المؤلفون: Chujie Chen, Jinyan He, Weixian Huang, Dong Xu, Zhaohui Li, Anqi Yang

المصدر: Scientific Reports, Vol 15, Iss 1, Pp 1-16 (2025)

مصطلحات موضوعية: Oxidative stress, Leydig cells, Transcriptome sequencing, PLK3, Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/92d9bb244e1c4a0487bc69f4770ed5dd

المؤلفون: Caiyue Ren, Tong Chen, Shishuo Zhang, Qingxia Gao, Jiahui Zou, Peng Li, Biaoxiong Wang, Yaxin Zhao, Aotian OuYang, Sizhu Suolang, Hongbo Zhou

المصدر: Emerging Microbes and Infections, Vol 12, Iss 2 (2023)

مصطلحات موضوعية: Swine influenza virus, PLK3, nucleoprotein, phosphorylation, virus replication, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2222-1751

URL الوصول: https://doaj.org/article/06c0767b7e36450fa5f34caaf1c51b60

المؤلفون: Jeyeon Lee, Jin Ook Chung, Seon-Young Park, Naveen Rajamohan, Aparna Singh, JungJin Kim, Val J. Lowe, SeungBaek Lee

المصدر: Biochemistry and Biophysics Reports, Vol 30, Iss , Pp 101247- (2022)

مصطلحات موضوعية: Diabetes, Pancreatic β-cells, Reactive oxygen species (ROS), Natural COA water, Plk3, Apoptosis, Biology (General), QH301-705.5, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405580822000474; https://doaj.org/toc/2405-5808

URL الوصول: https://doaj.org/article/8ae3d5a77cd3476fac841f2aa9ef723a

المؤلفون: Baochi Ou, Hongze Sun, Jingkun Zhao, Zhuoqing Xu, Yuan Liu, Hao Feng, Zhihai Peng

المصدر: Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-12 (2019)

مصطلحات موضوعية: Colorectal cancer, PLK3, Glucose metabolism, HSP90, STAT3, HK2, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13046-019-1418-2; https://doaj.org/toc/1756-9966

URL الوصول: https://doaj.org/article/44ad5b9058ae450b84b2b423d78bbd8d

المؤلفون: Sabine Gajewski, Andrea Hartwig

المصدر: Chemical Research in Toxicology. 33:1933-1940

مصطلحات موضوعية: DNA damage, Poly (ADP-Ribose) Polymerase-1, Ataxia Telangiectasia Mutated Proteins, 010501 environmental sciences, Toxicology, 01 natural sciences, PLK3, 03 medical and health sciences, PARP1, Cell Line, Tumor, Radiation, Ionizing, Gene expression, Humans, Gene, 030304 developmental biology, 0105 earth and related environmental sciences, 0303 health sciences, Cell growth, Chemistry, Cas9, General Medicine, Cell biology, Cell culture, Tumor Suppressor Protein p53, Transcriptome, DNA Damage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397e93f515b2b931226d4d64555319f3
https://doi.org/10.1021/acs.chemrestox.0c00130

المؤلفون: Javad Haddadnia, Chérif F. Matta, Cyrus Ahmadi Toussi

المصدر: Molecular Diversity. 25:899-909

مصطلحات موضوعية: Drug, 010405 organic chemistry, Kinase, Computer science, media_common.quotation_subject, Organic Chemistry, Biological activity, General Medicine, Computational biology, 010402 general chemistry, Elastic network, 01 natural sciences, Catalysis, 0104 chemical sciences, PLK3, Inorganic Chemistry, Serine, Drug Discovery, Physical and Theoretical Chemistry, Protein kinase A, Molecular Biology, Elastic network models, Information Systems, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6e34683ae30d2eeab48bf0ba20552ee6
https://doi.org/10.1007/s11030-020-10074-6

المؤلفون: Zhao-Qian Liu, Dan Li, Xi Li, Jun-Luan Mo, Han Yan, Yi Chen, Feng-Mei Pang, Longbo Zhang, Jun Wu, Hong-Hao Zhou

المصدر: Future Oncology. 16:367-382

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, DNA Repair, PLK3, 03 medical and health sciences, 0302 clinical medicine, Glioma, Biomarkers, Tumor, medicine, Humans, Gene, Alleles, Survival analysis, Neoplasm Staging, Proportional Hazards Models, biology, business.industry, Gene Expression Profiling, Cancer, General Medicine, DNA Methylation, Gene signature, Prognosis, medicine.disease, Gene Expression Regulation, Neoplastic, body regions, Wee1, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Mutation, DNA methylation, Cancer research, biology.protein, Female, Neoplasm Grading, business, DNA Damage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3acf589a037312b2cb75250ec43acf
https://doi.org/10.2217/fon-2019-0764

المؤلفون: M. Salvi, E. Trashi, G. Cozza, A. Negro, P.I. Hanson, L.A. Pinna

المصدر: BioTechniques, Vol 53, Iss 1, Pp 1-5 (2012)

مصطلحات موضوعية: acidophilic kinase, CK2, PLK2, PLK3, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/0736-6205; https://doaj.org/toc/1940-9818

URL الوصول: https://doaj.org/article/30a678584b814665add58f2fd54c277c

المؤلفون: Fragoso, Rita, Barata, João T.

مصطلحات موضوعية: C-terminal tail, C2 domain, CK2, GSK3, Kinases, PLK3, PTEN, Phosphorylation, Posttranslational modification, Src

Relation: info:eu-repo/grantAgreement/FCT/3599-PPCDT/113202/PT; info:eu-repo/grantAgreement/FCT/3599-PPCDT/122428/PT; https://www.sciencedirect.com/journal/methods; Methods. 2015 May;77-78:75-81; http://hdl.handle.net/10451/51652

الاتاحة: http://hdl.handle.net/10451/51652
https://doi.org/10.1016/j.ymeth.2014.10.015

المؤلفون: Edmond Fleischer, Vincent Kam Wai Wong, Thorsten Berg, Sara Abdelfatah, Thomas Efferth, Anette Klinger, Li Jun Yang, Qi Huang, Sami Hamdoun, Henry Johannes Greten, Angela Berg

المصدر: Acta Pharmaceutica Sinica B, Vol 9, Iss 5, Pp 1021-1034 (2019)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: PBD, Polo box domain, MTD, maximal tolerance dose, CDC25, cell division cycle 25, HIF-1α, hypoxia-inducible factor 1 α, MST, microscale thermophoresis, IC50, 50% inhibition concentration, MFP, M phase promoting factor, PARP-1, poly(ADP-ribose) polymerase-1, 0302 clinical medicine, FOXO, forkhead box O, Nec-1, necrostatin 1, CDC2, cell division cycle protein 2 homolog, General Pharmacology, Toxicology and Pharmaceutics, Mitotic catastrophe, CDK, cyclin-dependent kinase, 0303 health sciences, Chemistry, Polo-like kinase, Mono-targeted therapy, Cell cycle, BUBR1, budding uninhibited by benzimidazole-related 1, Polo box domain, 030220 oncology & carcinogenesis, PLK1, Polo-like kinase, Necroptosis, Spindle damage, PLK1, IHC, immunohistochemistry, Original article, APC/C, anaphase-promoting complex/cyclosome, PLK3, ABC, avidin-biotin complex, PI, propidium iodide, 03 medical and health sciences, FBS, fetal bovine serum, PDB, Protein Data Bank, Kd, the dissociation constant, Kinase activity, 030304 developmental biology, Akt/PKB signaling pathway, Cell growth, lcsh:RM1-950, LC3, light chain 3, lcsh:Therapeutics. Pharmacology, Cancer research, DAPKs, death-associated protein kinase, 3-MA, 3-methyladenine, DAPI, 4′,6-diamidino-2-phenylindole, SAC, spindle assembly checkpoint

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ace647c8e4c5307f8c6cf16d50546d6
http://www.sciencedirect.com/science/article/pii/S221138351830827X

المؤلفون: Vincent Kam Wai Wong, Anette Klinger, Sara Abdelfatah, Thomas Efferth, Edmond Fleischer

المصدر: Investigational New Drugs. 38:1-9

مصطلحات موضوعية: 0301 basic medicine, Leukemia, T-Cell, Population, Apoptosis, Cell Cycle Proteins, Polo-like kinase, Protein Serine-Threonine Kinases, PLK1, Chemical library, PLK3, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Proto-Oncogene Proteins, Tumor Cells, Cultured, Humans, Pharmacology (medical), Cytotoxicity, education, Protein Kinase Inhibitors, Cell Proliferation, Pharmacology, Biological Products, education.field_of_study, Chemistry, Kinase, Cell Cycle, Cell cycle, High-Throughput Screening Assays, Molecular Docking Simulation, 030104 developmental biology, Oncology, Biochemistry, 030220 oncology & carcinogenesis, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::393e66beaf59aef9b0aebb14104a2a20
https://doi.org/10.1007/s10637-019-00752-0

المؤلفون: Shilpa Singh, Brad Windle, Sumitra Deb, Elizabeth A. Fry, Jolene J. Windle, W. Andrew Yeudall, Kazushi Inoue, Swati Palit Deb, Catherine A. Vaughan, Steven R. Grossman, Mark A. Subler, Raghavendra Pillappa

المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)

مصطلحات موضوعية: 0301 basic medicine, Transcriptional Activation, Lung Neoplasms, Carcinogenesis, Science, Mutant, General Physics and Astronomy, Mice, Transgenic, Oncogenicity, Protein Serine-Threonine Kinases, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Article, PLK3, Serine, 03 medical and health sciences, Transactivation, Gene Knockout Techniques, Mice, 0302 clinical medicine, Protein Domains, Cell Line, Tumor, Spheroids, Cellular, medicine, Animals, Humans, Gene Knock-In Techniques, Phosphorylation, Tumour-suppressor proteins, Lung, Mutation, Multidisciplinary, Chemistry, Tumor Suppressor Proteins, General Chemistry, Cell biology, Disease Models, Animal, 030104 developmental biology, Mechanisms of disease, 030220 oncology & carcinogenesis, Gain of Function Mutation, Female, Lung cancer, Tumor Suppressor Protein p53

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3001552fe338f8bbf14360dc3fb8e02d
http://europepmc.org/articles/PMC7846773

المؤلفون: Celeste N. Alverez, Kiran S. Toti, Jung-Eun Park, Yangliu Xia, Kenneth A. Jacobson, Jeong K. Bang, Frank J. Gonzalez, Kyung S. Lee, Ganesha Rai, Kristopher W. Krausz

المصدر: J Med Chem

مصطلحات موضوعية: Male, Protein domain, Cell Cycle Proteins, Polo-like kinase, Protein Serine-Threonine Kinases, 01 natural sciences, PLK1, Article, PLK3, 03 medical and health sciences, Mice, Structure-Activity Relationship, Protein Domains, Neoplasms, Proto-Oncogene Proteins, Drug Discovery, Structure–activity relationship, Animals, Humans, Tissue Distribution, Protein Kinase Inhibitors, 030304 developmental biology, Cell Proliferation, 0303 health sciences, Kinase, Drug discovery, Chemistry, Prodrug, 0104 chemical sciences, Mice, Inbred C57BL, 010404 medicinal & biomolecular chemistry, Biochemistry, Molecular Medicine, HeLa Cells, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c1bc7f364b2b95856a5b65d3e79aa74
https://pubmed.ncbi.nlm.nih.gov/33175530

المؤلفون: Patrick von Morgen, Cecilia Aquino Perez, Matous Palek, Libor Macurek, Lenka Stolarova

المصدر: Cells, Vol 9, Iss 1506, p 1506 (2020)
Cells
Volume 9
Issue 6

مصطلحات موضوعية: DNA damage, Kinase, Chemistry, Tumor Suppressor Proteins, Phosphatase, protein phosphatase, protein kinase, General Medicine, Protein Serine-Threonine Kinases, Polo-like kinase 3, PLK1, Article, Cell Line, PLK3, Cell biology, stress, lcsh:Biology (General), Phosphoprotein Phosphatases, Humans, Phosphorylation, Kinase activity, Protein kinase A, lcsh:QH301-705.5

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d363e0ea73ca3de57c56abde55167510
https://www.mdpi.com/2073-4409/9/6/1506

المؤلفون: Shoumin Bai, Zhenghui Guo, Xianju Chen, Shengmeng Peng, Tao Du, Hai Huang, Yiming Lai, Chunhao Lin, Wanhua Wu, Xiaoming Ma

المصدر: Cancer Management and Research. 11:1517-1524

مصطلحات موضوعية: 0301 basic medicine, Kinase, Cell migration, Polo-like kinase, Biology, medicine.disease, Metastasis Gene, PLK3, Metastasis, 03 medical and health sciences, Prostate cancer, 030104 developmental biology, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, Cancer research, medicine, Gene

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4275696064257bfdb1ee1ff5d52f5bc4
https://doi.org/10.2147/cmar.s176762

المؤلفون: Xu Dazhong, Wang Qi, Jiang Yongping, Zhang Yanxi, Vega-SaenzdeMiera Eleazar, Osman Iman, Dai Wei

المصدر: Experimental Hematology & Oncology, Vol 1, Iss 1, p 5 (2012)

مصطلحات موضوعية: Plk3, Tumor angiogenesis, Tumor suppression, HIF-1α, PTEN, Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Relation: http://www.ehoonline.org/content/1/1/5; https://doaj.org/toc/2162-3619; https://doaj.org/article/ed4a743eab55469892f311635a0beec3

الاتاحة: https://doi.org/10.1186/2162-3619-1-5
https://doaj.org/article/ed4a743eab55469892f311635a0beec3

المؤلفون: Beate Köberle, Bettina Maria Strauch, Valery G. Golubev, Andrea Hartwig, Sabine Gajewski, Vasily D. Sen, Sarah Schoch

المصدر: Biochemical Pharmacology. 156:109-119

مصطلحات موضوعية: 0301 basic medicine, Cell Survival, Antineoplastic Agents, Apoptosis, Biochemistry, PLK3, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, medicine, Humans, Cytotoxicity, Carcinoma, Renal Cell, Pharmacology, Cisplatin, Bladder cancer, Molecular Structure, Chemistry, Cell Cycle, Cell cycle, medicine.disease, Gene Expression Regulation, Neoplastic, 030104 developmental biology, GCLC, Urinary Bladder Neoplasms, Cell culture, 030220 oncology & carcinogenesis, Cancer research, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f15462e46c5632a29e45d47888336c
https://doi.org/10.1016/j.bcp.2018.08.025

المؤلفون: Bin Di, Li-Li Xu, Fang Yan, Miao-miao Niu, Tong-yuan Lin, Cheng Jiang, Hong-ping Min

المصدر: Bioorganic & Medicinal Chemistry. 26:3429-3437

مصطلحات موضوعية: Phosphopeptides, 0301 basic medicine, Cell Membrane Permeability, Clinical Biochemistry, Pharmaceutical Science, Apoptosis, Cell Cycle Proteins, Polo-like kinase, Protein Serine-Threonine Kinases, 01 natural sciences, Biochemistry, PLK1, PLK3, HeLa, 03 medical and health sciences, chemistry.chemical_compound, Protein Domains, Proto-Oncogene Proteins, Drug Discovery, Peptide synthesis, Humans, Amino Acid Sequence, Protein Kinase Inhibitors, Molecular Biology, biology, Caspase 3, 010405 organic chemistry, Kinase, Phosphopeptide, Tumor Suppressor Proteins, Organic Chemistry, biology.organism_classification, 0104 chemical sciences, G2 Phase Cell Cycle Checkpoints, 030104 developmental biology, chemistry, Drug Design, Molecular Medicine, Intracellular, HeLa Cells, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e3964f37e5cc33cbf264a315e0a156
https://doi.org/10.1016/j.bmc.2018.05.014

المؤلفون: López-Sánchez, Inmaculada, Sanz-García, Marta, Lazo, Pedro A.

مصطلحات موضوعية: VRK1, kinase, Plk3, phosphorylation

وصف الملف: 3127785 bytes; application/pdf

Relation: http://hdl.handle.net/10261/10708

الاتاحة: http://hdl.handle.net/10261/10708

المؤلفون: Xuan Xiao, Jinfeng Luo, Zhouling Xie, Kai Cheng, Yang Yang, Xing-Xing Zhang, Zhengchao Tu, Shiyu Li, Mei-Miao Zhan, Chenzhong Liao

المصدر: European Journal of Medicinal Chemistry. 143:724-731

مصطلحات موضوعية: 0301 basic medicine, Drug design, Antineoplastic Agents, Polo-like kinase, Protein Serine-Threonine Kinases, Pharmacology, PLK1, PLK3, Structure-Activity Relationship, 03 medical and health sciences, Cell Line, Tumor, Drug Discovery, Humans, Structure–activity relationship, MTT assay, Protein Kinase Inhibitors, Cell Proliferation, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Cell growth, Kinase, Pteridines, Organic Chemistry, General Medicine, 030104 developmental biology, Biochemistry, Drug Design, Drug Screening Assays, Antitumor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af52235a29d4d9899bf5417a0e057e52
https://doi.org/10.1016/j.ejmech.2017.11.058