المؤلفون: Bosch, Rolien, Petrone, Marcella, Arends, Rosalin, Vicini, Paolo, Sijbrands, Eric J.G., Hoefman, Sven, Snelder, Nelleke

المصدر: Bosch , R , Petrone , M , Arends , R , Vicini , P , Sijbrands , E J G , Hoefman , S & Snelder , N 2024 , ' Characterisation of cotadutide's dual GLP-1/glucagon receptor agonistic effects on glycaemic control using an in vivo human glucose regulation quantitative systems pharmacology model ' , British Journal of Pharmacology , vol. 181 , no. 12 , pp. 1874-1885 . https://doi.org/10.1111/bph.16336

مصطلحات موضوعية: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

الاتاحة: https://pure.eur.nl/en/publications/7ef1bfc8-ec4e-4ef1-965d-f64cc378a1c3
https://doi.org/10.1111/bph.16336
https://pure.eur.nl/ws/files/138759986/British_J_Pharmacology_-_2024_-_Bosch_-_Characterisation_of_cotadutide_s_dual_GLP_1_glucagon_receptor_agonistic_effects_on.pdf
http://www.scopus.com/inward/record.url?scp=85186570057&partnerID=8YFLogxK

المؤلفون: Dillon, Magnus T, Guevara, Jeane, Mohammed, Kabir, Patin, Emmanuel C, Smith, Simon A, Dean, Emma, Jones, Gemma N, Willis, Sophie E, Petrone, Marcella, Silva, Carlos, Thway, Khin, Bunce, Catey, Roxanis, Ioannis, Nenclares, Pablo, Wilkins, Anna, McLaughlin, Martin, Jayme-Laiche, Adoracion, Benafif, Sarah, Nintos, Georgios, Kwatra, Vineet, Grove, Lorna, Mansfield, David, Proszek, Paula, Martin, Philip, Moore, Luiza, Swales, Karen E, Banerji, Udai, Saunders, Mark P, Spicer, James, Forster, Martin D, Harrington, Kevin J

المصدر: Journal of Clinical Investigation , 134 (2) , Article e175369. (2024)

مصطلحات موضوعية: Cancer immunotherapy, DNA repair, Drug therapy, Oncology

وصف الملف: application/pdf

Relation: https://discovery.ucl.ac.uk/id/eprint/10185901/1/175369.2-20240109104717-covered-e0fd13ba177f913fd3156f593ead4cfd.pdf; https://discovery.ucl.ac.uk/id/eprint/10185901/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10185901/1/175369.2-20240109104717-covered-e0fd13ba177f913fd3156f593ead4cfd.pdf
https://discovery.ucl.ac.uk/id/eprint/10185901/

المؤلفون: Klein, Gernot, Petrone, Marcella, Yang, Ye, Hoang, Thuong, Hazlett, Sheila, Hansen, Lars, Flor, Armando

المساهمون: AstraZeneca

المصدر: Clinical Pharmacokinetics ; volume 62, issue 6, page 881-890 ; ISSN 0312-5963 1179-1926

الاتاحة: http://dx.doi.org/10.1007/s40262-023-01239-1
https://link.springer.com/content/pdf/10.1007/s40262-023-01239-1.pdf
https://link.springer.com/article/10.1007/s40262-023-01239-1/fulltext.html

المؤلفون: Bosch, Rolien, Petrone, Marcella, Arends, Rosalin, Vicini, Paolo, Sijbrands, Eric J.G., Hoefman, Sven, Snelder, Nelleke

المصدر: Bosch , R , Petrone , M , Arends , R , Vicini , P , Sijbrands , E J G , Hoefman , S & Snelder , N 2022 , ' A novel integrated QSP model of in vivo human glucose regulation to support the development of a glucagon/GLP-1 dual agonist ' , CPT: Pharmacometrics & Systems Pharmacology , vol. 11 , no. 3 , pp. 302-317 . https://doi.org/10.1002/psp4.12752

مصطلحات موضوعية: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

الاتاحة: https://pure.eur.nl/en/publications/14b3dc05-ef1a-40af-b0a2-205465981462
https://doi.org/10.1002/psp4.12752
https://pure.eur.nl/ws/files/88659549/A_novel_integrated_QSP_model_of_in_vivo_human_glucose_regulation_to_support_the_development_of_a_glucagonGLP_1_dual_agonist.pdf
http://www.scopus.com/inward/record.url?scp=85121647166&partnerID=8YFLogxK

المؤلفون: Parker, Victoria E.R., Hoang, Thuong, Schlichthaar, Heike, Gibb, Fraser W., Wenzel, Barbara, Posch, Maximillian G., Rose, Ludger, Chang, Yi Ting, Petrone, Marcella, Hansen, Lars, Ambery, Philip, Jermutus, Lutz, Heerspink, Hiddo J.L., McCrimmon, Rory J.

المصدر: Parker , V E R , Hoang , T , Schlichthaar , H , Gibb , F W , Wenzel , B , Posch , M G , Rose , L , Chang , Y T , Petrone , M , Hansen , L , Ambery , P , Jermutus , L , Heerspink , H J L & McCrimmon , R J 2022 , ' Efficacy and safety of cotadutide, a dual glucagon-like peptide-1 and glucagon receptor agonist, in a randomized phase 2a study of patients with type 2 diabetes and chronic kidney disease ' , Diabetes, Obesity ....

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/a120027e-a135-41ab-9975-74a0be41c76c
https://research.rug.nl/en/publications/a120027e-a135-41ab-9975-74a0be41c76c
https://doi.org/10.1111/dom.14712
https://pure.rug.nl/ws/files/622339384/Diabetes_Obesity_Metabolism_2022_Parker_Efficacy_and_safety_of_cotadutide_a_dual_glucagon_like_peptide_1_and.pdf

المؤلفون: Schofield, Darren J., Irving, Lorraine, Calo, Laura, Bogstedt, Anna, Rees, Gareth, Nuccitelli, Annalisa, Narwal, Rajesh, Petrone, Marcella, Roberts, Jennifer, Brown, Lee, Cusdin, Fiona, Dosanjh, Bhupinder, Lloyd, Christopher, Dobson, Claire, Gurrell, Ian, Fraser, Graham, McFarlane, Mary, Rockenstein, Edward, Spencer, Brian, Masliah, Eliezer, Spillantini, Maria Grazia, Tan, Keith, Billinton, Andrew, Vaughan, Tris, Chessell, Iain, Perkinton, Michael S.

المساهمون: AstraZeneca Pharmaceuticals and MedImmune

المصدر: Neurobiology of Disease ; volume 132, page 104582 ; ISSN 0969-9961

الاتاحة: http://dx.doi.org/10.1016/j.nbd.2019.104582
https://api.elsevier.com/content/article/PII:S0969996119302505?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0969996119302505?httpAccept=text/plain

المؤلفون: Ambery, Philip D., Klammt, Sebastian, Posch, Maximillian G., Petrone, Marcella, Pu, Wenji, Rondinone, Cristina, Jermutus, Lutz, Hirshberg, Boaz

المساهمون: MedImmune

المصدر: British Journal of Clinical Pharmacology ; volume 84, issue 10, page 2325-2335 ; ISSN 0306-5251 1365-2125

الاتاحة: http://dx.doi.org/10.1111/bcp.13688
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fbcp.13688
https://bpspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/bcp.13688

المؤلفون: Jain, Meena, Carlson, Glenn, Cook, William, Morrow, Linda, Petrone, Marcella, White, Nicholas E., Wang, Tao, Naylor, Jacqueline, Ambery, Philip, Lee, Charles, Hirshberg, Boaz

المساهمون: MedImmune LLC

المصدر: Diabetologia ; volume 62, issue 3, page 373-386 ; ISSN 0012-186X 1432-0428

الاتاحة: http://dx.doi.org/10.1007/s00125-018-4789-6
http://link.springer.com/article/10.1007/s00125-018-4789-6/fulltext.html
http://link.springer.com/content/pdf/10.1007/s00125-018-4789-6.pdf

المؤلفون: null Parker, Victoria E. R., null Hoang, Thuong, null Schlichthaar, Heike, null Gibb, Fraser W., null Wenzel, Barbara, null Posch, Maximillian G., null Rose, Ludger, null Chang, Yi-Ting, null Petrone, Marcella, null Hansen, Lars, null Ambery, Philip, null Jermutus, Lutz, null Heerspink, Hiddo J. L., null McCrimmon, Rory J.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::de79431db5b559513def31461c53862e
https://doi.org/10.1111/dom.14712/v2/response1

المؤلفون: Asano, Michiko, Sekikawa, Akiko, Kim, Hyosung, Gasser, Robert A., Robertson, Darren, Petrone, Marcella, Jermutus, Lutz, Ambery, Philip

المصدر: Diabetes, Obesity and Metabolism ; volume 23, issue 8, page 1859-1867 ; ISSN 1462-8902 1463-1326

الاتاحة: http://dx.doi.org/10.1111/dom.14412
https://onlinelibrary.wiley.com/doi/pdf/10.1111/dom.14412
https://onlinelibrary.wiley.com/doi/full-xml/10.1111/dom.14412

المؤلفون: Micheli, Fabrizio, Bonanomi, Giorgio, Braggio, Simone, Capelli, Anna Maria, Damiani, Federica, Di Fabio, Romano, Donati, Daniele, Gentile, Gabriella, Hamprecht, Dieter, Perini, Ornella, Petrone, Marcella, Tedesco, Giovanna, Terreni, Silvia, Worby, Angela, Heidbreder, Christian

المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 18, issue 3, page 908-912 ; ISSN 0960-894X

الاتاحة: https://doi.org/10.1016/j.bmcl.2007.12.042
https://api.elsevier.com/content/article/PII:S0960894X07015004?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0960894X07015004?httpAccept=text/plain

المؤلفون: Micheli, Fabrizio, Bonanomi, Giorgio, Braggio, Simone, Capelli, Anna Maria, Celestini, Paolo, Damiani, Federica, Fabio, Romano Di, Donati, Daniele, Gagliardi, Stefania, Gentile, Gabriella, Hamprecht, Dieter, Petrone, Marcella, Radaelli, Stefano, Tedesco, Giovanna, Terreni, Silvia, Worby, Angela, Heidbreder, Christian

المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 18, issue 3, page 901-907 ; ISSN 0960-894X

الاتاحة: https://doi.org/10.1016/j.bmcl.2007.12.066
https://api.elsevier.com/content/article/PII:S0960894X07015016?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0960894X07015016?httpAccept=text/plain

المؤلفون: Parker, Victoria E. R., Hoang, Thuong, Schlichthaar, Heike, Gibb, Fraser W., Wenzel, Barbara, Posch, Maximillian G., Rose, Ludger, Chang, Yi‐Ting, Petrone, Marcella, Hansen, Lars, Ambery, Philip, Jermutus, Lutz, Heerspink, Hiddo J. L., McCrimmon, Rory J.

المصدر: Diabetes, Obesity & Metabolism; Jul2022, Vol. 24 Issue 7, p1360-1369, 10p

المؤلفون: Micheli, Fabrizio, Bonanomi, Giorgio, Blaney, Frank E., Braggio, Simone, Capelli, Anna Maria, Checchia, Anna, Curcuruto, Ornella, Damiani, Federica, Di Fabio, Romano, Donati, Daniele, Gentile, Gabriella, Gribble, Andy, Hamprecht, Dieter, Tedesco, Giovanna, Terreni, Silvia, Tarsi, Luca, Lightfoot, Andrew, Stemp, Geoff, MacDonald, Gregor, Smith, Alex, Pecoraro, Michela, Petrone, Marcella, Perini, Ornella, Piner, Jacqui, Rossi, Tino, Worby, Angela, Pilla, Maria, Valerio, Enzo, Griffante, Cristiana, Mugnaini, Manolo, Wood, Martyn, Scott, Claire, Andreoli, Michela, Lacroix, Laurent, Schwarz, Adam, Gozzi, Alessandro, Bifone, Angelo, Ashby,, Charles R., Hagan, Jim J., Heidbreder, Christian

المصدر: Journal of Medicinal Chemistry ; volume 50, issue 21, page 5076-5089 ; ISSN 0022-2623 1520-4804

الاتاحة: https://doi.org/10.1021/jm0705612
https://pubs.acs.org/doi/pdf/10.1021/jm0705612

المؤلفون: Parker, Victoria E., Hoang, Thuong, Schlichthaar, Heike, Chang, Yi-Ting, Petrone, Marcella, Hansen, Lars, Ambery, Philip D., Heerspink, Hiddo J. L, Mccrimmon, Rory, Jermutus, Lutz

المصدر: Journal of the American Society of Nephrology ; volume 31, issue 10S, page 348-348 ; ISSN 1046-6673

الاتاحة: http://dx.doi.org/10.1681/asn.20203110s1348b
https://journals.lww.com/10.1681/ASN.20203110S1348b

المؤلفون: Lainé, Anne-Laure, Houvenagel, Sophie, Broo, Anders, Jones, Ian, Goodman, Joanne, Corkill, Dominic, Rose, Jonathan, Coward, Sam, Sandinge, Ann-Sofie, Petrone, Marcella, Jermutus, Lutz, Santos, Ana L Gomes Dos

المصدر: International Journal of Pharmaceutics ; volume 576, page 119019 ; ISSN 0378-5173

الاتاحة: http://dx.doi.org/10.1016/j.ijpharm.2020.119019
https://api.elsevier.com/content/article/PII:S0378517320300016?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0378517320300016?httpAccept=text/plain

المؤلفون: Floreani, Maura, Petrone, Marcella, Debetto, Patrizia, Palatini, Pietro

المصدر: Free Radical Research ; volume 26, issue 5, page 449-455 ; ISSN 1071-5762 1029-2470

الاتاحة: http://dx.doi.org/10.3109/10715769709084481
http://www.tandfonline.com/doi/pdf/10.3109/10715769709084481

المؤلفون: Ambery, Philip, Parker, Victoria E, Stumvoll, Michael, Posch, Maximilian G, Heise, Tim, Plum-Moerschel, Leona, Tsai, Lan-Feng, Robertson, Darren, Jain, Meena, Petrone, Marcella, Rondinone, Cristina, Hirshberg, Boaz, Jermutus, Lutz

المصدر: The Lancet ; volume 391, issue 10140, page 2607-2618 ; ISSN 0140-6736

الاتاحة: http://dx.doi.org/10.1016/s0140-6736(18)30726-8
https://api.elsevier.com/content/article/PII:S0140673618307268?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0140673618307268?httpAccept=text/plain

المؤلفون: Parker, Victoria E R, Robertson, Darren, Wang, Tao, Hornigold, David C, Petrone, Marcella, Cooper, Aidan T, Posch, Maximilian G, Heise, Tim, Plum-Moerschel, Leona, Schlichthaar, Heike, Klaus, Beate, Ambery, Philip D, Meier, Juris J, Hirshberg, Boaz

المصدر: The Journal of Clinical Endocrinology & Metabolism; March 2020, Vol. 105 Issue: 3 p803-820, 18p

المؤلفون: Jain, Meena, Carlson, Glenn, Cook, William, Morrow, Linda, Petrone, Marcella, White, Nicholas E., Wang, Tao, Naylor, Jacqueline, Ambery, Philip, Lee, Charles, Hirshberg, Boaz

المصدر: Diabetologia; Mar2019, Vol. 62 Issue 3, p373-386, 14p, 2 Diagrams, 8 Charts, 3 Graphs