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1Academic Journal
المؤلفون: Rui Li, Chao Zhang, Fei Xie, Xianming Zhou, Xingjian Hu, Jiawei Shi, Xinling Du, Zhiyong Lin, Nianguo Dong
المصدر: Frontiers in Cardiovascular Medicine, Vol 8 (2022)
مصطلحات موضوعية: PP2A (protein phosphatase 2A), atherosclerosis, foam cell formation, p38, CD36, Diseases of the circulatory (Cardiovascular) system, RC666-701
وصف الملف: electronic resource
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2Academic Journal
المصدر: Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
مصطلحات موضوعية: PP2A (protein phosphatase 2A), B56-PP2A, LxxIxE SLiM, integrase, viral PP2A targeting, Microbiology, QR1-502
وصف الملف: electronic resource
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3
المؤلفون: Niani Tiaye Bailey, Bilon Khambu, Gang Liu, Sophia Blessinger, Katherine Byrnes, Russell Scaife
المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 33-49 (2022)مصطلحات موضوعية: MCOLN1, mucolipin 1, Review, OPTN, optineurin, UPR, unfolded protein response, LIMP1, lysosomal integral membrane protein-1, General Pharmacology, Toxicology and Pharmaceutics, BNIP3L, BCL2 interacting protein 3 like, STBD1, starch-binding domain-containing protein 1, PLIN3, perilipin 3, LIR, LC3 interacting region, PPARα, peroxisomal proliferator-activated receptor-alpha, mTORC1, mammalian target of rapamycin complex 1, Translation (biology), WIPI1, WD repeat domain phosphoinositide-interacting protein 1, TBK1, serine/threonine-protein kinase, Cell biology, GIM, GABARAP-interacting motif, CREB, cAMP response element binding protein, PP2A, protein phosphatase 2a, Liver metabolism, CLN3, lysosomal/endosomal transmembrane protein, LALP70, lysosomal apyrase-like protein of 70 kDa, LD, lipid droplet, RETREG1, reticulophagy regulator 1, PINK1, phosphatase and tensin homolog (PTEN)-induced kinase 1, RM1-950, ATL3, Atlastin GTPase 3, RTNL3, a long isoform of RTN3, LAMP2, lysosomal-associated membrane protein-2, FXR, farnesoid X receptor, Farnesoid X receptor, Cryptochrome 1, FFA, free fatty acid, TFEB/TFE3, transcription factor EB, ULK1, Unc-51 like autophagy activating kinase 1, TRAC-1, thyroid-hormone-and retinoic acid-receptor associated co-repressor 1, RTN3, reticulon 3, S6K, P70-S6 kinase, SEC62, SEC62 homolog, preprotein translocation factor, GABARAPL1, GABA type A receptor associated protein like 1, TEX264, testis expressed 264, ER-phagy receptor, DFCP1, double FYVE-containing protein 1, LXRa, liver X receptor a, SLC36A1, solute carrier family 36 member 1, V-ATPase, vacuolar-ATPase, Regeneration (biology), Quality control, AIM, Atf8 interacting motif, VLDL, very-low-density lipoprotein, CYP7A1, cholesterol 7α-hydroxylase, NBR1, BRCA1 gene 1 protein, BCL2L13, BCL2 like 13, TGR5, takeda G protein receptor 5, NCoR1, nuclear receptor co-repressor 1, PKA, protein kinase A, Function (biology), CRY1, cryptochrome 1, LAMP1, lysosomal-associated membrane protein-1, Anabolism, S6RP, S6 ribosomal protein, LIMP3, lysosomal integral membrane protein-3, FAM134B, family with sequence similarity 134, member B, Nutrient regeneration, SPIN, spindling, FOXO1, Forkhead box O1, SCARB2, scavenger receptor class B member 2, PQLC2, PQ-loop protein, SQSTM1, sequestosome 1, CMA, chaperonin mediated autophagy, PLIN2, perilipin 2, PXR, pregnane X receptor, NPC-1, Niemann-Pick disease, type C1, SLC38A9, sodium-coupled neutral amino acid transporter 9, Lysosome, TRPML1, transient receptor potential mucolipin 1, BNIP3, BCL2 interacting protein 3, BA, bile acid, ATM, ATM serine/threonine kinase, CAR, constitutive androstane receptor, MFSD1, major facilitator superfamily domain containing 1, NAFLD, non-alcoholic fatty liver disease, PKB, protein kinase B, VDR, vitamin D3 receptor, SIRT1, sirtuin 1, LYAAT-1, lysosomal amino acid transporter 1, SNAT7, sodium-coupled neutral amino acid transporter 7, Biology, S1PR2, sphingosine-1-phosphate receptor 2, ROS, reactive oxygen species, CYP27A1, sterol 27-hydroxylase, Autophagy, NDP52, calcium-binding and coiled-coil domain-containing protein 2, ATGL, adipose triglyceride lipase, Signaling proteins, Catabolism, FUNDC1, FUN14 domain containing 1, CCPG1, cell cycle progression 1, LAAT-1, lysosomal amino acid transporter 1 homologue, PEX5, peroxisomal biogenesis factor 5, PI3K, phosphatidylinositol-4,5-bisphosphate 3-kinase, SLC38A7, solute carrier family 38 member 7, Therapeutics. Pharmacology, Homeostasis, Drug metabolism
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4
المؤلفون: Ying Yan, Chitra Palanivel, Charles A. Enke, Geoffrey A. Talmon, Nichole D. Brandquist, Keith R. Johnson, Lepakshe S. V. Madduri, Michael J. Baine, Sumin Zhou, Michel M. Ouellette
المصدر: Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1192-1203 (2021)
Neoplasia (New York, N.Y.)مصطلحات موضوعية: p53, Cancer Research, FBXL20, F-Box and Leucine-Rich Repeat Protein 20, Ubiquitin, Dox, Doxycycline, PP2A, protein phosphatase 2A, Protein Phosphatase 2, siRNA, short interfering RNA, RC254-282, Original Research, Gene knockdown, DMEM, Dulbecco's modified Eagle's medium, FBXL20, biology, Protein Stability, Chemistry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, IP, immunoprecipitation, SCF, Skp1_Cullin1_F-box, Ubiquitin ligase, Cell biology, PP2A, c-Myc, shRNA, short hairpin RNA, Phosphorylation, IHC, immunohistochemistry, Signal Transduction, wt, wild-type, Protein subunit, Phosphatase, LATS, Large Tumor Suppressor Kinase, CHX, cycloheximide, KSR, Kinase Suppressor of Ras 1, Cell Line, Tumor, Skp1, Humans, IB, immunoblotting, PR55α, HPNE, human normal pancreatic cells, esiRNAs, endoribonuclease-prepared siRNAs, ATCC, American Type Culture Collection, F-Box Proteins, DMSO, Dimethyl sulfoxide, Protein phosphatase 2, RT-PCR, Reverse Transcription Polymerase Chain Reaction, YAP, Yes-associated protein, Pancreatic Neoplasms, biology.protein, Tumor Suppressor Protein p53, HPV16, human papillomavirus 16
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5
المؤلفون: Gregory Tiao, Talita Ferreira Margues Aguiar, Alexander Bondoc, Soona Shin, Maria Prates Rivas, Michael E. Johnston, Ruhi Gulati, Meenasri Kumbaji, Ana Cristina Victorino Krepischi, James I. Geller, Lubov Timchenko, Nikolai Timchenko
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1669-1682 (2021)مصطلحات موضوعية: Hepatoblastoma, SLC, solute carrier, HBL, hepatoblastoma, HDAC, histone deacetylase, RC799-869, MW, molecular weight, Epigenesis, Genetic, Enhancer binding, PP2A, protein phosphatase 2A, Original Research, OCT, organic cation transporter, Chemistry, Liver Neoplasms, Gastroenterology, Epigenetic, Cell Differentiation, Diseases of the digestive system. Gastroenterology, mRNA, messenger RNA, ChIP, chromatin immunoprecipitation, C/EBPα, medicine.anatomical_structure, Ola, Olaparib, Hepatocyte, embryonic structures, C/EBPα, CCAAT/Enhancer Binding Protein alpha, Liver cancer, Liver Cancer, animal structures, cdk2/4, cyclin dependent kinases 2 and 4, Sp5, Chromatin remodeling, medicine, Humans, PDX, patient-derived xenograft, Cell Proliferation, Hepatology, ALCD, aggressive liver cancer domain, Protein phosphatase 2, medicine.disease, NRF2, Nuclear factor erythroid-2, HDAC1, qRT-PCR, quantitative reverse-transcription polymerase chain reaction, enzymes and coenzymes (carbohydrates), PARP, Poly [ADP-ribose] polymerase, Cancer cell, Cancer research, SEC, size exclusion chromatography, HNF, Hepatocyte Nuclear Factor, Histone deacetylase, HCC, hepatocellular carcinoma, Co-IP, co-immunoprecipitation
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6
المؤلفون: Yueshui Zhao, Shengpeng Wang, Jun Pang, Bin Wei, Fukuan Du, Parham Jabbarzadeh Kaboli, Qinglian Wen, Xiaoxiao Wu, Mingxing Li, Xu Wu, Zhangang Xiao, Qijie Zhao, Meijuan Chen, Yitao Wang, Jing Li, Chi Hin Cho, Jing Shen
المصدر: Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1360-1381 (2020)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: hASC, human adipose stem cells, RB, retinoblastoma-associated protein, ESC, embryonic stem cell, PDAC, pancreatic ductal adenocarcinoma, Review, Genome, Regenerative medicine, ROCK, Rho kinase, hTERT, human telomerase reverse transcriptase, Y-27632, PP2A, protein phosphatase 2A, CYPs, cytochrome P450 enzymes, UVB, ultraviolet radiation b, General Pharmacology, Toxicology and Pharmaceutics, Drug discovery, LECs, limbal epithelial cells, ECM, extracellular matrix, CR, conditional reprogramming, Reprogramming, HCMI, human cancer model initiatives, dECM, decellularized extracellular matrix, NGFR, nerve growth factor receptor, ICD, intracellular domain, Computational biology, Biology, Senescence, NCI, National Cancer Institute, PDX, patient derived xenograft, NSCLC, non-small cell lung cancer, ROCK, NSG, NOD/SCID/gamma, SV40, simian virus 40 large tumor antigen, ΔNP63α, N-terminal truncated form of P63α, DCIS, ductal carcinoma in situ, iPSCs, induction of pluripotent stem cells, 3T3-J2 fibroblast, Mechanism (biology), ACC, adenoid cystic carcinoma, lcsh:RM1-950, Precision medicine, AACR, American Association for Cancer Research, lcsh:Therapeutics. Pharmacology, Cell culture, Conditional reprogramming, AR, androgen receptor, HGF, hepatocyte growth factor, HPV, human papillomaviruses, HNE, human nasal epithelial, Immortalised cell line, CFTR, cystic fibrosis transmembrane conductance regulators
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7Image
المؤلفون: Rui Li (4631), Chao Zhang (51048), Fei Xie (437662), Xianming Zhou (11957246), Xingjian Hu (11544985), Jiawei Shi (1658383), Xinling Du (9315974), Zhiyong Lin (3576542), Nianguo Dong (747605)
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8
المؤلفون: Rui Li (4631), Chao Zhang (51048), Fei Xie (437662), Xianming Zhou (11957246), Xingjian Hu (11544985), Jiawei Shi (1658383), Xinling Du (9315974), Zhiyong Lin (3576542), Nianguo Dong (747605)
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9
المؤلفون: Rui Li, Chao Zhang, Fei Xie, Xianming Zhou, Xingjian Hu, Jiawei Shi, Xinling Du, Zhiyong Lin, Nianguo Dong
مصطلحات موضوعية: Cardiology, Cardiology (incl. Cardiovascular Diseases), Cardiorespiratory Medicine and Haematology not elsewhere classified, PP2A (protein phosphatase 2A), atherosclerosis, foam cell formation, p38, CD36
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10Image
المؤلفون: Rui Li, Chao Zhang, Fei Xie, Xianming Zhou, Xingjian Hu, Jiawei Shi, Xinling Du, Zhiyong Lin, Nianguo Dong
مصطلحات موضوعية: Cardiology, Cardiology (incl. Cardiovascular Diseases), Cardiorespiratory Medicine and Haematology not elsewhere classified, PP2A (protein phosphatase 2A), atherosclerosis, foam cell formation, p38, CD36
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11
المؤلفون: Klaus Schughart, Diana Cabrera, Heike Kollmus, Carolin Pilzner, Sebastiaan M. Van Liempd, Juan M. Falcón-Pérez
المصدر: The Journal of biological chemistry
United States
The Journal of Biological Chemistryمصطلحات موضوعية: MCFA, medium-chain fatty acid, medicine.medical_treatment, Type 2 diabetes, ACC, acetyl-CoA carboxylase, medicine.disease_cause, Biochemistry, Mice, DC, dendritic cell, nPY, N1-methyl-n-pyridone-5-carboxamide, PP2A, protein phosphatase 2A, Influenza A virus, ACar, acylcarnitine, Beta oxidation, LPI, lysophosphatidylinositol, ACoA, acyl-CoA, diabetes, TMAO, trimethylamine N-oxide, Peroxisome, metabolomics, dpi, days postinfection, Gln, glutamine, Val, valine, LPC, (lyso)phosphatidylcholine, Phe, phenylalanine, Oxidation-Reduction, PAMP, pathogen-associated molecular pattern, Research Article, TLR, Toll-like receptor, LPE, lysophosphatidylethanolamine, TAG, triacylglycerol, mouse model, TCA, tricarboxylic acid, Biology, VLCFA, very long–chain fatty acid, beta-oxidation, Diabetes Mellitus, Experimental, 5HIU, 5-hydroxyisourate, NAM, nicotinamide, Orthomyxoviridae Infections, hrLCMS, high-resolution liquid chromatography–coupled mass spectrometry, Diabetes mellitus, Carnitine, IAV, influenza A virus, medicine, C5, complement component 5, MCar, malonylcarnitine, Animals, influenza A virus, ABCD, ATP-binding cassette D, Molecular Biology, LME, linear mixed-effect, Innate immune system, Ahr, aryl-hydrocarbon receptor, Insulin, Ile/Leu, isoleucine/leucine, FA, fatty acid, Cell Biology, Metabolism, MS, ACN, acetonitrile, medicine.disease, MNA, N1-methylnicotinamide, CPT, carnitine palmitoyltransferase, Diabetes Mellitus, Type 2, Immunology, LCFA, long-chain fatty acid, MCoA, malonyl-coenzyme A, Amino Acids, Branched-Chain, AcCoA, acetyl coenzyme A
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12
المؤلفون: Sneh Lata, Ritu Mishra, Ravi P. Arya, Pooja Arora, Anismrita Lahon, Akhil C. Banerjea, Vikas Sood
المصدر: Journal of Molecular Biology
مصطلحات موضوعية: DDX, DEAD-box RNA helicase, CDG1C, congenital disorder of N-linked glycosylation type 1C, CDGS, carbohydrate-deficient glycoprotein syndrome, RSV, Respiratory Syncytial Virus, CSNK2B, casein kinase 2 subunit beta, Review Article, VPS, vacuolar protein sorting, SREBP3, sterol regulatory element binding protein 3, Structural Biology, PP2A, protein phosphatase 2A, Clustered Regularly Interspaced Short Palindromic Repeats, ALG, Alpha-1,3-glucosyltransferase, TMPRSS2, transmembrane protease serine 2, HDACS, histone deacetylases, TLR, toll-like receptors, DENV, Dengue Virus, C1QTNF7, C1q and tumor necrosis factor-related protein 7, CIRV, Carnation Italian ringspot virus, VACV, vaccinia virus, HIV-1, Human Immunodeficiency Virus 1, LRRN2, leucine-rich repeat neuronal protein 2, HPV, Human Papilloma Virus, IAV, Influenza A virus, SBV, Schmallenberg virus, CRISPR, HSV-1, Herpes Simplex Virus-1, SNPs, single nucleotide polymorphisms, Host factors, EBV, Epstein–Barr virus, TMV, Tobacco Mosaic Virus, BCOR, BCL6 interacting co-repressor, COVID-19, coronavirus disease 19, CTRP, C1q complement/TNF-related protein, Host-Derived Cellular Factors, Viral diseases, ACE2, angiotensin-converting enzyme 2, VSV, Vesicular Somatitis Virus, CHIKV, Chikungunya Virus, HCV, Hepatitis C virus, Humans, COG, conserved oligomeric Golgi, RRA, robust-rank aggregation, Molecular Biology, Pandemics, ComputingMethodologies_COMPUTERGRAPHICS, Host Microbial Interactions, SARS-CoV-2, ARPP-19, cyclic adenosine monophosphate-regulated phosphoprotein 19, COVID-19, LIMA-1, LIM domain and actin binding-1, GDI2, GDP dissociation inhibitor beta, TBSV, Tomato bushy stunt virus, EPLIN, epithelial protein lost in neoplasm, HCC, hepatocellular carcinoma, SLC35B2, solute carrier family 35 member B2
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13
المؤلفون: Keira E. Mahoney, Jeffrey Shabanowitz, Donald F. Hunt
المصدر: Molecular & Cellular Proteomics : MCP
مصطلحات موضوعية: Phosphopeptides, p53, protein 53, CIP2A, cancerous inhibitor of phosphatase 2A, medicine.medical_treatment, coronavirus, Review, medicine.disease_cause, Biochemistry, Analytical Chemistry, PP2A, protein phosphatase 2A, Medicine, Protein Phosphatase 2, hepatitis HBV, 0303 health sciences, CagA, cytotoxin-associated antigen A, biology, 030302 biochemistry & molecular biology, Retinoblastoma protein, Neurodegenerative Diseases, PP2A, PP1, protein phosphatase 1, Virus Diseases, HCV, hepatitis C virus, Immunotherapy, hepatitis HCV, HPV, human papillomavirus, Major histocompatibility complex, AD, Alzheimer’s disease, SARS-CoV, severe acute respiratory syndrome associated coronavirus, 03 medical and health sciences, Memory T Cells, Immune system, Antigen, Special Issue: Immunopeptidomics, EBV, Epstein Barr virus, MHC class I, MHC, major histocompatibility complex, Humans, Molecular Biology, 030304 developmental biology, E2F, E2 family transcription factor, pRb, retinoblastoma protein, business.industry, Histocompatibility Antigens Class I, Cancer, medicine.disease, Epstein–Barr virus, HBV, hepatitis B virus, Immunology, biology.protein, business, HCC, hepatocellular carcinoma, papillomavirus HPV
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14
المؤلفون: Billy W. Newton, Michelle Trester-Zedlitz, Mark von Zastrow, Grace E. Peng, Nikoleta G. Tsvetanova, Jeffrey R. Johnson, Nevan J. Krogan, Andrew P. Kurland, David Jimenez-Morales
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Proteomics, Endosome, cAMP, cyclic AMP, PDE, phosphodiesterase, PDE, Biochemistry, SILAC, Second Messenger Systems, Receptors, G-Protein-Coupled, 03 medical and health sciences, GPCR, cAMP, PP2A, protein phosphatase 2A, Cyclic AMP, PKA, LC-MS/MS, Protein kinase A, Molecular Biology, SILAC, stable isotope labeling with amino acids in cell culture, G protein-coupled receptor, GPCR, G-protein-coupled receptor, 030102 biochemistry & molecular biology, Chemistry, Kinase, LC-MS/MS, liquid chromatography–tandem mass spectrometry, bPAC, Phosphoproteomics, phosphoproteomics, Fe3+-NTA IMAC, iron (III)-nitrilotriacetic acid immobilized metal ion affinity, Cell Biology, Protein phosphatase 2, Editors' Pick, bPAC, bacterial photoactivatable adenylyl cyclase, Cell biology, PP2A, 030104 developmental biology, Second messenger system, Phosphorylation, PKA, protein kinase A, Research Article, Signal Transduction
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15
المؤلفون: Jean-Marie Sontag, Goce Taleski, Diana Schuhmacher, Estelle Sontag, Henry Su
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, N2a, Neuro-2a, Proto-Oncogene Proteins c-fyn, OA, okadaic acid, Biochemistry, environment and public health, Amyloid beta-Protein Precursor, Mice, MβCD, methyl-β-cyclodextrin, Catalytic Domain, Neoplasms, PP2A, protein phosphatase 2A, Protein methylation, Amyloid precursor protein, Protein Phosphatase 2, Phosphorylation, biology, Chemistry, Leucine carboxyl methyltransferase 1, Brain, hemic and immune systems, 3-DZA, 3-deazaadenosine, Methylation, Alzheimer's disease, Cell biology, embryonic structures, AD, Alzheimer's disease, biological phenomena, cell phenomena, and immunity, signaling, Tyrosine kinase, Signal Transduction, Research Article, Cell signaling, neurite outgrowth, amyloid precursor protein (APP), HTL, Hcy thiolactone, SFKs, Src family kinases, pSFK, phosphorylated SFK, anti-HA, anti-hemagglutinin, 03 medical and health sciences, FYN, FBS, fetal bovine serum, Alzheimer Disease, APP, amyloid precursor protein, LCMT1, leucine carboxyl methyltransferase 1, Fyn, Neurites, Animals, Humans, protein methylation, Molecular Biology, EV, empty vector, 030102 biochemistry & molecular biology, protein phosphatase 2 (PP2A), tyrosine-protein kinase (tyrosine kinase), Cell Biology, Protein phosphatase 2, homocysteine, Hcy, homocysteine, PP2Ac, catalytic “C” subunit of PP2A, one-carbon metabolism, Aβ, amyloid-β, enzymes and coenzymes (carbohydrates), 030104 developmental biology, biology.protein, FD, folate-deficient, Holoenzymes, Protein Processing, Post-Translational, HA, hemagglutinin
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16
المؤلفون: Zarka Sarwar, Nusrat Nabi, Sameer Ahmed Bhat, Syed Qaaifah Gillani, Irfana Reshi, Misbah Un Nisa, Guillaume Adelmant, Jarrod A. Marto, Shaida Andrabi
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: LKB1, Carcinogenesis, Down-Regulation, Apoptosis, Cell Cycle Proteins, Nerve Tissue Proteins, OA, okadaic acid, KIAA 1967, Biochemistry, PARylation, poly ADP ribosylation, Sirtuin 1, PyST, polyoma small T antigen, PP2A, protein phosphatase 2A, Humans, Antigens, Viral, Tumor, tumor virus, Molecular Biology, Adaptor Proteins, Signal Transducing, mitosis, TAP, tandem affinity purification, pH3, phospho-histone 3, DBC1, CCAR2, AKT, Cell Biology, small T antigen, CCAR2, cell cycle and apoptosis regulator 2, DBC1, deleted in breast cancer 1, HSP, heat shock protein, tumor cell biology, Research Article
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17
المؤلفون: Andrew R. Clark, Michael Ohlmeyer
المصدر: Pharmacology & Therapeutics
مصطلحات موضوعية: 0301 basic medicine, PRR, pattern recognition receptor, IκBα, α inhibitor of NF-κB, IKK, IκBα kinase, AP-1, activator protein 1, law.invention, Serine, S1PR, S1P receptor, 0302 clinical medicine, DC, dendritic cell, law, Heterotrimeric G protein, Neoplasms, CCR4/NOT, carbon catabolite repressor 4/never on TATA-less, PP2A, protein phosphatase 2A, TGFβ, transforming growth factor β, Pharmacology (medical), TIRAP, Toll/interleukin 1 receptor domain-containing adaptor protein, Protein Phosphatase 2, Threonine, Phosphorylation, Protein phosphatase 2A, Cancer, chemistry.chemical_classification, UVB, ultraviolet B, TNF, tumor necrosis factor, TTP, tristetraprolin, Neurodegeneration, Neurodegenerative Diseases, SphK, sphingosine kinase, PAD, PP2A-activating drug, 3. Good health, Cell biology, TRIF, Toll/interleukin 1 receptor domain-containing adaptor inducing interferon β, 030220 oncology & carcinogenesis, JNK, cJun N-terminal kinase, LCMT-1, leucine carboxymethyl transferase 1, STRN, striatin, medicine.symptom, Alzheimer’s disease, PME-1, protein phosphatase methylesterase 1, PAMP, pathogen-associated molecular pattern, TAB, TAK1 binding protein, Signal Transduction, TLR, Toll-like receptor, BBB, blood-brain barrier, NF-κB, nuclear factor κ enhancer of activated B cells, Inflammation, MKK, MAPK kinase, macromolecular substances, AD, Alzheimer’s disease, CNS, central nervous system, Article, MS, multiple sclerosis, Multiple sclerosis, TAK1, transforming growth factor β-activated kinase, 03 medical and health sciences, ROS, reactive oxygen species, Drug Development, MyD88, myeloid differentiation factor 88, medicine, Animals, Humans, TRAF, TNF receptor interacting factor, MK2, MAPK-activated kinase 2, S1P, sphingosine-1-phosphate, Pharmacology, HEAT, Huntingtin - Elongation factor - A subunit of PP2A - Target of rapamycin domain, NFT, neurofibrillary tangles, Protein phosphatase 2, medicine.disease, IL, interleukin, 030104 developmental biology, Enzyme, chemistry, CIP2A, cancerous inhibitor of PP2A, Suppressor, LUBAC, linear ubiquitin chain assembly complex, TRAM, Toll/interleukin 1 receptor domain-containing adaptor molecule, IRF, interferon-regulatory factor, EAE, experimental autoimmune encephalopathy, MAPK, mitogen-activated protein kinase
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18
المؤلفون: Randal S. Tibbetts, Weiyan Jia, Sang Hwa Kim, Cheng-Guo Wu, Yongna Xing
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, BS1/2, B56 binding site 1/2, Serine 133, B56γ, Biochemistry, Mice, PP2A, protein phosphatase 2A, Cyclic AMP, PKA, Protein Phosphatase 2, Phosphorylation, KID, kinase-inducible domain, Cyclic AMP Response Element-Binding Protein, Cells, Cultured, SLiM, CLM, calicheamicin γ1, biology, CREB, Chemistry, PP2A, Cell biology, Histone, KIX domain, KID-interacting domain, Casein kinase 1, CK1/2, casein kinase 1/2, casein kinase, Fsk, Forskolin, SLiM, short linear motif, Protein Binding, Signal Transduction, Research Article, Transcriptional Activation, CRTCs, cAMP-regulated transcriptional coactivators, 03 medical and health sciences, cAMP, Animals, Humans, PMA, Phorbol 12-myristate 13-acetate, CREB-binding protein, Binding site, CBP, CREB-binding protein, Molecular Biology, Binding Sites, 030102 biochemistry & molecular biology, Cell Biology, Protein phosphatase 2, 030104 developmental biology, biology.protein, CREB, cAMP response element-binding protein, HeLa Cells
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19
المؤلفون: Dengke Tian, Liang Xin, Minge Wan, Xie Xiaolin, Zhang Dezhu, Wenqiang Cao, Liang Chengyuan, Liu Yuzhi, Li Han, Hong Liu, Xueqi Fu
المصدر: Biomedicine & Pharmacotherapy
Biomedicine & Pharmacotherapy, Vol 137, Iss, Pp 111313-(2021)مصطلحات موضوعية: 0301 basic medicine, Coronaviruses, medicine.medical_treatment, viruses, Review, Pharmacology, chemistry.chemical_compound, 0302 clinical medicine, nsps, Non-structural proteins, Chloroquine, Medicine, CoV, Coronavirus, CQ, Chloroquine, HA, Haemagglutinin, Molecular Targeted Therapy, Enzyme Inhibitors, DAAs, Direct-acting antiviral agents, biology, FDA, US Food and Drug Administration, Therapies, Investigational, HTAs, Host-targeting antivirals, MERS-CoV, Middle East respiratory syndrome coronavirus, General Medicine, Small molecule, PIP2, Phosphatidylinositol 4,5-bisphosphate, RMP, Ribavirin monophosphate, IFN, Interferon, N, Nucleocapsid protein, COVID-19, 2019 Coronavirus disease, HIV, Human immunodeficiency virus, RBV, Ribavirin, NIAID, National Institute of Allergy and Infectious Diseases, 030220 oncology & carcinogenesis, 6MP, 6-Mercaptopurine, BSAs, Broad-spectrum antiviral drugs, RDP, Ribavirin diphosphate, EBOV, Ebola virus, Transmembrane serine protease (TMPRSS2), GTP, Guanosine triphosphate, medicine.drug, 3CLpro, 3C-Like protease, DHODH, Dihydroorotate dehydrogenase, 6TG, 6-Thioguanine, Papain-like protease (PLpro), TGN, Trans-Golgi network, RM1-950, Favipiravir, TMPRSS2, HyCoSuL, Hybrid Combinatorial Substrate Library, Antiviral Agents, PP2A, Protein phosphatase 2A, SARS-CoV, Severe acute respiratory syndrome coronavirus, WHO, World Health Organization, CPE, Cytopathic effect, PLpro, Papain-like protease, 03 medical and health sciences, EUA, Emergency use authorization, IRF3, Interferon regulatory factor 3, SAR, Structure-activity relationship, ACE2, Angiotensin-converting enzyme 2, S, Spike protein, SKP2, S-Phase kinase-associated protein 2, Humans, RdRp, RNA-dependent RNA polymerase, RTP, Ribavirin triphosphate, BECN1, Beclin1, ComputingMethodologies_COMPUTERGRAPHICS, Serine protease, SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2, Protease, HC, QHydroxychloroquine, business.industry, SARS-CoV-2, Ribavirin, fungi, COVID-19, PC, Pro-protein convertase, DHO, Dihydroorotate, M, Membrane protein, RNA-dependent RNA polymerase (RdRp), COVID-19 Drug Treatment, AMPK, AMP-activated protein kinase, CMK, Decanoyl-RVKR-chloromethylketone, Mpro, Main protease, 030104 developmental biology, chemistry, 3C-like protease (3CLpro), E, Envelope protein, biology.protein, Dihydroorotate dehydrogenase, GM1, Monosialotetrahexosylganglioside 1, LPV/r, Lopinavir/ritonavir, Therapeutics. Pharmacology, ELs, Endolysosomes, business, IMPDH, Inosine monophosphate dehydrogenase
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20
المؤلفون: Ronald A. Merrill, Andrew Y. Usachev, Jianing Song, Stefan Strack
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Doublecortin Domain Proteins, 0301 basic medicine, proteasomal degradation, X-linked intellectual disability, PACAP, pituitary adenylate cyclase-activating polypeptide, CRL, cullin-RING ligase, dendritic complexity, MAP, microtubule-associated protein, Gene mutation, Biochemistry, pulse-chase, XLID, X-linked intellectual disability, AUC, area under the curve, ERK, extracellular signal-regulated kinase, Ubiquitin, PP2A, protein phosphatase 2A, Chlorocebus aethiops, GFP, green fluorescent protein, Neurons, biology, KLHL, Kelch-like, DCX, doublecortin, Microfilament Proteins, IP, immunoprecipitation, Editors' Pick, Ubiquitin ligase, Cell biology, E3 ubiquitin ligase, Cul3, cullin3, COS Cells, BDNF, brain-derived neurotrophic factor, doublecortin-like kinases, Microtubule-Associated Proteins, Research Article, neurite outgrowth, Doublecortin Protein, Ubiquitin-Protein Ligases, Blotting, Western, Protein degradation, ubiquitination, Gene product, 03 medical and health sciences, TMR, tetramethyl rhodamine, Intellectual Disability, GST, glutathione-S-transferase, medicine, Animals, Humans, Immunoprecipitation, Gene silencing, Molecular Biology, Trk, tropomyosin-related kinase, 030102 biochemistry & molecular biology, protein phosphatase 2A, protein turnover, Neuropeptides, DCLK, doublecortin-like kinase, Cell Biology, medicine.disease, microtubule-associated protein, Doublecortin, HEK293 Cells, 030104 developmental biology, Proteostasis, Proteasome, biology.protein
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