المؤلفون: Durdağı, Serdar, Avşar, Timuçin, Orhan, Müge Didem, Serhatlı, Müge, Balcıoğlu, Bertan Koray, Öztürk, Hasan Ümit, Kayabölen, Alişan, Çetin, Yüksel, Aydınlık, Şeyma, Bağcı-Önder, Tuğba, Tekin, Şaban, Demirci, Hasan, Güzel, Mustafa, Akdemir, Atilla, Çalış, Şeyma, Oktay, Lalehan, Tolu, İlayda, Bütün, Yaşar Enes, Erdemoğlu, Ece, Olkan, Alpsu, Tokay, Nurettin, Işık, Şeyma, Özcan, Ayşenur, Acar, Elif, Büyükkılıç, Şehriban, Yumak, Yeşim

مصطلحات موضوعية: SARS-CoV-2, Vitro Studies, Montelukast, Silico Simulations

وصف الملف: application/pdf

Relation: Molecular Therapy; info:eu-repo/grantAgreement/TUBITAK/SOBAG/18AG003; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; Durdağı, S., Avşar, T., Orhan, M. D., Serhatlı, M., Balcıoğlu, B. K., Öztürk, H. Ü. . Yumak, Y. (2022). The neutralization effect of montelukast on SARS-CoV-2 is shown by multiscale in silico simulations and combined in vitro studies. Molecular Therapy, 30(2), 963-974. http://doi.org/10.1016/j.ymthe.2021.10.014; http://doi.org/10.1016/j.ymthe.2021.10.014; https://hdl.handle.net/20.500.12511/8994; 30; 963; 974; Q1; 000752448900006; 2-s2.0-85119042965

الاتاحة: https://hdl.handle.net/20.500.12511/8994
https://doi.org/10.1016/j.ymthe.2021.10.014

المؤلفون: Durdagi, Serdar, Avsar, Timucin, Orhan, Muge Didem, Serhatli, Muge, Balcioglu, Bertan Koray, Ozturk, Hasan Umit, Kayabolen, Alisan, Cetin, Yuksel, Aydinlik, Seyma, Bagci-Onder, Tugba, Tekin, Saban, Demirci, Hasan, Guzel, Mustafa, Akdemir, Atilla, Calis, Seyma, Oktay, Lalehan, Tolu, Ilayda, Butun, Yasar Enes, Erdemoglu, Ece, Olkan, Alpsu

المصدر: MOLECULAR THERAPY 30(2) 963-974

Relation: https://aperta.ulakbim.gov.tr/record/252661; oai:aperta.ulakbim.gov.tr:252661

الاتاحة: https://aperta.ulakbim.gov.tr/record/252661

المؤلفون: Durdagi, Serdar, Dağ, Çağdaş, Orhan, Muge D., Guven, Omur, Aksoydan, Busecan, Destan, Ebru, Sahin, Kader, Besler, Sabri O., Oktay, Lalehan, Shafiei, Alaleh, Tolu, Ilayda, Ayan, Esra, Dogan, Berna, Yuksel, Busra, Peksen, Ayse B., Gocenler, Oktay, Yucel, Ali D., Can, Ozgur, Ozabrahamyan, Serena, Olkan, Alpsu, Erdemoglu, Ece, Aksit, Fulya, Tanisali, Gokhan, Yigin, Merve, Yefanov, Oleksandr M., Barty, Anton, Tolstikova, Alexandra, Ketawala, Gihan K., Botha, Sabine, Dao, E. Han, Hayes, Brandon, Liang, Mengning, Seaberg, Matthew H., Hunter, Mark S., Avsar, Timucin, Batyuk, Alex, Mariani, Valerio, Su, Zhen, Poitevin, Frederic, Yoon, Chun Hong, Kupitz, Christopher, Sierra, Raymond G., Snell, Edward H., DeMirci, Hasan, Buyukdag, Cengizhan, Erol, Ismail, Ertem, Fatma Betul, Calis, Seyma, Yildirim, Gunseli

المصدر: Structure 29(12), 1382-1396.e6 (2021). doi:10.1016/j.str.2021.07.007

مصطلحات موضوعية: info:eu-repo/classification/ddc/540

جغرافية الموضوع: DE

Relation: info:eu-repo/semantics/altIdentifier/issn/1878-4186; info:eu-repo/semantics/altIdentifier/pmid/pmid:34403647; info:eu-repo/semantics/altIdentifier/wos/WOS:000728503500005; info:eu-repo/semantics/altIdentifier/issn/0969-2126; https://bib-pubdb1.desy.de/record/462438; https://bib-pubdb1.desy.de/search?p=id:%22PUBDB-2021-03415%22

الاتاحة: https://bib-pubdb1.desy.de/record/462438
https://bib-pubdb1.desy.de/search?p=id:%22PUBDB-2021-03415%22

المؤلفون: Oktay, Lalehan, Erdemoglu, Ece, Tolu, Ilayda, Yumak, Yesim, Ozcan, Aysenur, Acar, Elif, Buyukkilic, Sehriban, Olkan, Alpsu, Durdagi, Serdar

المصدر: TURKISH JOURNAL OF BIOLOGY 45(4) 459-+

Relation: https://aperta.ulakbim.gov.tr/record/233546; oai:aperta.ulakbim.gov.tr:233546

الاتاحة: https://aperta.ulakbim.gov.tr/record/233546

المؤلفون: Department of Molecular Biology and Genetics; Department of Chemical and Biological Engineering; Department of Materials Science and Engineering, Demirci, Hasan (ORCID 0000-0002-9135-5397 & YÖK ID 307350); Dağ, Çağdaş; Yığın, Merve; Büyükdağ, Cengizhan; Ertem, Fatma Betül; Yıldırım, Günseli; Destan, Ebru; Güven, Ömür; Ayan, Esra; Yüksel, Büşra; Pekşen, Ayşe Buket; Göçenler, Oktay; Yücel, Ali Doğa; Can, Özgür; Ozabrahamyan, Serena; Shafiei, Alaleh; Akşit, Fulya; Tanısalı, Gökhan; Besler, Sabri Özkan, Durdağı, Serdar; Doğan, Berna; Avşar, Timuçin; Erol, İsmail; Çalış, Şeyma; Orhan, Müge D.; Aksoydan, Busecan; Şahin, Kader; Oktay, Lalehan; Tolu, İlayda; Olkan, Alpsu; Erdemoğlu, Ece; Yefanov, Oleksandr M.; Dao, E. Han; Hayes, Brandon; Liang, Mengning; Seaberg, Matthew H.; Hunter, Mark S.; Batyuk, Alex; Mariani, Valerio; Su, Zhen; Poitevin, Frederic; Yoon, Chun Hong; Kupitz, Christopher; Sierra, Raymond G.; Snell, Edward H.

المصدر: Structure

مصطلحات الفهرس: Biochemistry and molecular biology; Biophysics; Cell biology, Ambient temperature; Drug repurposing; Main protease; SARS-CoV-2; SFX, Journal article, pdf

URL: http://libdigitalcollections.ku.edu.tr/cdm/ref/collection/IR/id/9794
http://libdigitalcollections.ku.edu.tr/utils/getthumbnail/collection/IR/id/9794
http://worldcat.org/oclc/1311243619/viewonline
Koç University Institutional Repository
References TÜBİTAK

المؤلفون: Kayabölen, Alişan; Önder, Tuğba Bağcı (ORCID 0000-0003-3646-2613 & YÖK ID 184359); Demirci, Hasan (ORCID 0000-0002-9135-5397 & YÖK ID 307350), Durdağı, Serdar; Avşar, Timuçin; Orhan, Müge Didem; Serhatlı, Müge; Balcıoğlu, Bertan Koray; Öztürk, Hasan Ümit; Çetin, Yüksel; Aydınlık, Şeyma; Tekin, Şaban; Güzel, Mustafa; Akdemir, Atilla; Çalış, Şeyma; Oktay, Lalehan; Tolu, İlayda; Bütün, Yaşar Enes; Erdemoğlu, Ece; Olkan, Alpsu; Tokay, Nurettin; Işık, Şeyma; Özcan, Ayşenur; Acar, Elif; Büyükkılıç, Şehriban; Yumak, Yeşim, Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM), School of Medicine; College of Sciences, Department of Molecular Biology and Genetics

المصدر: Molecular Therapy

مصطلحات الفهرس: Biotechnology and applied microbiology, COVID-19; Drug repurposing; MD simulations; Molecular docking; Montelukast; Pseudovirus Neutralization; Virus neutralization, Journal article, text/academic publication

URL: http://libdigitalcollections.ku.edu.tr/cdm/ref/collection/IR/id/10118
http://worldcat.org/oclc/1360590907/viewonline
Publisher version
Koç University Institutional Repository

المؤلفون: Demirci, Hasan (ORCID 0000-0002-9135-5397 & YÖK ID 307350); Dağ, Çağdaş; Yığın, Merve; Büyükdağ, Cengizhan; Ertem, Fatma Betül; Yıldırım, Günseli; Destan, Ebru; Güven, Ömür; Ayan, Esra; Yüksel, Büşra; Pekşen, Ayşe Buket; Göçenler, Oktay; Yücel, Ali Doğa; Can, Özgür; Ozabrahamyan, Serena; Shafiei, Alaleh; Akşit, Fulya; Tanısalı, Gökhan; Besler, Sabri Özkan, Durdağı, Serdar; Doğan, Berna; Avşar, Timuçin; Erol, İsmail; Çalış, Şeyma; Orhan, Müge D.; Aksoydan, Busecan; Şahin, Kader; Oktay, Lalehan; Tolu, İlayda; Olkan, Alpsu; Erdemoğlu, Ece; Yefanov, Oleksandr M.; Dao, E. Han; Hayes, Brandon; Liang, Mengning; Seaberg, Matthew H.; Hunter, Mark S.; Batyuk, Alex; Mariani, Valerio; Su, Zhen; Poitevin, Frederic; Yoon, Chun Hong; Kupitz, Christopher; Sierra, Raymond G.; Snell, Edward H., Koç Üniversitesi İş Bankası Enfeksiyon Hastalıkları Uygulama ve Araştırma Merkezi (EHAM) / Koç University İşbank Center for Infectious Diseases (KU-IS CID), College of Sciences; Graduate School of Sciences and Engineering; School of Nursing, Department of Molecular Biology and Genetics; Department of Chemical and Biological Engineering; Department of Materials Science and Engineering

المصدر: Structure

مصطلحات الفهرس: Biochemistry and molecular biology; Biophysics; Cell biology, Ambient temperature; Drug repurposing; Main protease; SARS-CoV-2; SFX, Journal article, pdf

URL: http://libdigitalcollections.ku.edu.tr/cdm/ref/collection/IR/id/9794
http://worldcat.org/oclc/1360588169/viewonline
Publisher version
Koç University Institutional Repository

المؤلفون: Durdagi, Serdar, Oktay, Lalehan, Erdemoglu, Ece, Tolu, Ilayda, Yumak, Yesim, Ozcan, Aysenur, Acar, Elif, Buyukkilic, Sehriban, Olkan, Alpsu

الاتاحة: http://dx.doi.org/10.33774/chemrxiv-2021-74mkk
https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/610aa85c30231a7ef90382c7/original/binary-qsar-guided-virtual-screening-of-fda-approved-drugs-and-compounds-in-clinical-investigation-against-sars-co-v-2-main-protease.pdf

المؤلفون: Durdagi, Serdar, Dağ, Çağdaş, Dogan, Berna, Yigin, Merve, Avsar, Timucin, Buyukdag, Cengizhan, Erol, Ismail, Ertem, Fatma Betul, Calis, Seyma, Yildirim, Gunseli, Orhan, Muge D., Guven, Omur, Aksoydan, Busecan, Destan, Ebru, Sahin, Kader, Besler, Sabri O., Oktay, Lalehan, Shafiei, Alaleh, Tolu, Ilayda, Ayan, Esra, Yuksel, Busra, Peksen, Ayse B., Gocenler, Oktay, Yucel, Ali D., Can, Ozgur, Ozabrahamyan, Serena, Olkan, Alpsu, Erdemoglu, Ece, Aksit, Fulya, Tanisali, Gokhan, Yefanov, Oleksandr M., Barty, Anton, Tolstikova, Alexandra, Ketawala, Gihan K., Botha, Sabine, Dao, E. Han, Hayes, Brandon, Liang, Mengning, Seaberg, Matthew H., Hunter, Mark S., Batyuk, Alex, Mariani, Valerio, Su, Zhen, Poitevin, Frederic, Yoon, Chun Hong, Kupitz, Christopher, Sierra, Raymond G., Snell, Edward H., DeMirci, Hasan

مصطلحات موضوعية: 59 BASIC BIOLOGICAL SCIENCES

وصف الملف: application/pdf

Relation: http://www.osti.gov/servlets/purl/1819309; https://www.osti.gov/biblio/1819309; https://doi.org/10.1016/j.str.2021.07.007

الاتاحة: http://www.osti.gov/servlets/purl/1819309
https://www.osti.gov/biblio/1819309
https://doi.org/10.1016/j.str.2021.07.007

المؤلفون: Durdagi, Serdar, Avsar, Timucin, Orhan, Muge Didem, Serhatli, Muge, Balcioglu, Bertan Koray, Ozturk, Hasan Umit, Kayabolen, Alisan, Cetin, Yuksel, Aydinlik, Seyma, Bagci-Onder, Tugba, Tekin, Saban, Demirci, Hasan, Guzel, Mustafa, Akdemir, Atilla, Calis, Seyma, Oktay, Lalehan, Tolu, Ilayda, Butun, Yasar Enes, Erdemoglu, Ece, Olkan, Alpsu, Tokay, Nurettin, Işık, Şeyma, Ozcan, Aysenur, Acar, Elif, Buyukkilic, Sehriban, Yumak, Yesim

المصدر: Molecular Therapy; 20210101, Issue: Preprints

المؤلفون: Ece Erdemoglu, Nurettin Tokay, Şaban Tekin, Lalehan Oktay, Elif Acar, Hasan DeMirci, Timucin Avsar, Alpsu Olkan, Yesim Yumak, Bertan Koray Balcioglu, Muge Didem Orhan, Seyma Calis, Hasan Umit Ozturk, Sehriban Buyukkilic, Yuksel Cetin, Yasar Enes Butun, Aysenur Ozcan, Atilla Akdemir, Muge Serhatli, Şeyma Işık, Tugba Bagci-Onder, Seyma Aydinlik, Mustafa Guzel, Serdar Durdagi, Alisan Kayabolen, Ilayda Tolu

المساهمون: Kayabölen, Alişan, Önder, Tuğba Bağcı (ORCID 0000-0003-3646-2613 & YÖK ID 184359), Demirci, Hasan (ORCID 0000-0002-9135-5397 & YÖK ID 307350), Durdağı, Serdar, Avşar, Timuçin, Orhan, Müge Didem, Serhatlı, Müge, Balcıoğlu, Bertan Koray, Öztürk, Hasan Ümit, Çetin, Yüksel, Aydınlık, Şeyma, Tekin, Şaban, Güzel, Mustafa, Akdemir, Atilla, Çalış, Şeyma, Oktay, Lalehan, Tolu, İlayda, Bütün, Yaşar Enes, Erdemoğlu, Ece, Olkan, Alpsu, Tokay, Nurettin, Işık, Şeyma, Özcan, Ayşenur, Acar, Elif, Büyükkılıç, Şehriban, Yumak, Yeşim, Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM), School of Medicine, College of Sciences, Department of Molecular Biology and Genetics, AKDEMİR, ATİLLA

المصدر: Molecular Therapy

مصطلحات موضوعية: Cyclopropanes, Models, Molecular, Vitro Studies, pseudovirus neutralization, Protein Conformation, medicine.medical_treatment, Pharmacology, Acetates, Neutralization, Drug Discovery, Chlorocebus aethiops, MD simulations, Leukotriene, drug repurposing, Molecular Structure, Chemistry, Biotechnology and applied microbiology, Serine Endopeptidases, Small molecule, Molecular Docking Simulation, montelukast, virus neutralization, Quinolines, Molecular Medicine, Original Article, Angiotensin-Converting Enzyme 2, medicine.drug, Cell Survival, COVID-19, Drug repurposing, Molecular docking, Montelukast, Pseudovirus Neutralization, Virus neutralization, Sulfides, Virus, Viral entry, Neutralization Tests, Genetics, medicine, Animals, Humans, Molecular Biology, Vero Cells, Protease, SARS-CoV-2, Silico Simulations, Drug Repositioning, molecular docking, Virus Internalization, In vitro, respiratory tract diseases, HEK293 Cells, A549 Cells

وصف الملف: pdf; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7b5bf178ea2423fe4889fd0a1d910a
https://pubmed.ncbi.nlm.nih.gov/34678509