المؤلفون: Oblak, Adrian L, Cope, Zackary A, Quinney, Sara K, Pandey, Ravi S, Biesdorf, Carla, Masters, Andi R, Onos, Kristen D, Haynes, Leslie, Keezer, Kelly J, Meyer, Jill A, Peters, Jonathan S, Persohn, Scott A, Bedwell, Amanda A, Eldridge, Kierra, Speedy, Rachael, Little, Gabriela, Williams, Sean‐Paul, Noarbe, Brenda, Obenaus, Andre, Sasner, Michael, Howell, Gareth R, Carter, Gregory W, Williams, Harriet, Lamb, Bruce T, Territo, Paul R, Rizzo, Stacey J Sukoff

المصدر: Alzheimer's & Dementia: Translational Research & Clinical Interventions. 8(1)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Biological Psychology, Clinical Sciences, Psychology, Pharmacology and Pharmaceutical Sciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Alzheimer's Disease, Biomedical Imaging, Neurosciences, Brain Disorders, Dementia, Neurodegenerative, Aging, Acquired Cognitive Impairment, Prevention, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Neurological, amyloid, BACE inhibitor, MODEL-AD, mouse model, preclinical testing, MODEL‐AD, Clinical sciences, Biological psychology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/08m5g6f5

المؤلفون: Onos, Kristen D, Lin, Peter B, Pandey, Ravi S, Persohn, Scott A, Burton, Charles P, Miner, Ethan W, Eldridge, Kierra, Kanyinda, Jonathan Nyandu, Foley, Kate E, Carter, Gregory W, Howell, Gareth R, Territo, Paul R

المصدر: Faculty Research 2024

مصطلحات موضوعية: JGM, JMG, SS1, Animals, Female, Male, Mice, Alzheimer Disease, Apolipoprotein E4, Apolipoproteins E, Brain, Disease Models, Animal, Disease Progression, Glucose, Inbred C57BL, Transgenic, Neurovascular Coupling, Positron-Emission Tomography

وصف الملف: application/pdf

Relation: https://mouseion.jax.org/stfb2024/212; https://mouseion.jax.org/context/stfb2024/article/1177/viewcontent/Alzheimer_s_Dementia___2024___Onos___Assessment_of_neurovascular_uncoupling_APOE_status_is_a_key_driver_of_early.pdf

الاتاحة: https://mouseion.jax.org/stfb2024/212
https://doi.org/10.1002/alz.13842
https://mouseion.jax.org/context/stfb2024/article/1177/viewcontent/Alzheimer_s_Dementia___2024___Onos___Assessment_of_neurovascular_uncoupling_APOE_status_is_a_key_driver_of_early.pdf

المؤلفون: Sasner, Michael, Onos, Kristen D, Territo, Paul R, Sukoff Rizzo, Stacey J

المصدر: Faculty Research 2024

مصطلحات موضوعية: JMG, Alzheimer Disease, Humans, Translational Research, Biomedical, Animals, Disease Models, Animal, Biomarkers

وصف الملف: application/pdf

Relation: https://mouseion.jax.org/stfb2024/211; https://mouseion.jax.org/context/stfb2024/article/1178/viewcontent/Alzheimer_s_Dementia___2024___Sasner___Meeting_report_of_the_fifth_annual_workshop_on_Principles_and_Techniques_for.pdf

الاتاحة: https://mouseion.jax.org/stfb2024/211
https://doi.org/10.1002/alz.13742
https://mouseion.jax.org/context/stfb2024/article/1178/viewcontent/Alzheimer_s_Dementia___2024___Sasner___Meeting_report_of_the_fifth_annual_workshop_on_Principles_and_Techniques_for.pdf

المؤلفون: Onos, Kristen D., Lin, Peter B., Pandey, Ravi S., Persohn, Scott A., Burton, Charles P., Miner, Ethan W., Eldridge, Kierra, Nyandu Kanyind, Jonathan, Foley, Kate E., Carter, Gregory W., Howell, Gareth R., Territo, Paul R.

المساهمون: Neurology, School of Medicine

المصدر: PMC

مصطلحات موضوعية: APOE, Alzheimer's disease, Metabolism, Perfusion, Uncoupling

وصف الملف: application/pdf

Relation: Alzheimer’s & Dementia; Onos KD, Lin PB, Pandey RS, et al. Assessment of neurovascular uncoupling: APOE status is a key driver of early metabolic and vascular dysfunction. Alzheimers Dement. 2024;20(7):4951-4969. doi:10.1002/alz.13842; https://hdl.handle.net/1805/43346

الاتاحة: https://hdl.handle.net/1805/43346

المؤلفون: Telpoukhovskaia, Maria A., Murdy, Thomas J., Marola, Olivia J., Charland, Kevin, MacLean, Michael, Luquez, Tain, Lish, Alexandra M., Neuner, Sarah, Dunn, Amy, Onos, Kristen D., Wiley, Jesse, Archer, Derek, Huentelman, Matthew J., Arnold, Matthias, Menon, Vilas, Goate, Alison, Van Eldik, Linda J., Territo, Paul R., Howell, Gareth R., Carter, Gregory W., O’Connell, Kristen M. S., Kaczorowski, Catherine C., 2022 JAX CADR Workshop

المساهمون: Medicine, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Alzheimer's disease and related dementias (ADRD), ADRD therapeutics, Jackson Laboratory Center for Alzheimer's and Dementia Research (JAX CADR)

وصف الملف: application/pdf

Relation: Alzheimer’s & Dementia: Translational Research & Clinical Interventions; Telpoukhovskaia MA, Murdy TJ, Marola OJ, et al. New directions for Alzheimer's disease research from the Jackson Laboratory Center for Alzheimer's and Dementia Research 2022 workshop. Alzheimers Dement (N Y). 2024;10(1):e12458. Published 2024 Mar 10. doi:10.1002/trc2.12458; https://hdl.handle.net/1805/41938

الاتاحة: https://hdl.handle.net/1805/41938

المؤلفون: Burton, Charles P., Chumin, Evgeny J., Collins, Alyssa Y., Persohn, Scott A., Onos, Kristen D., Pandey, Ravi S., Quinney, Sara K., Territo, Paul R.

المساهمون: Radiology and Imaging Sciences, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Levetiracetam, Alzheimer’s disease, 5XFAD, Connectomics, Network neuroscience, PET imaging

وصف الملف: application/pdf

Relation: Frontiers in Neuroscience; Burton CP, Chumin EJ, Collins AY, et al. Levetiracetam modulates brain metabolic networks and transcriptomic signatures in the 5XFAD mouse model of Alzheimer's disease. Front Neurosci. 2024;17:1336026. Published 2024 Jan 24. doi:10.3389/fnins.2023.1336026; https://hdl.handle.net/1805/41515

الاتاحة: https://hdl.handle.net/1805/41515

المؤلفون: Burton, Charles P., Chumin, Evgeny J., Collins, Alyssa Y., Persohn, Scott A., Onos, Kristen D., Pandey, Ravi S., Quinney, Sara K., Territo, Paul R.

المساهمون: Radiology and Imaging Sciences, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Levetiracetam, Alzheimer’s disease, 5XFAD, Connectomics

وصف الملف: application/pdf

Relation: Burton CP, Chumin EJ, Collins AY, et al. Levetiracetam Modulates Brain Metabolic Networks and Transcriptomic Signatures in the 5XFAD Mouse Model of Alzheimer's disease. Preprint. bioRxiv. 2023;2023.11.10.566574. Published 2023 Dec 7. doi:10.1101/2023.11.10.566574; https://hdl.handle.net/1805/39880

الاتاحة: https://hdl.handle.net/1805/39880

المؤلفون: Heuer, Sarah E., Keezer, Kelly J., Hewes, Amanda A., Onos, Kristen D., Graham, Kourtney C., Howell, Gareth R., Bloss, Erik B.

المصدر: Alzheimer's & Dementia ; volume 20, issue 1, page 601-614 ; ISSN 1552-5260 1552-5279

الاتاحة: http://dx.doi.org/10.1002/alz.13440

المؤلفون: Quinney, Sara K., Murugesh, Kandasamy, Oblak, Adrian, Onos, Kristen D., Sasner, Mike, Greenwood, Anna K., Woo, Kara H., Rizzo, Stacey J. Sukoff, Territo, Paul R.

المصدر: Alzheimer's & Dementia ; volume 19, issue 11, page 5289-5295 ; ISSN 1552-5260 1552-5279

الاتاحة: http://dx.doi.org/10.1002/alz.13108

المؤلفون: Oblak, Adrian L., Cope, Zackary A., Quinney, Sara K., Pandey, Ravi S., Biesdorf, Carla, Masters, Andi R., Onos, Kristen D., Haynes, Leslie, Keezer, Kelly J., Meyer, Jill A., Peters, Jonathan S., Persohn, Scott A., Bedwell, Amanda A., Eldridge, Kierra, Speedy, Rachael, Little, Gabriela, Williams, Sean-Paul, Noarbe, Brenda, Obenaus, Andre, Sasner, Michael, Howell, Gareth R., Carter, Gregory W., Williams, Harriet, Lamb, Bruce T., Territo, Paul R., Sukoff Rizzo, Stacey J.

المساهمون: Radiology and Imaging Sciences, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Amyloid, BACE inhibitor, Mouse model, Preclinical testing

وصف الملف: application/pdf

Relation: Alzheimer's & Dementia: Translational Research & Clinical Interventions; Oblak AL, Cope ZA, Quinney SK, et al. Prophylactic evaluation of verubecestat on disease- and symptom-modifying effects in 5XFAD mice. Alzheimers Dement (N Y). 2022;8(1):e12317. Published 2022 Jul 14. doi:10.1002/trc2.12317; https://hdl.handle.net/1805/34422

الاتاحة: https://hdl.handle.net/1805/34422

المؤلفون: Onos, Kristen D., Quinney, Sara K., Jones, David R., Masters, Andrea R., Pandey, Ravi, Keezer, Kelly J., Biesdorf, Carla, Metzger, Ingrid F., Meyers, Jill A., Peters, Johnathon, Persohn, Scott C., McCarthy, Brian P., Bedwell, Amanda A., Figueiredo, Lucas L., Cope, Zackary A., Sasner, Michael, Howell, Gareth R., Williams, Harriet M., Oblak, Adrian L., Lamb, Bruce T., Carter, Gregory W., Rizzo, Stacey J. Sukoff, Territo, Paul R.

المصدر: Alzheimer's & Dementia: Translational Research & Clinical Interventions ; volume 8, issue 1 ; ISSN 2352-8737 2352-8737

الاتاحة: https://doi.org/10.1002/trc2.12329
https://onlinelibrary.wiley.com/doi/pdf/10.1002/trc2.12329
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/trc2.12329

المؤلفون: Onos, Kristen D, Keezer, Kelly J, Perkins, Bridget M, Perkins, Anne, Oblak, Adrian L, Howell, Gareth R

المصدر: Alzheimers Dement ; ISSN:1552-5279 ; Volume:20 Suppl 1

Relation: https://doi.org/10.1002/alz.092886; https://pubmed.ncbi.nlm.nih.gov/39750534

الاتاحة: https://doi.org/10.1002/alz.092886
https://pubmed.ncbi.nlm.nih.gov/39750534

المؤلفون: Marola, Olivia J, Onos, Kristen D, Diemler, Cory, Keezer, Kelly J, Sasner, Michael, Howell, Gareth R

المصدر: Alzheimers Dement ; ISSN:1552-5279 ; Volume:20 Suppl 1

Relation: https://doi.org/10.1002/alz.091446; https://pubmed.ncbi.nlm.nih.gov/39751602

الاتاحة: https://doi.org/10.1002/alz.091446
https://pubmed.ncbi.nlm.nih.gov/39751602

المؤلفون: Yang, Hongtian Stanley, Onos, Kristen D., Choi, Kwangbom, Keezer, Kelly J., Skelly, Daniel A., Carter, Gregory W., Howell, Gareth R.

المساهمون: National Institutes of Health, Alzheimer's Association

المصدر: Cell Reports ; volume 34, issue 6, page 108739 ; ISSN 2211-1247

الاتاحة: http://dx.doi.org/10.1016/j.celrep.2021.108739
https://api.elsevier.com/content/article/PII:S2211124721000528?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2211124721000528?httpAccept=text/plain

المؤلفون: Muraoka, Satoshi, Jedrychowski, Mark P., Iwahara, Naotoshi, Abdullah, Mohammad, Onos, Kristen D., Keezer, Kelly J., Hu, Jianqiao, Ikezu, Seiko, Howell, Gareth R., Gygi, Steven P., Ikezu, Tsuneya

المساهمون: Cure Alzheimer's Fund, National Institute on Aging, Alzheimer?s Association

المصدر: Journal of Proteome Research ; volume 20, issue 3, page 1733-1743 ; ISSN 1535-3893 1535-3907

الاتاحة: http://dx.doi.org/10.1021/acs.jproteome.0c00934
https://pubs.acs.org/doi/pdf/10.1021/acs.jproteome.0c00934

المؤلفون: Heuer, Sarah E., Keezer, Kelly J., Hewes, Amanda A., Onos, Kristen D., Graham, Kourtney C., Howell, Gareth R., Bloss, Erik B.

المصدر: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Jan2024, Vol. 20 Issue 1, p601-614, 14p

المؤلفون: Onos, Kristen D, Uyar, Asli, Keezer, Kelly J, Jackson, Harriet M, Preuss, Christoph, Acklin, Casey J, O'Rourke, Rita, Buchanan, Rebecca, Cossette, Travis L, Sukoff Rizzo, Stacey J, Soto Reyes, Ileana, Carter, Gregory W, Howell, Gareth R

المصدر: Faculty Scholarship for the College of Science & Mathematics

مصطلحات موضوعية: Genetics and Genomics, Medicine and Health Sciences

وصف الملف: application/pdf

Relation: https://rdw.rowan.edu/csm_facpub/146; https://rdw.rowan.edu/context/csm_facpub/article/1145/viewcontent/Soto_Reyes2019_PLoSGenetics_Enhancing.pdf

الاتاحة: https://rdw.rowan.edu/csm_facpub/146
https://doi.org/10.1371/journal.pgen.1008155
https://rdw.rowan.edu/context/csm_facpub/article/1145/viewcontent/Soto_Reyes2019_PLoSGenetics_Enhancing.pdf

المؤلفون: Howell, Gareth R, Marola, Olivia J, Maclean, Michael, Cossette, Travis L, Hewes, Amanda, Morgan, James, Singer, Cliff, Risacher, Shannon L., Onos, Kristen D, Reagan, Alaina M

المصدر: Alzheimer's & Dementia ; volume 19, issue S15 ; ISSN 1552-5260 1552-5279

الاتاحة: http://dx.doi.org/10.1002/alz.075348

المؤلفون: Heuer, Sarah E, Keezer, Kelly J, Hewes, Amanda, Onos, Kristen D, Bloss, Erik B, Howell, Gareth R

المصدر: Alzheimer's & Dementia ; volume 19, issue S12 ; ISSN 1552-5260 1552-5279

الاتاحة: http://dx.doi.org/10.1002/alz.074228

المؤلفون: Marola, Olivia J, Onos, Kristen D, Maclean, Michael, Keezer, Kelly J, Howell, Gareth R

المصدر: Alzheimer's & Dementia ; volume 19, issue S12 ; ISSN 1552-5260 1552-5279

الاتاحة: http://dx.doi.org/10.1002/alz.079766