يعرض 1 - 6 نتائج من 6 نتيجة بحث عن '"PDE4, phosphodiesterase 4"', وقت الاستعلام: 0.42s تنقيح النتائج
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    المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3060-3091 (2021)
    Acta Pharmaceutica Sinica. B

    مصطلحات موضوعية: RBD, receptor-binding domains, ARDS, MSC, mesenchymal stem cells, PLGA, poly(lactic-co-glycolic acid), MPO, myeloperoxidase, NAC, N-acetylcysteine, Review, ICAM-1, intercellular adhesion molecule-1, TNF-α, tumor necrosis factor-α, SDC1, syndecan-1, scFv, single chain variable fragments, PC, phosphatidylcholine, 0302 clinical medicine, EphA2, ephrin type-A receptor 2, BALF, bronchoalveolar lavage fluid, PECAM-1, platelet-endothelial cell adhesion molecule, Pathophysiologic feature, PEG, poly(ethylene glycol), Acute lung injury, cRGD, cyclic arginine glycine-D-aspartic acid, Respiratory function, General Pharmacology, Toxicology and Pharmaceutics, IKK, IκB kinase, PCB, poly(carboxybetaine), COVID-19, coronavirus disease 2019, HO-1, heme oxygenase-1, DPPC, dipalmitoylphosphatidylcholine, 0303 health sciences, EPCs, endothelial progenitor cells, Acute respiratory distress syndrome, TPP, triphenylphosphonium cation, RBC, red blood cells, SP, surfactant protein, EVs, extracellular vesicles, MPMVECs, mouse pulmonary microvascular endothelial cells, DOPE, phosphatidylethanolamine, ECM, extracellular matrix, CD, cyclodextrin, Nanomedicine, medicine.anatomical_structure, H2O2, hydrogen peroxide, 030220 oncology & carcinogenesis, Targeting strategy, Drug delivery, iNOS, inducible nitric oxide synthase, LPS, lipopolysaccharide, Esbp, E-selectin-binding peptide, NETs, neutrophil extracellular traps, medicine.medical_specialty, PS-PEG, poly(styrene-b-ethylene glycol), PDE4, phosphodiesterase 4, NF-κB, nuclear factor-κB, S1PLyase, sphingosine-1-phosphate lyase, RM1-950, ACE2, angiotensin-converting enzyme 2, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, Siglec, sialic acid-binding immunoglobulin-like lectin, GNP, peptide-gold nanoparticle, Anti-inflammatory therapy, Se, selenium, 03 medical and health sciences, PDA, polydopamine, ROS, reactive oxygen species, Pharmacotherapy, medicine, NE, neutrophil elastase, PEI, polyetherimide, SARS, severe acute respiratory syndrome, CLP, cecal ligation and perforation, TLR, toll-like receptor, Intensive care medicine, EPR, enhanced permeability and retention, FcgR, Fcγ receptor, AM, alveolar macrophages, ARDS, acute respiratory distress syndrome, YSA, YSAYPDSVPMMS, 030304 developmental biology, Lung, PEVs, platelet-derived extracellular vesicles, business.industry, AEC II, alveolar type II epithelial cells, MERS, Middle East respiratory syndrome, Therapeutic effect, COVID-19, DOTAP, 1-diolefin-3-trimethylaminopropane, medicine.disease, DOX, doxorubicin, IL, interleukin, rSPANb, anti-rat SP-A nanobody, Middle East respiratory syndrome, BSA, bovine serum albumin, SORT, selective organ targeting, Therapeutics. Pharmacology, Nanocarriers, ELVIS, Extravasation through Leaky Vasculature and subsequent Inflammatory cell-mediated Sequestration, business

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    المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3015-3034 (2021)
    Acta Pharmaceutica Sinica. B

    مصطلحات موضوعية: Target, ONRs, orphan nuclear receptors, Parkinson's disease, Small-molecule compound, MPP+, 1-methyl-4-phenylpyridinium, Autolysosome, GAPDH, glyceraldehyde 3-phosphate dehydrogenase, GBA, glucocerebrosidase β acid, Review, MPTP, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine, Disease, mTORC1, mTOR, the mammalian target of rapamycin, PD, Parkinson's disease, 0302 clinical medicine, CL, clearance rate, DAT, dopamine transporter, HDAC6, histone deacetylase 6, PD therapy, A2A, adenosine 2A, MYCBP2, MYC-binding protein 2, TFEB, transcription factor EB, AUTAC, autophagy targeting chimera, General Pharmacology, Toxicology and Pharmaceutics, SAS, solvent accessible surface, 0303 health sciences, α-syn, α-synuclein, ALP, autophagy-lysosomal pathway, AADC, aromatic amino acid decarboxylase, DJ-1, Parkinson protein 7, PI3K, phosphatidylinositol 3-kinase, COMT, catechol-O-methyltransferase, LUHMES, lund human mesencephalic, LRRK2, CMA, chaperone-mediated autophagy, KI, knockin, 030220 oncology & carcinogenesis, LRS, leucyl-tRNA synthetase, BBB, blood−brain barrier, SN, substantia nigra, IMPase, inositol monophosphatase, IPPase, inositol polyphosphate 1-phosphatase, HSPA8, heat shock 70 kDa protein 8, MAO-B, monoamine oxidase B, PREP, prolyl oligopeptidase, Parkinson's disease (PD), DR, dopamine receptor, PDE4, phosphodiesterase 4, AMPK, 5ʹAMP-activated protein kinase, 5-HT2C, serotonin 2C, SNCA, α-synuclein gene, TSC2, tuberous sclerosis complex 2, RM1-950, LIMP-2, lysosomal integrated membrane protein-2, CNS, central nervous system, 5-HT2A, Serotonin 2A, ER, endoplasmic reticulum, ATG, autophagy related protein, 03 medical and health sciences, PLC, phospholipase C, ROS, reactive oxygen species, ERRα, estrogen-related receptor alpha, SAR, structure–activity relationship, ULK1, UNC-51-like kinase 1, medicine, Autophagy, NMDA, N-methyl-d-aspartic acid, mAChR, muscarinic acetylcholine receptor, GWAS, genome-wide association study, LAMP2A, lysosome-associated membrane protein 2 A, Lamp2a, type 2A lysosomal-associated membrane protein, 030304 developmental biology, Parkin, parkin RBR E3 ubiquitin−protein ligase, PINK1, PTEN-induced kinase 1, ATTEC, autophagosome-tethering compound, ATP13A2, ATPase cation transporting 13A2, business.industry, ULK1, medicine.disease, LC3, light chain 3, PI3P, phosphatidylinositol 3-phosphate, SYT11, synaptotagmin 11, AUC, the area under the curve, UPS, ubiquitin−proteasome system, TFEB, DA, dopamine, Therapeutics. Pharmacology, business, BAF, bafilomycinA1, HSC70, heat shock cognate 71 kDa protein, Neuroscience, 3-MA, 3-methyladenine, F, oral bioavailability, LRRK2, leucine-rich repeat sequence kinase 2

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    المصدر: Metabolism

  6. 6

    المصدر: Bradshaw, N J & Porteous, D J 2012, ' DISC1-binding proteins in neural development, signalling and schizophrenia ', Neuropharmacology, vol. 62, no. 3, pp. 1230-41 . https://doi.org/10.1016/j.neuropharm.2010.12.027
    Neuropharmacology

    مصطلحات موضوعية: Scaffold protein, BACE1, β-site APP-cleaving enzyme-1, PCM1, Pericentriolar material 1, PSD, Post-synaptic density, Neurodevelopment, FEZ1, Fasciculation and elongation protein zeta 1, 0302 clinical medicine, PDE4B, CEP290, Centrosomal protein 290 kDa, Copy-number variation, NDE1, Nuclear distribution factor E homologue 1 or Nuclear distribution element 1, 0303 health sciences, LEF/TCF, Lymphoid enhancer factor/T cell factor, biology, Kal7, Kalirin-7, LIS1, Lissencephaly 1, ATF4, Activating transcription factor 4, PACAP, Pituitary adenylate cyclase-activating polypeptide, DISC1, Schizophrenia, Signalling, Synapse, Association studies, 3. Good health, GluR, Glutamate receptor, PDE4, Phosphodiesterase 4, CRE, cAMP response element, Neural development, Signal Transduction, CNV, Copy number variation, Neurogenesis, Schizophrenia (object-oriented programming), Nerve Tissue Proteins, Article, 03 medical and health sciences, Cellular and Molecular Neuroscience, PCNT, Pericentrin, GSK3β, Glycogen synthase kinase 3β, Animals, Humans, DBZ, DISC1-binding zinc finger, DISC1, Disrupted in schizophrenia 1, 030304 developmental biology, Pharmacology, BBS4, Bardet–Biedl syndrome 4, NDEL1, PI3 K, Phosphatidylinositiol 3-kinase, Rac1, Ras-related C3 botulinum toxin substrate 1, TNIK, Traf2 and Nck interacting kinase, mTOR, Mammalian target of rapamycin, Dixdc1, Dishevelled-axin domain containing-1, TNIK, NRG, Neuregulin, biology.protein, Carrier Proteins, APP, Amyloid precursor protein, Neuroscience, NDEL1, NDE-like 1, 030217 neurology & neurosurgery

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