المؤلفون: Iff, Michael, Atz, Kenneth, id_orcid:0 000-0002-2628-1619, Isert, Clemens, id_orcid:0 000-0002-4176-7887, Pachon-Angona, Irene, Cotos, Leandro, Hilleke, Mattis, Hiss, Jan A., Schneider, Gisbert, id_orcid:0 000-0001-6706-1084

المصدر: RSC Advances, 14 (50)

وصف الملف: application/application/pdf

Relation: info:eu-repo/semantics/altIdentifier/wos/001358687900001; info:eu-repo/grantAgreement/SNF/Projekte MINT/182176; info:eu-repo/grantAgreement/SNF/Sinergia/202245; http://hdl.handle.net/20.500.11850/708165

الاتاحة: https://hdl.handle.net/20.500.11850/708165
https://doi.org/10.3929/ethz-b-000708165

المؤلفون: Pachón Angona, Irene, Bernard, Paul J., Simakov, Alexey, Maj, Maciej, Jozwiak, Krzysztof, Novotna, Anna, Lemke, Carina, Gütschow, Michael, Martin, Helene, Oset Gasque, María Jesús, Contelles, José Marco, Ismaili, Lhassane

مصطلحات موضوعية: Calcium channel inhibitors, Proteases inhibitors, Antioxidant response element, ORAC, Alzheimer’s disease, Farmacia, 24 Ciencias de la Vida

وصف الملف: application/pdf

Relation: Pachón-Angona, I.; Bernard, P.J.; Simakov, A.; Maj, M.; Jozwiak, K.; Novotna, A.; Lemke, C.; Gütschow, M.; Martin, H.; Oset-Gasque, M.-J.; et al. Design and Synthesis of Multi-Functional Ligands through Hantzsch Reaction: Targeting Ca2+ Channels, Activating Nrf2 and Possessing Cathepsin S Inhibitory, and Antioxidant Properties. Pharmaceutics 2024, 16, 121. https://doi.org/10.3390/pharmaceutics 16010121; https://hdl.handle.net/20.500.14352/111903

الاتاحة: https://hdl.handle.net/20.500.14352/111903
https://doi.org/10.3390/pharmaceutics16010121

المؤلفون: Moret, Michael, Pachon Angona, Irene, Cotos, Leandro, Yan, Shen, Atz, Kenneth, Brunner, Cyrill, Baumgartner, Martin, Grisoni, Francesca, Schneider, Gisbert

المصدر: Moret, Michael; Pachon Angona, Irene; Cotos, Leandro; Yan, Shen; Atz, Kenneth; Brunner, Cyrill; Baumgartner, Martin; Grisoni, Francesca; Schneider, Gisbert (2023). Leveraging molecular structure and bioactivity with chemical language models for de novo drug design. Nature Communications, 14(1):114.

مصطلحات موضوعية: Medical Clinic, Institute of Molecular Life Sciences, 570 Life sciences, biology, 610 Medicine & health

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/226966/1/PMID36611029_Moret_Nature_communictions_2022.pdf; https://www.zora.uzh.ch/id/eprint/226966/8/41467_2022_Article_35692.pdf; info:pmid/36611029; urn:issn:2041-1723

الاتاحة: https://www.zora.uzh.ch/id/eprint/226966/
https://www.zora.uzh.ch/id/eprint/226966/1/PMID36611029_Moret_Nature_communictions_2022.pdf
https://www.zora.uzh.ch/id/eprint/226966/8/41467_2022_Article_35692.pdf

المؤلفون: Pasquereau, Sébastien, Galais, Mathilde, Bellefroid, Maxime, Pachón Angona, Irene, Morot-Bizot, Stéphanie, Ismaili, Lhassane, Van Lint, Carine, Herbein, Georges

المصدر: Scientific reports, 12 (1

مصطلحات موضوعية: Sciences bio-médicales et agricoles, Humans, Coronavirus 229E, Human, SARS-CoV-2, RNA, Viral, COVID-19 Drug Treatment

وصف الملف: 1 full-text file(s): application/pdf

Relation: uri/info:doi/10.1038/s41598-022-24682-9; uri/info:pii/10.1038/s41598-022-24682-9; uri/info:pmid/36434137; uri/info:scp/85142476770; uri/info:pmcid/PMC9700709; https://dipot.ulb.ac.be/dspace/bitstream/2013/356139/1/doi_339783.pdf; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/356139

الاتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/356139
https://dipot.ulb.ac.be/dspace/bitstream/2013/356139/1/doi_339783.pdf

المؤلفون: Pasquereau, Sébastien, Galais, Mathilde, Bellefroid, Maxime, Pachón Angona, Irene, Morot-Bizot, Stéphanie, Ismaili, Lhassane, Van Lint, Carine, Herbein, Georges

المساهمون: IF@ULB program, Fonds De La Recherche Scientifique - FNRS, Conseil régional de Bourgogne-Franche-Comté, Université Libre de Bruxelles, Université de Franche-Comté

المصدر: Scientific Reports ; volume 12, issue 1 ; ISSN 2045-2322

الاتاحة: http://dx.doi.org/10.1038/s41598-022-24682-9
https://www.nature.com/articles/s41598-022-24682-9.pdf
https://www.nature.com/articles/s41598-022-24682-9

المؤلفون: Pachón-Angona, Irene, Bernard, Paul J., Simakov, Alexey, Maj, Maciej, Jozwiak, Krzysztof, Novotna, Anna, Lemke, Carina, Gütschow, Michael, Martin, Helene, Oset-Gasque, María-Jesús, Contelles, José-Marco, Ismaili, Lhassane

المصدر: Pharmaceutics; Jan2024, Vol. 16 Issue 1, p121, 14p

مصطلحات موضوعية: CALCIUM ions, CALCIUM channels, NUCLEAR factor E2 related factor, LIGANDS (Biochemistry), OXIDANT status, ANTIOXIDANTS

المؤلفون: Pachón-Angona, Irene, Refouvelet, Bernard, Andrýs, Rudolf, Martin, Helène, Luzet, Vincent, Iriepa, Isabel, Moraleda, Ignacio, Diez-Iriepa, Daniel, Oset-Gasque, María-Jesús, Marco-Contelles, José, Musilek, Kamil, Ismaili, Lhassane

المساهمون: Regional Council of Franche-Comté, ERDF/ESF project PharmaBrain, University of Hradec Kralove

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry ; volume 34, issue 1, page 479-489 ; ISSN 1475-6366 1475-6374

الاتاحة: http://dx.doi.org/10.1080/14756366.2018.1545766
https://tandfonline.com/doi/pdf/10.1080/14756366.2018.1545766
https://www.tandfonline.com/doi/pdf/10.1080/14756366.2018.1545766

المؤلفون: Grosjean, Sylvain, Pachón-Angona, Irene, Dawra, Michella, Refouvelet, Bernard, Ismaili, Lhassane

المساهمون: Regional Council of Bourgogne Franche Comté

المصدر: Future Medicinal Chemistry ; volume 14, issue 21, page 1583-1606 ; ISSN 1756-8919 1756-8927

الاتاحة: http://dx.doi.org/10.4155/fmc-2022-0170
https://www.tandfonline.com/doi/pdf/10.4155/fmc-2022-0170

المؤلفون: Pachón-Angona, Irene, Maj, Maciej, Wnorowski, Artur, Martin, Helene, Jóźwiak, Krzysztof, Ismaili, Lhassane

المساهمون: Laboratoires de neurosciences intégratives et cliniques (EA 481), Université Bourgogne Franche-Comté COMUE (UBFC)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté COMUE (UBFC)-Université Bourgogne Franche-Comté COMUE (UBFC)

المصدر: ISSN: 1756-8919 ; Future Medicinal Chemistry ; https://univ-fcomte.hal.science/hal-03654559 ; Future Medicinal Chemistry, 2021, 13 (20), pp.1717-1729. ⟨10.4155/fmc-2021-0176⟩.

مصطلحات موضوعية: [CHIM.THER]Chemical Sciences/Medicinal Chemistry, [CHIM.ORGA]Chemical Sciences/Organic chemistry

Relation: hal-03654559; https://univ-fcomte.hal.science/hal-03654559

الاتاحة: https://univ-fcomte.hal.science/hal-03654559
https://doi.org/10.4155/fmc-2021-0176

المؤلفون: Zribi, Lazhar, Pachòn-Angona, Irene, Bautista-Aguilera, Òscar, Diez-Iriepa, Daniel, Marco-Contelles, José, Ismaili, Lhassane, Iriepa, Isabel, Chabchoub, Fakher

المساهمون: Laboratoires de neurosciences intégratives et cliniques (EA 481), Université Bourgogne Franche-Comté COMUE (UBFC)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté COMUE (UBFC)-Université Bourgogne Franche-Comté COMUE (UBFC)

المصدر: ISSN: 1420-3049 ; Molecules ; https://univ-fcomte.hal.science/hal-03654594 ; Molecules, 2020, 25 (14), pp.3190. ⟨10.3390/molecules25143190⟩.

مصطلحات موضوعية: [CHIM.ORGA]Chemical Sciences/Organic chemistry, [CHIM.THER]Chemical Sciences/Medicinal Chemistry

Relation: hal-03654594; https://univ-fcomte.hal.science/hal-03654594; PUBMEDCENTRAL: PMC7397274

الاتاحة: https://univ-fcomte.hal.science/hal-03654594
https://doi.org/10.3390/molecules25143190

المؤلفون: Pachòn Angona, Irene, Daniel, Solene, Martin, Helene, Bonet, Alexandre, Wnorowski, Artur, Maj, Maciej, Jóźwiak, Krzysztof, Silva, Tiago Barros, Refouvelet, Bernard, Borges, Fernanda, Marco-Contelles, José, Ismaili, Lhassane

المساهمون: Laboratoires de neurosciences intégratives et cliniques (EA 481), Université Bourgogne Franche-Comté COMUE (UBFC)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté COMUE (UBFC)-Université Bourgogne Franche-Comté COMUE (UBFC)

المصدر: ISSN: 1420-3049 ; Molecules ; https://univ-fcomte.hal.science/hal-03654614 ; Molecules, 2020, 25 (6), pp.1329. ⟨10.3390/molecules25061329⟩.

مصطلحات موضوعية: [CHIM.ORGA]Chemical Sciences/Organic chemistry, [CHIM.THER]Chemical Sciences/Medicinal Chemistry

Relation: hal-03654614; https://univ-fcomte.hal.science/hal-03654614; PUBMEDCENTRAL: PMC7144121

الاتاحة: https://univ-fcomte.hal.science/hal-03654614
https://doi.org/10.3390/molecules25061329

المؤلفون: Pachón Angona, Irene, Martin, Helene, Daniel, Solene, Moraleda, Ignacio, Bonet, Alexandre, Wnorowski, Artur, Maj, Maciej, Jozwiak, Krzysztof, Iriepa, Isabel, Refouvelet, Bernard, Marco-Contelles, José, Ismaili, Lhassane

المساهمون: Laboratoires de neurosciences intégratives et cliniques (EA 481), Université Bourgogne Franche-Comté COMUE (UBFC)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté COMUE (UBFC)-Université Bourgogne Franche-Comté COMUE (UBFC)

المصدر: ISSN: 1661-6596.

مصطلحات موضوعية: [CHIM.ORGA]Chemical Sciences/Organic chemistry, [CHIM.THER]Chemical Sciences/Medicinal Chemistry

Relation: hal-03654589; https://univ-fcomte.hal.science/hal-03654589; PUBMEDCENTRAL: PMC7589057

الاتاحة: https://univ-fcomte.hal.science/hal-03654589
https://doi.org/10.3390/ijms21207652

المؤلفون: Pachón-Angona, Irene, Martin, Helène, Chhor, Stecy, Oset-Gasque, María-Jesús, Refouvelet, Bernard, Marco-Contelles, José, Ismaili, Lhassane

المساهمون: Laboratoires de neurosciences intégratives et cliniques (EA 481), Université Bourgogne Franche-Comté COMUE (UBFC)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté COMUE (UBFC)-Université Bourgogne Franche-Comté COMUE (UBFC)

المصدر: ISSN: 1756-8919 ; Future Medicinal Chemistry ; https://univ-fcomte.hal.science/hal-03654634 ; Future Medicinal Chemistry, 2019, 11 (24), pp.3097-3108. ⟨10.4155/fmc-2019-0191⟩.

مصطلحات موضوعية: [CHIM.ORGA]Chemical Sciences/Organic chemistry, [CHIM.THER]Chemical Sciences/Medicinal Chemistry

Relation: hal-03654634; https://univ-fcomte.hal.science/hal-03654634

الاتاحة: https://univ-fcomte.hal.science/hal-03654634
https://doi.org/10.4155/fmc-2019-0191

المؤلفون: Benchekroun, Mohamed, Pachón-Angona, Irene, Luzet, Vincent, Martin, Helene, Oset-Gasque, María-Jesús, Marco-Contelles, José, Ismaili, Lhassane

المساهمون: Laboratoires de neurosciences intégratives et cliniques (EA 481), Université Bourgogne Franche-Comté COMUE (UBFC)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté COMUE (UBFC)-Université Bourgogne Franche-Comté COMUE (UBFC)

المصدر: ISSN: 0045-2068.

مصطلحات موضوعية: [CHIM.ORGA]Chemical Sciences/Organic chemistry, [CHIM.THER]Chemical Sciences/Medicinal Chemistry

Relation: hal-03654657; https://univ-fcomte.hal.science/hal-03654657

الاتاحة: https://univ-fcomte.hal.science/hal-03654657
https://doi.org/10.1016/j.bioorg.2018.12.029

المؤلفون: Pachón-Angona, Irene, Maj, Maciej, Wnorowski, Artur, Martin, Helene, Jóźwiak, Krzysztof, Ismaili, Lhassane

المصدر: Future Medicinal Chemistry; Oct2021, Vol. 13 Issue 20, p1717-1729, 13p

المؤلفون: Pachón-Angona, Irène

المساهمون: Bourgogne Franche-Comté, Ismaïli, Lhassane, Oset-Gasque, María Jesús

المصدر: Theses.fr

مصطلحات موضوعية: Maladie d’Alzheimer, Réactions multicomposants, Composes multicibles, Ugi reaction, Hantzsch reaction, Alzheimer’s disease, Multicomponent reactions, Multi-Targeted directed ligands, edu, envir

Relation: 10670/1.b6mrfi; http://www.theses.fr/2019UBFCE015

الاتاحة: http://www.theses.fr/2019UBFCE015