المؤلفون: BERNICE M. T. LAM, BETTINA BAZZINI, BURTON G. CHRISTENSEN, DANE E. KARR, ELIZABETH SORIANO, J. KEVIN JUDICE, JENG-PYNG SHAW, JENNY D. VILLENA, JOHN L. PACE, KELLY QUAST, KEVIN M. KRAUSE, MARTIN S. LINSELL, MATTHEW B. NODWELL, MICHAEL R. LEADBETTER, PAUL R. FATHEREE, SEAN G. TRAPP, STACY M. ADAMS, TERRY X. WU

المصدر: The Journal of Antibiotics. 2004, 57(5):326

المؤلفون: Whitney Krey-Epstein, Elad Kaufman, Erik Sandvik, Susan L. Calhoun, Paul R. Fatheree, Melanie A. Kleinschek, Joe Budman, Emma Gordon, Reuben Sana

المصدر: Airway pharmacology and treatment.

مصطلحات موضوعية: business.industry, Kinase, medicine.medical_treatment, Periostin, Eosinophil, Pharmacology, Cytokine, medicine.anatomical_structure, Tyrosine kinase 2, medicine, CCL17, Phosphorylation, CCL26, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9d512718c1b46176363dbb72f3bfe87f
https://doi.org/10.1183/13993003.congress-2019.pa3872

المؤلفون: Craig M. Hill, Donavon McConn, Laxminarayan G Hegde, Roland Gendron, Brooke Blair, Keith Jendza, Joe Budman, Paul R. Fatheree, Daniel Marquess, R. Murray McKinnell, Cecile Yu, Sharath S. Hegde, Seok-Ki Choi, Uwe Klein

مصطلحات موضوعية: Angiotensin II receptor type 1, Angioedema, 010405 organic chemistry, business.industry, Organic Chemistry, fungi, Antagonist, Bradykinin, Pharmacology, 01 natural sciences, Biochemistry, Angiotensin II, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, Losartan, chemistry, Drug Discovery, medicine, Omapatrilat, medicine.symptom, business, Neprilysin, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ec5793446e9f5c0388334fd310b518
https://europepmc.org/articles/PMC6331171/

المؤلفون: Jeng-Pyng Shaw, Daniel Marquess, R. Murray McKinnell, Paul R. Fatheree, David Beattie, Scott R. Armstrong, Daniel D. Long, Ross G. Vickery

المصدر: Bioorganic & Medicinal Chemistry Letters. 23:4210-4215

مصطلحات موضوعية: Male, Agonist, Benzimidazole, Intrinsic activity, medicine.drug_class, Stereochemistry, Guinea Pigs, Clinical Biochemistry, Drug Evaluation, Preclinical, Molecular Conformation, Pharmaceutical Science, Pharmacology, Crystallography, X-Ray, Biochemistry, Rats, Sprague-Dawley, Serotonin 5-HT4 Receptor Agonists, chemistry.chemical_compound, Dogs, Piperidines, Drug Discovery, medicine, Animals, Protein Isoforms, Intestinal Mucosa, Receptor, Molecular Biology, 5-HT receptor, Chemistry, Organic Chemistry, In vitro, Rats, Molecular Medicine, Benzimidazoles, Receptors, Serotonin, 5-HT4, Linker, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0643983a830ed44b26b2d665107333f
https://doi.org/10.1016/j.bmcl.2013.05.018

المؤلفون: Roopa Rai, Kyle Elrod, William D. Shrader, James W. Janc, Yong Li, Lynne Cregar, Wendy B. Young, Aleksandr Kolesnikov, Thomas E. Jenkins, Paul R. Fatheree, Brad A. Katz, Erik Verner, Paul A. Sprengeler

المصدر: Bioorganic & Medicinal Chemistry Letters. 16:710-713

مصطلحات موضوعية: Proteases, medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Crystallography, X-Ray, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Thrombin, Drug Discovery, Antithrombotic, medicine, Protease Inhibitors, Protease inhibitor (pharmacology), Blood Coagulation, Molecular Biology, Chelating Agents, Protease, Factor VII, biology, Organic Chemistry, Anticoagulants, Zinc, chemistry, Coagulation, Enzyme inhibitor, biology.protein, Molecular Medicine, Factor Xa Inhibitors, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890f430c3bb6f05e6bfb08f3695a2bf1
https://doi.org/10.1016/j.bmcl.2005.10.023

المؤلفون: Paul R. Fatheree, Jacqueline A.M. Smith, Patrick P. Humphrey, David Beattie, S. Derek Turner, Seok-Ki Choi, Roland Gendron, Daniel Marquess, Goldblum Adam A, Ross G. Vickery, Jeng Pyng Shaw, Scott R. Armstrong, Daniel D. Long, Lan Jiang, Daniel Genov

المصدر: Bioorganicmedicinal chemistry letters. 22(19)

مصطلحات موضوعية: Agonist, medicine.medical_specialty, medicine.drug_class, Clinical Biochemistry, Guinea Pigs, Pharmaceutical Science, 5-HT4 receptor, Pharmacology, Biochemistry, chemistry.chemical_compound, Serotonin 5-HT4 Receptor Agonists, Structure-Activity Relationship, Pharmacokinetics, In vivo, Internal medicine, Drug Discovery, medicine, Potency, Animals, Humans, Velusetrag, Receptor, Molecular Biology, Molecular Structure, Chemistry, Drug discovery, Organic Chemistry, Rats, Endocrinology, Chronic Disease, Molecular Medicine, Receptors, Serotonin, 5-HT4, Azabicyclo Compounds, Constipation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98dc3bfd1562242be0ff583154f8c9fe
https://pubmed.ncbi.nlm.nih.gov/22959244

المؤلفون: David Beattie, Daniel D. Long, S. Derek Turner, Paul R. Fatheree, Jacqueline A.M. Smith, Scott R. Armstrong, Seok-Ki Choi, Roland Gendron, Jeng Pyng Shaw, Goldblum Adam A, Daniel Marquess, Ross G. Vickery, Patrick P. Humphrey

المصدر: Bioorganicmedicinal chemistry letters. 22(14)

مصطلحات موضوعية: Agonist, Male, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Administration, Oral, Pharmacology, Biochemistry, Partial agonist, Piperazines, Cell Line, Rats, Sprague-Dawley, Serotonin 5-HT4 Receptor Agonists, Structure-Activity Relationship, In vivo, Heterocyclic Compounds, Drug Discovery, Enzyme-linked receptor, medicine, Potency, Inverse agonist, Animals, Humans, Receptor, Molecular Biology, Molecular Structure, Drug discovery, Chemistry, Organic Chemistry, musculoskeletal system, Rats, Organ Specificity, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d91c6df1bb3ebe20770d405356021a
https://pubmed.ncbi.nlm.nih.gov/22683222

المؤلفون: Scott R. Armstrong, Seok-Ki Choi, Jeng-Pyng Shaw, David Beattie, Goldblum Adam A, S. Derek Turner, Daniel D. Long, R. Murray McKinnell, Ross G. Vickery, Daniel Marquess, Paul R. Fatheree, Jacqueline A.M. Smith, Roland Gendron, Patrick P. Humphrey

المصدر: Journal of medicinal chemistry. 52(17)

مصطلحات موضوعية: Agonist, Male, Tegaserod, medicine.drug_class, Gastrointestinal Diseases, Movement, 5-HT4 receptor, Administration, Oral, Biological Availability, Pharmacology, Piperazines, Cell Line, Substrate Specificity, Rats, Sprague-Dawley, Serotonin 5-HT4 Receptor Agonists, Dogs, Oral administration, Drug Discovery, medicine, Animals, Humans, Binding site, Receptor, chemistry.chemical_classification, Binding Sites, Chemistry, Sulfonamide, Rats, Biochemistry, Drug Design, Molecular Medicine, Receptors, Serotonin, 5-HT4, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4688cb8658e9c717a833552ee059467
https://pubmed.ncbi.nlm.nih.gov/19663444

المؤلفون: Sharath S. Hegde, Matthew B. Nodwell, Martin S. Linsell, Kevin M. Krause, Paul R. Fatheree, Daniel Marquess, David W. Green, John L. Pace, James B. Aggen, Koné Kaniga, Sean G. Trapp, Jason P. Chinn, Seok-Ki Choi, J. Kevin Judice, Burton G. Christensen, Michael R. Leadbetter, S. Derek Turner, Daniel D. Long, Edmund J. Moran

المصدر: The Journal of antibiotics. 61(10)

مصطلحات موضوعية: Methicillin-Resistant Staphylococcus aureus, Magnetic Resonance Spectroscopy, medicine.drug_class, Cephalosporin, Antibiotics, Microbial Sensitivity Tests, medicine.disease_cause, Gram-Positive Bacteria, beta-Lactams, Microbiology, chemistry.chemical_compound, Mice, In vivo, Drug Discovery, medicine, Animals, Pharmacology, Molecular Structure, Chemistry, Glycopeptides, biochemical phenomena, metabolism, and nutrition, Methicillin-resistant Staphylococcus aureus, Glycopeptide, Anti-Bacterial Agents, Cephalosporins, Staphylococcus aureus, Drug Design, Lactam, Vancomycin, Female, Dimerization, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f61df8c63b20c8ea01fd57019b7448c
https://pubmed.ncbi.nlm.nih.gov/19168974

المؤلفون: R. Murray McKinnell, Scott R. Armstrong, David T. Beattie, Seok-Ki Choi, Paul R. Fatheree, Roland A. L. Gendron, Adam Goldblum, Patrick P. Humphrey, Daniel D. Long, Daniel G. Marquess, J. P. Shaw, Jacqueline A. M. Smith, S. Derek Turner, Ross G. Vickery

المصدر: Journal of Medicinal Chemistry; Sep2009, Vol. 52 Issue 17, p5330-5343, 14p