المؤلفون: Turner, Matthew, Anderson, David E, Bartels, Peter, Nieves‐Cintron, Madeline, Coleman, Andrea M, Henderson, Peter B, Man, Kwun Nok Mimi, Tseng, Pang‐Yen, Yarov‐Yarovoy, Vladimir, Bers, Donald M, Navedo, Manuel F, Horne, Mary C, Ames, James B, Hell, Johannes W

المصدر: The EMBO Journal. 39(5)

مصطلحات موضوعية: Medical Physiology, Biomedical and Clinical Sciences, Actinin, Amino Acid Substitution, Calcium, Calcium Channels, L-Type, Calmodulin, Humans, Mutation, Neurons, Protein Binding, calmodulin, gating charge, IQ motif structure, open probability, surface expression, Biological Sciences, Information and Computing Sciences, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9jk7j0kq
https://escholarship.org/content/qt9jk7j0kq/qt9jk7j0kq.pdf

المؤلفون: Augustinas Dainys, Linas Jašinauskas

المصدر: Problemos, Vol 103 (2023)

مصطلحات موضوعية: Artificial Intelligence, Algorithm, Bayes' Theorem, Open Probability, Philosophy (General), B1-5802

وصف الملف: electronic resource

Relation: https://zurnalai.vu.lt/problemos/article/view/30559; https://doaj.org/toc/1392-1126; https://doaj.org/toc/2424-6158

URL الوصول: https://doaj.org/article/7435c127b6cf4e61bbb9f9583389ed2d

المؤلفون: Bergh, Cathrine, Heusser, Stephanie A., Howard, Rebecca, Lindahl, Erik

المصدر: Bergh , C , Heusser , S A , Howard , R & Lindahl , E 2021 , ' Markov state models of proton- and pore-dependent activation in a pentameric ligand-gated ion channel ' , eLife , vol. 10 , 68369 . https://doi.org/10.7554/eLife.68369

مصطلحات موضوعية: ligand-gated ion channel, gating, allosteric modulation, molecular dynamics, electrophysiology, markov state model, Xenopus, ACETYLCHOLINE-RECEPTOR, MOLECULAR-DYNAMICS, OPEN PROBABILITY, CONFORMATIONAL TRANSITIONS, GLOEOBACTER-VIOLACEUS, NICOTINIC RECEPTOR, KINETIC-PROPERTIES, STRUCTURAL BASIS, MECHANISM, DESENSITIZATION

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/markov-state-models-of-proton-and-poredependent-activation-in-a-pentameric-ligandgated-ion-channel(8c68da13-84b8-4137-b1c7-04f56cb4a397).html
https://doi.org/10.7554/eLife.68369
https://curis.ku.dk/ws/files/288270347/elife_68369_v1.pdf

المؤلفون: Lycksell, Marie, Rovsnik, Urska, Bergh, Cathrine, Johansen, Nicolai T., Martel, Anne, Porcar, Lionel, Arleth, Lise, Howard, Rebecca J., Lindahl, Erik

المصدر: Lycksell , M , Rovsnik , U , Bergh , C , Johansen , N T , Martel , A , Porcar , L , Arleth , L , Howard , R J & Lindahl , E 2021 , ' Probing solution structure of the pentameric ligand-gated ion channel GLIC by small-angle neutron scattering ' , Proceedings of the National Academy of Sciences of the United States of America , vol. 118 , no. 37 , 2108006118 . https://doi.org/10.1073/pnas.2108006118

مصطلحات موضوعية: Cys-loop receptors, gating, small-angle neutron scattering, molecular dynamics, deuterated detergent, X-RAY-STRUCTURE, ACETYLCHOLINE-RECEPTOR, GLOEOBACTER-VIOLACEUS, MEMBRANE-PROTEINS, OPEN PROBABILITY, OPEN STATE, SEC-SANS, MECHANISM, PORE, CONFORMATION

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/probing-solution-structure-of-the-pentameric-ligandgated-ion-channel-glic-by-smallangle-neutron-scattering(c1ec4fb0-6f38-4e62-97b7-ad68ab9b5e66).html
https://doi.org/10.1073/pnas.2108006118
https://curis.ku.dk/ws/files/302068524/pnas.2108006118.pdf

المؤلفون: Matthew S. Scarnati, Stephen G. Clarke, Zhiping P. Pang, Kenneth G. Paradiso

المصدر: Frontiers in Synaptic Neuroscience, Vol 12 (2020)

مصطلحات موضوعية: action potential, calcium channels, local calcium concentration, nanodomains, microdomains, open probability, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fnsyn.2020.00017/full; https://doaj.org/toc/1663-3563

URL الوصول: https://doaj.org/article/29ad9f2c1cd045e1998b1c5e2668594c

المؤلفون: Pippel, Anja, Stolz, Michaela, Woltersdorf, Ronja, Kless, Achim, Schmalzing, Günther, Markwardt, Fritz

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2017 Mar . 114(11), E2156-E2165.

URL الوصول: https://www.jstor.org/stable/26480292

المؤلفون: Marek Ladislav, Jiri Cerny, Jan Krusek, Martin Horak, Ales Balik, Ladislav Vyklicky

المصدر: Frontiers in Molecular Neuroscience, Vol 11 (2018)

مصطلحات موضوعية: glutamate receptor gating, electrophysiology, spontaneous activity, channel open probability, protein block alphabet, molecular modeling, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fnmol.2018.00113/full; https://doaj.org/toc/1662-5099

URL الوصول: https://doaj.org/article/b7fdc504c10241d1aa8988326b94064a

المؤلفون: Meimi Zhao, Rui Feng, Dongxue Shao, Shuyuan Liu, Ming Lei, Hongmei Wang, Xuefei Sun, Feng Guo, Huiyuan Hu, Masaki Kameyama, Liying Hao

المصدر: Journal of Pharmacological Sciences, Vol 129, Iss 3, Pp 143-149 (2015)

مصطلحات موضوعية: Mg2+, Ca2+ channels, Open probability, Open time, Inside-out configuration, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1347861315001723; https://doaj.org/toc/1347-8613

URL الوصول: https://doaj.org/article/cdbe2d1cba1a42c18af7429e014154e5

المؤلفون: Anna Moroni, Andrea Saponaro, Gerhard Thiel

المصدر: Biochemical Society Transactions. 49:2573-2579

مصطلحات موضوعية: Gene isoform, Chemistry, Cell Membrane, Gating, Biochemistry, Open probability, Structure-Activity Relationship, Cytosol, Voltage sensor, Cyclic AMP, Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels, Biophysics, Animals, CAMP binding, Coordination site, Linker, Signal Transduction, Communication channel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e739cca52a7e8e8fb678c6721612f4f
https://doi.org/10.1042/bst20210290

المؤلفون: Ekrem Aydiner

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
Scientific Reports

مصطلحات موضوعية: Multidisciplinary, Diffusion equation, Science, Time evolution, Markov process, Kinetic energy, Article, Open probability, symbols.namesake, Kinetic equations, Path integral formulation, Master equation, symbols, Medicine, Statistical physics, Statistical physics, thermodynamics and nonlinear dynamics, Biological physics, Mathematics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::719f92f22b9affaf227ba824ec7243e5
https://doaj.org/article/92d027a43438407487b4c19eab7c0df2

المؤلفون: Adrian Kotevski, Kate Poole, Jessica Richardson

المصدر: The FEBS Journal. 289:4447-4469

مصطلحات موضوعية: Mammals, 0301 basic medicine, Ion Transport, Chemistry, PIEZO1, Context (language use), Cell Biology, Mechanotransduction, Cellular, Biochemistry, Ion Channels, Open probability, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Deflection (physics), Modulation, 030220 oncology & carcinogenesis, Biophysics, Animals, Mechanotransduction, Molecular Biology, Ion channel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97f1d7b82352cf2d232afb48d9568cba
https://doi.org/10.1111/febs.16041

المؤلفون: Lascano, Elena Catalina, Negroni, Jorge Antonio, Vila Petroff, Martín Gerardo, Mattiazzi, Alicia Ramona

مصطلحات موضوعية: Ciencias Médicas, Contractility, Heart, Open probability, Ryanodine receptor

وصف الملف: application/pdf; H1105-H1109

Relation: http://sedici.unlp.edu.ar/handle/10915/87547

الاتاحة: http://sedici.unlp.edu.ar/handle/10915/87547

المؤلفون: Rossana G. Iannitti, Bernard Fioretti, Federica Bastioli, Andrea Astolfi, Lorenzo Monarca, Loretta Mancinelli, Francesco Ragonese, Giuseppe Manfroni, Maria Letizia Barreca, Violetta Cecchetti

المصدر: Current Pharmaceutical Design. 26:2096-2101

مصطلحات موضوعية: Pharmacology, 0303 health sciences, Binding Sites, Drug discovery, chemistry.chemical_element, Calcium, Intermediate-Conductance Calcium-Activated Potassium Channels, Potassium channel, Open probability, 03 medical and health sciences, 0302 clinical medicine, chemistry, Modulation, Drug Discovery, Biophysics, Humans, Calcium Signaling, Channel modulation, 030217 neurology & neurosurgery, 030304 developmental biology, Calcium signaling, Communication channel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca9d7bb478221079e0302d4f7ffc59f
https://doi.org/10.2174/1381612826666200316152645

المؤلفون: Dong-Hoon Choi, Peter C. Searson, Grant Kitchen, Kerry J. Stewart

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports

مصطلحات موضوعية: Adult, Male, Adolescent, Physiology, Sweat chloride, lcsh:Medicine, Biosensing Techniques, Article, Open probability, SWEAT, 03 medical and health sciences, Wearable Electronic Devices, Young Adult, 0302 clinical medicine, Animal science, Chlorides, Humans, Sweat, lcsh:Science, Exercise, Multidisciplinary, integumentary system, Chemistry, lcsh:R, Healthy subjects, 030229 sport sciences, Female, lcsh:Q, sense organs, Wearable Electronic Device, Biomedical engineering, Analytical chemistry, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65976035abca00b6f35093f42ced1e6e
http://link.springer.com/article/10.1038/s41598-020-64406-5

المؤلفون: Joyce Keung, Wei Li, Stephen C. Massey, James Carroll, Munenori Ishibashi, Joshua H. Singer, Christophe P. Ribelayga, Li Jia, Sue A. Aicher, Catherine W. Morgans, Iris Fahrenfort

المصدر: eLife. 11

مصطلحات موضوعية: Materials science, genetic structures, Molecular physics, Connexins, Ion Channels, Retina, General Biochemistry, Genetics and Molecular Biology, Open probability, law.invention, Mice, Confocal microscopy, law, Retinal Rod Photoreceptor Cells, Animals, Gap junction protein, General Immunology and Microbiology, General Neuroscience, Gap junction, Gap Junctions, General Medicine, Rod spherule, Coupling (electronics), Cone (topology), Retinal Cone Photoreceptor Cells, sense organs, Electron microscope, Photoreceptor Cells, Vertebrate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0b95bcb6007a4c6d1d018f553f93294
https://doi.org/10.7554/elife.73039

المؤلفون: Hu, Zhenyu, Zhang, Bo, Lim, Leon Jian Ying, Loh, Wei Zhern Kelvin, Yu, Dejie, Tan, Bryce Wei Quan, Liang, Mui Cheng, Huang, Zhongwei, Leo, Chen Huei, Huang, Hua, Soong, Tuck Wah

المساهمون: OBSTETRICS & GYNAECOLOGY, PHYSIOLOGY

المصدر: Elements

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Peripheral Vascular Disease, Cardiovascular System & Cardiology, Ca(V)1, 2 channel, hypertension, lysosome, open probability, S-nitrosylation, SOLUBLE GUANYLATE-CYCLASE, CALCIUM-CHANNELS, ANGIOTENSIN-II, PROTEIN-KINASE, IN-VITRO, INHIBITION, CONTRACTION, RELAXATION, MECHANISM

Relation: Hu, Zhenyu, Zhang, Bo, Lim, Leon Jian Ying, Loh, Wei Zhern Kelvin, Yu, Dejie, Tan, Bryce Wei Quan, Liang, Mui Cheng, Huang, Zhongwei, Leo, Chen Huei, Huang, Hua, Soong, Tuck Wah (2022-12-01). S-Nitrosylation-Mediated Reduction of Ca(V)1.2 Surface Expression and Open Probability Underlies Attenuated Vasoconstriction Induced by Nitric Oxide. HYPERTENSION 79 (12) : 2854-2866. ScholarBank@NUS Repository. https://doi.org/10.1161/HYPERTENSIONAHA.122.19103; https://scholarbank.nus.edu.sg/handle/10635/237717

الاتاحة: https://scholarbank.nus.edu.sg/handle/10635/237717

المؤلفون: Zbigniew Burdach, Agnieszka Siemieniuk, Waldemar Karcz

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12621
International Journal of Molecular Sciences, Vol 22, Iss 12621, p 12621 (2021)
International Journal of Molecular Sciences

مصطلحات موضوعية: Patch-Clamp Techniques, Potassium Channels, PbCl2, QH301-705.5, Taproot, Vacuole, Article, Catalysis, Open probability, Inorganic Chemistry, Cytosol, Gene Expression Regulation, Plant, Beta vulgaris L, Patch clamp, Biology (General), Physical and Theoretical Chemistry, Beta (finance), QD1-999, Molecular Biology, Spectroscopy, Plant Proteins, FV and SV channels, vacuole, Chemistry, Organic Chemistry, Conductance, General Medicine, patch-clamp, Plant cell, Computer Science Applications, Lead, Vacuoles, Biophysics, Beta vulgaris

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3142a5dd66a531bcbe78358e05c0ab4c

المؤلفون: Amanda H. Lewis, Jörg Grandl

المصدر: eLife, Vol 10 (2021)
eLife

مصطلحات موضوعية: Cell type, Work (thermodynamics), Patch-Clamp Techniques, Materials science, QH301-705.5, Structural Biology and Molecular Biophysics, cooperativity, Science, Mechanotransduction, Cellular, Ion Channels, General Biochemistry, Genetics and Molecular Biology, Cell Line, Open probability, Ion, Mice, None, Animals, Humans, force-gated ion channel, Biology (General), Mechanotransduction, Ion channel, mechanotransduction, General Immunology and Microbiology, Chemistry, General Neuroscience, PIEZO1, General Medicine, Sense (electronics), Piezo1, Electrophysiology, Membrane, Structural biology, Membrane curvature, Biophysics, Medicine, Electric current, Function (biology), Research Article, Neuroscience, clustering

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6c88e14077fcae328abcc94f5ca1a26
https://doi.org/10.7554/elife.70988

المؤلفون: Bernd Weiß, Arie Kapteyn, Marcel Das, Michael Bosnjak, Ines Schaurer

المصدر: Wiley StatsRef: Statistics Reference

مصطلحات موضوعية: Open science, Computer science, Calculus, Open probability

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f783aa509dd3b83fc28b8b07d50b89f6
https://doi.org/10.1002/9781118445112.stat07988

المؤلفون: Ikhyun Jun, Min Goo Lee, Jinsei Jung, Jihoon G. Yoon, Mary Hongying Cheng, Yonjung Kim, David C. Whitcomb, He Piao, Dong Hoon Shin, Hyun Woo Park, Ivet Bahar

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 1, Pp 79-103 (2020)

مصطلحات موضوعية: IBMX, 3-isobutyl-1-methylxanthine, 0301 basic medicine, Patch-Clamp Techniques, Cystic Fibrosis, Cystic Fibrosis Transmembrane Conductance Regulator, Po, open probability, Erev, reversal potential, Crystallography, X-Ray, Cystic fibrosis, GST, glutathione S-transferase, OSR1, oxidative stress-responsive kinase 1, 0302 clinical medicine, WNK Lysine-Deficient Protein Kinase 1, PRD, proline-rich domain, WNK1, with-no-lysine kinase 1, Bicarbonate Secretion, Original Research, GFP, green fluorescent protein, NL, N-linker, biology, Kinase, Chemistry, Gastroenterology, respiratory system, WNK1, MD, molecular dynamics, Recombinant Proteins, Cystic fibrosis transmembrane conductance regulator, I-V, current-voltage, 3. Good health, Cell biology, 030211 gastroenterology & hepatology, Epithelia, Intracellular, congenital, hereditary, and neonatal diseases and abnormalities, SDS, sodium dodecyl sulfate, Molecular Dynamics Simulation, Protein Serine-Threonine Kinases, 03 medical and health sciences, Chlorides, Protein Domains, NMDG, N-methyl-D-glucamine, medicine, Ion Selectivity, Humans, CFTR, cystic fibrosis transmembrane conductance regulator, Secretion, Patch clamp, lcsh:RC799-869, Sequence Homology, Amino Acid, Hepatology, PHCO3/PCl, HCO3-/Cl– permeability ratio, medicine.disease, NKCC, Na+-K+-Cl− cotransporter, SPAK, STE20/SPS1-related proline/alanine-rich kinase, WT, wild-type, digestive system diseases, HCO3−, bicarbonate, respiratory tract diseases, Bicarbonates, HEK293 Cells, 030104 developmental biology, Pancreatitis, Protein kinase domain, siRNA, small interfering RNA, Mutation, biology.protein, lcsh:Diseases of the digestive system. Gastroenterology, PKA, protein kinase A, STE20, sterile 20

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d6d71dc3c3dabf11326ade2796975a
https://doi.org/10.1016/j.jcmgh.2019.09.003