; c0b34b5b-6f55-44da-8279-366fa18a8f45; 000726746100015

الاتاحة: http://hdl.handle.net/10138/338077

المؤلفون: Paldanius, Päivi M., Ivaska, Kaisa K., Mäkitie, Outi, Viljakainen, Heli

المساهمون: HUS Children and Adolescents, Children's Hospital, CAMM - Research Program for Clinical and Molecular Metabolism, Research Programs Unit, Clinicum, Lastentautien yksikkö, Department of Food and Nutrition

مصطلحات موضوعية: pediatric normative values, bone turnover markers, serum osteocalcin, urinary mid-fragment osteocalcin, sex and age-specific ranges, BONE-MINERAL DENSITY, BIOCHEMICAL MARKERS, REFERENCE INTERVALS, TURNOVER MARKERS, BODY-COMPOSITION, REFERENCE CURVES, METABOLISM, GROWTH, AGE, FRACTURES, Gynaecology and paediatrics

وصف الملف: application/pdf

Relation: This work was financially supported by the Foundation for Paediatric Research, the Academy of Finland, the Helsinki University Hospital research funds, the Sigrid Juselius Foundation, the Folkhalsan Research Foundation, and Turku University Foundation. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.; Paldanius , P M , Ivaska , K K , Mäkitie , O & Viljakainen , H 2021 , ' Serum and Urinary Osteocalcin in Healthy 7-to 19-Year-Old Finnish Children and Adolescents ' , Frontiers in pediatrics , vol. 9 . https://doi.org/10.3389/fped.2021.610227; ORCID: /0000-0002-7486-3437/work/102448498; ORCID: /0000-0002-4547-001X/work/155652007; http://hdl.handle.net/10138/335924; f6db67fd-6ee3-415c-a72d-1d2a0eff9bf6; 000696557200001

الاتاحة: http://hdl.handle.net/10138/335924

المؤلفون: Vencio, Sergio, Manosalva, Juan P., Mathieu, Chantal, Proot, Pieter, Lozno, Hernan Yupanqui, Paldanius, Päivi M.

المساهمون: HUS Children and Adolescents, Children's Hospital, Clinicum, CAMM - Research Program for Clinical and Molecular Metabolism, Research Programs Unit, University of Helsinki

مصطلحات موضوعية: Early combination, Latin America, Type 2 diabetes mellitus, Vildagliptin, GLYCEMIC CONTROL, CARE, HYPERGLYCEMIA, MONOTHERAPY, MANAGEMENT, MELLITUS, WOMEN, General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

Relation: PMP was the medical lead of the VERIFY study and employed by Novartis (till Jan 2020) and received grants from Juselius Foundation and UPM Biomedicals, outside the submitted work. CM, SV and YLH declare that they have no competing interests. PP and JMP are employed by and own stocks in Novartis. Study was funded by Novartis Pharma AG, Basel, Switzerland. The authors thank all the VERIFY study investigators from all sites of the Latin American countries, site personnel and patients who participated in this study. The investigators were Silvia Gorban de Lapertosa, Diego Aizenberg, Ines Palmira Bertolacci, Silvia In?s Orio, Federico Perez Manghi, Laura Maffei, Jorge Roberto Aiub, Maria Teresa Zanella, Carolina Jungers de Siqueira Chrisman, Freddy Goldberg Eliaschewitz, Jo?o Soares Felicio, Luis Henrique Santos Canani, Joao Lindolfo Cunha Borges, Maria Jose Jos? Ara?jo Gomes Cerqueira, Miguel Nasser Hissa, Emerson Cestari Marino, Jo?o Eduardo Nunes Salles, Rosa Ferreira dos Santos, Jaime Orlando Ibbara Gomez, Arturo Orduz Lopez, Fernando Manzur Jattin, Casimiro Velazco Espaillat, Dolores Mej?a, Juan Carlos Vargas, Sergio Bran, Clara Elizabeth Chang, Lorena Isabel Gracia Batres, Luis Ramirez, Guerrero Guerrero, Juan Pablo Moreira Diaz, Flor de Maria Ranchos Monterroso, Leobardo Sauque Reyna, Sergio Cesar Hernandez Jimenez, Guadalupe Morales Franco, Enrique Cuitlahuac Morales Villegas, Jorge Aldrete Velasco, Guillermo Fanghanel Salmon, Manuel Enrique Aguilera Real, Jose Villagordoa Mesa, Marilyn Donato, Pablo E. Fletcher Vasquez, Giselle Rodriguez, Angelica M. Valdivia Portugai, Cesar Manuel Delgado Butron, Jose Enrique Solis Villanueva, Miguel Eduardo Pinto Valdivia, Luis Alberto More, Luis Alberto Camacho Cosavalente, Luis Humberto Zapata Rincon. The authors also thank Shaswati Khan from Novartis Healthcare Pvt. Ltd., Hyderabad, India, for providing medical writing support for the manuscript, in accordance with Good Publication Practice guidelines. We are also grateful for the support of all those involved in the execution of this study. The study was presented as ePoster during the 80th American Diabetes Association congress 2020 held on June 12?16, 2020 in Chicago, USA; Vencio , S , Manosalva , J P , Mathieu , C , Proot , P , Lozno , H Y & Paldanius , P M 2021 , ' Exploring early combination strategy in Latin American patients with newly diagnosed type 2 diabetes : a sub-analysis of the VERIFY study ' , Diabetology & metabolic syndrome , vol. 13 , no. 1 , 68 . https://doi.org/10.1186/s13098-021-00686-9; http://hdl.handle.net/10138/333300; 1bd0349a-3cad-47fb-8d8c-56c3e902dcae; 000661910800001

الاتاحة: http://hdl.handle.net/10138/333300

المؤلفون: Matthews, David R., Paldanius, Päivi M., Stumvoll, Michael, Han, Jackie, Bader, Giovanni, Chiang, YannTong, Proot, Pieter, Del Prato, Stefano

المساهمون: HUS Children and Adolescents

مصطلحات موضوعية: glycaemic durability, randomized controlled trial, statistical analysis plan, type 2 diabetes mellitus, VERIFY study, vildagliptin, HOMEOSTASIS MODEL ASSESSMENT, BETA-CELL FUNCTION, INSULIN-RESISTANCE, GLYCEMIC CONTROL, DOUBLE-BLIND, TYPE-2, THERAPY, GLUCOSE, DURABILITY, ADJUSTMENT, General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

Relation: Novartis Pharmaceutical Corporation; Matthews , D R , Paldanius , P M , Stumvoll , M , Han , J , Bader , G , Chiang , Y , Proot , P & Del Prato , S 2019 , ' A pre-specified statistical analysis plan for the VERIFY study : Vildagliptin efficacy in combination with metformin for early treatment of T2DM ' , Diabetes, obesity and metabolism , vol. 21 , no. 10 , pp. 2240-2247 . https://doi.org/10.1111/dom.13800; http://hdl.handle.net/10138/327622; 93867ab0-df6f-4302-ab84-0ca847ce600d; 000473951000001

الاتاحة: http://hdl.handle.net/10138/327622

المؤلفون: Matthews, David R., Paldánius, Päivi M., Stumvoll, Michael, Han, Jackie, Bader, Giovanni, Chiang, YannTong, Proot, Pieter, Del Prato, Stefano

المساهمون: Novartis Pharmaceuticals Corporation

المصدر: Diabetes, Obesity and Metabolism ; volume 21, issue 10, page 2240-2247 ; ISSN 1462-8902 1463-1326

الاتاحة: http://dx.doi.org/10.1111/dom.13800
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fdom.13800
https://onlinelibrary.wiley.com/doi/pdf/10.1111/dom.13800
https://onlinelibrary.wiley.com/doi/full-xml/10.1111/dom.13800

المؤلفون: Kozlovski, Plamen, Fonseca, Marilia, Mohan, Viswanathan, Lukashevich, Valentina, Odawara, Masato, Paldánius, Päivi M., Kothny, Wolfgang

المساهمون: Novartis Pharma AG, Basel, Switzerland

المصدر: Diabetes, Obesity and Metabolism ; volume 19, issue 3, page 429-435 ; ISSN 1462-8902 1463-1326

الاتاحة: http://dx.doi.org/10.1111/dom.12844
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fdom.12844
http://onlinelibrary.wiley.com/wol1/doi/10.1111/dom.12844/fullpdf

المؤلفون: Brath, Helmut, Paldánius, Päivi M., Bader, Giovanni, Mathieu, Chantal

المساهمون: Novartis Pharma AG

المصدر: Diabetes Therapy ; volume 8, issue 4, page 829-836 ; ISSN 1869-6953 1869-6961

الاتاحة: http://dx.doi.org/10.1007/s13300-017-0276-1
http://link.springer.com/content/pdf/10.1007/s13300-017-0276-1.pdf
http://link.springer.com/article/10.1007/s13300-017-0276-1/fulltext.html

المؤلفون: Evans, Marc, Kozlovski, Plamen, Paldánius, Päivi M., Foley, James E., Bhosekar, Vaishali, Serban, Carmen, Avogaro, Angelo

المساهمون: Novartis

المصدر: Diabetes Therapy ; volume 9, issue 1, page 27-36 ; ISSN 1869-6953 1869-6961

الاتاحة: http://dx.doi.org/10.1007/s13300-017-0329-5
http://link.springer.com/content/pdf/10.1007/s13300-017-0329-5.pdf
http://link.springer.com/article/10.1007/s13300-017-0329-5/fulltext.html

المؤلفون: Vencio, Sérgio, Paldánius, Päivi M., Blüher, Matthias, Giannella-Neto, Daniel, Caiado-Vencio, Rafael, Strain, W. David

المساهمون: Novartis

المصدر: Diabetology & Metabolic Syndrome ; volume 9, issue 1 ; ISSN 1758-5996

الاتاحة: http://dx.doi.org/10.1186/s13098-017-0244-y
http://link.springer.com/content/pdf/10.1186/s13098-017-0244-y.pdf

المؤلفون: Thomas, Merlin C., Paldánius, Päivi M., Ayyagari, Rajeev, Ong, Siew Hwa, Groop, Per-Henrik

المساهمون: Novartis Pharma AG, Basel, Switzerland

المصدر: Diabetes Therapy ; volume 7, issue 3, page 439-454 ; ISSN 1869-6953 1869-6961

الاتاحة: http://dx.doi.org/10.1007/s13300-016-0189-4
http://link.springer.com/content/pdf/10.1007/s13300-016-0189-4.pdf
http://link.springer.com/article/10.1007/s13300-016-0189-4/fulltext.html

المؤلفون: Xavier, Cos Francesc, Bosi, Emanuele, Piatti, Piermarco, Paldánius, Päivi M

المصدر: Endocrine Abstracts ; ISSN 1479-6848

الاتاحة: http://dx.doi.org/10.1530/endoabs.73.pep2.4
http://www.endocrine-abstracts.org/ea/0073/ea0073pep2.4.htm

المؤلفون: Paldánius, Päivi M., Ivaska, Kaisa K., Hovi, Petteri, Andersson, Sture, Eriksson, Johan G., Väänänen, Kalervo, Kajantie, Eero, Mäkitie, Outi

المساهمون: Wagner, Bridget

المصدر: PLoS ONE ; volume 8, issue 5, page e63036 ; ISSN 1932-6203

الاتاحة: http://dx.doi.org/10.1371/journal.pone.0063036
http://dx.plos.org/10.1371/journal.pone.0063036

المؤلفون: Chan, Juliana C. N., Paldánius, Päivi M., Mathieu, Chantal, Stumvoll, Michael, Matthews, David R., Del Prato, Stefano

المساهمون: Novartis

المصدر: Diabetes, Obesity and Metabolism ; volume 23, issue 1, page 245-251 ; ISSN 1462-8902 1463-1326

الاتاحة: http://dx.doi.org/10.1111/dom.14192
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fdom.14192
https://onlinelibrary.wiley.com/doi/pdf/10.1111/dom.14192
https://onlinelibrary.wiley.com/doi/full-xml/10.1111/dom.14192

المؤلفون: Matthews, David R, Paldánius, Päivi M, Proot, Pieter, Chiang, YannTong, Stumvoll, Michael, Del Prato, Stefano

المصدر: The Lancet ; volume 394, issue 10208, page 1519-1529 ; ISSN 0140-6736

الاتاحة: http://dx.doi.org/10.1016/s0140-6736(19)32131-2
https://api.elsevier.com/content/article/PII:S0140673619321312?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0140673619321312?httpAccept=text/plain

المؤلفون: Soon-Jib Yoo, Sang-Ah Chang, Tae Seo Sohn, Hyuk-Sang Kwon, Jong Min Lee, Sungdae Moon, Proot, Pieter, Paldánius, Päivi M., Kun Ho Yoon

المصدر: Diabetes & Metabolism Journal; Nov2021, Vol. 45 Issue 6, p954-959, 6p

مصطلحات موضوعية: TYPE 2 diabetes, KOREANS, GLYCOSYLATED hemoglobin, TREATMENT failure, METFORMIN, DURABILITY

مصطلحات جغرافية: SOUTH Korea

المؤلفون: Brath, Helmut, Paldanius, Paeivi M, Bader, Giovanni, Mathieu, Chantal

Relation: Diabetes vol:66 pages:A323-A323; Scientific Sessions of the American-Diabetes-Association edition:77 location:San Diego: CA date:JUN 09-13, 2017; https://lirias.kuleuven.be/handle/123456789/593212

الاتاحة: https://lirias.kuleuven.be/handle/123456789/593212

المؤلفون: Benhalima, Katrien, Mathiesen, Elisabeth R., Paldanius, Päivi M., Mathieu, Chantal

المساهمون: Clinical Doctoral Scholarship of the academic fund of UZ Leuven

المصدر: Diabetes, Obesity and Metabolism ; volume 20, issue 10, page 2477-2480 ; ISSN 1462-8902 1463-1326

الاتاحة: http://dx.doi.org/10.1111/dom.13386
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fdom.13386
http://onlinelibrary.wiley.com/wol1/doi/10.1111/dom.13386/fullpdf