المؤلفون: Bryce, Alan, Agarwal, Neeraj, Beltran, Himisha, Hussain, Maha, Sartor, Oliver, Shore, Neal, Antonarakis, Emmanuel, Armstrong, Andrew, Calais, Jeremie, Carducci, Michael, Dorff, Tanya, Efstathiou, Jason, Gleave, Martin, Gomella, Leonard, Higano, Celestia, Hope, Thomas, Iagaru, Andrei, Morgans, Alicia, Morris, David, Morris, Michael, Petrylak, Daniel, Reiter, Robert, Rettig, Matthew, Ryan, Charles, Sellinger, Scott, Spratt, Daniel, Srinivas, Sandy, Tagawa, Scott, Taplin, Mary-Ellen, Yu, Evan, Zhang, Tian, McKay, Rana, Koo, Phillip, Crawford, E

المصدر: Cancer. 131(1)

مصطلحات موضوعية: advanced prostate cancer, androgen receptor pathway inhibitors, biochemical recurrence, consensus recommendations, poly(ADP‐ribose) polymerase (PARP) inhibitors, radioligand therapy, Humans, Male, Prostatic Neoplasms, Neoplasm Recurrence, Local, Consensus, Evidence-Based Medicine, Prostate-Specific Antigen, Prostatic Neoplasms, Castration-Resistant, United States, Poly(ADP-ribose) Polymerase Inhibitors, Practice Guidelines as Topic

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1t44369g
https://escholarship.org/content/qt1t44369g/qt1t44369g.pdf

المؤلفون: Weiner, Adam B, Agrawal, Raag, Wang, Nicholas K, Sonni, Ida, Li, Eric V, Arbet, Jaron, Zhang, JJH, Proudfoot, James A, Hong, Boon Hao, Davicioni, Elai, Kane, Nathanael, Valle, Luca F, Kishan, Amar U, Dal Pra, Alan, Ghadjar, Pirus, Sweeney, Christopher J, Nickols, Nicholas G, Karnes, R Jeffrey, Shen, John, Rettig, Matthew B, Czernin, Johannes, Ross, Ashely E, Chua, Melvin Lee Kiang, Schaeffer, Edward M, Calais, Jeremie, Boutros, Paul C, Reiter, Robert E

المصدر: European Urology. 86(6)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Cancer, Genetics, Aging, Health Disparities, Biomedical Imaging, Minority Health, Prostate Cancer, Urologic Diseases, Radiation Oncology, Male, Humans, Prostatic Neoplasms, Glutamate Carboxypeptidase II, Antigens, Surface, Aged, Positron-Emission Tomography, Biomarkers, Tumor, Middle Aged, Prostatic neoplasms/genetics, Prostatic neoplasms/pathology, Gene expression, Biomarkers, Tumor, Prognosis, Gene expression profiling, Urology & Nephrology, Clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9bt5w5vj
https://escholarship.org/content/qt9bt5w5vj/qt9bt5w5vj.pdf

المؤلفون: Astellas Pharma Inc

المصدر: A Real-World Comparison of Clinical Outcomes in Chemotherapy-naive Metastatic Castration-resistant Prostate Cancer (mCRPC) Patients Who Initiated Enzalutamide vs. Abiraterone Acetate (Abiraterone) in Flatiron Electronic Health Record (EHR) Database

المصدر: A Phase 2, Randomized, Open-Label, Study of Lorigerlimab With Docetaxel or Docetaxel Alone in Participants With Metastatic Castration-Resistant Prostate Cancer

المصدر: A Phase 3 Randomized, Placebo-controlled, Double-blind Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone in Subjects With Metastatic Prostate Cancer

المؤلفون: Eli Lilly and Company

المصدر: Expanded Access Treatment with [Lu-177]-PNT2002 for Adult Patients with Prostate-Specific Membrane Antigen (PSMA)-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC)

المصدر: Drug-drug Interaction Study to Evaluate the Effect of Multiple Doses of JNJ-56021927 on the Pharmacokinetics of Multiple Cytochrome P450 and Transporter Substrates in Subjects With Castration-Resistant Prostate Cancer

المصدر: A Phase 1b-2 Study of Niraparib Combination Therapies for the Treatment of Metastatic Castration-Resistant Prostate Cancer

المصدر: Drug Use Investigation of Xofigo, Castration Resistant Prostate Cancer With Bone Metastases

المؤلفون: Flannery, Brennan, Sandler, Howard, Lal, Priti, Feldman, Michael, Santa-Rosario, Juan, Pathak, Tilak, Mirtti, Tuomas, Farre, Xavier, Correa, Rohann, Chafe, Susan, Shah, Amit, Efstathiou, Jason, Hoffman, Karen, Hallman, Mark, Straza, Michael, Jordan, Richard, Pugh, Stephanie, Feng, Felix, Madabhushi, Anant

المصدر: The Journal of pathology and bacteriology. 265(2)

مصطلحات موضوعية: biopsy, convolutional neural networks, deep learning, generalizability, interpretability, machine learning, morphology, prostate cancer, radical prostatectomy, Humans, Prostatic Neoplasms, Male, Deep Learning, Biopsy, Prostatectomy, Neural Networks, Computer

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6w53b300
https://escholarship.org/content/qt6w53b300/qt6w53b300.pdf

المؤلفون: Meher, Niranjan, Bidkar, Anil P, Wadhwa, Anju, Bobba, Kondapa Naidu, Dhrona, Suchi, Dasari, Chandrashekhar, Mu, Changhua, Fong, Cyril OY, Cámara, Juan A, Ali, Umama, Basak, Megha, Bulkley, David, Steri, Veronica, Fontaine, Shaun D, Zhu, Jun, Oskowitz, Adam, Aggarwal, Rahul R, Sriram, Renuka, Chou, Jonathan, Wilson, David M, Seo, Youngho, Santi, Daniel V, Ashley, Gary W, VanBrocklin, Henry F, Flavell, Robert R

المصدر: Molecular Cancer Therapeutics. 24(1)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Prostate Cancer, Urologic Diseases, Bioengineering, Cancer, Biotechnology, Nanotechnology, Biomedical Imaging, 5.1 Pharmaceuticals, Animals, Humans, Male, Mice, Zirconium, Positron-Emission Tomography, Prostatic Neoplasms, Radioisotopes, Nanoparticles, Polyethylene Glycols, Cell Line, Tumor, Drug Carriers, Xenograft Model Antitumor Assays, Permeability, Tissue Distribution, Pharmacology and Pharmaceutical Sciences, Oncology & Carcinogenesis, Biochemistry and cell biology, Oncology and carcinogenesis

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/15r591td
https://escholarship.org/content/qt15r591td/qt15r591td.pdf

المؤلفون: Orion Corporation, Orion Pharma

المصدر: MK-5684-01A Substudy: A Phase 1/2 Umbrella Substudy of MK-5684-U01 Master Protocol to Evaluate the Safety and Efficacy of MK-5684-based Treatment Combinations or MK-5684 Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC)

Other URLs: http://engagezone.msd.com/ds_documentation.php

المصدر: A Phase 1/1b First-in-Human, Open Label, Dose Escalation and Cohort Expansion Study of MGC026 in Participants With Advanced Solid Tumors

المؤلفون: Bayer

المصدر: Combination of Darolutamide and Stereotactic Body Radiation Therapy in Patients With Castration Resistant Prostate Cancer and Oligometastases on Functional Imaging

المؤلفون: Sagimet Biosciences Inc.

المصدر: A Phase I, Open-Label, Dose-Finding Study of TVB-2640 Administered in Combination With Enzalutamide (Xtandi) in Men With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

المؤلفون: German Cancer Research Center

المصدر: First in Human Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of the Bispecific PSMAxCD3 Antibody CC-1 in Patients with Castration Resistant Prostate Carcinoma
Lutz MS, Klimovich B, Maurer S, Heitmann JS, Marklin M, Zekri L, Jung G, Salih HR, Hinterleitner C. Platelets subvert antitumor efficacy of T cell-recruiting bispecific antibodies. J Immunother Cancer. 2022 Feb;10(2):e003655. doi: 10.1136/jitc-2021-003655.
Heitmann JS, Walz JS, Pflugler M, Kauer J, Schlenk RF, Jung G, Salih HR. Protocol of a prospective, multicentre phase I study to evaluate the safety, tolerability and preliminary efficacy of the bispecific PSMAxCD3 antibody CC-1 in patients with castration-resistant prostate carcinoma. BMJ Open. 2020 Oct 16;10(10):e039639. doi: 10.1136/bmjopen-2020-039639.

المؤلفون: Varuzhanyan, Grigor, Chen, Chia-Chun, Freeland, Jack, He, Tian, Tran, Wendy, Song, Kai, Wang, Liang, Cheng, Donghui, Xu, Shili, Dibernardo, Gabriella A, Esedebe, Favour N, Bhatia, Vipul, Han, Mingqi, Abt, Evan R, Park, Jung Wook, Memarzadeh, Sanaz, Shackelford, David B, Lee, John K, Graeber, Thomas G, Shirihai, Orian S, Witte, Owen N

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 121(49)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Biological Sciences, Prostate Cancer, Urologic Diseases, Cancer, Lung, Rare Diseases, Genetics, Lung Cancer, Humans, Basic Helix-Loop-Helix Transcription Factors, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Mitochondria, Male, Oxidative Phosphorylation, Animals, Cell Line, Tumor, Disease Progression, Mice, Prostatic Neoplasms, Gene Expression Regulation, Neoplastic, Neuroendocrine Tumors, Cell Proliferation, PGC-1a, ASCL1, oxidative phosphorylation, lung cancer, prostate cancer

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0m23b4t7
https://escholarship.org/content/qt0m23b4t7/qt0m23b4t7.pdf

المؤلفون: Jathal, Maitreyee K, Mudryj, Maria, Dall’Era, Marc A, Ghosh, Paramita M

المصدر: Cellular and Molecular Life Sciences. 82(1)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Cancer, Prostate Cancer, Aging, Urologic Diseases, 6.1 Pharmaceuticals, 5.1 Pharmaceuticals, Lapatinib, Humans, Receptor, ErbB-3, Male, Prostatic Neoplasms, Protein Kinase Inhibitors, Cell Line, Tumor, Amiloride, Receptor, ErbB-2, Cell Nucleus, Antineoplastic Agents, Cell Proliferation, Receptors, Androgen, Tyrosine Kinase Inhibitors, Receptor, erbB-2, Receptor, erbB-3, Androgen receptor, ErbB3, Heregulin-1β, Prostate cancer, Subcellular localization, Biochemistry and Cell Biology, Physiology, Biochemistry & Molecular Biology, Biochemistry and cell biology, Medical biochemistry and metabolomics, Oncology and carcinogenesis

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8403v9p9
https://escholarship.org/content/qt8403v9p9/qt8403v9p9.pdf

المؤلفون: Shen, Michelle, García-Marqués, Fernando, Muruganantham, Arvind, Liu, Shiqin, White, James, Bermudez, Abel, Rice, Meghan, Thompson, Kelsey, Chen, Chun-Liang, Hung, Chia-Nung, Zhang, Zhao, Huang, Tim, Liss, Michael, Pienta, Kenneth, Pitteri, Sharon, Stoyanova, Tanya

المصدر: British Journal of Cancer. 131(11)

مصطلحات موضوعية: Humans, Male, Prostatic Neoplasms, Disease Progression, Prognosis, Proteomics, Aged, Biomarkers, Tumor, Middle Aged, Neoplasm Metastasis, Gene Expression Profiling, Disease-Free Survival, Gene Expression Regulation, Neoplastic, Transcriptome, Neoplasm Recurrence, Local

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1291d5x7
https://escholarship.org/content/qt1291d5x7/qt1291d5x7.pdf

المؤلفون: Esfahani, Shadi, Morris, Michael, Sartor, Oliver, Frydenberg, Mark, Fanti, Stefano, Calais, Jeremie, Vapiwala, Neha

المصدر: European journal of nuclear medicine. 52(1)

مصطلحات موضوعية: Guideline, PET/CT, PSMA, Prostate cancer, Report, Positron Emission Tomography Computed Tomography, Humans, Glutamate Carboxypeptidase II, Male, Prostatic Neoplasms, Antigens, Surface, Reference Standards

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/57b486m0
https://escholarship.org/content/qt57b486m0/qt57b486m0.pdf