المؤلفون: HaoJie Zhang, Tong Ye, Liu Fengmin, Xiangjun Zhang, Jipeng Wang, Xiaobo Wei, Yun Ping Neo, Huiyan Liu, Haitian Fang

مصطلحات موضوعية: Microbiology, Cell Biology, Genetics, Molecular Biology, Computational Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, results obtained demonstrated, aspartic acid pathway, important precursor substance, 658 genes exhibiting, 636 genes displaying, escherichia coli became, threonine metabolic pathway, mutant strain nxu102, mutant strain compared, transcriptomic analysis revealed, original strain nxu101, isoleucine remains unrevealed, g ., δ, related genes assisted, threonine metabolism pathway, acetic acid accumulation, escherichia coli l, tricarboxylic acid cycle, tricarboxylic acid, mutant strain, original strain, related genes

Relation: https://figshare.com/articles/journal_contribution/Strategies_to_Enhance_l_Isoleucine_Synthesis_by_Modifying_the_Threonine_Metabolism_Pathway_in_Escherichia_coli/25267277

الاتاحة: https://doi.org/10.1021/acsomega.3c07619.s001
https://figshare.com/articles/journal_contribution/Strategies_to_Enhance_l_Isoleucine_Synthesis_by_Modifying_the_Threonine_Metabolism_Pathway_in_Escherichia_coli/25267277

المؤلفون: Lianghong Yin, Dandan Xi, Yuefeng Shen, Nana Ding, Qingsong Shao, Yongchang Qian, Yu Fang

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Ecology, Immunology, Developmental Biology, Computational Biology, Space Science, Biological Sciences not elsewhere classified, tune metabolic flux, rewiring metabolic flux, microbial cell factories, manipulating metabolic flux, food raw materials, bifunctional regulation system, achieving widespread adoption, corynebacterium glutamicum using, target products, soxs exhibited, shikimic acid, serine production, serine biosynthesis, original strain, obstacles arise, multiple genes, microorganism classified, intricate nature

Relation: https://figshare.com/articles/journal_contribution/Rewiring_Metabolic_Flux_in_Corynebacterium_glutamicum_Using_a_CRISPR_dCpf1-Based_Bifunctional_Regulation_System/25132488

الاتاحة: https://doi.org/10.1021/acs.jafc.3c08529.s001
https://figshare.com/articles/journal_contribution/Rewiring_Metabolic_Flux_in_Corynebacterium_glutamicum_Using_a_CRISPR_dCpf1-Based_Bifunctional_Regulation_System/25132488

المؤلفون: Chaoyong Liao, Jian Cui, Mingkun Gao, Bo Wang, Koichi Ito, Yuming Guo, Bingkun Zhang

مصطلحات موضوعية: Microbiology, Pharmacology, Biotechnology, Ecology, Infectious Diseases, Computational Biology, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, utilizing mutation breeding, traditional overexpression systems, strategic modulation resulted, sgrna crispra system, approach effectively combined, original strain nb205, newly engineered strain, inhibiting pathogenic infections, achieve precise regulation, a3e3 notably inhibited, >) natto nb205, bacillus subtilis <, precise regulation, subtilis <, mutant strain, salmonella <, ispe <, ispa <, synthetic pathways, significant enhancement, significant 117

Relation: https://figshare.com/articles/journal_contribution/Dual-sgRNA_CRISPRa_System_for_Enhanced_MK_7_Production_and_i_Salmonella_i_Infection_Mitigation_in_i_Bacillus_subtilis_i_natto_Applied_to_Caco_2_Cells/25199578

الاتاحة: https://doi.org/10.1021/acs.jafc.3c08866.s001
https://figshare.com/articles/journal_contribution/Dual-sgRNA_CRISPRa_System_for_Enhanced_MK_7_Production_and_i_Salmonella_i_Infection_Mitigation_in_i_Bacillus_subtilis_i_natto_Applied_to_Caco_2_Cells/25199578

المؤلفون: Zhijun ZHOU, Lu FENG, Shenglan YUE, Yan PENG, Bin GAO, Deiming JI, Juan LI, Kejin CHEN, Lianzhen LIN, Cesheng LI, Yong Hu, Taojing Li

المصدر: Zhongguo shuxue zazhi, Vol 36, Iss 3, Pp 199-203 (2023)

مصطلحات موضوعية: sars-cov-2, original strain, variant strain, elisa-igg potency, convalescent plasma, neutralizing antibody potency, qualified rate of plasma collection, Diseases of the blood and blood-forming organs, RC633-647.5, Medicine

وصف الملف: electronic resource

Relation: https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2023.03.001&lang=en; https://doaj.org/toc/1004-549X

URL الوصول: https://doaj.org/article/be727f26effc4ba39fe71b3d5ac5a111

المؤلفون: Xiaoyu Han, Jingze Chen, Lu Chen, Xi Jia, Yanqing Fan, Yuting Zheng, Osamah Alwalid, Jie Liu, Yumin Li, Na Li, Jin Gu, Jiangtao Wang, Heshui Shi

المصدر: Biomedicines; Volume 11; Issue 3; Pages: 901

مصطلحات موضوعية: SARS-CoV-2, Delta variant, Omicron variant, original strain, CT imaging

وصف الملف: application/pdf

Relation: Microbiology in Human Health and Disease; https://dx.doi.org/10.3390/biomedicines11030901

الاتاحة: https://doi.org/10.3390/biomedicines11030901

المؤلفون: Natasha Gupta Vergara (14313144), Megan Gatchel (14313147), Cameron F. Abrams (1321032)

مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Pharmacology, Evolutionary Biology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, two proteins away, scale quaternary flexibility, entropically favorable increase, calculations correctly predict, receptor binding domain, increases binding affinity, converting enzyme 2, less favorable enthalpy, ace2 ), primarily, cov ‑ 2, energy calculations, weaker interactions, residue mutations, residue interactions, qualitatively assess, peripheral interactions, original strain, n501y ’, n501y mutation, n501y causes, may seem

Relation: https://figshare.com/articles/journal_contribution/Entropic_Overcompensation_of_the_N501Y_Mutation_on_SARS-CoV_2_S_Binding_to_ACE2/21799668

الاتاحة: https://doi.org/10.1021/acs.jcim.2c01246.s002

المؤلفون: Shuai Ma (414625), Tianyuan Su (3454208), Jinming Liu (124265), Xuemei Lu (217979), Qingsheng Qi (256048)

مصطلحات موضوعية: Microbiology, Genetics, Cancer, Space Science, Biological Sciences not elsewhere classified, rational design encounter, least 2 magnitudes, intracellular alternative end, electroporation efficiency increased, complex gene functions, allows genomic deletions, random genomic deletions, mediated random deletion, named “ transposon, five reduction cycles, random positions, widely applied, various sizes, using e, synthetic biology, strand breaks, small e, original strain, minimal genomes, metabolic engineering, limited knowledge, joining mechanism, important strategy, growth rates, escherichia coli

Relation: https://figshare.com/articles/journal_contribution/Reduction_of_the_Bacterial_Genome_by_Transposon-Mediated_Random_Deletion/19104179

الاتاحة: https://doi.org/10.1021/acssynbio.1c00353.s001

المؤلفون: Yi Rao (469255), Peifen Li (5231681), Xinxin Xie (2104246), Jiemin Li (9421540), Yongqing Liao (11349407), Xin Ma (37268), Dongbo Cai (3948317), Shouwen Chen (3550844)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Physiology, Pharmacology, Biotechnology, Ecology, Developmental Biology, Science Policy, Plant Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, via manipulating synthetic, red fluorescent protein, pucheriminic acid yield, pucheriminic acid synthesis, original strain dw2, important industrial strain, green fluorescent protein, 6 – 741, tuning gene expression, tuned gene expression, keratinase expression assays, gene expression hindered, undh , ubay , baca , bacillus licheniformis dw2, bacillus licheniformis <, strong )

Relation: https://figshare.com/articles/journal_contribution/Construction_and_Characterization_of_a_Gradient_Strength_Promoter_Library_for_Fine-Tuned_Gene_Expression_in_i_Bacillus_licheniformis_i_/16527107

الاتاحة: https://doi.org/10.1021/acssynbio.1c00242.s001

المؤلفون: Tetsuo Nunoya, Kazuya Shirato, Tsuchiya Kotaro, Kouich Kusanagi, Asuka Hirai, Madoka Maejima, Natsumi Takeyama, Yasushi Ami, Fumihiro Taguchi

المصدر: Archives of Virology

مصطلحات موضوعية: viruses, Adaptation, Biological, Virulence, medicine.disease_cause, Severe Acute Respiratory Syndrome, Virus, Cell Fusion, Original Strain, Mice, Viral Envelope Proteins, Nidovirales, Serial passage, Pregnancy, Virology, medicine, Animals, Serial Passage, Cells, Cultured, Coronavirus, Mice, Inbred ICR, Cell fusion, Membrane Glycoproteins, biology, Porcine epidemic diarrhea virus, Brain, General Medicine, biology.organism_classification, Disease Models, Animal, Viral replication, Amino Acid Substitution, Spike Glycoprotein, Coronavirus, Vero Cell, Female, Original Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587a254b3dc74992fa69fd1c3d5a1b25
https://pubmed.ncbi.nlm.nih.gov/20827493

المؤلفون: Jianli Tang (6896279), Haocheng He (6885530), Yunlong Li (117641), Zhudong Liu (346320), Ziyuan Xia (8439717), Li Cao (106383), Zirong Zhu (9162950), Ling Shuai (3455570), Yang Liu (4829), Qianqian Wan (9712311), Yuewen Luo (8496288), Youming Zhang (565208), Jie Rang (703896), Liqiu Xia (703901)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Molecular Biology, Ecology, Developmental Biology, Hematology, Chemical Sciences not elsewhere classified, spectrum biopesticide produced, comparative proteomics reveals, comparative proteomics revealed, transcriptional regulator sp13016, ora pogona <, saccharopolyspora pogona, sp13016 <, saccharopolysp <, actinomycetes <, still unknown, significant decrease, secondary metabolism, research helps, regulatory mechanism, phenotypic changes, original strain, natural products, highly effective, highly associated, growth inhibition

Relation: https://figshare.com/articles/journal_contribution/Comparative_Proteomics_Reveals_the_Effect_of_the_Transcriptional_Regulator_Sp13016_on_Butenyl-Spinosyn_Biosynthesis_in_i_Saccharopolysp_i_i_ora_pogona_i_/16822152

الاتاحة: https://doi.org/10.1021/acs.jafc.1c03654.s001

المؤلفون: 林莉

المساهمون: 林琼武

المصدر: http://210.34.4.13:8080/lunwen/detail.asp?serial=52906.

مصطلحات موضوعية: 凡纳滨对虾, 负选择, 原种亲虾, 池养亲虾, 生殖性能, 卵子质量, 幼体质量, Litopenaeus vannamei, negative selection, original strain broodstock, pond-reared broodstock, reproductive performance, egg quality, larval quality

Relation: http://210.34.4.28/opac/openlink.php?strText=55561&doctype=ALL&strSearchType=callno; http://dspace.xmu.edu.cn/handle/2288/129860

الاتاحة: http://dspace.xmu.edu.cn/handle/2288/129860