المؤلفون: James P. Bauer, Sarah L. Rader, Max E. Joffe, Wooseok Kwon, Juliana Quay, Leann Seanez, Chengwen Zhou, P. Jeffrey Conn, Alan S. Lewis

المصدر: Biological Psychiatry Global Open Science, Vol 1, Iss 2, Pp 101-111 (2021)

مصطلحات موضوعية: Hippocampus, Hyperactivity, Learning and memory, Mossy cells, Psychosis, Schizophrenia, Psychiatry, RC435-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2667174321000112; https://doaj.org/toc/2667-1743

URL الوصول: https://doaj.org/article/8a9ca9a844ee44ec836d967e7a3b4137

المؤلفون: James Maksymetz, Nellie E. Byun, Deborah J. Luessen, Brianna Li, Robert L. Barry, John C. Gore, Colleen M. Niswender, Craig W. Lindsley, Max E. Joffe, P. Jeffrey Conn

المصدر: Cell Reports, Vol 37, Iss 5, Pp 109950- (2021)

مصطلحات موضوعية: metabotropic glutamate receptor, mGlu1, prefrontal cortex, inhibitory transmission, somatostatin interneurons, excitation-inhibition balance, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124721014273; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/a075ccbe92734d68bafa119211f41b75

المؤلفون: Christopher C. Presley, Charles K. Perry, Elizabeth S. Childress, Matthew J. Mulder, Vincent B. Luscombe, Alice L. Rodriguez, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley

المصدر: ACS Omega, Vol 4, Iss 7, Pp 12782-12789 (2019)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2470-1343

URL الوصول: https://doaj.org/article/5fdf499332094c6c9828c3faab3a798f

المؤلفون: Nicole M. Fisher, Aqeela AlHashim, Aditi B. Buch, Hana Badivuku, Manar M. Samman, Kelly M. Weiss, Gabriela I. Cestero, Mark D. Does, Jerri M. Rook, Craig W. Lindsley, P. Jeffrey Conn, Rocco G. Gogliotti, Colleen M. Niswender

المصدر: JCI Insight, Vol 6, Iss 4 (2021)

مصطلحات موضوعية: Neuroscience, Medicine

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2379-3708

URL الوصول: https://doaj.org/article/a777c073552d4febb04f18fa5a845f7b

المؤلفون: Mark S. Moehle (11217998), Aaron M. Bender (5155397), Jonathan W. Dickerson (3628004), Daniel J. Foster (4760043), Aidong Qi (2204728), Hyekyung P. Cho (59088), Yuping Donsante (11218001), Weimin Peng (2649190), Zoey Bryant (11218004), Kaylee J. Stillwell (11218007), Thomas M. Bridges (1336731), Sichen Chang (1475053), Katherine J. Watson (11218010), Jordan C. O’Neill (3778144), Julie L. Engers (1475044), Li Peng (83452), Alice L. Rodriguez (1270236), Colleen M. Niswender (353419), Craig W. Lindsley (203380), Ellen J. Hess (11218013), P. Jeffrey Conn (1270239), Jerri M. Rook (1315593)

مصطلحات موضوعية: Biochemistry, Medicine, Genetics, Molecular Biology, Neuroscience, Pharmacology, Evolutionary Biology, Cancer, Science Policy, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, nonselective mAChR antagonists, mAChR knockout animals, M 4 receptor activation, subtype, movement disorders, nonselective antimuscarinic therape., muscarinic acetylcholine receptors, M 4 Muscarinic Acetylcholine Recept., M 4, antiparkinsonian, M 4 muscarinic acetylcholine receptor, role, VU, antidystonic efficacy, Antidystonic Efficacy Nonselective ., model

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_the_First_Selective_M_sub_4_sub_Muscarinic_Acetylcholine_Receptor_Antagonists_with_i_in_Vivo_i_Antiparkinsonian_and_Antidystonic_Efficacy/15091304

الاتاحة: https://doi.org/10.1021/acsptsci.0c00162.s001

المؤلفون: Matthew Spock (11219123), Trever R. Carter (11219126), Katrina A. Bollinger (4375849), Changho Han (1309563), Logan A. Baker (11219129), Alice L. Rodriguez (1270236), Li Peng (83452), Jonathan W. Dickerson (3628004), Aidong Qi (2204728), Jerri M. Rook (1315593), Jordan C. O’Neill (3778144), Katherine J. Watson (11218010), Sichen Chang (1475053), Thomas M. Bridges (1336731), Julie L. Engers (1475044), Darren W. Engers (655505), Colleen M. Niswender (353419), P. Jeffrey Conn (1270239), Craig W. Lindsley (203380), Aaron M. Bender (5155397)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Pharmacology, Evolutionary Biology, Sociology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, novel use, DMPK properties, movement disorders, Orally Bioavailable M 4 Muscarinic ., CYP inhibition, deuterium incorporation, SAR, M 4 mAChR antagonist, VU 6028418

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_VU6028418_A_Highly_Selective_and_Orally_Bioavailable_M_sub_4_sub_Muscarinic_Acetylcholine_Receptor_Antagonist/15094160

الاتاحة: https://doi.org/10.1021/acsmedchemlett.1c00363.s001

المؤلفون: Shigetada Nakanishi, P. Jeffrey Conn, Robert M. Duvoisin, James A. Monn, Michihiro Tateyama, Ferdinando Nicoletti, Francine Acher, Philippe Rondard, Francesco Ferraguti, Colleen M. Niswender, Yoshihiro Kubo, Karen J. Gregory, Giuseppe Battaglia, Cyril Goudet, Hans Bräuner-Osborne, David R. Hampson, Peter J. Flor, Ryuichi Shigemoto, Jean-Philippe Pin, Darryle D. Schoepp, Michael P. Johnson

مصطلحات موضوعية: Aurora Universities Network

Relation: url:https://www.openaccessrepository.it/communities/itmirror; https://www.openaccessrepository.it/record/117103

الاتاحة: https://www.openaccessrepository.it/record/117103
https://doi.org/10.2218/gtopdb/f40/2021.3

المؤلفون: Eric J. Nunes, Nardos Kebede, Joshua L. Haight, Daniel J. Foster, Craig W. Lindsley, P. Jeffrey Conn, Nii A. Addy

المصدر: Journal of Pharmacology and Experimental Therapeutics. 385:146-156

مصطلحات موضوعية: Pharmacology, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fe569bf04c5f6ef87ac9130cb2982d7c
https://doi.org/10.1124/jpet.122.001438

المؤلفون: James Maksymetz, Sean P. Moran, P. Jeffrey Conn

المصدر: Molecular Brain, Vol 10, Iss 1, Pp 1-19 (2017)

مصطلحات موضوعية: mGlu receptor, Schizophrenia, Allosteric modulator, Signal bias, Heterodimer, PAM, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13041-017-0293-z; https://doaj.org/toc/1756-6606

URL الوصول: https://doaj.org/article/4a1b8eaa1f5846ef86557a168d221c08

المؤلفون: Deborah J, Luessen, P Jeffrey, Conn

المصدر: Pharmacological Reviews. 74:630-661

مصطلحات موضوعية: Pharmacology, Brain Diseases, Binding Sites, Allosteric Regulation, Glutamic Acid, Humans, Molecular Medicine, Receptors, Metabotropic Glutamate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0616a4eb964885b70c77db0e3dd86bc
https://doi.org/10.1124/pharmrev.121.000540

المؤلفون: Deborah Luessen, Isabel Gallinger, Brenna Wolfe, P. Jeffrey Conn

المصدر: ASPET 2023 Annual Meeting Abstract - Central Nervous System Pharmacology - Neuropharmacology.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d26b4f4590ada3393b9de4779e9af1c5
https://doi.org/10.1124/jpet.122.138580

المؤلفون: Shalini Dogra, P. Jeffrey Conn

المصدر: ASPET 2023 Annual Meeting Abstract - Central Nervous System Pharmacology - Neuropharmacology.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::830e7d04b23906f41001728fe98841e5
https://doi.org/10.1124/jpet.122.195740

المؤلفون: Jerri Rook, Zixiu Xiang, Jonathan Dickerson, Shalini Dogra, Kendall Jensen, Insung Kim, Megan Ohler, Kelly Weiss, P. Jeffrey Conn

المصدر: ASPET 2023 Annual Meeting Abstract - Central Nervous System Pharmacology - Behavioral.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5c500f4aeea526375bc0949b7c50816d
https://doi.org/10.1124/jpet.122.253010

المؤلفون: Michihiro Tateyama, Ryuichi Shigemoto, Darryle D. Schoepp, Philippe Rondard, Jean-Philippe Pin, Colleen Niswender, Ferdinando Nicoletti, Shigetada Nakanishi, James Monn, Yoshihiro Kubo, Michael P. Johnson, David Hampson, Karen J. Gregory, Cyril Goudet, Peter J. Flor, Francesco Ferraguti, Robert Duvoisin, P. Jeffrey Conn, Hans Bräuner-Osborne, Giuseppe Battaglia, Francine Acher

المصدر: IUPHAR/BPS Guide to Pharmacology CITE. 2023

مصطلحات موضوعية: General Medicine, General Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5c9e1754e32c6abf6b867579896219f9
https://doi.org/10.2218/gtopdb/f40/2023.1

المؤلفون: Daniel Foster, Samantha Yohn, Muhammad Mahmood, Madigan Lavery, Daniel O’Brien, Weimin Peng, P. Jeffrey Conn

المصدر: Journal of Clinical and Translational Science, Vol 3, Pp 19-20 (2019)

مصطلحات موضوعية: Medicine

Relation: https://www.cambridge.org/core/product/identifier/S2059866119000487/type/journal_article; https://doaj.org/toc/2059-8661; https://doaj.org/article/84675a00cb444714bc1fb1821fff7966

الاتاحة: https://doi.org/10.1017/cts.2019.48
https://doaj.org/article/84675a00cb444714bc1fb1821fff7966

المؤلفون: Ferdinando Nicoletti, Luisa Di Menna, Luisa Iacovelli, Rosamaria Orlando, Anna Rita Zuena, P. Jeffrey Conn, Shalini Dogra, Max E. Joffe

المساهمون: Nicoletti, Ferdinando, DI MENNA, Luisa, Iacovelli, Luisa, Orlando, Rosamaria, Zuena, Anna Rita, Jeffrey Conn, P., Dogra, Shalini, Joffe, Max E.

مصطلحات موضوعية: Metabotropic glutamate receptor, GPCR, Receptor-receptor interaction, CNS disorder, Therapeutic targets

Relation: info:eu-repo/semantics/altIdentifier/pmid/37142158; info:eu-repo/semantics/altIdentifier/wos/WOS:000999179400001; volume:235; firstpage:1; lastpage:11; numberofpages:11; journal:NEUROPHARMACOLOGY; https://hdl.handle.net/11573/1680850

الاتاحة: https://hdl.handle.net/11573/1680850
https://doi.org/10.1016/j.neuropharm.2023.109569

المؤلفون: Rocco G. Gogliotti, Weilun Qian, Ferdinando Nicoletti, Max E. Joffe, P. Jeffrey Conn, Shalini Dogra, Colleen M. Niswender, Branden J. Stansley, Craig W. Lindsley, Zixiu Xiang

المصدر: Biological Psychiatry. 90:385-398

مصطلحات موضوعية: 0301 basic medicine, Receptor expression, Hippocampus, Long-term potentiation, Cognition, mGlu, 3, 5, Schizophrenia, Synaptic plasticity, Biology, Associative learning, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Metabotropic glutamate receptor, Metaplasticity, Fear conditioning, Neuroscience, 030217 neurology & neurosurgery, Biological Psychiatry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4cdb56df69d8bf35d7d940f7842fb7c
https://doi.org/10.1016/j.biopsych.2021.02.970

المؤلفون: Sichen Chang, Jonathan W. Dickerson, Baker Logan A, Thomas M. Bridges, Craig W. Lindsley, Darren W. Engers, Aidong Qi, Jerri M. Rook, Aaron M. Bender, P. Jeffrey Conn, Katrina A. Bollinger, Colleen M. Niswender, Changho Han, Alice L. Rodriguez, Trever R Carter, Li Peng, Julie L. Engers, Jordan C. O’Neill, Matthew Spock, Katherine J. Watson

المصدر: ACS Med Chem Lett

مصطلحات موضوعية: Dystonia, Movement disorders, Chemistry, Organic Chemistry, Antagonist, Pharmacology, medicine.disease, Highly selective, Biochemistry, In vitro, Bioavailability, In vivo, Drug Discovery, Muscarinic acetylcholine receptor, medicine, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388290e5061b99e6a85f95357b9a3b32
https://doi.org/10.1021/acsmedchemlett.1c00363

المؤلفون: Jerri M. Rook, Aaron M. Bender, Colleen M. Niswender, Yuping Donsante, P. Jeffrey Conn, Hyekyung P. Cho, Li Peng, Julie L. Engers, Jonathan W. Dickerson, Thomas M. Bridges, Craig W. Lindsley, Ellen J. Hess, Sichen Chang, Aidong Qi, Weimin Peng, Mark S. Moehle, Jordan C. O’Neill, Daniel J. Foster, Alice L. Rodriguez, Zoey Bryant, Katherine J. Watson, Kaylee J. Stillwell

المصدر: ACS Pharmacology & Translational Science. 4:1306-1321

مصطلحات موضوعية: Pharmacology, Dystonia, Movement disorders, business.industry, Central nervous system, medicine.disease, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Tolerability, In vivo, Muscarinic acetylcholine receptor, Genetic model, Medicine, Pharmacology (medical), medicine.symptom, business, Neurotransmitter

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f5425dfe0a6fb74da410878130ec6660
https://doi.org/10.1021/acsptsci.0c00162

المؤلفون: Juliana Quay, Chengwen Zhou, P. Jeffrey Conn, Alan S. Lewis, Sarah L. Rader, Max E. Joffe, Wooseok Kwon, James P. Bauer, Leann Seanez

المصدر: Biological Psychiatry Global Open Science, Vol 1, Iss 2, Pp 101-111 (2021)
Biol Psychiatry Glob Open Sci

مصطلحات موضوعية: Psychosis, RC435-571, Hippocampus, Stimulation, Hippocampal formation, Biology, Inhibitory postsynaptic potential, behavioral disciplines and activities, Article, Learning and memory, Mossy cells, medicine, Psychiatry, Long axis, Hyperactivation, Dentate gyrus, Cognition, General Medicine, medicine.disease, Hyperactivity, Schizophrenia, Excitatory postsynaptic potential, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0a4f078d447ba795e1d9330842259a
http://www.sciencedirect.com/science/article/pii/S2667174321000112