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1
المؤلفون: Alexander V. Ivanov, Ilya M. Terenin, Sabina Mukba, Elena Alkalaeva, Ekaterina Shuvalova, Alexey Shuvalov, Nikita Biziaev, Nikolay Pustogarov, Tatiana Egorova
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: eRF1, eRF3, eIF4A, eukaryotic initiation factor 4A, Poly(A)-Binding Proteins, Biochemistry, Eukaryotic translation, TC, termination complex, Transcription (biology), Poly(A)-binding protein, Protein biosynthesis, Humans, Neoplastic transformation, Eukaryotic release factors, PABP, poly (A)-binding protein, Molecular Biology, Cell-Free System, PDCD4, PDCD4, programmed cell death protein, biology, Chemistry, Tumor Suppressor Proteins, RNA-Binding Proteins, translation termination, Translation (biology), postTC, posttermination complex, Cell Biology, Peptide Chain Termination, Translational, eRF1, eukaryotic release factor 1, Cell biology, eRF3a/c, eukaryotic release factor 3a/c, ribosome, RPS, ribosomal protein S, eIF4A, preTC, pretermination complex, biology.protein, Apoptosis Regulatory Proteins, RPL, ribosomal protein L, Peptide Termination Factors, Research Article
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2
المؤلفون: Rolf Hilgenfeld, Jian Lei, Yuri Kusov
المصدر: Antiviral Research
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, 3CLpro, 3C-like protease, PARP, poly(ADP-ribose) polymerase, Protein Conformation, mISG15, mouse interferon-stimulated gene 15, viruses, Glutamine, CoV, coronavirus, 3Ecto, Nsp3 ectodomain, ARTD, ADP-ribosyltransferases diphtheria toxin-like, Viral Nonstructural Proteins, medicine.disease_cause, Genome, TRS, transcriptional regulatory sequence, GST, glutathione S-transferase, MKRN, makorin ring finger protein, SUD, SARS-unique domain, USP, ubiquitin-specific protease, MERS, Middle-East respiratory syndrome, Gene duplication, Papain, MARylation, mono-ADP-ribosylation, ADRP, ADP-ribose-1″-phosphate phosphatase, Ub, ubiquitin, hISG15, human interferon-stimulated gene 15, Coronavirus, Macrodomain, Innate immunity, HVR, hypervariable region, TNF, tumor necrosis factor, PLpro, papain-like protease, NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells, virus diseases, ER, Endoplasmic Reticulum, Transmembrane protein, RCHY1, RING finger and CHY zinc-finger domain-containing protein 1, UTR, untranslated region, Ectodomain, Domain (ring theory), IL-6, Interleukin 6, PABP, poly(A)-binding protein, DMV, double-membrane vesicle, Ubl, ubiquitin-like, Structural biology, DPUP, Domain Preceding Ubl2 and PL2pro, Protein Binding, VEEV, Venezuelan equine encephalitis virus, Nucleic-acid binding domain, TGEV, transmissible gastroenteritis virus, Coronaviridae, HEV, hepatitis E virus, IBV, infectious bronchitis virus, Mac, macrodomain, DUB, deubiquitinating, Computational biology, Biology, R.M.S.D., root-mean-square deviation, Article, ADPr, ADP-ribose, 03 medical and health sciences, Structure-Activity Relationship, Protein Domains, ORF, open reading frame, Virology, Ubiquitin-like domain, medicine, Humans, Protein Interaction Domains and Motifs, IFN, interferon, Amino Acid Sequence, NTD, N-terminal domain, SARS, severe acute respiratory syndrome, Nsp, non-structural protein, MHV, mouse hepatitis virus, HKU, Hong Kong University, Pharmacology, 030102 biochemistry & molecular biology, Ubiquitin, CM, convoluted membrane, CHIKV, Chikungunya virus, PARylation, poly-ADP-ribosylation, MDM2, mouse double minute 2 homolog, Hypervariable region, Papain-like protease, NAB, nucleic-acid binding domain, βSM, betacoronavirus-specific marker, Mpro, main protease, 030104 developmental biology, HCoV, human coronavirus, Transcription preinitiation complex, RTC, replication/transcription complex, RID, Ras-interacting domain, IRF, interferon regulatory factor, N, nucleocapsid, TM, transmembrane
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3
المصدر: Virus Research, 234, 58-73
Virus Researchمصطلحات موضوعية: 0301 basic medicine, Enzyme complex, Cancer Research, Processivity factors, Transcription, Genetic, Arterivirus, viruses, CoV, coronavirus, Nidovirales, Virus Replication, medicine.disease_cause, PEDV, porcine epidemic diarrhea virus, chemistry.chemical_compound, Y2H, yeast 2-hybrid, TRS, transcription-regulatory sequence, RNA polymerase, ExoN, exoribonuclease, IVRA, in vitro RNA synthesis assay, Polymerase, Coronavirus, Subgenomic mRNA, Replication and transcription complex, Genetics, biology, RTC, replication and transcription complex, AV, arterivirus, DNA-Directed RNA Polymerases, Subgenomic mRNA synthesis, Infectious Diseases, 5-AZC, 5-azacytidine, RNA, Viral, Polymerase fidelity, HCoV-229E, human coronavirus 229E, Exoribonuclease activity, kb, kilobases, wt, wild-type, RBV, ribavirin, TGEV, transmissible gastroenteritis virus, PNS, post-nuclear supernatant, M2H, mammalian 2-hybrid, RNA-dependent RNA polymerase, NiRAN, nidovirus RdRp-associated nucleotidyltransferase, EAV, equine arteritis virus, IMPDH, inosine-5′-monophosphate dehydrogenase, Article, ZBD, zinc-binding domain, RdRp, RNA dependent RNA polymerase, 03 medical and health sciences, ORF, open reading frame, Virology, MHV, murine hepatitis coronavirus, medicine, Animals, Humans, CBV3, coxsackievirus B3, nsp, non-structural protein, ub, ubiquitin, SARS, severe acute resporiatory syndrome, EM, electron microscopy, pp, polyprotein, FCoV, feline coronavirus, MERS, Middle East respiratory syndrome, sg, subgenomic, RNA, PABP, Poly(A)-binding protein, PRRSV, porcine reproductive and respiratory syndrome virus, 030104 developmental biology, chemistry, ss, single-stranded, FMDV, foot and mouth disease virus, biology.protein, 5-FU, 5-fluorouracil, Protein Multimerization
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4
المؤلفون: A. Friedrich, Michele Solimena, Suchita Nath-Sain, Anke Sönmez, Klaus-Peter Knoch, C. Wegbrod, Antje Petzold, Mike Beck, Carla Münster, Merja Roivainen, Hendryk Schneider
المصدر: Molecular Metabolism
مصطلحات موضوعية: Translation, EV, Enterovirus, medicine.medical_treatment, IRES, internal ribosomal entry site, ITAF, IRES-trans-acting factor, Prohormone convertase, RNA-binding protein, mTORC1, Polypyrimidine tract-binding protein, Biology, PC, prohormone convertase, ER, endoplasmic reticulum, eIF4E-V5, eIF4E tagged at its C-terminus with a V5-epitope, F, Faulkner, Poly(A)-binding protein, medicine, Insulin, CV, Coxsackievirus, mTORC1, mammalian Target Of Rapamycin Complex 1, Molecular Biology, Diabetes, Granule (cell biology), Beta cells, MCA, MIN6 cell adapted, Cell Biology, Molecular biology, Virus, PTBP1, polypyrimidine tract-binding protein 1, Cell biology, UTR, untranslated region, Internal ribosome entry site, S6K1, p70S6 Kinase 1, Secretory granules, biology.protein, PABP, poly(A)-binding protein, Original Article, T1D, type 1 diabetes, Beta cell, FL, firefly luciferase
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5
المؤلفون: James P. Reddington, Lora McCracken, Nicholas A. Morrice, Matthew Brook, Zhi-Liang Lu, Nicola K. Gray
المصدر: Brook, M, McCracken, L, Reddington, J P, Lu, Z-L, Morrice, N A & Gray, N K 2012, ' The multifunctional poly(A)-binding protein (PABP) 1 is subject to extensive dynamic post-translational modification, which molecular modelling suggests plays an important role in co-ordinating its activities ', Biochemical Journal, vol. 441, no. 3, pp. 803-812 . https://doi.org/10.1042/BJ20111474
Biochemical Journalمصطلحات موضوعية: Models, Molecular, eRF3-N, N-terminal eRF3, PTM, post-translational modification, mRNA translation, PRMT, protein arginine N-methyltransferase, RNA-binding protein, Lysine, TOB, transducer of ERBB2, eIF, eukaryotic initiation factor, Poly(A)-Binding Protein I, Biochemistry, Mice, miRNA, microRNA, MS/MS, tandem MS, Poly(A)-binding protein, TSA, trichostatin A, Tissue Distribution, MLLE, methionine-leucine-leucine-glutamate motif-containing domain, Cells, Cultured, G3BP, Ras GAP (GTPase-activating protein) SH3 (Src homology 3) domain-binding protein, AdOX, adenosine dialdehyde, HRP, horseradish peroxidase, Methylation, poly(A)-binding protein (PABP), GAPDH, glyceraldehyde-3-phosphate dehydrogenase, PABP, poly(A)-binding protein, DTT, dithiothrietol, poly(A)-binding-protein-interacting motif 2 (PAM2)–poly(A)binding protein C-terminal domain (PABC) interaction, eRF, eukaryotic release factor, PAM, PABP-interacting motif, Research Article, PCNA, proliferating cell nuclear antigen, PAN, poly(A) nuclease, Biology, Arginine, Structure-Activity Relationship, PABC, poly(A)-binding protein 1 C-terminal domain, Animals, Humans, TD-NEM, transcription-dependent nuclear export motif, Protein Methyltransferases, Binding site, Molecular Biology, Messenger RNA, RNA, Cell Biology, SG, stress granule, MEF, mouse embryonic fibroblast, PAIP, poly(A)-interacting protein, Messenger RNP, Kinetics, RRM, RNA recognition motif, posttranscriptional control, post-translational modification, Acetylation, biology.protein, eEF, eukaryotic elongation factor, Protein Processing, Post-Translational, posttranscriptional control, post-translational modification, HeLa Cells
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6
المصدر: Biochemical Journal
مصطلحات موضوعية: RNA Caps, Ars2, arsenite-resistance protein 2, TMG, 2,2,7-trimethylguanosine cap, ABA, abscisic acid, Cbp, cap-binding protein, translation, Cdk9, cyclin-dependent kinase 9, Review Article, TREX, transcription export complex, eIF, eukaryotic initiation factor, splicing, SRSF1, serine/arginine-rich splicing factor 1, parasitic diseases, Animals, Humans, CBC, cap-binding complex, PARN, poly(A)-specific ribonuclease, RNA, Messenger, NELF, negative elongation factor, RAM, RNMT-activating mini-protein, Nuclear Cap-Binding Protein Complex, Guanosine, cap-binding complex (CBC), NMD, nonsense-mediated decay, MIF4G, middle domain of eIF4G, snRNP, small nuclear ribonucleoprotein, 7-methylguanosine cap (7mG), mTORC1, mammalian target of rapamycin complex 1, PHAX, phosphorylated adaptor of RNA export, PTC, premature termination codon, 7mG, 7-methylguanosine cap, RRM, RNA-recognition motif, CTD, C-terminal domain, RNA pol II, RNA polymerase II, Gene Expression Regulation, CF IA, cleavage factor IA, RNA Cap-Binding Proteins, hnRNP, heterogeneous nuclear ribonucleoprotein, PABP, poly(A)-binding protein, mRNP, messenger ribonucleoprotein, transcription, CTIF, CBC-dependent translation initiation factor, DSIF, DRB sensitivity-inducing factor, Signal Transduction, P-TEFb, positive transcription elongation factor b, RNMT, RNA (guanine-7-)methyltransferase
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7
المؤلفون: Alexander M. J. Rattray, Pamela Nicholson, Berndt Müller
المصدر: Bioscience Reports
Bioscience Reports, Vol 33, Iss 5, p e00066 (2013)مصطلحات موضوعية: Protein isoform, Untranslated region, mRNA translation, lcsh:Life, lcsh:QR1-502, RNA-binding protein, eIF, eukaryotic initiation factor, Biochemistry, lcsh:Microbiology, PAIP1, polyadenylate-binding protein-interacting protein 1, Histones, Protein Isoforms, Translation factor, CBP80/20, cap-binding protein 80/20, Conserved Sequence, GFP, green fluorescent protein, Regulation of gene expression, SLBP, 0303 health sciences, CTIF, CBP80/20-dependent translation initiation factor, snRNP, small nuclear ribonucleoprotein, 030302 biochemistry & molecular biology, Nuclear Proteins, kb, kilobase, Protein Transport, Histone, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, SLIP1, SLBP interacting protein 1, checkpoints, HBP, hairpin-binding protein, DNA Replication, nt, nucleotide, histone gene expression, Molecular Sequence Data, cellular localization, Biophysics, Biology, ATM, ataxia telangiectasia mutated- and Rad3-related, 03 medical and health sciences, alternative splicing, ORF, open reading frame, Stress, Physiological, Caffeine, Humans, Amino Acid Sequence, RNA, Messenger, Molecular Biology, 030304 developmental biology, mRNA Cleavage and Polyadenylation Factors, Original Paper, QPCR, quantitative PCR, PABP, poly(A) binding protein, RBD, RNA-binding domain, Alternative splicing, Cell Biology, Molecular biology, bp, base pairs, lcsh:QH501-531, Gene Expression Regulation, SLBP, stem-loop binding protein, biology.protein, MIF1GD, MIF4G domain, HU, hydroxyurea, HeLa Cells, DAPI, 4′,6-diamidino-2-phenylindole
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المؤلفون: Matthew Brook, Nicola K. Gray
المصدر: Brook, M & Gray, N K 2012, ' The role of mammalian poly(A)-binding proteins in co-ordinating mRNA turnover ', Biochemical Society Transactions, vol. 40, no. 4, pp. 856-64 . https://doi.org/10.1042/BST20120100
Biochemical Society Transactionsمصطلحات موضوعية: nonsense-mediated decay, PTM, post-translational modification, EJC, exon-junction complex, UPF, up-frameshift, CAF1, CCR4-associated factor 1, eIF, eukaryotic initiation factor, Biochemistry, microRNA (miRNA), mRNA decay, Poly(A)-binding protein, miRNA, microRNA, RISC, RNA-induced silencing complex, mCRD, major coding-region determinant, ErEN, erythroid-cell-specific endonuclease, 0303 health sciences, biology, AUBP, ARE-binding protein, NMD, nonsense-mediated decay, PAM2, PABP-interacting motif 2, TTP, tristetraprolin, 030302 biochemistry & molecular biology, UNR, upstream of N-ras, PTC, premature termination codon, deadenylation, mRNA surveillance, Cell biology, translation factor, UTR, untranslated region, XRN1, exoribonuclease 1, PABP, poly(A)-binding protein, PABC, PABP C-terminal domain, NSAP1, NS1-associated protein 1, DCP, decapping protein, TOB, transducer of ErbB2, eRF, eukaryotic release factor, LSm, like-Sm, S1, cytoplasmic poly(A)-binding protein (PABP), CCR4, carbon catabolite repressor protein 4, PAN, poly(A) nuclease, NOT, negative on TATA, Poly(A)-Binding Proteins, 03 medical and health sciences, NF-L, neurofilament light, AUF1, adenine/uridine-rich RNA-binding factor 1, microRNA, P-bodies, Animals, PARN, poly(A)-specific ribonuclease, PAIP1, PABP-interacting protein 1, TNRC6, trinucleotide repeat-containing 6, RNA, Messenger, 030304 developmental biology, ARE, adenine/uridine-rich element, Independent Meeting, Messenger RNA, RNA, RRM, RNA-recognition motif, Messenger RNP, MicroRNAs, biology.protein, ePAPB, embryonic PABP, Function (biology), CRE, cytosine-rich element
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9Academic Journal
المؤلفون: Boyer, Bert B.
المساهمون: ALASKA UNIV FAIRBANKS INST OF ARCTIC BIOLOGY AND MUSEUM
المصدر: DTIC AND NTIS
مصطلحات موضوعية: Biochemistry, Biology, Ecology, METABOLISM, HIBERNATION, SQUIRRELS, PROTEINS, PROTONS, RESPIRATION, MOLECULAR PROPERTIES, RIBONUCLEIC ACIDS, SUPPRESSION, BIOSYNTHESIS, MITOCHONDRIA, PABP(POLY A BINDING PROTEIN)
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