المصدر: A Phase 1 and Phase II and Re-Treatment Study of AZD6244 for Recurrent or Refractory Pediatric Low Grade Glioma
Fangusaro J, Onar-Thomas A, Young Poussaint T, Wu S, Ligon AH, Lindeman N, Banerjee A, Packer RJ, Kilburn LB, Goldman S, Pollack IF, Qaddoumi I, Jakacki RI, Fisher PG, Dhall G, Baxter P, Kreissman SG, Stewart CF, Jones DTW, Pfister SM, Vezina G, Stern JS, Panigrahy A, Patay Z, Tamrazi B, Jones JY, Haque SS, Enterline DS, Cha S, Fisher MJ, Doyle LA, Smith M, Dunkel IJ, Fouladi M. Selumetinib in paediatric patients with BRAF-aberrant or neurofibromatosis type 1-associated recurrent, refractory, or progressive low-grade glioma: a multicentre, phase 2 trial. Lancet Oncol. 2019 Jul;20(7):1011-1022. doi: 10.1016/S1470-2045(19)30277-3. Epub 2019 May 28.

المصدر: Natural History Study and Longitudinal Assessment of Children, Adolescents, and Adults With Neurofibromatosis Type 1
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Kim A, Gillespie A, Dombi E, Goodwin A, Goodspeed W, Fox E, Balis FM, Widemann BC. Characteristics of children enrolled in treatment trials for NF1-related plexiform neurofibromas. Neurology. 2009 Oct 20;73(16):1273-9. doi: 10.1212/WNL.0b013e3181bd1326.
Curry BP, Alvarez R, Widemann BC, Johnson M, Agarwal PK, Lehky T, Valera V, Chittiboina P. Robotic Nerve Sheath Tumor Resection With Intraoperative Neuromonitoring: Case Series and Systematic Review. Oper Neurosurg (Hagerstown). 2022 Feb 1;22(2):44-50. doi: 10.1227/ONS.0000000000000051.
Akshintala S, Baldwin A, Liewehr DJ, Goodwin A, Blakeley JO, Gross AM, Steinberg SM, Dombi E, Widemann BC. Longitudinal evaluation of peripheral nerve sheath tumors in neurofibromatosis type 1: growth analysis of plexiform neurofibromas and distinct nodular lesions. Neuro Oncol. 2020 Sep 29;22(9):1368-1378. doi: 10.1093/neuonc/noaa053.
Dagalakis U, Lodish M, Dombi E, Sinaii N, Sabo J, Baldwin A, Steinberg SM, Stratakis CA, Widemann BC. Puberty and plexiform neurofibroma tumor growth in patients with neurofibromatosis type I. J Pediatr. 2014 Mar;164(3):620-4. doi: 10.1016/j.jpeds.2013.10.081. Epub 2013 Dec 8.

المؤلفون: University Medical Center Groningen, HollandPTC, Erasmus Medical Center, Leiden University Medical Center, Medical Center Haaglanden, Maastro Clinic, The Netherlands

المصدر: Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncology

المصدر: A Pilot Study of Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors
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المساهمون: Junping Zhang, Chief physician

المصدر: Clinical Study of Modified Carboplatin/vincristine Chemotherapy Regimen for Visual Function Protection in Children with Optic Pathway Gliomas

المؤلفون: Janssen Pharmaceuticals

المساهمون: Julie Krystal, Head, Developmental Therapeutics

المصدر: A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas
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المؤلفون: AstraZeneca

المصدر: A Paediatric Phase I/II Study Of Intermittent Dosing Of The Mek-1 Inhibitor Selumetinib In Children With Neurofibromatosis Type-1 And Inoperable Plexiform Neurofibroma And/Or Progressive Optic Pathway Glioma
Dombi E, Baldwin A, Marcus LJ, Fisher MJ, Weiss B, Kim A, Whitcomb P, Martin S, Aschbacher-Smith LE, Rizvi TA, Wu J, Ershler R, Wolters P, Therrien J, Glod J, Belasco JB, Schorry E, Brofferio A, Starosta AJ, Gillespie A, Doyle AL, Ratner N, Widemann BC. Activity of Selumetinib in Neurofibromatosis Type 1-Related Plexiform Neurofibromas. N Engl J Med. 2016 Dec 29;375(26):2550-2560. doi: 10.1056/NEJMoa1605943.
Banerjee A, Jakacki RI, Onar-Thomas A, Wu S, Nicolaides T, Young Poussaint T, Fangusaro J, Phillips J, Perry A, Turner D, Prados M, Packer RJ, Qaddoumi I, Gururangan S, Pollack IF, Goldman S, Doyle LA, Stewart CF, Boyett JM, Kun LE, Fouladi M. A phase I trial of the MEK inhibitor selumetinib (AZD6244) in pediatric patients with recurrent or refractory low-grade glioma: a Pediatric Brain Tumor Consortium (PBTC) study. Neuro Oncol. 2017 Aug 1;19(8):1135-1144. doi: 10.1093/neuonc/now282.

المساهمون: Benedetto Falsini, Professor

المصدر: Safety and Efficacy of Multiple Doses of the PAINLESS Nerve Growth Factor CHF6467 in Paediatric Subjects With Optic Pathway Glioma (OPG). A Randomized Clinical Trial (RCT)
Falsini B, Chiaretti A, Rizzo D, Piccardi M, Ruggiero A, Manni L, Soligo M, Dickmann A, Federici M, Salerni A, Timelli L, Guglielmi G, Lazzareschi I, Caldarelli M, Galli-Resta L, Colosimo C, Riccardi R. Nerve growth factor improves visual loss in childhood optic gliomas: a randomized, double-blind, phase II clinical trial. Brain. 2016 Feb;139(Pt 2):404-14. doi: 10.1093/brain/awv366. Epub 2016 Jan 14.
Falsini B, Chiaretti A, Barone G, Piccardi M, Pierri F, Colosimo C, Lazzareschi I, Ruggiero A, Parisi V, Fadda A, Balestrazzi E, Riccardi R. Topical nerve growth factor as a visual rescue strategy in pediatric optic gliomas: a pilot study including electrophysiology. Neurorehabil Neural Repair. 2011 Jul-Aug;25(6):512-20. doi: 10.1177/1545968310397201. Epub 2011 Mar 26.
Chiaretti A, Falsini B, Servidei S, Marangoni D, Pierri F, Riccardi R. Nerve growth factor eye drop administration improves visual function in a patient with optic glioma. Neurorehabil Neural Repair. 2011 May;25(4):386-90. doi: 10.1177/1545968310395601. Epub 2011 Feb 22.
Abed E, Corbo G, Falsini B. Neurotrophin family members as neuroprotectants in retinal degenerations. BioDrugs. 2015 Feb;29(1):1-13. doi: 10.1007/s40259-014-0110-5.

المصدر: Pilot Study of the MEK1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) for Adults With Neurofibromatosis Type 1 (NF1) and Cutaneous Neurofibromas (CNF)

المؤلفون: Charnock, Lauren, Jukier, Tom, Shaw, Gillian, Kramer, Alana, Brinker, Emily, Moore, Phillip

المصدر: The Canadian veterinary journal. La revue veterinaire canadienne. 64(8)

مصطلحات موضوعية: Animals, Dogs, Optic Nerve Glioma, Hyphema, Margins of Excision, Optic Nerve, Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy, Glaucoma, Dog Diseases

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4t04q670
https://escholarship.org/content/qt4t04q670/qt4t04q670.pdf

المصدر: A Phase 1 Study of Entinostat, an Oral Histone Deacetylase Inhibitor, in Pediatric Patients With Recurrent or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

المؤلفون: R Sharanya, Virna M. Shah, Rajkumar Ramasamy, Karthik Kumar Mani

المصدر: TNOA Journal of Ophthalmic Science and Research, Vol 62, Iss 2, Pp 244-246 (2024)

مصطلحات موضوعية: bitemporal hemianopia, humphrey field analyser, magnetic resonance imaging, optic nerve glioma, suprasellar mass lesion, visual field defects, Ophthalmology, RE1-994

وصف الملف: electronic resource

Relation: https://journals.lww.com/tnoa/fulltext/2024/04000/sporadic_optic_nerve_glioma_causing_bitemporal.21.aspx; https://doaj.org/toc/2589-4528; https://doaj.org/toc/2589-4536

URL الوصول: https://doaj.org/article/82b823630b134a45948754805b8d1781

المؤلفون: Rushil Sharma, MD

المصدر: Radiology Case Reports, Vol 19, Iss 1, Pp 190-199 (2024)

مصطلحات موضوعية: Cavernous malformations, Optic nerve, Prechiasmatic optic nerve, Optic nerve glioma, Chiasm, Medical physics. Medical radiology. Nuclear medicine, R895-920

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1930043323006611; https://doaj.org/toc/1930-0433

URL الوصول: https://doaj.org/article/653b70bbd7354c6f8cd46ef4087489c0

المؤلفون: Pan, Yuan, Hysinger, Jared D, Barron, Tara, Schindler, Nicki F, Cobb, Olivia, Guo, Xiaofan, Yalçın, Belgin, Anastasaki, Corina, Mulinyawe, Sara B, Ponnuswami, Anitha, Scheaffer, Suzanne, Ma, Yu, Chang, Kun-Che, Xia, Xin, Toonen, Joseph A, Lennon, James J, Gibson, Erin M, Huguenard, John R, Liau, Linda M, Goldberg, Jeffrey L, Monje, Michelle, Gutmann, David H

المصدر: Nature. 594(7862)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Cancer, Neurofibromatosis, Brain Cancer, Pediatric, Rare Diseases, Neurosciences, Eye Disease and Disorders of Vision, Genetics, Brain Disorders, 2.1 Biological and endogenous factors, Animals, Astrocytoma, Cell Adhesion Molecules, Neuronal, Cell Transformation, Neoplastic, Female, Genes, Neurofibromatosis 1, Germ-Line Mutation, Humans, Male, Membrane Proteins, Mice, Mutation, Nerve Tissue Proteins, Neurofibromin 1, Neurons, Optic Nerve, Optic Nerve Glioma, Photic Stimulation, Retina, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1h39417j
https://escholarship.org/content/qt1h39417j/qt1h39417j.pdf

المؤلفون: CURE Childhood Cancer, Inc.

المساهمون: Dolly Aguilera, Assistant Professor

المصدر: A Phase II Study Of Pegylated Interferon ALFA-2b in Children With Recurrent or Refractory and Radiographically or Clinically Progressive Juvenile Pilocytic Astrocytomas and Optic Pathway Gliomas

المؤلفون: Bennebroek, Carlien A., Montauban van Swijndregt, Maartje C., van Zwol, Judith, Bhusal, Sanjhana, Dittrich, Anne T., Oostenbrink, Rianne, Pott, Jan Willem R., Buijs, Erik A., Schouten-van Meeteren, Antoinette Y., Porro, Giorgio L., de Graaf, Pim, Saeed, Peerooz

المصدر: Bennebroek , C A , Montauban van Swijndregt , M C , van Zwol , J , Bhusal , S , Dittrich , A T , Oostenbrink , R , Pott , J W R , Buijs , E A , Schouten-van Meeteren , A Y , Porro , G L , de Graaf , P & Saeed , P 2024 , ' Treatment of isolated pediatric optic nerve glioma : A nationwide retrospective cohort study and systematic literature review on visual and radiological outcome ' , Pediatric Blood and Cancer , vol. 71 , no. 12 , e31358 ....

مصطلحات موضوعية: children, low grade glioma, MRI, optic nerve glioma, response assessment, visual function

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/d1de7195-965c-4bbc-89fd-3af46b4b0007
https://research.rug.nl/en/publications/d1de7195-965c-4bbc-89fd-3af46b4b0007
https://doi.org/10.1002/pbc.31358
https://pure.rug.nl/ws/files/1143318501/Pediatric_Blood_Cancer_-_2024_-_Bennebroek_-_Treatment_of_isolated_pediatric_optic_nerve_glioma_A_nationwide.pdf
http://www.scopus.com/inward/record.url?scp=85205893801&partnerID=8YFLogxK

المؤلفون: Peñaloza Barrios, Natalia, Ortiz Roncallo, Lina Marcela, Posso Escobar, Andres Mauricio, Díaz Burgos, Stefany del Carmen, Rincon Molano, Miguel Angel, Yepes Sarmiento, Aura Patricia, Ramos Zamora, Sebastian

المصدر: Ciencia Latina Revista Científica Multidisciplinar; Vol. 8 Núm. 1 (2024); 763-773 ; 2707-2215 ; 2707-2207 ; 10.37811/cl_rcm.v8i1

مصطلحات موضوعية: optic nerve glioma, nf-1, neurofibromatosis, brain tumors, nervio óptico glioma, tumores cerebrales

وصف الملف: application/pdf; text/html

Relation: https://ciencialatina.org/index.php/cienciala/article/view/9456/14026; https://ciencialatina.org/index.php/cienciala/article/view/9456/14027; https://ciencialatina.org/index.php/cienciala/article/view/9456

الاتاحة: https://ciencialatina.org/index.php/cienciala/article/view/9456
https://doi.org/10.37811/cl_rcm.v8i1.9456

المؤلفون: Prathibha Shanthaveerappa, Nithisha Tegginamatha, Neethu Narayan Rao, Suyog Ajjampur Suryaprakash

المصدر: Kerala Journal of Ophthalmology, Vol 35, Iss 3, Pp 284-288 (2023)

مصطلحات موضوعية: lisch nodules, nf1, optic nerve glioma, plexiform neurofibroma, Ophthalmology, RE1-994

وصف الملف: electronic resource

Relation: http://www.kjophthal.com/article.asp?issn=0976-6677;year=2023;volume=35;issue=3;spage=284;epage=288;aulast=Shanthaveerappa; https://doaj.org/toc/0976-6677

URL الوصول: https://doaj.org/article/b9bdbc0e46bf47d8840aec15acc34a1c

المؤلفون: Xiaoning Lin, Rong Huang, Jinyun Su, Heng Li, Zhong Liu, Pengfei Zhang, Xinhua Tian

المصدر: All Life, Vol 15, Iss 1, Pp 262-269 (2022)

مصطلحات موضوعية: optic nerve glioma, adults, prognosis, adjuvant therapy, seer, Biotechnology, TP248.13-248.65, Life, QH501-531

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2689-5307

URL الوصول: https://doaj.org/article/94f344f3651d4d44939f8947c8b1bd21

المصدر: Pilot Study of [18F] Fluorodeoxyglucose Positron Emission Tomography- Magnetic Resonance Imaging (FDG-PET-MRI) in CNS and Extra-CNS Tumors of Patients With Neurofibromatosis-1 (NF1)