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المؤلفون: Daiichiro Fuchimoto, Minoru Kitago, Hisashi Aso, Yoshihisa Suyama, Akira Onishi, Osamu Itano, Ayumi Matsuo, Kanae Niimi, Yoshifumi Sakai, Yoji Sasahara, Tomonori Nochi, Fuller W. Bazer, Shotaro Morita, Sachiko Matsuda, Shunichi Suzuki, Katsuki Usami, Kouichi Watanabe, Shun Ito, Guoyao Wu, Mutsumi Furukawa
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 83-100 (2020)مصطلحات موضوعية: 0301 basic medicine, Male, Swine, Organogenesis, X-SCID, X-linked severe combined immunodeficiency, X-Linked Combined Immunodeficiency Diseases, NARO, National Agriculture and Food Research Organization, Animals, Genetically Modified, Gene Knockout Techniques, Peyer's Patches, 0302 clinical medicine, PCR, polymerase chain reaction, ILFs, isolated lymphoid follicles, Medicine, Intestinal Mucosa, Child, Original Research, GFP, green fluorescent protein, Bone Marrow Transplantation, PP, Peyer’s patch, Gastroenterology, ELISA, enzyme-linked immunosorbent assay, X-SCID, medicine.anatomical_structure, Treatment Outcome, Child, Preschool, RT, room temperature, 030211 gastroenterology & hepatology, Female, IgA, Interleukin Receptor Common gamma Subunit, Adult, Adolescent, Microflora, 03 medical and health sciences, Immune system, Animals, Humans, In vivo animal model, lcsh:RC799-869, Gene, Immunity, Mucosal, Feces, Severe combined immunodeficiency, PCA, principal component analysis, Hepatology, Peyer’s Patches, business.industry, BMT, medicine.disease, LTi, lymphoid tissue inducer, Ig, immunoglobulin, WT, wild-type, Small intestine, BMT, bone marrow transplantation, IL, interleukin, Gastrointestinal Microbiome, IVIG, intravenous immunoglobulin, Disease Models, Animal, 030104 developmental biology, Immunoglobulin G, Immunology, lcsh:Diseases of the digestive system. Gastroenterology, Immune disorder, business
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المؤلفون: Aimee G Kim, Melissa N. Orr, Robert O. Heuckeroth, Kendall M. Lawrence, Haiying Li, Heron D. Baumgarten, William H. Peranteau, Marcus G. Davey, Grace Hwang, Ali Y. Mejaddam, Lauren J. Brown, Christina M. Wright, Alan W. Flake, Barbara E. Coons, Zoya Butt, Patrick E. McGovern, Ronald C. Rubenstein, Avery C. Rossidis, Antoneta Radu
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 623-637 (2020)مصطلحات موضوعية: 0301 basic medicine, Pathology, Umbilical Cord, 0302 clinical medicine, Bowel Development, Intestinal Mucosa, Original Research, PP, Peyer’s patch, digestive, oral, and skin physiology, Gastroenterology, ICC, interstitial cells of Cajal, medicine.anatomical_structure, In utero, Necrotizing enterocolitis, EXTEND, EXTrauterine Environment for Neonatal Development, Premature Birth, Female, 030211 gastroenterology & hepatology, medicine.medical_specialty, Crypt, Ileum, Biology, 03 medical and health sciences, Extracorporeal Membrane Oxygenation, Fetus, Immune system, Fetal Organ Maturity, Enterocolitis, Necrotizing, Necrotizing Enterocolitis, medicine, Animals, Humans, lcsh:RC799-869, TTX, tetrodotoxin, IQR, interquartile range, EGF, epidermal growth factor, I-FABP, intestinal fatty-acid binding protein, NEC, necrotizing enterocolitis, ENS, enteric nervous system, Sheep, Hepatology, Infant, Newborn, medicine.disease, digestive system diseases, Epithelium, EGFR, epidermal growth factor receptor, Disease Models, Animal, 030104 developmental biology, Animals, Newborn, Fetal Lamb, Extreme Prematurity, lcsh:Diseases of the digestive system. Gastroenterology, Enteric nervous system
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المؤلفون: George, Joel Johnson, Oittinen, Mikko, Martin-Diaz, Laura, Zapilko, Veronika, Iqbal, Sharif, Rintakangas, Terhi, Arrojo Martins, Fábio Tadeu, Niskanen, Henri, Katajisto, Pekka, Kaikkonen, Minna U., Viiri, Keijo
المساهمون: Tampere University, BioMediTech, Tays Research Services, Clinical Medicine, Molecular and Integrative Biosciences Research Programme, Doctoral Programme in Integrative Life Science, Centre of Excellence in Stem Cell Metabolism, Doctoral Programme in Biomedicine
المصدر: Cellular and Molecular Gastroenterology and Hepatology
مصطلحات موضوعية: Esrrg, MECHANISM, GP2, glycoprotein 2 receptor, FAE, follicle-associated epithelium, Mice, Peyer's Patches, ENR500, epidermal growth factor, Noggin, R-spondin 500 ng/mL media, 3123 Gynaecology and paediatrics, INFECTION, Rank, receptor activator of nuclear factor κB, LTβR, lymphotoxin-β receptor, TRANSCRIPTION, RT-qPCR, reverse-transcription quantitative polymerase chain reaction, Intestinal Mucosa, WENRC media, Wnt, epidermal growth factor, Noggin, R-spondin, Chir media, Original Research, PP, Peyer’s patch, 318 Medical biotechnology, Receptor Activator of Nuclear Factor-kappa B, NF-kappa B, Polycomb Repressive Complex 2, Cell Differentiation, RankL, receptor activator of nuclear factor κB ligand, PRC2, DIFFERENTIATION, ERR, ChIP-seq, chromatin immunoprecipitation sequencing, Signal Transduction, EPITHELIAL M-CELLS, PBS, phosphate-buffered saline, INHIBITION, NF-κB, nuclear factor-κB, RankL, RELB, FACTOR SPI-B, Gro-seq, global run-on sequencing, Animals, HISTONE H3, KO, knockout, Microfold Cells, Gene Expression Profiling, Esrrg, estrogen-related receptor γ, RANK Ligand, Epithelial Cells, ENRI media, epidermal growth factor, Noggin, R-spondin, Wnt inhibitor IWP2 media, M cell, Microfold cell, GALT, gut-associated lymphoid tissue, Gene Expression Regulation, 3121 General medicine, internal medicine and other clinical medicine, 3111 Biomedicine, Gut Immunity, Biomarkers, PRC2, polycomb repressive complex 2
وصف الملف: fulltext
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المؤلفون: Rodney D. Newberry, Devesha H. Kulkarni
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 729-737 (2019)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: 0301 basic medicine, Macromolecular Substances, Treg, regulatory T cell, Review, Biology, Adaptive Immunity, 03 medical and health sciences, 0302 clinical medicine, Immune system, DC, dendritic cell, SI, small intestine, MLN, mesenteric lymph node, medicine, LP, lamina propria, Animals, Humans, Antigen Transport, Antigens, lcsh:RC799-869, Mucosal Tolerance, Epithelial barrier, Gastrointestinal tract, CX3CR1, C-X3-C Motif Chemokine Receptor 1, PP, Peyer's patch, Hepatology, Gastroenterology, Biological Transport, biochemical phenomena, metabolism, and nutrition, Acquired immune system, Intestinal epithelium, Epithelium, Cell biology, EGFR, epidermal growth factor receptor, IL, interleukin, Intestines, 030104 developmental biology, medicine.anatomical_structure, M cell, microfold cell, APC, antigen-presenting cell, Nutrient absorption, bacteria, 030211 gastroenterology & hepatology, GAP, goblet cell–associated antigen passage, lcsh:Diseases of the digestive system. Gastroenterology, Goblet Cells, TED, transepithelial dendrite, Foxp3+, forkhead box P3, TLR, Toll-like receptor
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المؤلفون: Mercedes Lopez-Santalla, Juan A. Bueren, Marina I. Garin
المصدر: EBioMedicine, Vol 69, Iss, Pp 103427-(2021)
EBioMedicineمصطلحات موضوعية: Oncology, ID, intradermal, RANTES, regulated upon activation normal T cells expressed and presumably secreted, AS, arthritis score, RA, rheumatoid arthritis, PPAR, peroxisome proliferator-activated receptor, Etanercept, TNF-α, tumour necrosis factor α, Bzb, bortezomib, iLNs, inguinal lymph nodes, CXCR3, chemokine receptor 3-alternative, BMZ, betamethasone, Medicine, CIA, collagen-induced arthritis, PP, peyer's patch, GIP, gastric inhibitory polypeptide, D, days, EVs, extracellular vesicles, Mtx, methotrexate, mAIA, antigen-induced arthritis in mouse, MTC, Masson´s trichrome, 030220 oncology & carcinogenesis, Rheumatoid arthritis, CTLA4, cytotoxic T lymphocyte antigen, iNOS, inducible nitric oxide synthase, KC, keratinocyte chemo-attractant, OCPs, osteoclast precursors, MCP-1, monocyte chemotactic protein 1, PTPN22, protein tyrosine-phosphatase 22, medicine.medical_specialty, rAIA, adjuvant-induced arthritis in rats, MensMSCs, MSCs from menstrual fluid, BM-MSCs, MSCs from bone marrow, MIP-2, macrophage inflammatory protein 2, 03 medical and health sciences, R5-920, IP10, IFN-γ-induced protein 10, IM, intramuscular, NRP-1, neuropilin-1, S, syngeneic, ESR, erythrocyte sedimentation rate, MPs, microparticles, PBMCs, peripheral blood mononuclear cells, AD, adipose tissue, MVs, microvesicles, P, placenta, sCIA, collagen-induced arthritis in sheep, Bregs, regulatory B cells, X, xenogeneic, Improvements in MSC-based therapy, AD-MSCs, MSCs from adipose tissue, 030104 developmental biology, TF, tissue factor, Protocols, Gilz, glucocorticoid-induced leucine zipper, DM, dexamethasone, STAT3, signal transducer and activator of transcription 3, ANA, Anti-nuclear antibodies, SAA, serum amyloid-A, ERDF, European Regional Development Fund, µCT, micro computed tomography imaging, Arthritis, Rheumatoid, T-AOC, total antioxidant capacity, rCIA, collagen-induced arthritis in rats, ISCT, international society for cellular therapy, NF-κB, nuclear factor-kappa B, RORγT, retinoic acid-related orphan receptor, TCR, T cell receptor, OVAIA, ovalbumin-induced arthritis, UC, umbilical cord, CAIA, collagen-antibody induced arthritis, Flk, tyrosine kinase receptor for vascular endothelial growth factor, IDO, indoleamine 2,3-dioxygenase, MMP, matrix metalloproteinase, Tr1, IL-10-expressing T cells, SM, synovial membrane, medicine.anatomical_structure, IAA, indoleacetic acid, MPCs, mesenchymal precursor cells, SNP, sodium nitroprusside, medicine.drug, NA, not available, IL-1RA, IL-1 receptor antagonist, CD, cluster of differentiation, DMARDs, antirheumatic drugs, TBO, toluidine blue O, =, similar to or equal, SM-MSCs, MSCs from synovial membrane, Mesenchymal Stem Cell Transplantation, PB, peripheral blood, G, gingiva tissue, IFA, incomplete Freund´s adjuvant, OVA, ovalbumin, MSCs, mesenchymal stem/ stromal cells, SO, safranin, TRAF, tumour necrosis factor receptor-associated factor, Animals, SP, spleen, ILA, indole-3-lactic acid, mBSA, methylated bovine serum albumin, business.industry, F, female, SF, synovial fluid, Th, T helper cells, TLR, toll-like receptors, BM, bone marrow, Bone marrow, Synovial membrane, MRI, magnetic resonance imaging, WT, wild type, Medicine (General), IHC, immunohistochemical analysis, Review, miR, microRNA, TRACP, tartrate-resistant acid phosphatase, AAV, adeno-associated virus, 0302 clinical medicine, GSH, glutathione, SVF, stromal vascular fraction, H/E, haematoxylin/eosin staining, GITR, glucocorticoid-induced tumour necrosis factor receptor, pLNs, popliteal lymph nodes, FOXP3, General Medicine, IFI, indirect immunofluorescence, Tregs, regulatory T cells, M, male, RF, rheumatoid factor, RNA, ribonucleic acid, TNFR, tumour necrosis factor receptor, <, worse than, IP, intraperitoneal, NuMa, nuclear mitotic apparatus, COMP, cartilage oligomeric matrix protein, GSH-Px, glutathione peroxidase, >, better than, LP, lamina propria, LPS, lipopolysaccharide, IN, intranodal, AT, antithrombin, General Biochemistry, Genetics and Molecular Biology, CM, conditioned medium, Consec., consecutive, RAGE, receptor for advanced glycation products, ETN, etanercept, Humans, dLNs, draining lymph nodes, MDA, malondialdehyde, IFN-γ, interferon gamma, ALP, alkaline phosphatase, HSCs, hematopoietic stem cells, Mesenchymal stem cell, Mesenchymal Stem Cells, medicine.disease, EMA, European medicine agency, IL, interleukin, CFA, Freund's complete adjuvant, DAB, 3,3´-diaminobenzidine, OPG, osteoprotegerin, HMGB-1, high-mobility group box-1, CRP, C reactive protein, Tol-DCs, tolerogenic dendritic cells, 0301 basic medicine, CII, collagen II, SF-MSCs, MSCs from synovial fluid, MPO, myeloperoxidease, A, allogeneic, LDL, low density lipoprotein, APCP, α, β methylene selective A2A adenosine receptor competitive antagonist (CD73 inhibitor), Translational Research, Biomedical, SSEA, severe spontaneous erosive arthritis, mLNs, mesenteric lymph nodes, PGIA, proteoglycan-induced arthritis, Exos, small vesicles/Exosomes, FOXP3, forkhead box P3, RANKL, receptor activator of nuclear factor κB ligand, TGF-β, transforming growth factor β, Stromal vascular fraction, NSAIDs, non-steroidal anti-inflammatory drugs, VEGF, vascular endothelial growth factor, Animal models, AhR, aryl hydrocarbon receptor, DCs, dendritic cells, IV, intravenous, Stromal cell, IA, intra-articular, SIRT1, sirtuin 1, O-MSCs, MSCs from nasal tissue, PA, peri-articular, Tfh, follicular T helper cells, AxLNs, axillar lymph nodes, NK, natural killer cells, T-MSCs, MSCs from tonsil tissue, SOD, superoxide dismutase, Internal medicine, MHC, major histocompatibility complex, GLP-1, glucagon-like peptide 1, G-MSCs, MSCs from gingiva tissue, Mesenchymal stem/stromal cells, PG, proteoglycan, HLA-II, human leukocyte antigen-II, PLGA, poly-lactic-co-glycolic acid, HDL, high density lipoprotein, Ig, immunoglobulin, SC, subcutaneous, P-MSCs, MSCs from placenta tissue, POM-1, sodium polyoxotungstate (CD39 inhibitor), UC-MSCs, MSCs from umbilical cord, business, sIL6R, soluble IL-6 receptor
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المؤلفون: Ferrand, Audrey, Al Nabhani, Ziad, Sola Tapias, Nùria, Mas, Emmanuel, Hugot, Jean-Pierre, Barreau, Frederick
المساهمون: Institut de Recherche en Santé Digestive (IRSD ), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre de recherche sur l'Inflammation (CRI (UMR_S_1149 / ERL_8252 / U1149)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), CHU Toulouse, Hôpital des Enfants, Unité de Gastroentérologie, Hépatologie et Nutrition, Département de Pédiatrie, Hôpital Purpan [Toulouse], CHU Toulouse [Toulouse]-CHU Toulouse [Toulouse], Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris Diderot - Paris 7 (UPD7), CRI UMR 1149, Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), AP-HP Hôpital universitaire Robert-Debré [Paris], Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Service Gastroentérologie, hépatologie nutrition, diabétologie et maladies héréditaires du métabolisme pédiatrique [CHU Toulouse], Pôle Enfants [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Ferrand, Audrey
المصدر: Cellular and Molecular Gastroenterology and Hepatology 2 (7), 357-369. (2019)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Philadelphia, PA : American Gastroenterological Association, [2015]-, 2019, 7 (2), pp.357-369. ⟨10.1016/j.jcmgh.2018.10.009⟩
Cellular and Molecular Gastroenterology and Hepatology, 2019, 7 (2), pp.357-369. ⟨10.1016/j.jcmgh.2018.10.009⟩مصطلحات موضوعية: Carcinogenesis, NOD2, nucleotide-binding oligomerization domain 2, TNBS, trinitrobenzene sulfonic acid, [SDV]Life Sciences [q-bio], Nod2 Signaling Adaptor Protein, NF-κB, nuclear factor-κB, Review, Epithelial cells, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, MDP, muramyl dipeptide, Models, Biological, Nod2, Cancer, Colitis, Gut, HD, human defensin, CD, Crohn’s disease, [SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO], Animals, Humans, IFN, interferon, AMP, antimicrobial peptide, MLCK, myosin light-chain kinase, IRF4, interferon regulatory factor 4, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, Physiologie, Inflammation, PP, Peyer’s patch, TNF, tumor necrosis factor, KO, knockout, Muc, mucin, WT, wild-type, mRNA, messenger RNA, digestive system diseases, [SDV] Life Sciences [q-bio], Intestines, CEC, colonic epithelial cells, CARD, caspase activation and recruitment domain, CRC, colorectal cancer, physiology, MAPK, mitogen-activated protein kinase, TLR, Toll-like receptor
وصف الملف: application/pdf
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المؤلفون: Cambrian Y. Liu
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 3, Pp 543-544 (2020)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: Integrin beta Chains, Computer science, ITGB, Integrin subunit beta, Treg, regulatory T cell, MAdCAM-1, mucosal addressin cell adhesion molecule-1, computer.software_genre, T-Lymphocytes, Regulatory, Th, helper T cell, Regulatory T Cells, PCR, polymerase chain reaction, MLN, mesenteric lymph node, CD, Crohn’s disease, Code (cryptography), Humans, Integrin β7 Blockade, Gut-Associated Lymphoid Tissue, DSS, dextran sodium sulfate, SP, spleen, lcsh:RC799-869, Tconv, conventional T cells, TGF, transforming growth factor, Original Research, GFP, green fluorescent protein, Inflammation, PP, Peyer’s patch, IBD, inflammatory bowel disease, Hepatology, Programming language, Inflammatory Bowel Disease, Gastroenterology, CFSE, carboxyfluorescein succinimidyl ester, WT, wild-type, Gastrointestinal Microbiome, GALT, gut-associated lymphoid tissue, IL, interleukin, UC, ulcerative colitis, PLN, peripheral lymph node, lcsh:Diseases of the digestive system. Gastroenterology, computer
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المؤلفون: Britni M. Arlian, Norihito Kawasaki, Matthew S. Macauley, Nadezhda Gicheva, James C. Paulson
المصدر: Biochemical and Biophysical Research Communications
مصطلحات موضوعية: 0301 basic medicine, Antibody Affinity, Biochemistry, Peyer's Patches, 0302 clinical medicine, Cricetinae, Intestinal Mucosa, Peyer's patch, Microfold cell, Mice, Knockout, Mice, Inbred BALB C, PP, Peyer's patch, UEA-I, Ulex europaeus agglutinin-I, Antibodies, Monoclonal, respiratory system, Flow Cytometry, Immunohistochemistry, 3. Good health, medicine.anatomical_structure, M cell, Antibody, Protein Binding, medicine.drug_class, Biophysics, Antigens, Differentiation, Myelomonocytic, CHO Cells, Biology, Monoclonal antibody, Article, Siglec, sialic acid-binding immunoglobulin-like lectin, 03 medical and health sciences, Immune system, Cricetulus, Antigen, medicine, Oral vaccine, Animals, Humans, Molecular Biology, Sialic Acid Binding Immunoglobulin-like Lectins, Cell Membrane, SIGLEC, Cell Biology, Molecular biology, Small intestine, Mice, Inbred C57BL, 030104 developmental biology, HEK293 Cells, M cell, microfold cell, Siglec, Rats, Inbred Lew, Immunology, biology.protein, Biomarkers, 030215 immunology
وصف الملف: application/pdf