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المؤلفون: George Frimpong Boafo, Zhongjian Chen, Marwa Ahmed Sallam, Qingqing Xiao, Makhloufi Zoulikha, Wei He
المصدر: Acta Pharmaceutica Sinica. B
مصطلحات موضوعية: Small interfering RNA, ARDS, DOTAP, 1,2-dioleoyl-3-trimethylammonium-propane, IFN, interferons, Review, CS, cigarette smoke, TNF-α, tumor necrosis factor-α, MIF, macrophage migration inhibitory factor, AAV, adeno-associated virus, General Pharmacology, Toxicology and Pharmaceutics, AV, adenovirus, dsDNA, double-stranded DNA, DODAP, 1,2-dioleyl-3-dimethylammonium-propane, AM, alveolar macrophage, pDNA, plasmid DNA, PS, pulmonary surfactant, EpiC, epithelial cell, RNAi, RNA interference, Mrna level, HMGB1, high-mobility group box 1, NETs, neutrophil extracellular traps, SNALP, stable nucleic acid lipid particle, VILI, ventilator-induced lung injury, DODMA, 1,2-dioleyloxy-N,N-dimethyl-3-aminopropane, ALI/ARDS, PF, pulmonary fibrosis, HNPs, hybrid nanoparticles, PAMPs, pathogen-associated molecular patterns, DDAB, dimethyldioctadecylammonium bromide, TGF-β, transforming growth factor-β, DAMPs, danger-associated molecular patterns, HALI, hyperoxic acute lung injury, NPs, nanoparticles, PDGFRα, platelet-derived growth factor receptor-α, PEG, polyethylene glycol, PEI, polyethyleneimine, VALI, ventilator-associated lung injury, EC, endothelial cell, CPP, cell-penetrating peptide, ATII, alveolar cell type II, medicine.disease, PMs, polymeric micelles, DOPC, 1,2-dioleoyl-sn-glycero-3-phosphocholine, PD-L1, programmed death ligand-1, COPD, chronic obstructive pulmonary disease, HMVEC, human primary microvascular endothelial cell, siRNA, small interfering RNA, siRNA, ALI/ARDS, acute lung injury/acute respiratory distress syndrome, EPC, egg phosphatidylcholine, Nanoparticles, LPS, lipopolysaccharides, N/P ratio, nitrogen /phosphate ratio, Chemokine, PRR, pattern recognition receptor, EXOs, exosomes, DOPE, 1,2-dioleoyl-L-α-glycero-3-phosphatidylethanolamine, PEEP, positive end-expiratory pressure, ICAM-1, intercellular adhesion molecule-1, Inflammatory diseases, Hem-CLP, hemorrhagic shock followed by cecal ligation and puncture septic challenge, Bioinformatics, SLN, solid lipid nanoparticle, Cellular uptake, miRNA, microRNA, RISC, RNA-induced silencing complex, NF-κB, nuclear factor kappa B, PLGA, poly(D,L-lactic-co-glycolic acid), biology, FDA, US Food and Drug Administration, Ago-2, argonaute 2, DPPC, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine, PAMAM, polyamidoamine, Endosomal escape, mRNA, messenger RNA, medicine.anatomical_structure, PAI-1, plasminogen activator inhibitor-1, shRNA, short RNA, DC-Chol, 3β-(N-(N’,N’-dimethylethylenediamine)-carbamoyl) cholesterol, Drug delivery, DOSPA, 2,3-dioleyloxy-N-[2-(sperminecarboxamido)ethyl]-N,N-dimethyl-1-propanaminium, TLR, Toll-like receptor, PFC, perfluorocarbon, Acute respiratory distress, Lung injury, DPI, dry powder inhaler, eggPG, L-α-phosphatidylglycerol, ROS, reactive oxygen species, medicine, Pulmonary administration, DOTMA, N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium, Lung, business.industry, MEND, multifunctional envelope-type nano device, CFDA, China Food and Drug Administration, ATI, alveolar cell type I, RIP2, receptor-interacting protein 2, Myd88, myeloid differentiation primary response 88, biology.protein, dsRNA, double-stranded RNA, CXCR4, C-X-C motif chemokine receptor type 4, business, DOGS, dioctadecyl amido glycin spermine