المؤلفون: Jeong Min Lee^1,2, Won Hyeok Lee^1,2, Seung Hyeon Cho^1,2, Jeong Woo Park^1,2, Hyuk Nam Kwon^1,2, Ji Hye Kim³, Sang Hun Lee^2,4, Ji Hyung Yoon^2,5, Sungchan Park^2,5, Seong Cheol Kim^2,5 0734955@uuh.ulsan.kr

المصدر: Investigative & Clinical Urology. Jan2025, Vol. 66 Issue 1, p56-66. 15p.

مصطلحات موضوعية: *POLY(ADP-ribose) polymerase, *G proteins, *CELL cycle, *DOCETAXEL, *DNA repair

المؤلفون: Pae, Sookhee¹ (AUTHOR), Sedukhina, Anna S.^1,2 (AUTHOR), Sugiyama, Runa³ (AUTHOR), Atanacio, Sarah J.² (AUTHOR), Ohara, Tatsuru⁴ (AUTHOR), Ishii, Masato⁴ (AUTHOR), Minagawa, Kimino⁵ (AUTHOR), Akichjev, Romaan^2,6 (AUTHOR), Go, Fumie^2,7 (AUTHOR), Chandankeri, Zayan^2,7 (AUTHOR), Janjetic, Zoran M. M.^2,7 (AUTHOR), Sato, Eri² (AUTHOR), Yamaura, Ayako² (AUTHOR), Meguro, Rei^2,8 (AUTHOR), Palanisamy, Kishore^2,9 (AUTHOR), Maeda, Ichiro^10,11 (AUTHOR), Takeuchi, Osamu¹² (AUTHOR), Suzuki, Nao⁴ (AUTHOR), Yudo, Kazuo¹ (AUTHOR), Bernal, Juan A.¹³ (AUTHOR)

المصدر: Scientific Reports. 12/28/2024, Vol. 14 Issue 1, p1-11. 11p.

مصطلحات موضوعية: *HOMOLOGOUS recombination, *POLY(ADP-ribose) polymerase, *MEDICAL sciences, *GENETIC overexpression, *OVARIAN cancer

المؤلفون: Langelier, Marie-France¹ (AUTHOR), Mirhasan, Manija¹ (AUTHOR), Gilbert, Karine² (AUTHOR), Sverzhinksy, Aleksandr¹ (AUTHOR), Furtos, Alexandra² (AUTHOR), Pascal, John M.¹ (AUTHOR) john.pascal@umontreal.ca

المصدر: Molecular Cell. Dec2024, Vol. 84 Issue 24, p4758-47477. 42720p.

مصطلحات موضوعية: *POLY(ADP-ribose) polymerase, *CATALYTIC activity, *POLY ADP ribose, *ENZYMES, *CYTOLOGY, *NICOTINAMIDE, *NAD (Coenzyme)

المؤلفون: Srkalovic, Gordan^1,2 (AUTHOR), Rothe, Michael³ (AUTHOR), Mangat, Pam K.³ (AUTHOR) TAPURPublications@asco.org, Garrett-Mayer, Elizabeth³ (AUTHOR), Ahn, Eugene R.⁴ (AUTHOR), Brouse, Gregory⁵ (AUTHOR), Chan, John⁶ (AUTHOR), Mehmi, Inderjit⁷ (AUTHOR), Khalil, Maya⁸ (AUTHOR), Duvivier, Herbert L.⁹ (AUTHOR), Gaba, Anu¹⁰ (AUTHOR), Leuva, Harshraj¹¹ (AUTHOR), Thota, Ramya¹² (AUTHOR), Yost, Kathleen J.¹³ (AUTHOR), Grantham, Gina N.³ (AUTHOR), Gregory, Abigail³ (AUTHOR), Hinshaw, Dominique C.³ (AUTHOR), Halabi, Susan¹⁴ (AUTHOR), Schilsky, Richard L.³ (AUTHOR)

المصدر: JCO Precision Oncology. 12/1/2024, Vol. 8, p1-13. 13p.

مصطلحات موضوعية: *POLY(ADP-ribose) polymerase, *EPIDERMAL growth factor receptors, *CANCER patients, *METASTATIC breast cancer, *DRUG labeling

المؤلفون: Tsang, Erica S.¹ (AUTHOR), Dhawan, Mallika S.¹ (AUTHOR), Pacaud, Romain¹ (AUTHOR), Thomas, Scott¹ (AUTHOR), Grabowsky, Jennifer¹ (AUTHOR), Wilch, Lauren¹ (AUTHOR), Karipineni, Silpa¹ (AUTHOR), Kelley, Robin Kate¹ (AUTHOR), Ko, Andrew H.¹ (AUTHOR), Collisson, Eric¹ (AUTHOR), Chapman, Jocelyn S.¹ (AUTHOR), Ueda, Stefanie¹ (AUTHOR), Bergsland, Emily K.¹ (AUTHOR), Munster, Pamela¹ (AUTHOR) Pamela.Munster@ucsf.edu

المصدر: JCO Precision Oncology. 12/1/2024, Vol. 8, p1-12. 12p.

مصطلحات موضوعية: *POLY(ADP-ribose) polymerase, *HOMOLOGOUS recombination, *DNA topoisomerase I, *PERITONEAL cancer, *IRINOTECAN

المؤلفون: Vuong, Billy¹ (AUTHOR), Fang, Yuhua¹ (AUTHOR), Tranmer, Geoffrey K.¹ (AUTHOR) Geoffrey.Tranmer@umanitoba.ca

المصدر: Canadian Journal of Chemistry. 2024, Vol. 102 Issue 12, p865-874. 10p.

مصطلحات موضوعية: *DRUG discovery, *POLY(ADP-ribose) polymerase, *SMALL molecules, *DNA repair, *DNA damage, *POLY ADP ribose, *CD38 antigen

المؤلفون: Bryce, Alan, Agarwal, Neeraj, Beltran, Himisha, Hussain, Maha, Sartor, Oliver, Shore, Neal, Antonarakis, Emmanuel, Armstrong, Andrew, Calais, Jeremie, Carducci, Michael, Dorff, Tanya, Efstathiou, Jason, Gleave, Martin, Gomella, Leonard, Higano, Celestia, Hope, Thomas, Iagaru, Andrei, Morgans, Alicia, Morris, David, Morris, Michael, Petrylak, Daniel, Reiter, Robert, Rettig, Matthew, Ryan, Charles, Sellinger, Scott, Spratt, Daniel, Srinivas, Sandy, Tagawa, Scott, Taplin, Mary-Ellen, Yu, Evan, Zhang, Tian, McKay, Rana, Koo, Phillip, Crawford, E

المصدر: Cancer. 131(1)

مصطلحات موضوعية: advanced prostate cancer, androgen receptor pathway inhibitors, biochemical recurrence, consensus recommendations, poly(ADP‐ribose) polymerase (PARP) inhibitors, radioligand therapy, Humans, Male, Prostatic Neoplasms, Neoplasm Recurrence, Local, Consensus, Evidence-Based Medicine, Prostate-Specific Antigen, Prostatic Neoplasms, Castration-Resistant, United States, Poly(ADP-ribose) Polymerase Inhibitors, Practice Guidelines as Topic

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1t44369g
https://escholarship.org/content/qt1t44369g/qt1t44369g.pdf

المؤلفون: Pacaud, Romain, Thomas, Scott, Chaudhuri, Sibapriya, Lazar, Ann, Timmerman, Luika A, Munster, Pamela N

المصدر: Breast Cancer Research. 27(1)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Breast Cancer, Cancer, Women's Health, Genetics, Orphan Drug, Rare Diseases, 5.1 Pharmaceuticals, 6.1 Pharmaceuticals, Poly(ADP-ribose) Polymerase Inhibitors, Humans, Animals, Recombinational DNA Repair, Female, Cell Line, Tumor, Mice, BRCA1 Protein, Xenograft Model Antitumor Assays, BRCA2 Protein, Drug Synergism, DNA Damage, Cell Proliferation, Enzyme Inhibitors, Triple Negative Breast Neoplasms, BRCA1, BRCA2, PARP inhibitor, DNMT inhibitor, Talazoparib, Decitabine, PARP1, DNMT1, Oncology & Carcinogenesis, Oncology and carcinogenesis

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/09w791x1
https://escholarship.org/content/qt09w791x1/qt09w791x1.pdf

المؤلفون: Carmichael, Juliet^1,2, Figueiredo, Ines¹, Gurel, Bora¹, Beije, Nick^1,2, Wei Yuan¹, Rekowski, Jan¹, Seed, George¹, Carreira, Suzanne¹, Bertan, Claudia¹, Fenor de La Maza, Maria de Los Dolores^1,2, Chandran, Khobe^1,2, Neeb, Antje¹, Welti, Jon¹, Gallagher, Lewis¹, Bogdan, Denisa¹, Crespo, Mateus¹, Riisnaes, Ruth¹, Ferreira, Ana¹, Miranda, Susana¹, Jinqiu Lu³

المصدر: Journal of Clinical Investigation. 11/1/2024, Vol. 134 Issue 21, p1-12. 12p.

مصطلحات موضوعية: *PROSTATE cancer, *POLY(ADP-ribose) polymerase, *CASTRATION-resistant prostate cancer, *HOMOLOGOUS recombination, *PROSTATE cancer patients, *CANCER patients

المؤلفون: Gulyaeva, Lyudmila^1,2 (AUTHOR) lfgulyaeva@gmail.com

المصدر: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 20, p11275. 4p.

مصطلحات موضوعية: *MACROPHAGE migration inhibitory factor, *POLY(ADP-ribose) polymerase, *PATHOLOGY, *TRIPLE-negative breast cancer, *BREAST cancer, *DNA mismatch repair, *POLY ADP ribose, *BREAST

المؤلفون: Ghorai, Atanu^1,2 (AUTHOR), Saha, Soumajit¹ (AUTHOR), Rao, Basuthkar J.^1,3 (AUTHOR) bjrao@uohyd.ac.in

المصدر: Genes & Environment. 9/18/2024, Vol. 46 Issue 1, p1-12. 12p.

مصطلحات موضوعية: *NUCLEAR proteins, *POLY(ADP-ribose) polymerase, *NUCLEOLIN, *MITOCHONDRIAL proteins, *PRECANCEROUS conditions, *ADP-ribosylation, *HOMEOSTASIS

المؤلفون: Ouararhni, Khalid¹ (AUTHOR), Mietton, Flore² (AUTHOR), Sabir, Jamal S. M.^3,4 (AUTHOR), Ibrahim, Abdulkhaleg^1,5 (AUTHOR), Molla, Annie² (AUTHOR), Albheyri, Raed S.^3,4 (AUTHOR), Zari, Ali T.^3,4 (AUTHOR), Bahieldin, Ahmed^3,4 (AUTHOR), Menoni, Hervé² (AUTHOR), Bronner, Christian¹ (AUTHOR), Dimitrov, Stefan^2,6 (AUTHOR) stefan.dimitrov@univ-grenoble-alpes.fr, Hamiche, Ali¹ (AUTHOR) hamiche@igbmc.fr

المصدر: BMC Biology. 9/2/2024, Vol. 22 Issue 1, p1-14. 14p.

مصطلحات موضوعية: *POLY(ADP-ribose) polymerase, *DNA damage, *ALKYLATING agents, *GENETIC transcription regulation, *CELL survival, *DNA repair, *CHROMATIN

المؤلفون: Shram, Stanislav I.¹ (AUTHOR) shram.img@yandex.ru, Shcherbakova, Tatyana A.² (AUTHOR), Abramova, Tatyana V.³ (AUTHOR), Smirnovskaya, Maria S.⁴ (AUTHOR), Balandina, Anastasia I.^1,5 (AUTHOR), Kulikov, Andrey V.⁶ (AUTHOR), Švedas, Vytas K.^2,7 (AUTHOR), Silnikov, Vladimir N.³ (AUTHOR), Myasoedov, Nikolay F.¹ (AUTHOR), Nilov, Dmitry K.² (AUTHOR)

المصدر: Biochemistry (00062979). Sep2024, Vol. 89 Issue 9, p1619-1630. 12p.

مصطلحات موضوعية: *POLY(ADP-ribose) polymerase, *METHYLGUANINE, *HIGH throughput screening (Drug development), *CHEMICAL synthesis, *MOLECULAR docking, *POLY ADP ribose

المصدر: APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

Other URLs: https://grants.nih.gov/policy/sharing.htm

المؤلفون: NRG Oncology

المصدر: A Randomized Trial of Selumetinib and Olaparib or Selumetinib Alone in Patients With Recurrent or Persistent RAS Pathway Mutant Ovarian and Endometrial Cancers: A ComboMATCH Treatment Trial

Other URLs: https://grants.nih.gov/policy/sharing.htm

المصدر: A Phase 2 Study of Olaparib and Cediranib for the Treatment of Recurrent Ovarian Cancer

المؤلفون: National Cancer Institute (NCI)

المصدر: EFFORT: Efficacy of AZD1775 in Parp Resistance; A Randomized 2-Arm, Non-Comparative Phase 2 Study of AZD1775 Alone or AZD1775 and Olaparib in Women With Ovarian Cancer Who Have Progressed During PARP Inhibition

المصدر: Biomarker Directed Trial of Temozolomide and PARP Inhibition in Relapsed SCLC

المصدر: Randomized Phase II Clinical Trial of Olaparib + Pembrolizumab vs. Olaparib Alone as Maintenance Therapy in Metastatic Pancreatic Cancer Patients With Germline BRCA1 or BRCA2 Mutations

Other URLs: https://grants.nih.gov/policy/sharing.htm

المؤلفون: NRG Oncology

المصدر: A Randomized Phase II Study Comparing Single-Agent Olaparib, Single Agent Cediranib, and the Combinations of Cediranib/Olaparib, Olaparib/Durvalumab (MEDI4736), Cediranib/Durvalumab (MEDI4736), Olaparib/AZD5363 (Capivasertib) in Women With Recurrent, Persistent or Metastatic Endometrial Cancer.: A Platform Trial for Women With Recurrent or Persistent Endometrial Cancer