المؤلفون: Hauke Drechsler, Mariola Chacón, Dalileh Nabi, Stefan Diez, Nadine Schuler, Franz Korn, Johannes Pschirer, Rolf Jessberger

المساهمون: Projekt DEAL, German Research Foundation, European Commission, Universidad de Sevilla, Universidad de Sevilla. Departamento de Biología Celular, Sociedad Alemana de Investigación, [Nabi,D, Pschirer,J, Korn,F, Schuler,N, Jessberger,R, Chacón,M] Institute of Physiological Chemistry, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. [Drechsler,H, Diez,S] B CUBE-Center for Molecular Bioengineering, Technische Universität Dresden, Dresden, Germany. [Diez,S] Cluster of Excellence Physics of Life, Technische Universität Dresden, Dresden, Germany. [Diez,S] Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany. [Nabi,D] Department of Neuropediatrics Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany. [Chacón,M] CABIMER, Centro Andaluz de Biología Molecular & Medicina Regenerativa, Sevilla, Spain., Funding enabled and organized by Projekt DEAL

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: Checkpoints, Metafase, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle::Cell Division::Cell Nucleus Division::Meiosis [Medical Subject Headings], General Physics and Astronomy, Microtubules, Spindle pole body, Chromosome segregation, Mice, Oogenesis, Chromosome Segregation, Organisms::Eukaryota::Animals [Medical Subject Headings], Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Cytoskeleton::Microtubule-Organizing Center [Medical Subject Headings], chromosome, Kinetochores, Multidisciplinary, Kinetochore, Chemistry, Oocitos, Microtúbulos, Cell biology, Meiosis, Spindle checkpoint, Aneuploidia, Mammalia, Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Cytoskeleton::Microtubules [Medical Subject Headings], Female, Spindle poles, Genomic instability, Science, Phenomena and Processes::Genetic Phenomena::Genetic Processes::Cell Division::Cell Nucleus Division::Chromosome Segregation [Medical Subject Headings], macromolecular substances, Article, General Biochemistry, Genetics and Molecular Biology, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle::Cell Division::Cell Nucleus Division::Metaphase [Medical Subject Headings], Centromere, Animals, Metaphase, centrome protein v, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice [Medical Subject Headings], General Chemistry, Aneuploidy, Spindle apparatus, Segregación cromosómica, Check Tags::Female [Medical Subject Headings], Polos del huso mitótico, Oocytes, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle::Cell Cycle Checkpoints::M Phase Cell Cycle Checkpoints [Medical Subject Headings], Anatomy::Cells::Germ Cells::Ovum::Oocytes [Medical Subject Headings], M Phase Cell Cycle Checkpoints, amino terminal sequence, Multipolar spindles, Microtubule-Organizing Center

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cca62e3359979320e63143ff725d29c
https://doaj.org/article/dcf979a98c334436b8bb21f92662b1b9

المؤلفون: Teresa L. Ramos, Alfonso Rodríguez-Gil, José Antonio Pérez-Simón, Melanie Nufer, Teresa Caballero-Velázquez, Estefanía García-Guerrero, María Victoria Barbado, Rocío Caracuel-García, María José Robles-Frías

المساهمون: Universidad de Sevilla. Departamento de Medicina, Universidad de Sevilla. Departamento de Fisiología Médica y Biofísica, Universidad de Sevilla. Departamento de Citología e Histología Normal y Patológica, Takeda Pharmaceutical Company, Asociación Española Contra el Cáncer, Centro de Investigación Biomédica en Red Cáncer (España), [Ramos,TL, García-Guerrero,E, Caballero-Velázquez,T, Rodríguez-Gil,A, Caracuel-García,R, Nufer,M, Robles-Frías,MJ, Barbado,MV, Pérez-Simón,JA] Instituto de Biomedicina de Sevilla (IBIS/CSIC), CIBERONC, Universidad de Sevilla, Sevilla, Spain. [Ramos,TL] Division of Blood and Marrow Transplantation, Stanford University School of Medicine, Stanford, CA, USA. [Caballero-Velázquez,T, Pérez-Simón,JA] Department of Hematology, University Hospital Virgen del Rocio, Universidad de Sevilla, Sevilla, Spain., Takeda company (PCRS-2016-101751) partially supported the study, This work has been partially supported by the CIBERONC (CB16/12/00480), and TerCel 16/0011/0035. Spanish Association Against Cancer (AECC-POSTD18023LOPE) fellowship (TLR).

المصدر: Bone Marrow Transplantation
Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: Graft vs Host Disease, Phenomena and Processes::Immune System Phenomena::Immune System Processes::Transplantation Immunology::Graft vs Host Reaction [Medical Subject Headings], Disease, Graft-versus-host disease, Inhibidores de proteasoma, Ixazomib, Mice, chemistry.chemical_compound, immune system diseases, Organisms::Eukaryota::Animals [Medical Subject Headings], Proteasome inhibitor, Bone Marrow Transplantation, Leukemia, Effector, Médula ósea, Hematology, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Transplantation::Tissue Transplantation::Bone Marrow Transplantation [Medical Subject Headings], Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Amino Acids::Glycine [Medical Subject Headings], surgical procedures, operative, medicine.anatomical_structure, Linfocitos B, medicine.drug, Boron Compounds, Bone marrow transplantation, Glycine, Graft vs Leukemia Effect, Enfermedad injerto contra huésped, Article, Immune system, medicine, Animals, Bone marrow, Leucemia, B cells, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice [Medical Subject Headings], Transplantation, business.industry, Immunity, Phenomena and Processes::Immune System Phenomena::Immunity [Medical Subject Headings], Translational research, medicine.disease, Diseases::Immune System Diseases::Graft vs Host Disease [Medical Subject Headings], chemistry, Immunology, business, Chemicals and Drugs::Inorganic Chemicals::Boron Compounds [Medical Subject Headings]

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227fcab3b1ab31aee8f3643f5967ee34
https://doi.org/10.1038/s41409-021-01452-1

المؤلفون: Sara Sopeña-Torres, Ana María Sánchez-Tévar, Hung K. Doan, Diego Romero, Johan H. J. Leveau, Antonio de Vicente, Luis Díaz-Martínez, Jesús Hierrezuelo, Juan Antonio Guadix, Maria Luisa Antequera-Gómez

المساهمون: [Antequera-Gómez,ML, Díaz-Martínez,L, Sopeña-Torres,S, Hierrezuelo,J, deVicente, Romero,D] Departamento de Microbiología, Instituto de Hortofruticultura Subtropical y Mediterranea 'La Mayora', Universidad de Malaga-Consejo Superior de Investigaciones Cientíıficas (IHSM-UMA-CSIC), Universidad de Malaga, Malaga, Spain. [Guadix,JA, Sánchez-Tévar,AM] Departamento de Biología Animal, Facultad de Ciencias, Universidad de Malaga - IBIMA, Spain. [Guadix,JA, Sánchez-Tévar,AM] Centro Andaluz de Nanomedicina y Biotecnología (BIONAND), Junta de Andalucía, Universidad de Málaga, Málaga, Spain. [Doan,HK, Leveau,JHJ] Department of Plant Pathology, University of California, Davis, CA, USA., This work was supported by grants from European Research Council Starting Grant (BacBio 637971), and Plan Nacional de I + D+i of Ministerio de Economía y Competitividad, Ministerio de Ciencia e Innovacion (AGL2016-78662-R and PID2019-107724GB-I00). Johan HJ Leveau was financed by USDA-NIFA grant number 2014-67017-21695. Juan Antonio Guadix acknowledges financial support by grant (PIER-0084-2019) from Proyectos de Investigacion en Salud de Junta de Andalucía

المصدر: Microbial Biotechnology
Microbial Biotechnology, Vol 14, Iss 4, Pp 1550-1565 (2021)

مصطلحات موضوعية: Spores, Organisms::Bacteria::Endospore-Forming Bacteria::Gram-Positive Endospore-Forming Bacteria::Gram-Positive Endospore-Forming Rods::Bacillaceae::Bacillus::Bacillus cereus [Medical Subject Headings], Bacillus cereus, Human pathogen, Enterotoxin, Applied Microbiology and Biotechnology, Biochemistry, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Foodborne Diseases, Enterotoxins, Mice, Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Microbiology::Environmental Microbiology::Food Microbiology [Medical Subject Headings], Phenomena and Processes::Physiological Phenomena::Physiological Processes::Growth and Development::Morphogenesis::Metamorphosis, Biological::Life Cycle Stages [Medical Subject Headings], Vegetables, Organisms::Eukaryota::Animals [Medical Subject Headings], Pathogen, Research Articles, 2. Zero hunger, 0303 health sciences, Food poisoning, biology, digestive, oral, and skin physiology, 3. Good health, Cereus, Esporas, Diseases::Chemically-Induced Disorders::Poisoning::Foodborne Diseases [Medical Subject Headings], Anatomy::Digestive System::Gastrointestinal Tract::Intestines [Medical Subject Headings], Research Article, Biotechnology, Enfermedades transmitidas por los alimentos, Health Care::Environment and Public Health::Public Health::Disease Outbreaks [Medical Subject Headings], Anatomy::Plant Structures::Plant Components, Aerial::Plant Leaves [Medical Subject Headings], Organisms::Organism Forms::Spores [Medical Subject Headings], Bioengineering, Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Emetics [Medical Subject Headings], Microbiology, Enterotoxinas, 03 medical and health sciences, medicine, Animals, Humans, Food microbiology, 030304 developmental biology, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice [Medical Subject Headings], Life Cycle Stages, 030306 microbiology, fungi, Eméticos, biology.organism_classification, medicine.disease, Organisms::Eukaryota::Plants::Plants, Edible::Vegetables [Medical Subject Headings], Diseases::Animal Diseases::Disease Models, Animal [Medical Subject Headings], Spore, Chemicals and Drugs::Biological Factors::Toxins, Biological::Enterotoxins [Medical Subject Headings], Food Microbiology, bacteria, Emetics, TP248.13-248.65

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2470a25badf013ec9813facec519d3c1
https://doi.org/10.1111/1751-7915.13816

المؤلفون: Daniel Otero-Albiol, Sandra Muñoz-Galván, Eva M. Verdugo-Sivianes, Amancio Carnero, Ana M. Rojas

المساهمون: [Verdugo-Sivianes,EM, Muñoz-Galván,S, Otero-Albiol,D, Carnero,AS] Instituto de Biomedicina de Sevilla, IBIS, Hospital Universitario Virgen del Rocio, Consejo Superior de Investigaciones Científicas, Universidad de Sevilla, Spain. [Verdugo-Sivianes,EM, Carnero,AS] CIBERONC, Instituto de Salud Carlos III, Madrid, Spain. [Rojas,AM] Centro Andaluz de Biología del Desarrollo (CABD), CSIC-Universidad Pablo de Olavide, Sevilla, Spain., This work was supported by grants from the Ministerio de Ciencia, Innovación y Universidades (MCIU) Plan Estatal de I+D+I 2018, a la Agencia Estatal de Investigación (AEI) y al Fondo Europeo de Desarrollo Regional (MCIU/AEI/FEDER, UE): RTI2018-097455-B-I00 and RTI2018-096735-B-I00grant from AEI-MICIU/FEDER (RED2018-102723-T), from CIBER de Cáncer (CB16/12/00275), co-funded by FEDER from Regional Development European Funds (European Union), from Consejeria de Salud (PI-0397-2017) and Consejeria of Economía, Conocimiento, Empresas y Universidad of the Junta de Andalucia (P18-RT-2501). Special thanks are also due to the Fundacion AECC and Fundacion Eugenio Rodriguez Pascual for supporting this work., Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), European Commission, Centro de Investigación Biomédica en Red Cáncer (España), Junta de Andalucía, Fundación Científica Asociación Española Contra el Cáncer, Fundación Eugenio Rodríguez Pascual

المصدر: Theranostics
Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: 0301 basic medicine, Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor [Medical Subject Headings], Proteína de retinoblastoma, Carcinogenesis, Mutant, Medicine (miscellaneous), Anatomy::Cells::Stem Cells::Neoplastic Stem Cells [Medical Subject Headings], medicine.disease_cause, environment and public health, Retinoblastoma Protein, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Mice, 0302 clinical medicine, Breast cancer, pRB, Anatomy::Cells::Cells, Cultured::Cell Line [Medical Subject Headings], stem cell phenotype, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Nerve Tissue Proteins [Medical Subject Headings], Protein Phosphatase 1, Organisms::Eukaryota::Animals [Medical Subject Headings], Proteína fosfatasa 1, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Evaluation Studies as Topic::Drug Evaluation, Preclinical::Drug Screening Assays, Antitumor::Xenograft Model Antitumor Assays [Medical Subject Headings], Phosphorylation, Phenomena and Processes::Metabolic Phenomena::Metabolism::Phosphorylation [Medical Subject Headings], Pharmacology, Toxicology and Pharmaceutics (miscellaneous), Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle [Medical Subject Headings], Cell Line, Transformed, Mutation, Chemicals and Drugs::Macromolecular Substances::Polymers::Biopolymers::Microfilament Proteins [Medical Subject Headings], Retinoblastoma, Línea celular, Microfilament Proteins, Proteína 1 de unión a retinoblastoma, Cell cycle, Diseases::Neoplasms::Neoplastic Processes::Carcinogenesis [Medical Subject Headings], PP1, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle::Cell Cycle Checkpoints::G1 Phase Cell Cycle Checkpoints [Medical Subject Headings], Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Neoplasm Proteins::Tumor Suppressor Proteins::Tumor Suppressor Protein p53 [Medical Subject Headings], Gene Expression Regulation, Neoplastic, Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Transformed [Medical Subject Headings], Diseases::Neoplasms::Neoplasms by Site::Eye Neoplasms::Retinal Neoplasms [Medical Subject Headings], SPINOPHILIN, 030220 oncology & carcinogenesis, Neoplasias de la mama, Neoplastic Stem Cells, Cell lines, Female, biological phenomena, cell phenomena, and immunity, Research Paper, Signal Transduction, Carcinogénesis, cancer stem cell, animal structures, Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation [Medical Subject Headings], Stem cell phenotype, Mice, Nude, Breast Neoplasms, Nerve Tissue Proteins, macromolecular substances, Biology, Resting Phase, Cell Cycle, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Neoplasm Proteins::Tumor Suppressor Proteins::Retinoblastoma Protein [Medical Subject Headings], Dephosphorylation, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Esterases::Phosphoric Monoester Hydrolases::Phosphoprotein Phosphatases::Protein Phosphatase 1 [Medical Subject Headings], 03 medical and health sciences, Cancer stem cell, Cell Line, Tumor, medicine, Animals, Humans, Diseases::Neoplasms::Neoplasms by Site::Breast Neoplasms [Medical Subject Headings], Células madre neoplásicas, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice [Medical Subject Headings], Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Signal Transduction [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice::Mice, Mutant Strains::Mice, Nude [Medical Subject Headings], pocket proteins, medicine.disease, G1 Phase Cell Cycle Checkpoints, Xenograft Model Antitumor Assays, Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Gene Expression Regulation, Neoplastic [Medical Subject Headings], enzymes and coenzymes (carbohydrates), tumorigenesis, 030104 developmental biology, Check Tags::Female [Medical Subject Headings], Tumor progression, Cell culture, Retinoblastoma protein, Tumorigenesis, Cancer research, Tumor Suppressor Protein p53, Pocket proteins, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Holoenzymes [Medical Subject Headings]

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc94057a330544993a83e9fc556b68b2
http://europepmc.org/articles/PMC7847670

المؤلفون: Antonio Campos-Caro, Eduardo García Fuentes, Francisco Javier Bermúdez-Silva, Nadia Cobo-Vuilleumier, Petra I. Lorenzo, Christian Claude Lachaud, Benoit R. Gauthier, Valentine Comaills, Esther Fuente-Martin, Jose C. Reyes, Alejandro Martin-Montalvo, Alejandra Crespo Barreda, José A Guerrero Martínez, Sabrina Rivero Canalejo, Jesús Ángel Pérez-Cabello, Franz Martín, Manuel Álvarez Dolado, José Manuel Mellado-Gil, Eugenia Martin Vázquez, Gemma Rojo-Martínez, Silvana Y. Romero-Zerbo, David Pozo, Jaime M. Franco, Manuel Aguilar-Diosdado, Livia López-Noriega

المساهمون: Junta de Andalucía, European Commission, Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Fundación Vencer el Cancer, Fundación DiabetesCERO, Juvenile Diabetes Research Foundation, Instituto de Salud Carlos III, Asociación Española Contra el Cáncer, [Lorenzo,PI, Martin Vazquez,E, López-Noriega,L, Fuente-Martín,E, Mellado-Gil,JM, Franco,JM, Cobo-Vuilleumier,N, Guerrero Martínez,JA, Perez-Cabello,JA, Lachaud,CC, Crespo Barreda,A, Martin-Montalvo,A, Álvarez Dolado,M, Martin,F, Comaills,V, Reyes,JC, Gauthier,BR] Andalusian Center of Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucía-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain. [Romero-Zerbo,SY, Rojo-Martinez,G, Bérmudez-Silva,FJ] Unidad de Gestión Clínica Intercentros de Endocrinología y Nutrición, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Spain. [Rivero Canalejo,S] Department of Normal and Pathological Histology and Cytology, University of Seville School of Medicine, Seville, Spain. University Hospital 'Puerta del Mar', Instituto de Investigación e Innovación en Ciencias Biomédicas de la Provincia de Cádiz (INiBICA), Cádiz, Spain. [Campos-Caro,A, Aguilar-Diosdado,M] Department of Normal and Pathological Histology and Cytology, University of Seville School of Medicine, Seville, Spain. 4. University Hospital 'Puerta del Mar', Instituto de Investigación e Innovación en Ciencias Biomédicas de la Provincia de Cádiz (INiBICA), Cádiz, Spain. [Aguilar-Diosdado,M] Endocrinology and Metabolism Department, University Hospital 'Puerta del Mar', Instituto de Investigación e Innovación en Ciencias Biomédicas de la Provincia de Cádiz (INiBICA), Cádiz, Spain. [García Fuentes,E] Unidad de Gestión Clínica de Aparato Digestivo, Hospital Universitario Virgen de la Victoria, Instituto de Investigación Biomédica de Málaga (IBIMA), Spain. [Martín,F, Rojo-Martínez,G, Bérmudez-Silva,FJ, Gauthier,BR] Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain., The authors are supported by grants from the Consejería de Salud, Fundación Pública Andaluza Progreso y Salud, Junta de Andalucía (PI-0727-2010 and PI-0001-2020 to B.R.G., PI-0085-2013 to P.I.L., PI-0006-2016 to E.F.M., PI-0574-2012 to S.Y.R.Z, PI-0247-2016 to F.J.B.S.), the Consejería de Economía, Innovación y Ciencia (P10.CTS.6359 to B.R.G., CTS.8081 to E.G.F.), the Ministerio de Economía y Competitividad co-funded by Fondos FEDER (PI10/00871, PI13/00593 and BFU2017-83588-P to B.R.G., PRE2018-084907 to M.E.M.V.G., PI13/00309, PI17/01004 to F.J.B.S., BFU2014-5343-P to J.C.R., and AGL2017-86927-R to F.M.), Vencer el Cancer (B.R.G), DiabetesCero (B.R.G.) and the Juvenile Diabetes Research Foundation (17-2013-372 and 2-SRA-2019-837-S-B to B.R.G.). E.F.M. was a recipient of a Juan de la Cierva Incorporación Fellowship from the Ministerio de Economía y Competitividad (IJCI-2015-26238). S.Y.R.Z is a recipient of a postdoctoral fellowship from Consejería de Salud, Junta de Andalucía (RH-0070-2013). L.L.N. is supported by a Consejeria de Economia, Conocimiento, Empresas y Universidad postdoctoral fellowship (DOC_00652). F.J.B.S. and E.G.F. are recipients of 'Nicolás Monardes' research contracts from Consejería de Salud Junta de Andalucía, (C-0070-2012 and C-0031-2016). A.M.M. is supported by CPII19/00023 and PI18/01590 from the Instituto de Salud Carlos III co-funded by Fondos FEDER. CIBERDEM is an initiative of the Instituto de Salud Carlos III. V.C. is supported by a AECC investigator award.

المصدر: Theranostics
Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: Astrocitos, Male, Interleukin-1beta, Medicine (miscellaneous), Adipose tissue, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Mice, ORY1001, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Nerve Tissue Proteins [Medical Subject Headings], Organisms::Eukaryota::Animals [Medical Subject Headings], Glucose homeostasis, Gliosis, RNA-Seq, RNA, Small Interfering, Anatomy::Nervous System::Neurons [Medical Subject Headings], Pharmacology, Toxicology and Pharmaceutics (miscellaneous), Metabolismo, Histone Demethylases, Neurons, Chemicals and Drugs::Carbohydrates::Glycosides::Glucosides [Medical Subject Headings], High Mobility Group Proteins, metabesity, Middle Aged, Mitochondria, Astrogliosis, medicine.anatomical_structure, Adipose Tissue, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Oxidoreductases Acting on CH-NH Group Donors::Oxidoreductases, N-Demethylating::Histone Demethylases [Medical Subject Headings], Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus, Type 2 [Medical Subject Headings], medicine.symptom, Co-Repressor Proteins, Research Paper, Astrocyte, Adult, medicine.medical_specialty, Cell Survival, Anatomy::Nervous System::Neuroglia::Astrocytes [Medical Subject Headings], Hypothalamus, Nerve Tissue Proteins, Inflammation, Biology, Diet, High-Fat, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Nuclear Proteins::Chromosomal Proteins, Non-Histone::High Mobility Group Proteins [Medical Subject Headings], Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet::Diet, High-Fat [Medical Subject Headings], Insulin resistance, Downregulation and upregulation, Internal medicine, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Survival [Medical Subject Headings], Glial Fibrillary Acidic Protein, medicine, Animals, Humans, Obesity, Metabesity, Persons::Persons::Age Groups::Adult [Medical Subject Headings], Inflamación, astrocytes, Persons::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings], Anatomy::Nervous System::Central Nervous System::Brain::Limbic System::Hypothalamus [Medical Subject Headings], Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Gliosis [Medical Subject Headings], medicine.disease, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Transcription Factors::Repressor Proteins::Co-Repressor Proteins [Medical Subject Headings], Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity [Medical Subject Headings], Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines::Interleukins::Interleukin-1::Interleukin-1beta [Medical Subject Headings], Mice, Inbred C57BL, Metabolism, Glucose, Endocrinology, Diabetes Mellitus, Type 2, inflammation, Astrocytes, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice::Mice, Inbred Strains [Medical Subject Headings], HMG20A, Neuron, metabolism

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353d6c4b8b7acf4f3e6f9f951fd6d22d
https://doi.org/10.7150/thno.57237

المؤلفون: Israel Guerrero-Cózar, María Jesús Zamorano, Pedro Seoane, Cathaysa Pérez-García, Fernando Cruz, M. Gonzalo Claros, Hicham Benzekri, Manuel Manchado, Marta Gut, Juan José García Sánchez

المساهمون: [Guerrero-Cózar,I, Manchado,M] IFAPA Centro El Toruño, Junta de Andalucía, El Puerto de Santa María, Cádiz, Spain. [Perez-Garcia,C, Zamorano,MJ] Aquaculture Research Group (GIA), IU-ECOAQUA, Universidad de Las Palmas de Gran Canaria, Telde, Spain. [Benzekri,H, Seoane,P, Claros,MG] Department of Molecular Biology and Biochemistry, Universidad de Málaga, Málaga, Spain. [Sánchez,JJ] Instituto Nacional de Toxicología Y Ciencias Forenses (INT), La Laguna, Sta. Cruz de Tenerife, Spain. [Cruz,F, Gut,M] CNAG‑CRG, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain. [Claros,MG] CIBER de Enfermedades Raras (CIBERER), Málaga, Spain. [Claros,MG] Institute of Biomedical Research in Málaga (IBIMA), IBIMA-RARE, Málaga, Spain. [Claros,MG] Instituto de Hortofruticultura Subtropical Y Mediterránea (IHSM-UMA-CSIC), Málaga, Spain. [Manchado,M] 'Crecimiento Azul', Centro IFAPA El Toruño, Unidad Asociada Al CSIC', El Puerto de Sta. María, Spain., This study was funded by project RTA2017-00054-C03-01, RTA2017-00054-C03-02 and RTA2017-00054-C03-03 funded from MCIU/AEI/FEDER, UE. IGC is funded by a predoctoral fellowship from INIA.

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports

مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, Genetic Linkage, Multiplex polymerase chain reaction, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Pedigree [Medical Subject Headings], Llenguados, 01 natural sciences, Genome, Organisms::Eukaryota::Animals [Medical Subject Headings], Multiplex, Phylogeny, Multidisciplinary, Mapeo cromosómico, Contig, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Fishes::Flatfishes [Medical Subject Headings], Femenino, Chromosome Mapping, food and beverages, Sintenía, Pedigree, Flatfishes, Microsatellite, Medicine, Female, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Chromosome Mapping::Physical Chromosome Mapping [Medical Subject Headings], Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Tandem Repeat Sequences::Microsatellite Repeats [Medical Subject Headings], Science, Computational biology, Biology, Variación genética, 010603 evolutionary biology, Synteny, Article, 03 medical and health sciences, Phenomena and Processes::Genetic Phenomena::Genetic Linkage [Medical Subject Headings], Linaje, Reacción en cadena de la polimerasa multiplex, Animals, Genetic variation, Genotyping, Genoma, Animal breeding, Genetic diversity, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Genetic Association Studies::Genome-Wide Association Study [Medical Subject Headings], Phenomena and Processes::Genetic Phenomena::Sequence Homology::Sequence Homology, Nucleic Acid::Synteny [Medical Subject Headings], Genòmica, 030104 developmental biology, Genetic marker, Phenomena and Processes::Genetic Phenomena::Phylogeny [Medical Subject Headings], Genetic markers, Peces planos, Genètica, Genome-Wide Association Study, Microsatellite Repeats

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document; application/vnd.ms-excel; application/vnd.openxmlformats-officedocument.spreadsheetml.sheet

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0dffc14115ae2cf21f126c7abfa957
https://doaj.org/article/622ae00987114c2381248540e95d2270

المؤلفون: Ana R. Quesada, Beatriz Martínez-Poveda, Miguel Ángel Medina, Manuel Marí-Beffa, Mª Carmen Ocaña

المساهمون: [Ocaña,MC, Martínez-Poveda,B, Quesada,AR, Medina,MÁ] Universidad de Málaga, Andalucía Tech, Departamento de Biología Molecular y Bioquímica, Facultad de Ciencias, Málaga, Spain. [Ocaña,MC, Medina,MÁ] IBIMA (Biomedical Research Institute of Málaga), Málaga, Spain. [Marí-Beffa,M] Universidad de Málaga, Andalucía Tech, Departamento de Biología Celular, Genética y Fisiología, Facultad de Ciencias, Málaga, Spain. [Quesada,AR, Medina,MÁ] CIBER de Enfermedades Raras (CIBERER), Málaga, Spain., Mª Carmen Ocaña is recipient of a predoctoral FPU grant from the Spanish Ministry of Education, Culture and Sport. This work was supported by grants PID2019-105010RB-100 (MINECO and FEDER), UMA18-FEDERJA-220 (Andalusian Government and FEDER) and funds from group BIO 267 (Andalusian Government), as well as funds from 'Plan Propio de Investigación y Transferencia (Universidad de Málaga). The 'CIBER de Enfermedades Raras' is an initiative from the ISCIII (Spain).

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports

مصطلحات موضوعية: Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation [Medical Subject Headings], Angiogenesis, Pyridines, Endothelial cells, Glucose uptake, Cellular differentiation, Chemicals and Drugs::Carbohydrates::Monosaccharides::Hexoses::Glucose [Medical Subject Headings], lcsh:Medicine, Chick Embryo, Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Pyridines [Medical Subject Headings], Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Movement [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Neovascularization, Cell Movement, Phenomena and Processes::Circulatory and Respiratory Physiological Phenomena::Cardiovascular Physiological Phenomena::Cardiovascular Physiological Processes::Neovascularization, Physiologic [Medical Subject Headings], Organisms::Eukaryota::Animals [Medical Subject Headings], Anilides, lcsh:Science, Anilidas, Cell proliferation, Cells, Cultured, Anatomy::Cells::Epithelial Cells::Endothelial Cells::Human Umbilical Vein Endothelial Cells [Medical Subject Headings], Tube formation, Multidisciplinary, Chemistry, Phenomena and Processes::Physiological Phenomena::Physiological Processes::Growth and Development::Growth::Cell Growth Processes::Cell Proliferation [Medical Subject Headings], Cell Differentiation, Anatomy::Animal Structures::Embryo, Nonmammalian::Chick Embryo [Medical Subject Headings], Cell biology, Endothelial stem cell, MCF-7 Cells, Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor::MCF-7 Cells [Medical Subject Headings], medicine.symptom, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Artiodactyla::Ruminants::Cattle [Medical Subject Headings], Proliferación celular, Neovascularization, Physiologic, Article, Target identification, medicine, Human Umbilical Vein Endothelial Cells, Animals, Humans, Chemicals and Drugs::Organic Chemicals::Amides::Anilides [Medical Subject Headings], Cell Proliferation, Cell growth, lcsh:R, Células endoteliales, Glucose, Anatomy::Cells::Cells, Cultured [Medical Subject Headings], Glucosa, Cancer cell, Cattle, lcsh:Q, Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor::HeLa Cells [Medical Subject Headings], Tumour angiogenesis, HeLa Cells

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b097a600bf71036a7d30f9a11fa7e36
http://link.springer.com/article/10.1038/s41598-020-63232-z

المؤلفون: José Pedro De La Cruz Cortés, Leticia Vallejo-Carmona, María Monsalud Arrebola, Esther Martín-Aurioles, María Dolores Rodriguez-Pérez, Laura Ortega-Hombrados, Cristina Verdugo, María África Fernández-Prior, Alejandra Bermúdez-Oria, José Antonio González-Correa

المساهمون: [De La Cruz Cortés,JP, Rodriguez-Pérez,MD, Ortega-Hombrados,L, Verdugo,C, González-Correa,JA] Departmento de Farmacología, Instituto de Investigación Biomédica (IBIMA), Facultad de Medicina, Universidad de Málaga, Málaga, Spain. [Vallejo-Carmona,L] Facultad de Enfermería, Universidad Ana G. Mendez, Recinto Cupei, San Juan, Puerto Rico. [Arrebola,MM] UGC Laboratorio Clínico, Hospital de la Axarquía, AGSEMA, Málaga, Spain. [Martín-Aurioles,E] Distrito Sanitario Málaga-Guadalhorce, UGC La Roca, Málaga, Spain. [Fernández-Prior,MÁ, Bermúdez-Oria,A] Consejo Superior de Investigaciones Científicas (CSIC), Instituto de la Grasa, Seville, Spain., This study was supported, in part, by the Consejería de Salud. Junta de Andalucía (Spain), Proyectos de Investigación en Salud [Regional Ministry of Health. Junta de Andalucía (Spain), Health Research Projects] (PI-0129-2017), Junta de Andalucía

المصدر: Antioxidants; Volume 10; Issue 12; Pages: 1983
Antioxidants
Digital.CSIC. Repositorio Institucional del CSIC
instname
Antioxidants, Vol 10, Iss 1983, p 1983 (2021)

مصطلحات موضوعية: Polifenoles, hydroxytyrosol, extra-virgin olive oil polyphenols, 3′,4′-dihidroxifenilglicol, oxidative stress, cardiovascular, Physiology, Clinical Biochemistry, Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons, Cyclic::Hydrocarbons, Aromatic::Benzene Derivatives::Phenols::Polyphenols [Medical Subject Headings], Phenomena and Processes::Circulatory and Respiratory Physiological Phenomena::Blood Physiological Phenomena::Blood Physiological Processes::Hemorheology::Platelet Aggregation [Medical Subject Headings], 3',4' -dihidroxifenilglicol, RM1-950, Cardiovascular, Biochemistry, Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus, Type 1 [Medical Subject Headings], Chemicals and Drugs::Biological Factors::Antigens::Antigens, Surface::Cell Adhesion Molecules [Medical Subject Headings], Article, Estrés nitrosativo, Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus, Experimental [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Theoretical [Medical Subject Headings], Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Lipid Peroxidation [Medical Subject Headings], Organisms::Eukaryota::Animals [Medical Subject Headings], Hydroxytyrosol, Molecular Biology, Estrés oxidativo, Cell Biology, Aceite de oliva, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Glycoproteins::Membrane Glycoproteins::Cell Adhesion Molecules::Vascular Cell Adhesion Molecule-1 [Medical Subject Headings], Biomarcadores, Diabetes mellitus tipo 1, Oxidative stress, Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids, Unsaturated::Eicosanoids::Arachidonic Acids::Thromboxanes::Thromboxane B2 [Medical Subject Headings], Therapeutics. Pharmacology, Extra-virgin olive oil polyphenols

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58eae0e7a09c1b5e669c2453bfd1e7f4

المؤلفون: Patricia Perez-García, Ricardo Pardillo-Díaz, Noelia Geribaldi-Doldán, Ricardo Gómez-Oliva, Samuel Domínguez-García, Carmen Castro, Pedro Nunez-Abades, Livia Carrascal

المساهمون: Universidad de Sevilla. Departamento de Fisiología, [Perez-García,P, Nunez-Abades,P, Carrascal,L] Department of Physiology, School of Pharmacy, University of Seville, Seville, Spain. [Perez-García,P, Pardillo-Díaz,R, Gómez-Oliva,R, Domínguez-García,S, Castro,C] Division of Physiology, School of Medicine, University of Cádiz, Cádiz, Spain. [Pardillo-Díaz,R, Geribaldi-Doldán,N, Castro,C, Carrascal,L] Biomedical Research and Innovation Institute of Cádiz (INiBICA), Cádiz, Spain. [Geribaldi-Doldán,N] Department of Human Anatomy and Embriology, University of Cádiz, Cádiz, Spain., This work was partially supported by Spanish Ministerio de Ciencia, Innovación y Universidades (RTI2018-099908-BC21) and co-financed by the 2014–2020 ERDF Operational Programme and by the Department of Economy, Knowledge, Business and University of the Regional Government of Andalusia (FEDER-UCA18-106647)., This work was partially supported by Spanish Ministerio de Ciencia, Innovación y Universidades (RTI2018-099908-B C21) and co-financed by the 2014–2020 ERDF Operational Programme and by the Department of Economy, Knowledge, Business and University of the Regional Government of Andalusia (FEDER-UCA18-106647).

المصدر: Frontiers in Molecular Neuroscience
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Frontiers in Molecular Neuroscience, Vol 14 (2021)

مصطلحات موضوعية: Pyramidal neurons, Células piramidales, Neurosciences. Biological psychiatry. Neuropsychiatry, Membrane properties, Development, Neuronas motoras, Anatomy::Nervous System::Neurons::Pyramidal Cells [Medical Subject Headings], patch clamp, Técnicas de placa-clamp, Cellular and Molecular Neuroscience, motor cortex, Organisms::Eukaryota::Animals [Medical Subject Headings], motor neurons, Desarrollo humano, Phenomena and Processes::Physical Phenomena::Biophysical Phenomena::Membrane Potentials [Medical Subject Headings], Corteza motora, Anatomy::Nervous System::Central Nervous System::Brain::Prosencephalon::Telencephalon::Cerebrum::Cerebral Cortex::Frontal Lobe::Motor Cortex [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals [Medical Subject Headings], development, Molecular Biology, membrane properties, Motor neurons, Original Research, pyramidal neurons, Chemistry, Anatomy::Nervous System::Neurons::Neurons, Efferent::Motor Neurons [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats [Medical Subject Headings], Membrane, Anatomy::Cells::Neurons::Pyramidal Cells [Medical Subject Headings], Motor cortex, Phenomena and Processes::Cell Physiological Phenomena::Membrane Potentials::Action Potentials [Medical Subject Headings], Primary motor cortex, Patch clamp, Layer (electronics), Neuroscience, RC321-571

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9893d6314dd20396497d6df14fc52f8

المؤلفون: M. Gonzalo Claros, Concha Berbel, Manuel Manchado, Juan F. Martinez-Blanch, Jèssica Gómez-Garrido, Israel Guerrero-Cózar, Pierre-Alexandre Gagnaire, Tyler Alioto

المساهمون: Institut des Sciences de l'Evolution de Montpellier (UMR ISEM), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Institut de recherche pour le développement [IRD] : UR226-Centre National de la Recherche Scientifique (CNRS), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre National de la Recherche Scientifique (CNRS)-Institut de recherche pour le développement [IRD] : UR226, Guerrero-Cózar, Israel, Gómez-Garrido, Jèssica, Berbel, Concha, Martinez-Blanch, Juan F., Alioto, Tyler, Claros, M. Gonzalo, Gagnaire, Pierre-Alexandre, Manchado, Manuel, [Guerrero-Cózar,I, Berbel,C, Manchado,M] IFAPA Centro El Toruño, Junta de Andalucía, Puerto de Santa María, Cádiz, Spain. [Gomez-Garrido,J, Alioto,T] CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain. [Martinez-Blanch,JF] Biopolis S.L.-ADM, Parc Cientifc Universidad De Valencia, Paterna, Spain. [Alioto,T] Universitat Pompeu Fabra (UPF), Barcelona, Spain. [Claros,MG] Department of Molecular Biology and Biochemistry, Universidad de Málaga, Málaga, Spain. [Claros,MG] CIBER de Enfermedades Raras (CIBERER), Málaga, Spain. [Claros,MG] Institute of Biomedical Research in Málaga (IBIMA), IBIMA-RARE, Málaga, Spain. [Claros,MG] Instituto de Hortofruticultura Subtropical Y Mediterránea (IHSM-UMA-CSIC), Málaga, Spain. [Gagnaire,PA] ISEM, Univ Montpellier, CNRS, EPHE, IRD, Montpellier, France. [Manchado,M] Crecimiento Azul, Centro IFAPA El Toruño, Unidad Asociada al CSIC, El Puerto de Santa María, Spain., This study was funded by project RTA2017-00054-C03-01 and RTA2017-00054-C03-funded from MCIU/AEI/FEDER, UE and cofunded 80% by Programa Operativo FEDER de Andalucía 2014-2020, project PP.AVA.AVA201601.9 SOLEALGAE. Moreover, the study has received funding from EU H2020 research and innovation program under grant agreement 817992 ERANET-BLUEBIO COFUND project PCI2020-111994 BestBrood/AEI/10.13039/501100011033. IGC is funded by a predoctoral fellowship from INIA. This work would not have been possible without the computer resources and the technical support provided by the Plataforma Andaluza de Bioinformática of the University of Málaga and CNAG. We acknowledge the support of the Spanish Ministry of Science, Innovation and Universities to the EMBL partnership, the Centro de Excelencia Severo Ochoa and the CERCA Programme/Generalitat de Catalunya, the Spanish Ministry of Science and Innovation through the Instituto de Salud Carlos III, Generalitat de Catalunya through Departament de Salut and Departament d’Empresa i Coneixement and co-fnancing with funds from the European Regional Development Fund by the Spanish Ministry of Science and Innovation corresponding to the Programa Operativo FEDER Plurirregional de España (POPE) 2014-2020 and by the Secretaria d’Universitats i Recerca, Departament d’Empresa i Coneixe ment of the Generalitat de Catalunya corresponding to the Programa Operatiu FEDER de Catalunya 2014-20.

المصدر: Scientific Reports
Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-92601-5⟩
Scientific Reports, Nature Publishing Group, 2021, 11 (1), ⟨10.1038/s41598-021-92601-5⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)

مصطلحات موضوعية: Male, Genetic Linkage, Genome-wide association study, Genome, 0302 clinical medicine, Organisms::Eukaryota::Animals [Medical Subject Headings], Diferenciación sexual, Ligamiento genético, Genetics, Gene Rearrangement, 0303 health sciences, Multidisciplinary, Contig, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Fishes::Flatfishes [Medical Subject Headings], [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE], Genomics, Penetrance, Repeticiones de microsatélite, Fatfish, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Base Sequence::Repetitive Sequences, Nucleic Acid::Tandem Repeat Sequences::Microsatellite Repeats [Medical Subject Headings], Flatfishes, Medicine, Sex, Female, Heterogametic sex, Phenomena and Processes::Genetic Phenomena::Genetic Processes::Sex Determination Processes [Medical Subject Headings], Science, Check Tags::Male [Medical Subject Headings], Locus (genetics), Biology, Chromosome, Article, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome [Medical Subject Headings], 03 medical and health sciences, Genetic linkage, Phenomena and Processes::Genetic Phenomena::Genetic Linkage [Medical Subject Headings], Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Rearrangement [Medical Subject Headings], Animals, Genoma, 030304 developmental biology, Animal breeding, Cromosomas, Sex Determination Processes, [SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal genetics, Genes, Check Tags::Female [Medical Subject Headings], 030217 neurology & neurosurgery, Genome-Wide Association Study, Microsatellite Repeats

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document; application/vnd.openxmlformats-officedocument.spreadsheetml.sheet

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91066fd631623356a280d28f166433b9
https://hal.science/hal-03443762

المؤلفون: M. Carmen González-Montelongo, Belén Cuevas, Ana I. Arroba, Laura Gómez-Jaramillo, Eva Zubía, Carolina de los Reyes

المساهمون: [Cuevas,B, de Los Reyes,C, Zubía,E] Departamento de Química Orgánica, Facultad de Ciencias del Mar y Ambientales, Universidad de Cádiz, Puerto Real (Cádiz), Spain. [Cuevas,B, Arroba,AI, Gómez-Jaramillo,L, González-Montelongo,MC] Unidad de Investigación, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), Hospital Universitario Puerta del Mar, Cádiz, Spain. [Arroba,AI] Departamento de Endocrinología y Nutrición, Hospital Universitario Puerta del Mar, Cádiz, Spain., This research was funded by Junta de Andalucía, Spain (ITI-FEDER, research project ITI 0012-2019).

المصدر: Marine Drugs; Volume 19; Issue 12; Pages: 677
Marine Drugs, Vol 19, Iss 677, p 677 (2021)

مصطلحات موضوعية: Rugulopteryx okamurae, medicine.medical_treatment, Pharmaceutical Science, chemistry.chemical_compound, Drug Discovery, cytokine, Organisms::Eukaryota::Animals [Medical Subject Headings], Biology (General), Pharmacology, Toxicology and Pharmaceutics (miscellaneous), anti-inflammatory, chemistry.chemical_classification, biology, Organisms::Organism Forms::Aquatic Organisms [Medical Subject Headings], Organisms::Eukaryota::Stramenopiles::Phaeophyta [Medical Subject Headings], Chemicals and Drugs::Inorganic Chemicals::Free Radicals::Nitric Oxide [Medical Subject Headings], Citocinas, Cytokine, Microglia, Undecane, QH301-705.5, Stereochemistry, medicine.drug_class, Brown algae, Antiinflamatorios, Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Cytokines [Medical Subject Headings], Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Inflammatory Agents [Medical Subject Headings], brown algae, Phaeophyta, Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Structure-Activity Relationship [Medical Subject Headings], Anti-inflammatory, nitric oxide, Anatomy::Cells::Connective Tissue Cells::Macrophages [Medical Subject Headings], medicine, Dictyotaceae, Macrófagos, Anatomy::Cells::Neuroglia::Microglia [Medical Subject Headings], Diterpenoids, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice [Medical Subject Headings], Macrophages, Invasive algae, Diterpenos, diterpenoids, Nitric oxide, biology.organism_classification, Terpenoid, Algas marinas, chemistry, Cell culture, Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Terpenes::Diterpenes [Medical Subject Headings], microglia, macrophages, invasive algae, Óxido nítrico, Tricyclic

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a530bbb7df84f1ab74e8dd49f011af1a

المؤلفون: Antonio Mazzocca, Andrew J. Morris, Sander de Kivit, Apostolos Menegakis, Maaike van Zon, Wouter H. Moolenaar, Ton N. Schumacher, Joost H. van den Berg, Elisa Matas-Rico, Inge Verbrugge, John B. A. G. Haanen, Irene van der Haar Àvila, Telma Lança, Zoë Johnson, Elselien Frijlink, Fernando Salgado-Polo, Jan Koster, Anastassis Perrakis, Jannie Borst

المساهمون: [Matas-Rico,E, Salgado-Polo,F, Perrakis,A, Moolenaar,WH] Division of Biochemistry, Netherlands Cancer Institute, Amsterdam, the Netherlands. [Frijlink,E, van der Haar Àvila,I, de Kivit,S, Verbrugge,I, Borst,J] Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands. [Frijlink,E, Menegakis,A, Lança,T, Schumacher,TN, Borst,J] Oncode Institute, Utrecht, the Netherlands. [Menegakis,A] Division of Cell Biology, Netherlands Cancer Institute, Amsterdam, the Netherlands. [van Zon,M, Haanen,J, van den Berg,JH] Division of Molecular Oncology and Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands. [Morris,AJ] Division of Cardiovascular Medicine, Gill Heart Institute and Lexington Veterans Affairs Medical Center, University of Kentucky, Lexington, KY, USA. [Koster,J] Laboratory for Experimental Oncology and Radiobiology, Amsterdam UMC, Amsterdam, the Netherlands. [Mazzocca,A] Interdisciplinary Department of Medicine, University of Bari School of Medicine, Bari, Italy. [Johnson,Z] Onctura SA, Campus Biotech Innovation Park, Geneva, Switzerland. [Matas-Rico,E] Department of Cell Biology, Genetics and Physiology, Malaga University, Malaga, Spain. [Matas-Rico,E] Genitourinary Cancer Translational Research Group, The Institute of Biomedical Research in Malaga (IBIMA), Malaga, Spain. [van der Haar Àvila,I] Amsterdam UMC, Department of Molecular Cell Biology and Immunology, Amsterdam UMC, Amsterdam, the Netherlands. [de Kivit,S, Borst,J] Department of Immunology, Leiden University Medical Center, Leiden, the Netherlands. [Verbrugge,I] Janssen Pharmaceutica NV, Beerse, Belgium. [van den Berg,JH] CellPoint BV, Oegstgeest, the Netherlands., This work was supported by private funding to W.H.M. and grants from the Dutch Cancer Society (NKI 2013-5951 and 10764 to I.V. and NKI 2017-10894 to J.B. and I.V.), the German Research Foundation (DFG) (ME 4924/1-1 to A. Mazzocca), and the NIH (P30 GM127211 to A.J.M.). E.M.-R. is supported by a ‘‘Ramón y Cajal’’ Award (RYC2019-027950-I) from Ministerio de Ciencia e Innovación (MICINN), Spain., Oncogenomics, AII - Cancer immunology, CCA - Cancer biology and immunology

المصدر: Cell Reports, 37(7). CELL PRESS
Cell reports, 37(7):110013. Cell Press
Cell Reports, Vol 37, Iss 7, Pp 110013-(2021)
Cell reports

مصطلحات موضوعية: autotaxin, Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice::Mice, Inbred Strains::Mice, Inbred C57BL [Medical Subject Headings], medicine.medical_treatment, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Movement::Chemotaxis [Medical Subject Headings], CD8-Positive T-Lymphocytes, Receptores acoplados a proteínas G, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, G-Protein-Coupled::Receptors, Lysophospholipid::Receptors, Lysophosphatidic Acid [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Mice, chemistry.chemical_compound, G protein-coupled receptors, Neoplasms, Lysophosphatidic acid, Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::Lymphocytes, Tumor-Infiltrating [Medical Subject Headings], Organisms::Eukaryota::Animals [Medical Subject Headings], Cytotoxic T cell, Receptors, Lysophosphatidic Acid, Biology (General), Melanoma, Chemistry, Chemotaxis, anti-cancer vaccination, Linfocitos T, Neoplasias, Chemorepulsion, Autotaxin, Tumor microenvironment, single-cell RNAseq, Chemicals and Drugs::Lipids::Membrane Lipids::Phospholipids::Glycerophosphates::Phosphatidic Acids::Lysophospholipids [Medical Subject Headings], Female, immunotherapy, Immunotherapy, Signal Transduction, QH301-705.5, T cells, chemorepulsion, Anti-cancer vaccination, Article, General Biochemistry, Genetics and Molecular Biology, Single-cell RNAseq, Lymphocytes, Tumor-Infiltrating, Células, Microambiente tumoral, Cell Line, Tumor, medicine, melanoma, Animals, Humans, tumor microenvironment, Inmunoterapia, LPAR2, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice [Medical Subject Headings], LPAR1, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Biological Therapy::Immunomodulation::Immunotherapy::Immunization::Immunotherapy, Active::Vaccination [Medical Subject Headings], Phosphoric Diester Hydrolases, Phenomena and Processes::Cell Physiological Phenomena::Cellular Microenvironment::Tumor Microenvironment [Medical Subject Headings], Iysophosphatidic acid, Mice, Inbred C57BL, Cancer research, Lysophospholipids, lysophosphatidic acid, Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::T-Lymphocytes::CD8-Positive T-Lymphocytes [Medical Subject Headings], Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Esterases::Phosphoric Diester Hydrolases [Medical Subject Headings]

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f76b9a7073f697d72868dba203452394
https://doi.org/10.1016/j.celrep.2021.110013

المؤلفون: Ricardo Fernández-Valadés Gámez, Belén Gironés-Camarasa, Antonio España-López, Miguel Alaminos, Cristina Blanco-Elices, Miguel Angel Martin-Piedra, Ricardo Fernández-Valadés, Ingrid Garzón

المساهمون: [Martin-Piedra,MA, Blanco-Elices,C, Garzón,I, Alaminos,M] Tissue Engineering Group, Department of Histology, Faculty of Medicine, University of Granada, Granada, Spain. [Martin-Piedra,MA, Alaminos,M, Fernández-Valadés,R] Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain. [Gironés-Camarasa,B, Fernández-Valadés,R] Division of Pediatric Surgery, University Hospital Virgen de las Nieves, Granada, Spain. [Gironés-Camarasa,B] Doctoral Program in Biomedicine, University of Granada, Granada, Spain. [España-López,A, Fernández-Valadés,R] Craniofacial Malformations and Cleft Lip and Palate Management Unit, University Hospital Virgen de las Nieves, Granada, Spain. [Fernández-Valadés Gámez,R] Division of Oral and Maxillofacial Surgery, San Pedro Hospital, La Rioja, Logroño, Spain., This research was funded by the Spanish Plan Nacional de Investigación Científica, De sarrollo e Innovación Tecnológica (I+D+i), grants FIS PI18/0332, FIS PI18/0331, FIS PI21/0980, and ICI19/00024 (BIOCLEFT), from Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación (co-financed by the European Regional Development Fund (ERDF-FEDER), 'Una manera de hacer Europa', European Union). Supported by grant PI-0442-2019 from the Consejería de Salud y Familias, Junta de Andalucía, Spain.

المصدر: Polymers
Volume 13
Issue 22
Polymers, Vol 13, Iss 3939, p 3939 (2021)
Digibug. Repositorio Institucional de la Universidad de Granada
instname

مصطلحات موضوعية: Polymers and Plastics, Mandíbula, Anatomy::Musculoskeletal System::Cartilage [Medical Subject Headings], Organic chemistry, Mandible, Sustitutos de huesos, Chemicals and Drugs::Carbohydrates::Polysaccharides::Sepharose [Medical Subject Headings], Bone tissue, bone, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Musculoskeletal Physiological Processes::Bone Remodeling::Bone Regeneration [Medical Subject Headings], QD241-441, Tissue engineering, Organisms::Eukaryota::Animals [Medical Subject Headings], Huesos, Chemicals and Drugs::Biomedical and Dental Materials::Biocompatible Materials::Bone Substitutes [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Culture Techniques::Cell Engineering::Tissue Engineering [Medical Subject Headings], Anatomy::Musculoskeletal System::Skeleton::Bone and Bones [Medical Subject Headings], Bone substitutes, biology, Chemistry, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Clinical Laboratory Techniques::Cytological Techniques::Histocytological Preparation Techniques::Staining and Labeling [Medical Subject Headings], Fibrin-agarose, Technology and Food and Beverages::Technology, Industry, and Agriculture::Technology [Medical Subject Headings], Fibrina, Bone regeneration, medicine.anatomical_structure, tissue engineering, Osteocalcin, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Carrier Proteins::Calcium-Binding Proteins::Osteocalcin [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Tomography::Tomography, X-Ray::Tomography, X-Ray Computed [Medical Subject Headings], Article, Chemicals and Drugs::Organic Chemicals::Sulfur Compounds::Phenothiazines::Tolonium Chloride [Medical Subject Headings], fibrin-agarose, mandible, Chemicals and Drugs::Carbohydrates::Polysaccharides::Proteoglycans::Chondroitin Sulfate Proteoglycans::Versicans [Medical Subject Headings], medicine, Regeneration, Enostosis, Regeneración ósea, Bone, Cartilage, Regeneration (biology), General Chemistry, Osteocalcina, Diseases::Animal Diseases::Disease Models, Animal [Medical Subject Headings], regeneration, biology.protein, Ingeniería de tejidos, Biomedical engineering

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe32530b950c1388d810a997d22c1e85

المؤلفون: M. M. Arrebola, José Pedro De La Cruz, Juan Antonio López-Villodres, María Dolores Rodríguez-Pérez, Esther Martín-Aurioles, África Fernández-Prior, José Antonio González-Correa, Alejandra Bermúdez-Oria, María Carmen Ríos

المساهمون: Junta de Andalucía, Ministerio de Economía y Competitividad (España), [Rodríguez-Pérez,MD, De La Cruz,JP, González-Correa,JA] Department of Pharmacology, Faculty of Medicine, Biomedical Research Institute (IBIMA), University of Malaga, Málaga, Spain. [López-Villodres,JA, Ríos,MC] Area of Human Histology, Faculty of Medicine, University of Malaga, Málaga, Spain. [Arrebola,MM] Clinical Laboratory, Clinical Management Unit, Hospital Axarquía, AGSEMA, Málaga, Spain. [Martín-Aurioles,E] Clinical Management Unit La Roca, Distrito Sanitario, AGSEMA, Málaga, Spain. [Fernández-Prior,A, Bermúdez-Oria,A] Department of Food Phytochemistry, Instituto de la Grasa (Spanish National Research Council, CSIC), Seville, Spain., This study was supported in part by the Consejería de Salud. Junta de Andalucía (Spain), Proyectos de Investigación en Salud (Regional Ministry of Health. Junta de Andalucía (Spain), Health Research Projects) (PI-0129-2017) and by Ministerio de Economía y Competitividad (Ministry of Economy and Competitiveness) (Spain), Centro para el Desarrollo Tecnológico Industrial (Center for the Development of Industrial Technology), FEDER Interconecta Pluri-Regional Program (Spain), (PS17173. NUTRADAF, ITC-20161265).

المصدر: Antioxidants, Vol 10, Iss 1783, p 1783 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Antioxidants
Volume 10
Issue 11

مصطلحات موضوعية: Antioxidant, Anatomy::Urogenital System::Urinary Tract::Kidney [Medical Subject Headings], Physiology, Thromboxane, medicine.medical_treatment, Clinical Biochemistry, Pharmacology, Biochemistry, chemistry.chemical_compound, Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Antioxidants [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Theoretical [Medical Subject Headings], Diabetes mellitus, Oral administration, Virgin olive oil, Organisms::Eukaryota::Animals [Medical Subject Headings], Hydroxytyrosol, Phenomena and Processes::Metabolic Phenomena::Metabolism::Oxidative Stress [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Administration Routes::Administration, Oral [Medical Subject Headings], Diabetes, Estrés oxidativo, Eicosanoides, Aceite de oliva, Diseases::Endocrine System Diseases::Diabetes Mellitus::Diabetes Mellitus, Experimental [Medical Subject Headings], Proteinuria, Creatinine, Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Azoles::Imidazoles::Creatinine [Medical Subject Headings], Creatinina, Renal function, RM1-950, Article, Nephropathy, medicine, Diseases::Endocrine System Diseases::Diabetes Mellitus::Diabetes Mellitus, Type 1 [Medical Subject Headings], Molecular Biology, Tromboxanos, Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids, Unsaturated::Eicosanoids [Medical Subject Headings], business.industry, Glomerulosclerosis, Chemicals and Drugs::Organic Chemicals::Nitroso Compounds::Nitrosourea Compounds::Streptozocin [Medical Subject Headings], Cell Biology, medicine.disease, Diseases::Male Urogenital Diseases::Urologic Diseases::Urination Disorders::Proteinuria [Medical Subject Headings], Nefropatías diabéticas, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats [Medical Subject Headings], chemistry, Oxidative stress, Eicosanoids, Therapeutics. Pharmacology, business, Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids, Unsaturated::Eicosanoids::Thromboxanes [Medical Subject Headings]

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::621d70578b783491c830a21005918f08
http://hdl.handle.net/10261/267868

المؤلفون: Sonia Torres-Sanchez, Alejandro Lara-Doña, Esther Berrocoso, Daniel Sanchez-Morillo, Blanca Priego-Torres

المساهمون: Ingeniería en Automática, Electrónica, Arquitectura y Redes de Computadores, Psicología, [Lara-Doña,A, Priego-Torres,B, Sanchez-Morillo,D] Biomedical Engineering and Telemedicine Research Group, Systems and Automation Engineering Area, Department of Automation Engineering, Electronics and Computer Architecture and Networks, Universidad de Cádiz, Cádiz, Spain. [Lara-Doña,A, Torres-Sanchez,S, Berrocoso,E, Sanchez-Morillo,D] Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), Cádiz, Spain. [Torres-Sanchez,S, Berrocoso,E] Neuropsychopharmacology & Psychobiology Research Group, Psychobiology Area, Department of Psychology, Universidad de Cádiz, Cádiz, Spain. [Torres-Sanchez,S, Berrocoso,E] Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain., This study was supported by grants co-financed by the 'Fondo Europeo de Desarrollo Re gional' (FEDER)-UE 'A way to build Europe' from the 'Ministerio de Economía y Competitividad' (MINECO: RTI2018-099778-B-I00), the 'Programa Operativo de Andalucía FEDER, Iniciativa Territo rial Integrada ITI 2014-2020 Consejería Salud, Junta de Andalucía' (PI-0080-2017), the 'Plan Andaluz de Investigación, Desarrollo e Innovación (PAIDI 2020), Consejería de Economía, Conocimiento, Em presas y Universidad, Junta de Andalucía (P20_00958)', the European Union’s Horizon 2020 Research and Innovation Programme under the Marie Sklodowska-Curie grant agreement Nº 955684, the 'In stituto de Investigación e Innovación en Ciencias Biomédicas de Cádiz (LI19/06IN-CO22, IN-CO09, IN-CO07)', the 'Consejería de Economía, Innovación, Ciencia y Empleo de la Junta de Andalucía' (CTS-510 and TIC-212), the 'Centro de Investigación Biomédica en Red de Salud Mental-CIBERSAM' (CB/07/09/0033), and the 'Universidad de Cádiz, contrato predoctoral fpuUCA 2019'.

المصدر: Sensors 2021, 21(21), 7106
Sensors
Volume 21
Issue 21
Sensors (Basel, Switzerland)
RODIN. Repositorio de Objetos de Docencia e Investigación de la Universidad de Cádiz
instname
Sensors, Vol 21, Iss 7106, p 7106 (2021)

مصطلحات موضوعية: Light, Computer science, Image processing, TP1-1185, Biochemistry, Pupil, Article, Analytical Chemistry, Mice, Organisms::Eukaryota::Animals [Medical Subject Headings], Anatomy::Sense Organs::Eye::Anterior Eye Segment::Iris::Pupil [Medical Subject Headings], Animals, Segmentation, Electrical and Electronic Engineering, Pupila, Instrumentation, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice [Medical Subject Headings], Psychiatry and Psychology::Behavior and Behavior Mechanisms::Psychology, Social::Group Processes::Consensus [Medical Subject Headings], business.industry, locus coeruleus, Chemical technology, Aprendizaje profundo, Deep learning, pupil size, pupillometry, deep learning, Pattern recognition, Neurophysiology, Anisocoria, Aprendizaje automático, Atomic and Molecular Physics, and Optics, image processing, Light intensity, machine learning, Test set, Anatomy::Nervous System::Central Nervous System::Brain::Brain Stem::Mesencephalon::Locus Coeruleus [Medical Subject Headings], Procesamiento de imagen asistido por computador, Artificial intelligence, business, Chemicals and Drugs::Biological Factors::Biological Markers::Biomarkers, Pharmacological [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates [Medical Subject Headings], Pupillometry

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4386fc148c9048a00c94f89c760e4d2

المؤلفون: Alvaro Gallego-Martinez, Jose A. Lopez-Escamez, Alba Escalera-Balsera, Andrés Soto-Varela, Marisa Flook, Ismael Aran, Juan Manuel Espinosa-Sanchez

المساهمون: [Flook,M, Escalera-Balsera,A, Gallego-Martinez,A, Espinosa-Sanchez,JM, Lopez-Escamez,JA] Otology & Neurotology Group CTS495, Department of Genomic Medicine, GENYO, Centre for Genomics and Oncological Research, Pfizer University of Granada Andalusian Regional Government, PTS, Granada, Spain. [Flook,M, Lopez-Escamez,JA] Sensorineural Pathology Programme, Centro de Investigación Biomédica en Red en Enfermedades Raras, CIBERER, Madrid, Spain. [Flook,M, Lopez-Escamez,JA] Department of Otolaryngology, Instituto de Investigación Biosanitaria ibs.Granada, Hospital Universitario Virgen de las Nieves, Universidad de Granada, Granada, Spain. [Aran,I] Department of Otolaryngology, Complexo Hospitalario de Pontevedra, Pontevedra, Spain. [Soto-Varela,A] Division of Otoneurology, Department of Otorhinolaryngology, Complexo Hospitalario Universitario, Santiago de Compostela, Spain. [Lopez-Escamez,JA] Division of Otolaryngology, Department of Surgery, University of Granada, Granada, Spain., This work was supported by PI17/1644 grant from ISCIII by FEDER Funds from the EU.MF is funded by F18/00228 grant from ISCIII by FEDER Funds from the EU. AEB is funded by the EU’s Horizon 2020 Research and Innovation Programme, Grant Agreement Number 848261.

المصدر: Biomedicines
Volume 9
Issue 11
Biomedicines, Vol 9, Iss 1530, p 1530 (2021)
Digibug. Repositorio Institucional de la Universidad de Granada
Consorcio Madroño

مصطلحات موضوعية: Phenomena and Processes::Genetic Phenomena::Phenotype [Medical Subject Headings], QH301-705.5, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Base Sequence::Regulatory Sequences, Nucleic Acid [Medical Subject Headings], Bisulfite sequencing, Medicine (miscellaneous), Biology, Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Molecular Structure::Base Sequence::GC Rich Sequence::CpG Islands [Medical Subject Headings], Article, General Biochemistry, Genetics and Molecular Biology, Proinflammatory cytokine, Secuenciación completa del genoma, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], WGBS, Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Methylation [Medical Subject Headings], Organisms::Eukaryota::Animals [Medical Subject Headings], medicine, otorhinolaryngologic diseases, genetics, Epigenetics, Biology (General), Meniere Disease, Diseases::Otorhinolaryngologic Diseases::Ear Diseases::Labyrinth Diseases::Endolymphatic Hydrops::Meniere Disease [Medical Subject Headings], hearing loss, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice [Medical Subject Headings], DNA methylation, Enfermedad de Meniere, Citocinas, Hearing loss, Methylation, Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Nervous System Physiological Phenomena::Membrane Potentials::Synaptic Potentials::Excitatory Postsynaptic Potentials [Medical Subject Headings], medicine.disease, Phenotype, cytokines, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Amino Acids::Amino Acids, Acidic::Aspartic Acid::N-Methylaspartate [Medical Subject Headings], Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Computational Biology [Medical Subject Headings], CpG site, Pérdida auditiva, Meniere disease, Diseases::Otorhinolaryngologic Diseases::Ear Diseases::Hearing Disorders::Hearing Loss [Medical Subject Headings], Cancer research, Cytokines, Sensorineural hearing loss, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Amino Acids::Amino Acids, Acidic::Glutamates [Medical Subject Headings], Metilación de ADN

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.spreadsheetml.sheet; application/vnd.ms-excel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd1b609d1cff4cef353bcb91928f5ba

المؤلفون: del Río, Carmen, Montaner, Joan

المساهمون: [del Río,C, Montaner,J] Institute of Biomedicine of Seville (IBiS), Hospital Universitario Virgen del Rocío, CSIC, Universidad de Sevilla, Seville, Spain. [Montaner,J] Department of Neurology, Hospital Universitario Virgen Macarena, Seville, Spain, The authors received financial support from 'CSF-Proyectos estratégicos de I+D+i. Proyectos cofinanciados en un 80% por fondos del Programa Operativo FEDER de Andalucía 2014–2020', grant number PE-0527-2019. C.R. received financial support from the Juan de la Cierva program funded by the Spanish government, grant number [FJC2018-036897-I].

مصطلحات موضوعية: Cell death, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Cardiovascular Surgical Procedures::Vascular Surgical Procedures::Thrombectomy [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Molecular Targeted Therapy [Medical Subject Headings], Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Protective Agents::Neuroprotective Agents [Medical Subject Headings], Accidente cerebrovascular, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Theoretical [Medical Subject Headings], Ischemia, Organisms::Eukaryota::Animals [Medical Subject Headings], Phenomena and Processes::Biological Phenomena::Species Specificity [Medical Subject Headings], Hipoxia, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Theoretical::Models, Biological [Medical Subject Headings], Anatomy::Nervous System::Neurons [Medical Subject Headings], Hypoxia tolerance, Neuroprotección, Anatomy::Nervous System::Central Nervous System::Brain [Medical Subject Headings], Organisms::Eukaryota::Animals::Invertebrates::Helminths::Nematoda::Secernentea::Rhabditida::Rhabditoidea::Caenorhabditis::Caenorhabditis elegans [Medical Subject Headings], Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death [Medical Subject Headings], Neuroprotection, Muerte celular, Stroke therapy, Stroke, Isquemia, Diseases::Cardiovascular Diseases::Vascular Diseases::Cerebrovascular Disorders::Brain Ischemia [Medical Subject Headings], Diseases::Nervous System Diseases::Central Nervous System Diseases::Brain Diseases::Brain Injuries [Medical Subject Headings], Diseases::Cardiovascular Diseases::Vascular Diseases::Cerebrovascular Disorders::Stroke [Medical Subject Headings], Diseases::Cardiovascular Diseases::Vascular Diseases::Cerebrovascular Disorders::Brain Ischemia::Hypoxia-Ischemia, Brain [Medical Subject Headings], Organisms::Eukaryota::Animals::Invertebrates::Arthropods::Insects::Diptera::Drosophilidae::Drosophila [Medical Subject Headings]

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______2636::ef6664e789bd8ce05cf0839500e3520f
https://hdl.handle.net/10668/4141

المؤلفون: de Oliveira, Jade, Kucharska, Ewa, Garcez, Michelle Lima, Rodrigues, Matheus Scarpatto, Quevedo, João, Moreno-Gonzalez, Ines, Budni, Josiane

المساهمون: [de Oliveira,J, Scarpatto Rodrigues,M] Programa de Pós-Graduação em Ciências Biológicas: Bioquímica, Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.[Kucharska,E] Faculty of Education, Institute of Educational Sciences, Jesuit University Ignatianum in Krakow, Krakow, Poland. [Lima Garcez,M] Department of Biochemistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil. [Quevedo,J] Translational Psychiatry Program, Faillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston. [Quevedo,J] Center of Excellence on Mood Disorders, Faillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth), Houston, USA. [Quevedo,J] Neuroscience Graduate Program, Graduate School of Biomedical Sciences, MD Anderson Cancer Center, UTHealth, The University of Texas Houston, Houston, TX, USA. [Quevedo,J] Graduate Program in Health Sciences, Translational Psychiatry Laboratory, University of Southern Santa Catarina (UNESC), Criciuma, Brazil. [Moreno-Gonzalez,I] Department of Cell Biology, Faculty of Sciences, University of Malaga, IBIMA, Malaga, Spain. [Moreno-Gonzalez,I] Networking Research Center on Neurodegenerative Diseases (CIBERNED), Malaga, Spain. [Moreno-Gonzalez,I] Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth), Houston, USA. [Budni,J] Programa de Pós-Graduação em Ciências da Saúde, Laboratório de Neurologia Experimental, Universidade do Extremo Sul Catarinense, Criciuma, Brazil.

مصطلحات موضوعية: Systemic inflammation, Terapéutica, Anti-inflammatory effects, Neurodegenerative disease, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death [Medical Subject Headings], Enfermedades neurodegenerativas, Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antirheumatic Agents [Medical Subject Headings], Diseases::Animal Diseases::Disease Models, Animal [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Neuroinflammation, Enfermedad de Alzheimer, Demencia, Organisms::Eukaryota::Animals [Medical Subject Headings], Dementia, Diseases::Nervous System Diseases::Central Nervous System Diseases::Brain Diseases::Dementia::Alzheimer Disease [Medical Subject Headings], Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Inflammation::Systemic Inflammatory Response Syndrome [Medical Subject Headings], Therapy, BBB disruption, Síndrome de respuesta inflamatoria sistémica, Alzheimer’s disease, Inflammatory cascade, Persons::Persons::Age Groups::Adult::Aged [Medical Subject Headings]

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______2636::ae6bfbc827c854bbf573adc95cb26ba0
https://hdl.handle.net/10668/3613

المؤلفون: Farouk Rezgui, Sihem Bouriche, E. Fernández-Varón, Angela Alonso-García, Carlos M. Cárceles-Rodríguez

المساهمون: [Bouriche,S, Rezgui,F] Laboratoire des Matériaux Organiques (LMO), Faculté de Technologie, Département de Génie des Procédés, Université de Bejaia, Bejaia, Algeria. [Bouriche,S, Alonso-García,A, Cárceles-Rodríguez,CM] Department of Pharmacology, Faculty of Veterinary Medicine, Universidad de Murcia, Murcia, Spain. [Fernández-Varón,E] Department of Pharmacology, Center for Biomedical Research (CIBM), University of Granada, Granada, Spain. [Fernández-Varón,E] Instituto de Investigación Biosanitaria de Granada (ibs. GRANADA), Granada, Spain., This research was funded by the Government of the Region de Murcia (Spain) by the Fundación Séneca (project 20950/PI/18). The Fundación Séneca had no role in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript.

المصدر: BMC Veterinary Research, Vol 17, Iss 1, Pp 1-11 (2021)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
BMC Veterinary Research

مصطلحات موضوعية: Chemicals and Drugs::Pharmaceutical Preparations::Dosage Forms::Delayed-Action Preparations [Medical Subject Headings], endocrine system diseases, Polymeric-based formulations, Controlled-release, Veterinary medicine, Administration, Oral, Pharmacology, Phenomena and Processes::Metabolic Phenomena::Pharmacokinetics::Biological Availability [Medical Subject Headings], chemistry.chemical_compound, Phenomena and Processes::Chemical Phenomena::Physicochemical Phenomena::Particle Size [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Lagomorpha::Rabbits [Medical Subject Headings], SF600-1100, Organisms::Eukaryota::Animals [Medical Subject Headings], Ácido láctico, Espectroscopía infrarroja por transformada de Fourier, Phenomena and Processes::Chemical Phenomena::Chemical Processes::Physicochemical Processes::Hydrogen Bonding [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Carnivora::Canidae::Dogs [Medical Subject Headings], Biguanide, Preparaciones de acción retardada, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Administration Routes::Administration, Oral [Medical Subject Headings], Lactic acid, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Crystallography::X-Ray Diffraction [Medical Subject Headings], General Medicine, Controlled release, Metformin, Diabetes mellitus tipo 2, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Calorimetry::Calorimetry, Differential Scanning [Medical Subject Headings], Chemicals and Drugs::Macromolecular Substances::Polymers::Polyesters [Medical Subject Headings], Chemicals and Drugs::Organic Chemicals::Amidines::Guanidines::Biguanides::Metformin [Medical Subject Headings], Administration, Intravenous, Rabbits, Research Article, medicine.drug, Half-Life, Semivida, medicine.drug_class, Polyesters, Phenomena and Processes::Physical Phenomena::Time::Half-Life [Medical Subject Headings], Microparticles, Pharmacokinetics, In vivo, medicine, Animals, Rastreo diferencial de calorimetría, Microparticle, Particle Size, Metformina, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Fourier Analysis [Medical Subject Headings], General Veterinary, Calorimetry, differential scanning, Diseases::Endocrine System Diseases::Diabetes Mellitus::Diabetes Mellitus, Type 2 [Medical Subject Headings], nutritional and metabolic diseases, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Spectrum Analysis::Spectrophotometry::Spectrophotometry, Infrared::Spectroscopy, Fourier Transform Infrared [Medical Subject Headings], Chemicals and Drugs::Organic Chemicals::Carboxylic Acids::Hydroxy Acids::Lactates::Lactic Acid [Medical Subject Headings], Microplásticos, Bioavailability, Diabetes Mellitus, Type 2, Farmacocinética, chemistry, Delayed-Action Preparations, Spectroscopy, Fourier transformifrared, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Perissodactyla::Equidae::Horses [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Administration Routes::Administration, Intravenous [Medical Subject Headings]

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33c8e0dcbafca51da59e8227b9839fa
https://hdl.handle.net/10668/18537

المؤلفون: Ahmad Agil, Miguel Navarro-Alarcón, Diego Salagre, Ehab Kotb Elmahallawy, Ashraf Albrakati, Fatma Abo Zakaib Ali, Cristina Campoy

المساهمون: [Agil,A, Salagre,D] Department of Pharmacology and Neurosciences Institute, School of Medicine, University of Granada, Granada, Spain. [Agil,A, Salagre,D, Campoy,C] Biosanitary Research Institute of Granada (ibs.GRANADA), University Hospital of Granada, Granada, Spain. [Navarro-Alarcon,M] Department of Nutrition and Bromatology, School of Pharmacy, University of Granada, Granada, Spain. [Ali,FAZ] Department of Pathology and Clinical Pathology, Faculty of Veterinary Medicine, Sohag University, Sohag, Egypt. [Albrakati,A] Department of Human Anatomy, College of Medicine, Taif University,Taif, Saudi Arabia. [Campoy,C] Department of Pediatric, School of Medicine, University of Granada, Granada, Spain. [Elmahallawy,EK] Department of Zoonoses, Faculty of Veterinary Medicine, Sohag University, Sohag, Egypt., This work was supported by grant SAF2016-79794-R from the Ministerio de Ciencia e Innovación (Spain) and European Regional Development Fund (ERDF).

المصدر: Antioxidants
Volume 10
Issue 9
Antioxidants, Vol 10, Iss 1482, p 1482 (2021)
Digibug. Repositorio Institucional de la Universidad de Granada
instname

مصطلحات موضوعية: medicine.medical_specialty, Physiology, Clinical Biochemistry, Chemicals and Drugs::Carbohydrates::Monosaccharides::Hexoses::Glucose [Medical Subject Headings], Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 2-Ring::Purines::Purine Nucleotides::Adenine Nucleotides::Adenosine Diphosphate [Medical Subject Headings], melatonin, Oxidative phosphorylation, Diabetes Mellitus Tipo 2, RM1-950, Mitochondrion, Brown adipose tissue, Biochemistry, Article, Melatonin, Melatonina, mitochondrial function, Internal medicine, medicine, Organisms::Eukaryota::Animals [Medical Subject Headings], Glucose homeostasis, Molecular Biology, Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Mitochondria [Medical Subject Headings], Roedores, Chemistry, brown adipose tissue, Cell Biology, Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, Brown [Medical Subject Headings], Thermogenin, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Apoptosis [Medical Subject Headings], medicine.anatomical_structure, Endocrinology, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats [Medical Subject Headings], Mitochondrial permeability transition pore, Apoptosis, Mitochondrial function/dynamic, Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus, Type 2 [Medical Subject Headings], Therapeutics. Pharmacology, Mitochondrial function, Tejido adiposo pardo, Phenomena and Processes::Physiological Phenomena::Physiological Processes::Homeostasis [Medical Subject Headings], Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 2-Ring::Purines::Purine Nucleotides::Adenine Nucleotides::Adenosine Triphosphate [Medical Subject Headings], Zücker diabetic fatty rat, medicine.drug

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2dceaae0d8460732d9dff778eef1aaf