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المؤلفون: Xiaoxiao Wang, Junxiang Ji, Xin Wang, Yuting Li, Meng Zhang, Yan Zhang, Zhenhua Zhu, Shou-Dong Ye, Yang Yu, Xinbao Zhang
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: MAPK/ERK pathway, Homeobox protein NANOG, Embryonic stem cells, Benzylamines, MAP Kinase Signaling System, Induced Pluripotent Stem Cells, CS, CHIR99021 and Spautin-1, self-renewal, Raf1, v-raf-leukemia viral oncogene 1, Biochemistry, Cell Line, Mice, mESCs, mouse embryonic stem cells, Tfcp2l1, transcription factor CP2-like 1, CHIR, CHIR99021, USP10, ubiquitin-specific peptidase 10, Animals, Humans, USP13, ubiquitin-specific peptidase 13, Progenitor cell, Raf1, Induced pluripotent stem cell, Molecular Biology, Spautin-1, Nanog, Nanog homeobox, Chemistry, MEK inhibitor, LIF, leukemia inhibitory factor, iPSCs, induced pluripotent stem cells, qRT-PCR, quantitative real-time PCR, USP13, Mouse Embryonic Stem Cells, Cell Biology, shRNA, the short hairpin RNA, PB, PiggyBac system, Embryonic stem cell, Cell biology, Proto-Oncogene Proteins c-raf, AP, alkaline phosphatase, Oct4, POU domain, class 5, transcription factor 1, Cell culture, Quinazolines, EpiSCs, epiblast stem cells, Ubiquitin-Specific Proteases, Stem cell, Research Article
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المؤلفون: Yuting Li, Junxiang Ji, Meng Zhang, Qian Ban, Xinbao Zhang, Xiaoxiao Wang, Yan Zhang, Shou-Dong Ye, Xiaofeng Li, Xin Wang
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: iMeLCs, incipient mesoderm-like cells, Stem cell factor, Biochemistry, Mice, FACS, fluorescence-activated cell sorting, Tfcp2l1, transcription factor CP2-like 1, Oct4, octamer-binding transcription factor 4, Induced pluripotent stem cell, Prdm14, PR domain zinc finger protein 14, Zinc finger, primordial germ cell–like cells, LIF, leukemia inhibitory factor, Wnt signaling pathway, iPSCs, induced pluripotent stem cells, qRT-PCR, quantitative real-time PCR, embryonic stem cells, KSR, KnockOut Serum Replacement, Cell biology, ChIP, chromatin immunoprecipitation, medicine.anatomical_structure, EpiSCs, epiblast stem cells, Germ cell, Research Article, Pluripotent Stem Cells, Transcription Factor AP-2-Gamma, DOX, doxycycline, Prdm14, Biology, Cell Line, Protein Domains, i-Tfcp2l1, inducible Tfcp2l1, PGCs, primordial germ cells, medicine, Animals, Humans, Molecular Biology, Transcription factor, PB, PiggyBac, EGF, epidermal growth factor, SCF, stem cell factor, TFCP2l1, BMP, bone morphogenetic protein, Cell Biology, ESCs, embryonic stem cells, Embryonic stem cell, Repressor Proteins, Germ Cells, Blimp1, B lymphocyte–induced maturation protein-1, ROCK, Rho-associated protein kinase, Tfap2c, transcription factor AP-2 gamma, Wnt, wingless/integrated, PGCLCs, PGC-like cells, EpiLCs, epiblast-like cells, Transcription Factors
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المؤلفون: Han Dong, Jianzhu Chen, James Dongjoo Ham, Romee Rizwan, Guozhu Xie, Yong Liang
المصدر: EBioMedicine, Vol 59, Iss, Pp 102975-(2020)
EBioMedicine
Elsevierمصطلحات موضوعية: 0301 basic medicine, MDSCs, myeloid-derived suppressor cells, medicine.medical_treatment, TAM, tumour-associated macrophages, Cell Culture Techniques, Cell- and Tissue-Based Therapy, lcsh:Medicine, Review, NK cells, GVHD, graft-versus-host disease, Immunotherapy, Adoptive, 0302 clinical medicine, ADCC, antibody-dependent cell-mediated cytotoxicity, GMP, good manufacturing practice, NK, Natural killer, Neoplasms, TIL, tumour-infiltrating lymphocyte, TME, tumour microenvironment, Cytotoxic T cell, ADCP, antibody-dependent cellular phagocytosis, Chimeric antigen receptor, TIRs, terminal inverted repeats, Cancer, Clinical Trials as Topic, lcsh:R5-920, Receptors, Chimeric Antigen, CAR-NK, CAR-engineered NK, TCR, T cell receptor, NCRs, natural cytotoxicity receptors, iPSCs, induced pluripotent stem cells, LAK, lymphokine-activated killer, General Medicine, CAR, Chimeric antigen receptor, CRS, cytokine release syndrome, VEGF, vascular endothelial growth factor, TCR-T, TCR-engineered T, Killer Cells, Natural, Treatment Outcome, Batch Cell Culture Techniques, 030220 oncology & carcinogenesis, Tregs, regulatory T cells, SB, sleeping beauty, APCs, antigen-presenting cells, Immunotherapy, Genetic Engineering, lcsh:Medicine (General), AML, acute myeloid leukaemia, IgG, immunoglobulin G, General Biochemistry, Genetics and Molecular Biology, CAR-T, CAR-engineered T, CAR-Ms, macrophages with CARs, 03 medical and health sciences, Immune system, Antigen, PB NK, PBMCs-derived NK, SBRT, stereotactic body radiotherapy, Antigens, Neoplasm, KIRs, killer cell Ig-like receptors, HPCs, hematopoietic progenitor cells, medicine, Animals, Humans, Antigen-presenting cell, PB, PiggyBac, PBMCs, peripheral blood mononuclear cells, business.industry, SCF, stem cell factor, BMP4, bone morphogenetic protein 4, lcsh:R, ITAM, immunoreceptor tyrosine-based activation motif, scFv, single-chain variable fragment, UCB, umbilical cord blood, 030104 developmental biology, Myeloid-derived Suppressor Cell, Cancer research, business, BaEV-gp, baboon envelop glycoprotein, human activities, CD8
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المؤلفون: Rico Chandra Ardy, Paul J. Coffer, Klaske D. Lichtenbelt, Henkjan J. Verkade, Edward E. S. Nieuwenhuis, Thomas Müller, Jorik M. van Rijn, Zeren Baris, Edwin C. A. Stigter, Rene Scheenstra, Zarife Kuloğlu, Marini Thian, Hubert P. J. van der Doef, Bettina Härter, Marliek van Hoesel, Dorien Lugtenberg, Figen Özçay, Sabine Middendorp, Aysel Ünlüsoy Aksu, Henricus G.F. Brouwer, Buket Dalgic, Gijs van Haaften, Roderick H. J. Houwen, Peter G. J. Nikkels, Meryem Keçeli Başaran, Andreas R. Janecke, Joke B. G. M. Verheij, Anke H.M. van Vugt, Kaan Boztug, Freddy T. M. Kokke, Aydan Kansu, Maarten P.G. Massink, Renate Kain, Bart Spee, Karen Duran, Neslihan Gurcan Kaya, Désirée Y. van Haaften-Visser, Ana Krolo
المساهمون: Onderzoek, dCSCA RMSC-1, Sub Biomolecular analysis, Center for Liver, Digestive and Metabolic Diseases (CLDM), Lifestyle Medicine (LM)
المصدر: Gastroenterology, 155(1), 130. W.B. Saunders Ltd
Gastroenterology, 155, 130-143.e15
Gastroenterology, 155, 1, pp. 130-143.e15
Gastroenterology
Gastroenterology, 155(1), 130-143. W B SAUNDERS CO-ELSEVIER INCمصطلحات موضوعية: Male, 0301 basic medicine, OBESITY RESISTANCE, DISORDER, 3-D Culture Model, Lipid Metabolism Disorder, Malabsorption, Turkey, PROTEIN-LOSING ENTEROPATHY, Lipid Metabolism Disorders, Sensory disorders Donders Center for Medical Neuroscience [Radboudumc 12], DISEASE, Consanguinity, 0302 clinical medicine, Lipid droplet, DG, diacylglycerol, ABSORPTION, B-LCL, B lymphoblastoid cell line, Child, MUTATION, Netherlands, Caspase 7, Caspase 3, Gastroenterology, High-Throughput Nucleotide Sequencing, HUMANS, Dermis, GI, gastrointestinal, Intestinal epithelium, TG, triacylglycerol, 3. Good health, FAMILY, Organoids, Lipotoxicity, hSI-EM, human small intestine expansion medium, Child, Preschool, Female, 030211 gastroenterology & hepatology, COA-DIACYLGLYCEROL ACYLTRANSFERASE-1, medicine.medical_specialty, Duodenum, DGAT1, diacylglycerol-acyltransferase 1, PLE, Protein-Losing Enteropathies, sgRNA, single-guide RNA, PBS, phosphate-buffered saline, Real-Time Polymerase Chain Reaction, Article, cDNA, complementary DNA, 03 medical and health sciences, PLE, protein-losing enteropathy, All institutes and research themes of the Radboud University Medical Center, Internal medicine, FFA, free fatty acid, medicine, Organoid, Diacylglycerol O-Acyltransferase, CDD, congenital diarrheal disorder, Hepatology, business.industry, OA, oleic acid, Lipid metabolism, Sequence Analysis, DNA, Fibroblasts, medicine.disease, COMBINED IMMUNODEFICIENCY, Phorbols, WT, wild-type, 030104 developmental biology, Endocrinology, SSC, Side Scatter, Case-Control Studies, PB, PiggyBac transposon, Genomic, BSA, bovine serum albumin, Caco-2 Cells, Intestinal Disorder, business, Hypoalbuminemia, CDD
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