المؤلفون: Hyun Soo Park, Valentino Laquintana, Sanghee Lee, Nunzio Denora, Su Bin Kim, Byung Chul Lee, Pietro Delre, Kyung-Min Kim, Seok Yong Lee, Sang Eun Kim, Antonio Lopalco, Annalisa Cutrignelli, Hye Won Kim, Massimo Franco, Giuseppe Felice Mangiatordi, Angela Lopedota, In Ho Song, Hyewon Youn

المصدر: European Journal of Nuclear Medicine and Molecular Imaging. 49:110-124

مصطلحات موضوعية: PK-11195, biology, Radiosynthesis, General Medicine, Ligand (biochemistry), Molecular biology, chemistry.chemical_compound, Non-competitive inhibition, chemistry, In vivo, Docking (molecular), Translocator protein, biology.protein, Radiology, Nuclear Medicine and imaging, Binding site

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::082251bdbd21096451c346222b51ca78
https://doi.org/10.1007/s00259-021-05617-4

المؤلفون: M. A. Yarkova, I. V. Rybina, A. S. Pantileev, S. B. Seredenin, O. A. Deeva, T. A. Gudasheva, A. G. Rebeko

المصدر: Pharmaceutical Chemistry Journal. 54:568-578

مصطلحات موضوعية: Pharmacology, PK-11195, Dipeptide, biology, 010405 organic chemistry, Ligand, Stereochemistry, medicine.drug_class, Methylamide, 01 natural sciences, Anxiolytic, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, chemistry, Amide, Drug Discovery, Translocator protein, biology.protein, medicine, Binding site

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::513261d1b6b3cb7c65c1d4bc60755330
https://doi.org/10.1007/s11094-020-02241-8

المؤلفون: Kupa, Léonard De Vinci Kanda

Thesis Advisors: Farsky, Sandra Helena Poliselli

مصطلحات موضوعية: Diazepam, G Protein coupled receptor, Inflamação, Inflammation, PK-11195, Receptor transmembrana ligado a proteína G, Ro5-4864, Toll like receptor, Toll-like receptor

وصف الملف: application/pdf

الاتاحة: http://www.teses.usp.br/teses/disponiveis/9/9141/tde-19102015-101109/

المؤلفون: Sheelu Monga, Moshe Gavish, Abraham Weizman

المصدر: Biology
Volume 9
Issue 9
Biology, Vol 9, Iss 291, p 291 (2020)

مصطلحات موضوعية: PK-11195, Chemokine, medicine.medical_treatment, CCL3, microglia, chemokines, CCL2, Pharmacology, CCL8, General Biochemistry, Genetics and Molecular Biology, CCL5, Article, chemistry.chemical_compound, Translocator protein, medicine, lcsh:QH301-705.5, General Immunology and Microbiology, biology, IL-2, CCL, Cytokine, chemistry, lcsh:Biology (General), inflammation, biology.protein, General Agricultural and Biological Sciences, TSPO

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3299cd29bac8e87164706f7d642447

المؤلفون: Tom Dixon, Alex Dickson, Arzu Uyar, Shelagh Ferguson-Miller

المصدر: Biophys J

مصطلحات موضوعية: PK-11195, Biophysics, Plasma protein binding, Ligands, 01 natural sciences, Molecular dynamics, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Receptors, GABA, 0103 physical sciences, Translocator protein, Receptor, Lipid bilayer, 030304 developmental biology, 0303 health sciences, 010304 chemical physics, biology, Drug discovery, Articles, Ligand (biochemistry), Isoquinolines, Receptor–ligand kinetics, Transition state, Transmembrane domain, chemistry, biology.protein, 030217 neurology & neurosurgery, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d279e1b13b467d7b280b26911a4a86
https://pubmed.ncbi.nlm.nih.gov/33221248

المؤلفون: Kumar Ajay, Muzik Otto, Shandal Varun, Chugani Diane, Chakraborty Pulak, Chugani Harry T

المصدر: Journal of Neuroinflammation, Vol 9, Iss 1, p 232 (2012)

مصطلحات موضوعية: Adults, Brain, Children, C-[R]-PK-11195 positron emission tomography, Glial cells, Inflammation, Microglia, Neuroinflammation, PBR, Peripheral benzodiazepine receptor, PK11195 PET, Translocator protein, TSPO, Neurology. Diseases of the nervous system, RC346-429

Relation: http://www.jneuroinflammation.com/content/9/1/232; https://doaj.org/toc/1742-2094; https://doaj.org/article/8cb91d79975446ec9c031003b2018183

الاتاحة: https://doi.org/10.1186/1742-2094-9-232
https://doaj.org/article/8cb91d79975446ec9c031003b2018183

المؤلفون: Ae Nim Pae, TaeHun Kim

المصدر: Expert Opinion on Therapeutic Patents. 26:1325-1351

مصطلحات موضوعية: 0301 basic medicine, Pathology, medicine.medical_specialty, PK-11195, Ro5-4864, Ligands, Pyrazolopyrimidine, Patents as Topic, Benzodiazepines, 03 medical and health sciences, chemistry.chemical_compound, Receptors, GABA, Drug Discovery, Translocator protein, medicine, Animals, Humans, Neuroinflammation, Pharmacology, biology, Neurodegenerative Diseases, General Medicine, Up-Regulation, Emapunil, Disease Models, Animal, 030104 developmental biology, chemistry, Drug Design, biology.protein, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb8f617a49648fa5e08626161df50436
https://doi.org/10.1080/13543776.2016.1230606

المؤلفون: Yingmin Liang, Judith C.W. Mak, Mary S.M. Ip, Yuting Cui

المصدر: Life Sciences. 265:118862

مصطلحات موضوعية: 0301 basic medicine, Mitochondrial ROS, PK-11195, Apoptosis, Bronchi, Inflammation, Mitochondrion, 030226 pharmacology & pharmacy, General Biochemistry, Genetics and Molecular Biology, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Receptors, GABA, Smoke, Tobacco, Translocator protein, medicine, Humans, General Pharmacology, Toxicology and Pharmaceutics, biology, Mitochondrial Permeability Transition Pore, Epithelial Cells, General Medicine, Isoquinolines, Subcellular localization, Mitochondria, Cell biology, 030104 developmental biology, chemistry, Mitochondrial permeability transition pore, Purines, biology.protein, medicine.symptom, Reactive Oxygen Species

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d238c1e0405824e8480e6a6af124d9
https://doi.org/10.1016/j.lfs.2020.118862

المؤلفون: Moshe Gavish, Leo Veenman, Maya Azrad, Abraham Weizman, Nidal Zeineh

المصدر: International Journal of Molecular Sciences, Vol 20, Iss 3, p 594 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 3

مصطلحات موضوعية: Lipopolysaccharides, PK-11195, Lipopolysaccharide, Blotting, Western, Pharmacology, TSPO ligands, Catalysis, Article, Nitric oxide, Cell Line, neuroinflammation, Inorganic Chemistry, lcsh:Chemistry, chemistry.chemical_compound, Mice, Receptors, GABA, medicine, Translocator protein, Animals, Physical and Theoretical Chemistry, microglial activation, Molecular Biology, inducible nitric oxide synthase (iNOS), nitric oxide (NO), lcsh:QH301-705.5, Spectroscopy, Neuroinflammation, Inflammation, Microglia, biology, Organic Chemistry, Neurotoxicity, General Medicine, medicine.disease, Isoquinolines, Computer Science Applications, cyclooxygenase-2 (COX-2), Nitric oxide synthase, medicine.anatomical_structure, chemistry, lcsh:Biology (General), lcsh:QD1-999, biology.protein, Quinazolines, Carbamates, lipopolysaccharide (LPS)

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::285f385e82d17a2577ff2c7f9825c7c8
https://www.mdpi.com/1422-0067/20/3/594

المؤلفون: He Wang, Zhengfan Gong, Chunyu Zeng, Duofen He, Hongmei Ren, Daqian Gu, Cuimei Hu, Lian-pan Wu, Tianyang Xia, Donghai Yang, Yu Han, Lin Zhou

المصدر: Life sciences. 221

مصطلحات موضوعية: 0301 basic medicine, Male, PK-11195, Intimal hyperplasia, Myocytes, Smooth Muscle, Pharmacology, Ligands, 030226 pharmacology & pharmacy, General Biochemistry, Genetics and Molecular Biology, Muscle, Smooth, Vascular, Diabetes Mellitus, Experimental, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Restenosis, Cell Movement, Diabetes mellitus, Neointima, medicine, Translocator protein, Animals, General Pharmacology, Toxicology and Pharmaceutics, Cells, Cultured, Cell Proliferation, Neointimal hyperplasia, Benzodiazepinones, Hyperplasia, biology, Cell growth, Chemistry, Cell migration, General Medicine, medicine.disease, Isoquinolines, Receptors, GABA-A, Rats, Disease Models, Animal, 030104 developmental biology, Carotid Arteries, cardiovascular system, biology.protein, Carrier Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b72c93cc460a3def4fafaaeead45381
https://pubmed.ncbi.nlm.nih.gov/30738868

المؤلفون: Moshe Gavish, Shiri Cohen, Rafael M. Nagler

المصدر: Journal of Cellular Biochemistry. 116:2786-2792

مصطلحات موضوعية: Saliva, PK-11195, biology, Cell, Cell Biology, Biochemistry, Molecular biology, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, medicine, Translocator protein, biology.protein, Saturation vapor curve, Inner mitochondrial membrane, Molecular Biology, Diazepam, medicine.drug, Free-radical theory of aging

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::01f91ff1e1a366ec40864217e6d7c98f
https://doi.org/10.1002/jcb.25221

المؤلفون: Federico Da Settimo, Talakad G. Lohith, Victor W. Pike, Sabrina Taliani, Sabrina Castellano, Stal Shrestha, Sanjay Telu, Sami S. Zoghbi, Masamichi Ikawa, Masahiro Fujita, Robert B. Innis

مصطلحات موضوعية: Adult, Male, Pathology, medicine.medical_specialty, PK-11195, positron emission tomography, Genotype, 18-kDa translocator protein (TSPO), 11C-ER176, Neurology, PET, Radiopharmaceuticals, XBD173, rs6971 polymorphism, Pharmacology, Sensitivity and Specificity, 030218 nuclear medicine & medical imaging, Diagnosis, Differential, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Positron emission tomography, Rs6971 polymorphism, Radiology, Nuclear Medicine and Imaging, Neuroimaging, Receptors, GABA, In vivo, Nuclear Medicine and Imaging, medicine, Translocator protein, Radioligand, Humans, Radiology, Nuclear Medicine and imaging, Carbon Radioisotopes, Observer Variation, biology, medicine.diagnostic_test, Chemistry, Binding potential, Brain, Reproducibility of Results, Human brain, Molecular Imaging, medicine.anatomical_structure, biology.protein, Female, Radiology, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf556c2c2f55a72d4d722b1a185866f4
http://hdl.handle.net/11386/4676450

المؤلفون: Ella Krayzler, Rafael M. Nagler, Avishai Gavish

المصدر: Experimental cell research. 350(1)

مصطلحات موضوعية: PK-11195, Cell Survival, Population, Biology, medicine.disease_cause, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Receptors, GABA, Cell Line, Tumor, medicine, Translocator protein, Humans, Inducer, Binding site, education, education.field_of_study, Binding Sites, Smoking, Cancer, Cell Biology, Ligand (biochemistry), medicine.disease, Isoquinolines, Molecular biology, chemistry, Biochemistry, 030220 oncology & carcinogenesis, biology.protein, Mouth Neoplasms, Carcinogenesis, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59660ede579fb5be379f021d52a62919
https://pubmed.ncbi.nlm.nih.gov/27939322

المؤلفون: Alana M. Scarf, Michael Kassiou, Claudia Martini, Chiara Guarino, E Da Pozzo, Silvia Selleri, Christopher Luus, Lars M. Ittner

المصدر: Scopus-Elsevier
Università degli studi di Firenze-IRIS

مصطلحات موضوعية: Lipopolysaccharides, PK-11195, translocator protein (TSPO), pyrrolobenzoxazepines, Allosteric regulation, Cooperativity, Plasma protein binding, Ligands, Nitric Oxide, Binding, Competitive, Biochemistry, GABA Antagonists, Benzodiazepines, chemistry.chemical_compound, Receptors, GABA, Species Specificity, Translocator protein, Animals, Humans, Binding site, Receptor, Molecular Biology, biology, HEK 293 cells, General Medicine, Isoquinolines, Mitochondria, Rats, HEK293 Cells, chemistry, Pregnenolone, biology.protein, Molecular Medicine, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d25d3b268e1ff4fa789e3c48d0f0ff
https://doi.org/10.2174/156652412800163460

المؤلفون: Ashish Dhir, Michael A. Rogawski

المصدر: British Journal of Pharmacology. 165:2684-2691

مصطلحات موضوعية: Pharmacology, Benzodiazepine, PK-11195, medicine.medical_specialty, Neuroactive steroid, biology, medicine.drug_class, GABAA receptor, GABA receptor antagonist, Clonazepam, chemistry.chemical_compound, Endocrinology, nervous system, chemistry, Internal medicine, Sedative, mental disorders, medicine, Translocator protein, biology.protein, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9d1c1b12ae3368bbdad699ada4899ddc
https://doi.org/10.1111/j.1476-5381.2011.01733.x

المؤلفون: Sylvie Bodard, Michael Kassiou, Katherine R. Leaver, Sylvie Chalon, Denis Guilloteau, Aaron J. Reynolds

المصدر: ACS Chemical Neuroscience. 3:114-119

مصطلحات موضوعية: Male, PK-11195, Microinjections, Physiology, Cognitive Neuroscience, Excitotoxicity, Pharmacology, medicine.disease_cause, Biochemistry, Neuroprotection, Rats, Sprague-Dawley, chemistry.chemical_compound, Image Processing, Computer-Assisted, Translocator protein, medicine, Animals, Dimethyl Sulfoxide, Neuroinflammation, Neurons, Cell Death, biology, Chemistry, Neurodegeneration, Cell Biology, General Medicine, Macrophage Activation, Quinolinic Acid, Isoquinolines, Receptors, GABA-A, medicine.disease, Immunohistochemistry, Rats, Astrogliosis, Neostriatum, Neuroprotective Agents, biology.protein, Microglia, Pharmaceutical Vehicles, Carrier Proteins, Quinolinic acid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1acd848b0daa9cf7940717cbef2d14c2
https://doi.org/10.1021/cn200099e

المؤلفون: Rafael M. Nagler, Ella Krayzler, Dana Savulescu, Moshe Gavish, Svetlana Leschiner, Leo Veenman

المصدر: Current Medicinal Chemistry. 17:2539-2546

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, PK-11195, Saliva, Cell Survival, Protein oxidation, medicine.disease_cause, Biochemistry, Young Adult, chemistry.chemical_compound, Receptors, GABA, Internal medicine, Drug Discovery, medicine, Translocator protein, Humans, Aged, Pharmacology, chemistry.chemical_classification, Reactive oxygen species, biology, Smoking, Organic Chemistry, Middle Aged, Isoquinolines, Ligand (biochemistry), Oxidative Stress, Endocrinology, chemistry, Toxicity, biology.protein, Molecular Medicine, Female, Oxidative stress, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c771b7aaadc894e865b0e34f32656c00
https://doi.org/10.2174/092986710791556050

المؤلفون: Georg Reiser, Dmitry Grachev, Olga Krestinina, Yulia Baburina, T. S. Azarashvili

المصدر: Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology. 4:43-49

مصطلحات موضوعية: Membrane potential, PK-11195, Biophysics, chemistry.chemical_element, Cell Biology, Mitochondrion, Calcium, Biology, Biochemistry, Cell biology, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, medicine, Phosphorylation, Protein phosphorylation, Binding site, Astrocyte

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1dba9685712cb7586ac4b5734e29295b
https://doi.org/10.1134/s1990747810010071

المؤلفون: Sandrine Guillou, Yves L. Janin

المساهمون: Chimie Organique, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Journal of Heterocyclic Chemistry
Journal of Heterocyclic Chemistry, Wiley, 2008, 45, pp.1377-1384. ⟨10.1002/jhet.5570450520⟩
Journal of Heterocyclic Chemistry, 2008, 45, pp.1377-1384. ⟨10.1002/jhet.5570450520⟩

مصطلحات موضوعية: chemistry.chemical_classification, Reaction conditions, PK-11195, [CHIM.ORGA]Chemical Sciences/Organic chemistry, 010405 organic chemistry, Organic Chemistry, chemistry.chemical_element, [SDV.CAN]Life Sciences [q-bio]/Cancer, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, 01 natural sciences, Combinatorial chemistry, 3. Good health, 0104 chemical sciences, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, chemistry, Ferrocene, 030220 oncology & carcinogenesis, Biological media, Benzodiazepine receptor ligands, Solubility, Alkyl, Palladium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e93217247378dd2fc32a5dd0e6e681
https://doi.org/10.1002/jhet.5570450520

المؤلفون: Jean Jacques Lacapère, Alejandro Luis Arregger, Mariano A. Ostuni, Omar R. Tumilasci, Vassilios Papadopoulos, Liliana Noemí Contreras, Gabriel Péranzi, Estela M. del Luján Cardoso

المصدر: Biology of the Cell. 100:427-439

مصطلحات موضوعية: Male, Saliva, PK-11195, Submandibular Gland, PK 11195, translocator protein (TSPO), Biology, Ciencias Biológicas, chemistry.chemical_compound, Biología Celular, Microbiología, medicine, Translocator protein, Animals, Salivary Ducts, Secretion, Rats, Wistar, Inner mitochondrial membrane, Receptor, Diazepam Binding Inhibitor, Neurotransmitter Agents, Mucous Membrane, salivary secretion, Biological Transport, Cell Biology, General Medicine, Isoquinolines, Receptors, GABA-A, peripheral benzodiazepine receptor (PBR), Ligand (biochemistry), Molecular biology, Submandibular gland, Rats, mitochondria, medicine.anatomical_structure, Biochemistry, chemistry, submandibular gland, Mitochondrial Membranes, biology.protein, Carrier Proteins, Salivation, CIENCIAS NATURALES Y EXACTAS, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d65b83ffc670a3b51cd6f90aad3d5c
https://doi.org/10.1042/bc20070157