المؤلفون: Hoorens, Mark W H, Ourailidou, Maria E, Rodat, Theo, van der Wouden, Petra E, Kobauri, Piermichele, Kriegs, Malte, Peifer, Christian, Feringa, Ben L, Dekker, Frank J, Szymanski, Wiktor

المصدر: Hoorens , M W H , Ourailidou , M E , Rodat , T , van der Wouden , P E , Kobauri , P , Kriegs , M , Peifer , C , Feringa , B L , Dekker , F J & Szymanski , W 2019 , ' Light-controlled inhibition of BRAFV600E kinase ' , European Journal of Medicinal Chemistry , vol. 179 , pp. 133-146 . https://doi.org/10.1016/j.ejmech.2019.06.042

وصف الملف: application/pdf

Relation: https://research.rug.nl/en/publications/1bd86909-6a22-4ae1-9a57-bc0627eb5423

الاتاحة: https://hdl.handle.net/11370/1bd86909-6a22-4ae1-9a57-bc0627eb5423
https://research.rug.nl/en/publications/1bd86909-6a22-4ae1-9a57-bc0627eb5423
https://doi.org/10.1016/j.ejmech.2019.06.042
https://pure.rug.nl/ws/files/108335304/MANUSCRIPT_BRAFV600E_small_corrections.pdf

المؤلفون: Leus, Niek G. J., van den Bosch, Thea, van der Wouden, Petra E., Krist, Kim, Ourailidou, Maria E., Eleftheriadis, Nikolaos, Kistemaker, Loes E. M., Bos, Sophie, Gjaltema, Rutger A. F., Mekonnen, Solomon A., Bischoff, Rainer, Gosens, Reinoud, Haisma, Hidde J., Dekker, Frank J.

المصدر: Leus , N G J , van den Bosch , T , van der Wouden , P E , Krist , K , Ourailidou , M E , Eleftheriadis , N , Kistemaker , L E M , Bos , S , Gjaltema , R A F , Mekonnen , S A , Bischoff , R , Gosens , R , Haisma , H J & Dekker , F J 2017 , ' HDAC1-3 inhibitor MS-275 enhances IL10 expression in RAW264.7 macrophages and reduces cigarette smoke-induced airway inflammation in mice ' , Scientific Reports , vol. 7 , 45047 ....

مصطلحات موضوعية: OBSTRUCTIVE PULMONARY-DISEASE, NF-KAPPA-B, HISTONE DEACETYLASE INHIBITORS, CUT LUNG SLICES, GENE-EXPRESSION, ANTIINFLAMMATORY PROPERTIES, INHALED CORTICOSTEROIDS, MEDIATED INFLAMMATION, IN-VITRO, EX-VIVO

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/98ac80e5-497a-44a4-b9d5-539fa7e99b48
https://research.rug.nl/en/publications/98ac80e5-497a-44a4-b9d5-539fa7e99b48
https://doi.org/10.1038/srep45047
https://pure.rug.nl/ws/files/49813465/srep45047.pdf

المؤلفون: Ourailidou, Maria E., Lenoci, Alessia, Zwergel, Clemens, Rotili, Dante, Mai, Antonello, Dekker, Frank J

المصدر: Ourailidou , M E , Lenoci , A , Zwergel , C , Rotili , D , Mai , A & Dekker , F J 2017 , ' Towards the development of activity-based probes for detection of lysine-specific demethylase-1 activity ' , Bioorganic & Medicinal Chemistry , vol. 25 , no. 3 , pp. 847-856 . https://doi.org/10.1016/j.bmc.2016.11.043

مصطلحات موضوعية: Lysine demethylation, Tumorigenesis, Tranylcypromine, Irreversible inhibition, Enzyme labeling, LSD1 HISTONE DEMETHYLASE, OXIDATIVE HECK REACTION, THERAPEUTIC STRATEGY, BIOLOGICAL-ACTIVITY, STRUCTURAL BASIS, HDAC INHIBITORS, BREAST-CANCER, PROTEIN, CELLS, DERIVATIVES

وصف الملف: application/pdf

Relation: https://research.rug.nl/en/publications/15be3b25-f97c-4db5-be88-154df672f96d

الاتاحة: https://hdl.handle.net/11370/15be3b25-f97c-4db5-be88-154df672f96d
https://research.rug.nl/en/publications/15be3b25-f97c-4db5-be88-154df672f96d
https://doi.org/10.1016/j.bmc.2016.11.043
https://pure.rug.nl/ws/files/40292347/1_s2.0_S0968089616312640_main.pdf

المؤلفون: Leus, Niek G J, van der Wouden, Petra E, van den Bosch, Thea, Hooghiemstra, Wouter T R, Ourailidou, Maria E, Kistemaker, Loes E M, Bischoff, Rainer, Gosens, Reinoud, Haisma, Hidde J, Dekker, Frank J

المصدر: Leus , N G J , van der Wouden , P E , van den Bosch , T , Hooghiemstra , W T R , Ourailidou , M E , Kistemaker , L E M , Bischoff , R , Gosens , R , Haisma , H J & Dekker , F J 2016 , ' HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity ' , Biochemical Pharmacology , pp. 58-74 . https://doi.org/10.1016/j.bcp.2016.03.010

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/8ee042be-6dfb-4600-91d1-adb2a6c6029d
https://research.rug.nl/en/publications/8ee042be-6dfb-4600-91d1-adb2a6c6029d
https://doi.org/10.1016/j.bcp.2016.03.010
https://pure.rug.nl/ws/files/34214048/Leus_et_al._Biochem_Pharmacol_2016.pdf

المؤلفون: Ourailidou, Maria E., Leus, Niek G. J., Krist, Kim, Lenoci, Alessia, Mai, Antonello, Dekker, Frank J.

المصدر: Ourailidou , M E , Leus , N G J , Krist , K , Lenoci , A , Mai , A & Dekker , F J 2016 , ' Chemical epigenetics to assess the role of HDAC1-3 inhibition in macrophage pro-inflammatory gene expression ' , MedChemCommun , vol. 7 , no. 11 , pp. 2184-2190 . https://doi.org/10.1039/c6md00375c

مصطلحات موضوعية: HISTONE DEACETYLASE INHIBITORS, NF-KAPPA-B, ACETYLATION, CANCER, DISEASES, ACETYLTRANSFERASES, TRANSCRIPTION, SELECTIVITY, ACTIVATION, ENTINOSTAT

وصف الملف: application/pdf

Relation: https://research.rug.nl/en/publications/352fc68e-7ae3-4a20-9045-b16807215054

الاتاحة: https://hdl.handle.net/11370/352fc68e-7ae3-4a20-9045-b16807215054
https://research.rug.nl/en/publications/352fc68e-7ae3-4a20-9045-b16807215054
https://doi.org/10.1039/c6md00375c
https://pure.rug.nl/ws/files/39193390/Chemical_epigenetics_to_assess_the_role_of_HDAC1_3.pdf

المؤلفون: Ourailidou, Maria E., Zwinderman, Martijn R.H., Dekker, Frans

المصدر: Ourailidou , M E , Zwinderman , M R H & Dekker , F 2016 , ' Bioorthogonal metabolic labelling with acyl-CoA reporters : targeting protein acylation ' , MedChemCommun , vol. 7 , no. 3 , pp. 399-408 . https://doi.org/10.1039/c5md00446b

مصطلحات موضوعية: CYTOSOLIC ACETYL-COENZYME, OXIDATIVE HECK REACTION, 1,3-DIPOLAR CYCLOADDITION REACTION, ATP-CITRATE LYASE, CHEMICAL REPORTERS, CLICK CHEMISTRY, FATTY-ACIDS, POSTTRANSLATIONAL MODIFICATIONS, TERMINAL ALKYNES, HISTONE ACETYLTRANSFERASES

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/671f098c-a150-4320-8fef-b019b69a0920
https://research.rug.nl/en/publications/671f098c-a150-4320-8fef-b019b69a0920
https://doi.org/10.1039/c5md00446b
https://pure.rug.nl/ws/files/31710797/published_review.pdf

المؤلفون: Szymanski, Wiktor, Ourailidou, Maria E., Velema, Willem A., Dekker, Frank J., Feringa, Ben L.

المصدر: Szymanski , W , Ourailidou , M E , Velema , W A , Dekker , F J & Feringa , B L 2015 , ' Light-Controlled Histone Deacetylase (HDAC) Inhibitors : Towards Photopharmacological Chemotherapy ' , Chemistry , vol. 21 , no. 46 , pp. 16517-16524 . https://doi.org/10.1002/chem.201502809

مصطلحات موضوعية: cancer, cytotoxicity, drug design, inhibitors, photochemistry, OPTICAL CONTROL, VISIBLE-LIGHT, AZOBENZENE PHOTOSWITCHES, ANTICANCER AGENTS, CANCER-TREATMENT, DISEASES, DRUG, ACETYLTRANSFERASES, MALIGNANCIES, DELIVERY

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/17620dbe-6f30-44ac-a3f3-fd2c0c207be6
https://research.rug.nl/en/publications/17620dbe-6f30-44ac-a3f3-fd2c0c207be6
https://doi.org/10.1002/chem.201502809
https://pure.rug.nl/ws/files/84294107/Light_Controlled_Histone_Deacetylase_HDAC_Inhibitors_Towards.pdf

المؤلفون: Ourailidou, Maria E., Dockerty, Paul, Witte, Martin, Poelarends, Gerrit J., Dekker, Frank J.

المصدر: Ourailidou , M E , Dockerty , P , Witte , M , Poelarends , G J & Dekker , F J 2015 , ' Metabolic alkene labeling and in vitro detection of histone acylation via the aqueous oxidative Heck reaction ' , Organic & Biomolecular Chemistry , vol. 13 , no. 12 , pp. 3648-3653 . https://doi.org/10.1039/c4ob02502d

وصف الملف: application/pdf

Relation: https://research.rug.nl/en/publications/ed33aec3-7a4e-41ae-97c1-f2b3168f23f5

الاتاحة: https://hdl.handle.net/11370/ed33aec3-7a4e-41ae-97c1-f2b3168f23f5
https://research.rug.nl/en/publications/ed33aec3-7a4e-41ae-97c1-f2b3168f23f5
https://doi.org/10.1039/c4ob02502d
https://pure.rug.nl/ws/files/84388657/Metabolic_alkene_labeling_and_in_vitro_detection_of_histone_acylation_via_the_aqueous.pdf

المؤلفون: Van Den Bosch, Thea, Boichenko, Alexander, Leus, Niek G. J., Ourailidou, Maria E., Wapenaar, Hannah, ROTILI, Dante, MAI, Antonello, Imhof, Axel, Bischoff, Rainer, Haisma, Hidde J., Dekker, Frank J.

المساهمون: Van Den Bosch, Thea, Boichenko, Alexander, Leus, Niek G. J., Ourailidou, Maria E., Wapenaar, Hannah, Rotili, Dante, Mai, Antonello, Imhof, Axel, Bischoff, Rainer, Haisma, Hidde J., Dekker, Frank J.

مصطلحات موضوعية: acetylation, C646, histone, inflammation, macrophage, NF-kB, amino acid sequence, animal, benzoate, cell line, dose-response relationship, drug, gene expression regulation, histone deacetylase inhibitor, histone deacetylase, inflammation mediator, lung, mice, molecular sequence data, NF-kappa B, organ culture technique, pyrazole, p300-CBP transcription factor, pharmacology, biochemistry

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000371446300011; volume:102; firstpage:130; lastpage:140; numberofpages:11; journal:BIOCHEMICAL PHARMACOLOGY; https://hdl.handle.net/11590/493101; www.elsevier.com/locate/biochempharm

الاتاحة: https://hdl.handle.net/11590/493101
https://doi.org/10.1016/j.bcp.2015.12.010

المؤلفون: Szymanski, Wiktor, Ourailidou, Maria E., Velema, Willem A., Dekker, Frank J., Feringa, Ben L.

مصطلحات موضوعية: Histone Deacetylase Inhibitors, Sulfonamides, Vorinostat, Indoles, Light, Panobinostat, Humans, Antineoplastic Agents, Apoptosis, Hydroxamic Acids, Article, Cell Proliferation, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::523a1151ca6f57f192ebbe5fede0bd90
https://europepmc.org/articles/PMC5221732/

المؤلفون: Ourailidou, Maria. E., Zwinderman, Martijn R. H., Dekker, Frank J.

المصدر: MedChemComm; Mar2016, Vol. 7 Issue 3, p399-408, 10p

المؤلفون: Szymanski, Wiktor, Ourailidou, Maria E., Velema, Willem A., Dekker, Frank J., Feringa, Ben L.

المصدر: Chemistry - A European Journal; Nov2015, Vol. 21 Issue 46, p16517-16524, 8p

مصطلحات موضوعية: HISTONE deacetylase inhibitors, DRUG design, CANCER chemotherapy, PHOTOCHEMISTRY, ANTINEOPLASTIC agents, CELL-mediated cytotoxicity