المؤلفون: Yoshizawa, Takuya, Ali, Rustam, Jiou, Jenny, Fung, Ho Yee Joyce, Burke, Kathleen A, Kim, Seung Joong, Lin, Yuan, Peeples, William B, Saltzberg, Daniel, Soniat, Michael, Baumhardt, Jordan M, Oldenbourg, Rudolf, Sali, Andrej, Fawzi, Nicolas L, Rosen, Michael K, Chook, Yuh Min

المصدر: Cell. 173(3)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Active Transport, Cell Nucleus, Binding Sites, Frontotemporal Lobar Degeneration, Humans, Karyopherins, Light, Liquid-Liquid Extraction, Macromolecular Substances, Magnetic Resonance Spectroscopy, Mutation, Nephelometry and Turbidimetry, Nuclear Localization Signals, Protein Binding, Protein Domains, RNA, RNA-Binding Protein FUS, Scattering, Radiation, Temperature, beta Karyopherins, FUS, PY-NLS, RNA granule, amyotrophic lateral sclerosis, biomolecular condensate, intrinsically disordered protein, karyopherin-β2, liquid-liquid phase separation, low-complexity sequences, transportin-1, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/721888cp
https://escholarship.org/content/qt721888cp/qt721888cp.pdf

المؤلفون: Scekic-Zahirovic, Jelena, Sendscheid, Oliver, El Oussini, Hajer, Jambeau, Mélanie, Sun, Ying, Mersmann, Sina, Wagner, Marina, Dieterlé, Stéphane, Sinniger, Jérome, Dirrig-Grosch, Sylvie, Drenner, Kevin, Birling, Marie-Christine, Qiu, Jinsong, Zhou, Yu, Li, Hairi, Fu, Xiang-Dong, Rouaux, Caroline, Shelkovnikova, Tatyana, Witting, Anke, Ludolph, Albert C, Kiefer, Friedemann, Storkebaum, Erik, Lagier-Tourenne, Clotilde, Dupuis, Luc

المصدر: The EMBO Journal. 35(10)

مصطلحات موضوعية: Neurosciences, Brain Disorders, Genetics, Dementia, Neurodegenerative, Rare Diseases, Acquired Cognitive Impairment, ALS, 2.1 Biological and endogenous factors, Aetiology, Neurological, Animals, Brain, Cytoplasm, Mice, Inbred C57BL, Mice, Transgenic, Motor Neurons, Mutation, RNA-Binding Protein FUS, Spinal Cord, amyotrophic lateral sclerosis, frontotemporal dementia, FUS, motor neuron degeneration, PY-NLS, PY‐NLS, Biological Sciences, Information and Computing Sciences, Medical and Health Sciences, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/404994bx

المؤلفون: Woong Y Hwang, Valentyna Kostiuk, Delfina P González, C Patrick Lusk, Mustafa K Khokha

المصدر: eLife, Vol 11 (2022)

مصطلحات موضوعية: β-catenin, nuclear transport, transportin 1, PY-NLS, karyopherinβ2, Wnt signaling, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/70495; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/d933d1a8959a4002b249ff633eca47b2

المؤلفون: Fang, Yufeng, Jang, Hyo Sang, Watson, Gregory W., Wellappili, Dulani P., Tyler, Brett M.

مصطلحات موضوعية: oomycetes, Phytophthora sojae, nuclear localization, NLS, classical NLS, PY-NLS, nucleus labeling

وصف الملف: application/pdf

Relation: http://hdl.handle.net/10919/76697; https://doi.org/10.3389/fmicb.2017.00010

الاتاحة: http://hdl.handle.net/10919/76697
https://doi.org/10.3389/fmicb.2017.00010

المؤلفون: Prachee Avasthi, Shengping Huang, Larissa L. Dougherty

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Kinesins, hTERT-RPE, human telomerase reverse transcriptase-retinal pigment epithelial, DMSO, dimethyl sulfoxide, Biochemistry, hnRNP A1, heterogenous nuclear ribonucleoprotein A1, Plant Proteins, EGFP, enhanced GFP, DMEM, Dulbecco's modified Eagle's medium, RanGTP, Chemistry, Cilium, kinesin-2, MDCK, Madin–Darby canine kidney, ciliary targeting, Cell biology, KAP3, kinesin-associated protein 3, WB, Western blot, KIF3A/3B, kinesin family member 3A/3B, KAP3, Kinesin, TIRFM, total internal reflection fluorescence microscopy, Research Article, MBP, maltose-binding protein, Active Transport, Cell Nucleus, NPC, nuclear pore complex, Importin, IPZ, importazole, Cell Line, 03 medical and health sciences, Intraflagellar transport, Humans, KIF3A, IF, immunofluorescence, Cilia, Molecular Biology, Adaptor Proteins, Signal Transducing, Cell Nucleus, TAP, Tris-acetate-phosphate, 030102 biochemistry & molecular biology, Chlamydomonas, Cell Biology, nuclear import, ARM6–9, armadillo-repeat region 6–9, Cytoskeletal Proteins, 030104 developmental biology, ran GTP-Binding Protein, NLS, nuclear localization signal, Ran, PY–NLS, proline-tyrosine NLS, BSA, bovine serum albumin, Nuclear transport, Ciliary base, IFT, intraflagellar transport, HA, hemagglutinin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394f6c5893101db0828d1a48546d4f4f
https://pubmed.ncbi.nlm.nih.gov/33234597

المؤلفون: Daniel J. Saltzberg, Seung Joong Kim, William B. Peeples, Rustam Ali, Michael M. Soniat, Jenny Jiou, Yuan Lin, Andrej Sali, Nicolas L. Fawzi, Michael K. Rosen, Yuh Min Chook, Ho Yee Joyce Fung, Takuya Yoshizawa, Rudolf Oldenbourg, Jordan M. Baumhardt, Kathleen A. Burke

المصدر: Cell, vol 173, iss 3

مصطلحات موضوعية: 0301 basic medicine, RNA granule, low-complexity sequences, amyotrophic lateral sclerosis, Magnetic Resonance Spectroscopy, Light, Nuclear Localization Signals, Medical and Health Sciences, Scattering, 0302 clinical medicine, Scattering, Radiation, Radiation, Temperature, transportin-1, liquid-liquid phase separation, Biological Sciences, beta Karyopherins, Active Transport, Membrane, Transportin 1, Macromolecule, Protein Binding, karyopherin-β2, Macromolecular Substances, Liquid-Liquid Extraction, Active Transport, Cell Nucleus, Importin, Biology, Karyopherins, PY-NLS, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Stress granule, Protein Domains, Nephelometry and Turbidimetry, Humans, Cellular compartment, FUS, Cell Nucleus, Binding Sites, intrinsically disordered protein, 030104 developmental biology, Mutation, Biophysics, RNA-Binding Protein FUS, RNA, biomolecular condensate, Nuclear transport, Frontotemporal Lobar Degeneration, 030217 neurology & neurosurgery, Nuclear localization sequence, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a37b68163c846ed834bc6d8d66f139be
https://escholarship.org/uc/item/721888cp

المؤلفون: Kevin Drenner, Jérôme Sinniger, Mélanie Jambeau, Oliver Sendscheid, Anke Witting, Jelena Scekic-Zahirovic, Tatyana A. Shelkovnikova, Marie-Christine Birling, Albert C. Ludolph, Erik Storkebaum, Sina Mersmann, Caroline Rouaux, Clotilde Lagier-Tourenne, Marina Wagner, Stéphane Dieterlé, Luc Dupuis, Xiang-Dong Fu, Hajer El Oussini, Ying Sun, Hairi Li, Friedemann Kiefer, Yu Zhou, Jinsong Qiu, Sylvie Dirrig-Grosch

المساهمون: Mécanismes Centraux et Périphériques de la Neurodégénérescence, Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Max Planck Institute for Molecular Biomedicine, Max-Planck-Gesellschaft, University of California [San Diego] (UC San Diego), University of California, Institut Clinique de la Souris (ICS), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), School of Psychology [Cardiff University], Cardiff University, University of Ulm (UUlm), Ludwig Institute for Cancer Research, Dieterle, Stéphane, University of California (UC)

المصدر: The EMBO journal, vol 35, iss 10
EMBO Journal
EMBO Journal, EMBO Press, 2016, 35 (10), pp.1077-1097. ⟨10.15252/embj.201592559⟩
EMBO Journal, 2016, 35 (10), pp.1077-1097. ⟨10.15252/embj.201592559⟩

مصطلحات موضوعية: 0301 basic medicine, Cytoplasm, amyotrophic lateral sclerosis, PY‐NLS, motor neuron degeneration, [SDV]Life Sciences [q-bio], Mutant, Inbred C57BL, frontotemporal dementia, Medical and Health Sciences, Transgenic, MESH: Spinal Cord, MESH: Heart Conduction System, [SCCO]Cognitive science, Mice, 0302 clinical medicine, Gene expression, News & Views, MESH: Animals, MESH: Xenopus, Amyotrophic lateral sclerosis, Genetics, Motor Neurons, MESH: Middle Aged, MESH: RNA-Binding Protein FUS, General Neuroscience, Neurodegeneration, Brain, Biological Sciences, Cell biology, [SDV] Life Sciences [q-bio], medicine.anatomical_structure, Spinal Cord, MESH: HEK293 Cells, Knockout mouse, MESH: Nucleotide Motifs, MESH: Motor Neurons, MESH: Mutation, MESH: Myotonic Dystrophy, MESH: Mice, Transgenic, Mice, Transgenic, Biology, PY-NLS, General Biochemistry, Genetics and Molecular Biology, MESH: Sodium Channels, 03 medical and health sciences, MESH: Brain, MESH: Mice, Inbred C57BL, Information and Computing Sciences, medicine, Animals, Molecular Biology, Loss function, FUS, MESH: Humans, MESH: Molecular Sequence Data, General Immunology and Microbiology, MESH: Cytoplasm, MESH: NAV1.5 Voltage-Gated Sodium Channel, [SCCO] Cognitive science, Motor neuron, medicine.disease, MESH: Male, Mice, Inbred C57BL, 030104 developmental biology, MESH: RNA-Binding Proteins, Mutation, RC0321, RNA-Binding Protein FUS, MESH: Exons, MESH: Female, 030217 neurology & neurosurgery, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9046bc2ae20c3633cc4884e4d6ce8b79
https://escholarship.org/uc/item/404994bx

المؤلفون: Peter, St George-Hyslop, Julie Qiaojin, Lin, Akinori, Miyashita, Emma C, Phillips, Seema, Qamar, Suzanne J, Randle, GuoZhen, Wang

المصدر: Brain Research

مصطلحات موضوعية: PY-NLS, proline tyrosine nuclear localisation signal, PTM, post-translational modification, TNPO1, transportin 1/karyopherin β2, Biophysics, TAF15, TATA box binding protein 15, Phase separation, SMN, survival motor neuron, fALS, familial amyotrophic lateral sclerosis, Cytoplasmic Granules, Article, FUS, fused in sarcoma protein, Protein Domains, RRM, RNA recognition Motif, FTLD, frontotemporal lobar degeneration, Arginine methylation, Humans, QGSY, glutamine glycine serine and tyrosine repeats motif, DDX4, DEAD box helicase 4, RGG, arginine glycine glycine repeat motif, CHOP, C/EBP homologous protein gene, Cation-pi interactions, EWS, Ewing sarcoma protein, ComputingMethodologies_COMPUTERGRAPHICS, Amyotrophic Lateral Sclerosis, RNA-Binding Proteins, Neurodegenerative Diseases, Temporal Lobe, DNA-Binding Proteins, Frontotemporal Dementia, Mutation, hnRNP, heterogeneous nuclear ribonucleoprotein, RNA-Binding Protein FUS, ADMA FUS, asymmetrically di-methylated arginine FUS, TDP-43, transactive response DNA binding protein 43, RNA binding proteins, Frontotemporal Lobar Degeneration, Protein Processing, Post-Translational

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::d7c33cdb5ca19f9cf1f4a371dcd4e851
https://pubmed.ncbi.nlm.nih.gov/29723523

المؤلفون: Fang, Yufeng, Jang, Hyo Sang, Watson, Gregory W., Wellappili, Dulani P., Tyler, Brett M.

المصدر: Frontiers in Microbiology

مصطلحات موضوعية: Microbiology (medical), Phytophthora sojae, classical NLS, nucleus labeling, NLS, nuclear localization, PY-NLS, Microbiology, oomycetes, Original Research

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4c3a9aa1231dd452d87d498ca1e3216a
https://hdl.handle.net/10919/76697

المؤلفون: Son, Susie

Thesis Advisors: Truant, Ray, Biochemistry and Biomedical Sciences

مصطلحات موضوعية: Huntington's disease, huntingtin, HMGB1, neurodegeneration, nuclear localization, N17, PY-NLS, ROS, oxidative stress, phosphorylation

الاتاحة: http://hdl.handle.net/11375/22188

المؤلفون: Yuh Min Chook, Katherine E. Süel

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1813(9):1593-1606

مصطلحات موضوعية: Models, Molecular, Saccharomyces cerevisiae Proteins, Transportin, Nuclear import, Molecular Sequence Data, Nuclear Localization Signals, Active Transport, Cell Nucleus, NLS, macromolecular substances, Importin, Karyopherins, Biology, PY-NLS, Bioinformatics, Article, 03 medical and health sciences, Nuclear localization signal, 0302 clinical medicine, Humans, Protein Interaction Domains and Motifs, Amino Acid Sequence, Nuclear pore, Molecular Biology, 030304 developmental biology, Karyopherin, chemistry.chemical_classification, 0303 health sciences, Cell Biology, Classical-NLS, beta Karyopherins, Cell biology, Nuclear pore complex, Nuclear localization, chemistry, Transportin 1, Beta Karyopherins, Nuclear transport, 030217 neurology & neurosurgery, Nuclear localization sequence, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7ba41ec864d5d90a8f57e42994355a

المؤلفون: Mallet, Pierre-Luc

Thesis Advisors: Bachand, François

مصطلحات موضوعية: 'PY-NLS et CENP-B, Rétrotransposon, Karyophérine, Expression génique, Import nucléaire, poly(A)-binding protein, S. pombe'

الاتاحة: http://hdl.handle.net/11143/6660

المؤلفون: Banerjee, Silpi

مصطلحات موضوعية: 42.13 Molekularbiologie, Transportin 1 / Karyopherin-β2 / Kernlokalisationssignal / nukleozytoplasmatischen Verkehr / PY-NLS / Kernimport / NLS / RNA-bindende / RNA-Editing / ADAR / dsRBD / NMR, Transportin 1 / Karyopherin-β2 / nuclear localization signal / nucleocytoplasmic transport / PY-NLS / nuclear import / NLS / RNA-binding / RNA-editing / ADA / dsRBD / NMR

وصف الملف: pdf

Relation: Banerjee, Silpi (2014) Nuclear import by an ADAR1 double stranded RNA binding domain. Dissertation, Universität Wien. Zentrum für Molekulare Biologie BetreuerIn: Jantsch, Michael F.

الاتاحة: http://othes.univie.ac.at/32162/

المؤلفون: Dorothee Dormann

المصدر: Europe PubMed Central
The EMBO Journal

مصطلحات موضوعية: 0301 basic medicine, amyotrophic lateral sclerosis, PY‐NLS, motor neuron degeneration, Mutant, Biology, frontotemporal dementia, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, medicine, Humans, Molecular Biology of Disease, Motor Neuron Disease, Amyotrophic lateral sclerosis, Molecular Biology, FUS, Motor Neurons, Nerve degeneration, General Immunology and Microbiology, Mechanism (biology), General Neuroscience, Point mutation, Articles, Anatomy, medicine.disease, 030104 developmental biology, Nerve Degeneration, Motor neuron degeneration, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a39fdc6d980b1deebf07213af2e761c
http://europepmc.org/abstract/med/27053723

المؤلفون: Fang, Yufeng, Jang, Hyo Sang, Watson, Gregory W., Wellappili, Dulani P., Tyler, Brett M.

مصطلحات الفهرس: oomycetes, Phytophthora sojae, nuclear localization, NLS, classical NLS, PY-NLS, nucleus labeling, Article - Refereed

URL: http://hdl.handle.net/10919/76697