يعرض 1 - 10 نتائج من 10 نتيجة بحث عن '"PANELLA, ANDREA"', وقت الاستعلام: 0.41s تنقيح النتائج
  1. 1
    Academic Journal
    Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6)

    المؤلفون: CINGOLANI, GINO, PANELLA, ANDREA, PERRONE, MARIA GRAZIA, VITALE, PAOLA, Di Mauro, Giuseppe, Fortuna, Cosimo G., Armen, Roger S., FERORELLI, Savina, Smith, William L., SCILIMATI, Antonio

    المساهمون: Cingolani, Gino, Panella, Andrea, Perrone, MARIA GRAZIA, Vitale, Paola, Di Mauro, Giuseppe, Fortuna, Cosimo G., Armen, Roger S., Ferorelli, Savina, Smith, William L., Scilimati, Antonio

    مصطلحات موضوعية: Cyclooxygenase-1 inhibition, Mofezolac, P6, Diarylisoxazole, X-ray crystallography, Molecular modelling

    Relation: info:eu-repo/semantics/altIdentifier/pmid/28710965; info:eu-repo/semantics/altIdentifier/wos/WOS:000411297000052; volume:138; firstpage:661; lastpage:668; numberofpages:8; journal:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY; http://hdl.handle.net/11586/198491; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85022319489; http://www.journals.elsevier.com/european-journal-of-medicinal-chemistry/

    الاتاحة: http://hdl.handle.net/11586/198491
    https://doi.org/10.1016/j.ejmech.2017.06.045
    http://www.journals.elsevier.com/european-journal-of-medicinal-chemistry/

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  2. 2
    Academic Journal
    Structural Elucidation of Cisplatin and Hydrated cis-Diammineplatinum(II) Complex Conjugated with Cyanocobalamin by Liquid Chromatography with Electrospray Ionization–Mass Spectrometry and Multistage Mass Spectrometry

    المؤلفون: Ventura, Giovanni, Nardella, Maria Incoronata, Panella, Andrea, Arnesano, Fabio, Calvano, Cosima Damiana, Losito, Ilario, Palmisano, Francesco, Cataldi, Tommaso R. I.

    المساهمون: Ministero dell?Istruzione, dell?Universit? e della Ricerca

    المصدر: ACS Omega ; volume 3, issue 10, page 12914-12922 ; ISSN 2470-1343 2470-1343

    الاتاحة: http://dx.doi.org/10.1021/acsomega.8b01879
    http://pubs.acs.org/doi/pdf/10.1021/acsomega.8b01879
    https://pubs.acs.org/doi/pdf/10.1021/acsomega.8b01879

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  3. 3
    Academic Journal
    Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs)

    المؤلفون: PERRONE, MARIA GRAZIA, VITALE, PAOLA, PANELLA, ANDREA, FERORELLI, Savina, CONTINO, MARIALESSANDRA, Lavecchia, Antonio, SCILIMATI, Antonio

    المساهمون: Perrone, MARIA GRAZIA, Vitale, Paola, Panella, Andrea, Ferorelli, Savina, Contino, Marialessandra, Lavecchia, Antonio, Scilimati, Antonio

    مصطلحات موضوعية: molecular docking · decomposition analysis, cyclooxygenase · isoxazoles · P-glycoprotein

    Relation: info:eu-repo/semantics/altIdentifier/pmid/27136372; info:eu-repo/semantics/altIdentifier/wos/WOS:000380023100009; volume:11; issue:11; firstpage:1172; lastpage:1187; numberofpages:16; journal:CHEMMEDCHEM; http://hdl.handle.net/11586/165280; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85006224644; http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1860-7187

    الاتاحة: http://hdl.handle.net/11586/165280
    https://doi.org/10.1002/cmdc.201500439
    http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1860-7187

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  4. 4
    Academic Journal
    COX-1 Inhibitors: Beyond Structure Toward Therapy

    المؤلفون: VITALE, PAOLA, PANELLA, ANDREA, SCILIMATI, Antonio, PERRONE, MARIA GRAZIA

    المساهمون: Vitale, Paola, Panella, Andrea, Scilimati, Antonio, Perrone, MARIA GRAZIA

    مصطلحات موضوعية: COX-1 inhibitor, natural compounds and dietary phytochemical, docking studie, neuroinflammation, ovarian cancer

    Relation: info:eu-repo/semantics/altIdentifier/pmid/27111555; info:eu-repo/semantics/altIdentifier/wos/WOS:000379150700002; volume:36; issue:4; firstpage:641; lastpage:671; numberofpages:31; journal:MEDICINAL RESEARCH REVIEWS; http://hdl.handle.net/11586/165260; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84974678249; http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1098-1128

    الاتاحة: http://hdl.handle.net/11586/165260
    https://doi.org/10.1002/med.21389
    http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1098-1128

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  5. 5
    Academic Journal
    General role of the amino and methylsulfamoyl groups in selective cyclooxygenase(COX)-1 inhibition by 1,4-diaryl-1,2,3-triazoles and validation of a predictive pharmacometric PLS model

    المؤلفون: PERRONE, MARIA GRAZIA, VITALE, PAOLA, PANELLA, ANDREA, Fortuna, Cosimo G., SCILIMATI, Antonio

    المساهمون: Perrone, MARIA GRAZIA, Vitale, Paola, Panella, Andrea, Fortuna, Cosimo G., Scilimati, Antonio

    مصطلحات موضوعية: 1,2,3-Triazole, COX inhibition, Predictive pharmacometric model, Volsurf plu, Drug Discovery3003 Pharmaceutical Science, Organic Chemistry, Pharmacology

    Relation: info:eu-repo/semantics/altIdentifier/pmid/25768707; info:eu-repo/semantics/altIdentifier/wos/WOS:000353730900023; volume:94; firstpage:252; lastpage:264; numberofpages:13; journal:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY; http://hdl.handle.net/11586/143123; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84924696954; http://www.journals.elsevier.com/european-journal-of-medicinal-chemistry/

    الاتاحة: http://hdl.handle.net/11586/143123
    https://doi.org/10.1016/j.ejmech.2015.02.049
    http://www.journals.elsevier.com/european-journal-of-medicinal-chemistry/

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  6. 6
    Book
    Current and emerging applications of fluorine in medicinal chemistry

    المؤلفون: PERRONE, MARIA GRAZIA, VITALE, PAOLA, PANELLA, ANDREA, Tolomeo, Anna, SCILIMATI, Antonio

    المساهمون: Westwell, A.D., Perrone, MARIA GRAZIA, Vitale, Paola, Panella, Andrea, Tolomeo, Anna, Scilimati, Antonio

    مصطلحات موضوعية: Fluorine, Active principle ingredients (APIs), 18F- in radio-pharmaceuticals

    Relation: ispartofbook:Fluorinated Pharmaceuticals: Advances in Medicinal Chemistry; firstpage:126; lastpage:139; numberofpages:14; http://hdl.handle.net/11586/169692; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84953786182

    الاتاحة: http://hdl.handle.net/11586/169692
    https://doi.org/10.2217/9781909453968.FSEB2013.13.113
    http://www.futuremedicine.com/doi/book/10.4155/9781909453968

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  7. 7
    Academic Journal
    Selective cyclooxygenase-1 inhibition by p6 and gastrotoxicity: preliminary investigation

    المؤلفون: Perrone, Maria Grazia, LOFRUMENTO, Dario Domenico, Vitale, Paola, DE NUCCIO, FRANCESCO, LA PESA, VELIA, Panella, Andrea, Calvello, Rosa, Cianciulli, Antonia, Panaro, Maria Antonietta, Scilimati, Antonio

    المساهمون: Perrone, Maria Grazia, Lofrumento, Dario Domenico, Vitale, Paola, DE NUCCIO, Francesco, LA PESA, Velia, Panella, Andrea, Calvello, Rosa, Cianciulli, Antonia, Panaro, Maria Antonietta, Scilimati, Antonio

    مصطلحات موضوعية: COX-1 inhibition, Gastric damage, 3-(5-Chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6)

    وصف الملف: STAMPA

    Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000351378300003; volume:95; firstpage:22; lastpage:28; numberofpages:7; journal:PHARMACOLOGY; http://hdl.handle.net/11587/394280; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84921326394

    الاتاحة: http://hdl.handle.net/11587/394280
    https://doi.org/10.1159/000369826

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  8. 8
    Academic Journal
    PET radiotracer [18F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: Preliminary investigation

    المؤلفون: PERRONE, MARIA GRAZIA, MALERBA, PAOLA, VITALE, PAOLA, PANELLA, ANDREA, SCILIMATI, Antonio, Uddin, M.d. J., Crews, B. B., Daniel, C. K., Ghebreselasie, K., Nickels, M., Tantawy, M. N., Manning, H. C., Marnett, L. J.

    المساهمون: Perrone, MARIA GRAZIA, Malerba, Paola, Uddin, M. d. J., Vitale, Paola, Panella, Andrea, Crews, B. B., Daniel, C. K., Ghebreselasie, K., Nickels, M., Tantawy, M. N., Manning, H. C., Marnett, L. J., Scilimati, Antonio

    مصطلحات موضوعية: Biomarker, Cyclooxygenase (COX)-1, Ovarian cancer, OVCAR-3 cell, PET-CT imaging

    Relation: info:eu-repo/semantics/altIdentifier/pmid/24832612; info:eu-repo/semantics/altIdentifier/wos/WOS:000337985400048; volume:80; firstpage:562; lastpage:568; numberofpages:7; journal:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY; http://hdl.handle.net/11586/125857; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84900565740; http://www.sciencedirect.com/science/article/pii/S0223523414004036

    الاتاحة: http://hdl.handle.net/11586/125857
    https://doi.org/10.1016/j.ejmech.2014.04.074
    http://www.sciencedirect.com/science/article/pii/S0223523414004036

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  9. 9
    Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs)

    المؤلفون: Andrea Panella, Savina Ferorelli, Paola Vitale, Maria Grazia Perrone, Marialessandra Contino, Antonio Scilimati, Antonio Lavecchia

    المساهمون: Perrone, Maria Grazia, Vitale, Paola, Panella, Andrea, Ferorelli, Savina, Contino, Marialessandra, Lavecchia, Antonio, Scilimati, Antonio

    مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, P-glycoprotein, 01 natural sciences, Biochemistry, Permeability, Decomposition analysi, Madin Darby Canine Kidney Cells, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Enzyme activator, Dogs, Isoxazole, Catalytic Domain, Drug Discovery, Animals, Humans, Structure–activity relationship, Cyclooxygenase Inhibitors, ATP Binding Cassette Transporter, Subfamily B, Member 1, General Pharmacology, Toxicology and Pharmaceutics, Pharmacology, Binding Sites, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Isoxazoles, 0104 chemical sciences, Cyclooxygenase, Enzyme Activation, Molecular Docking Simulation, 030104 developmental biology, Cyclooxygenase 2, Docking (molecular), Pharmacology, Toxicology and Pharmaceutics (all), Molecular docking, Cyclooxygenase 1, biology.protein, Molecular Medicine, Efflux, Caco-2 Cells, Selectivity

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef6c49238dc1d36933471704bbcd3f2
    http://hdl.handle.net/11588/634865

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  10. 10
    Selective cyclooxygenase-1 inhibition by p6 and gastrotoxicity: preliminary investigation

    المؤلفون: Antonio Scilimati, Francesco De Nuccio, Maria Antonietta Panaro, Maria Grazia Perrone, Dario Domenico Lofrumento, Antonia Cianciulli, Velia La Pesa, Paola Vitale, Rosa Calvello, Andrea Panella

    المساهمون: Perrone, Maria Grazia, Lofrumento, Dario Domenico, Vitale, Paola, DE NUCCIO, Francesco, LA PESA, Velia, Panella, Andrea, Calvello, Rosa, Cianciulli, Antonia, Panaro, Maria Antonietta, Scilimati, Antonio

    المصدر: Pharmacology. 95(1-2)

    مصطلحات موضوعية: Gastric gavage, Male, 3-(5-Chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6), High selectivity, Pharmacology, Dinoprostone, chemistry.chemical_compound, Mice, Western blot, Gastric glands, medicine, Animals, Cyclooxygenase Inhibitors, Gastric damage, Epithelial barrier, Aspirin, Ethanol, biology, medicine.diagnostic_test, COX-1 inhibition, Membrane Proteins, General Medicine, Salicylates, medicine.anatomical_structure, chemistry, Cyclooxygenase 2, Gastric Mucosa, biology.protein, Cyclooxygenase 1, Ethylene Glycols, Cyclooxygenase, medicine.drug

    وصف الملف: STAMPA

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b3ba0f5cf76aeab751b2f21a34682f
    https://pubmed.ncbi.nlm.nih.gov/25591798

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