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1Academic Journal
المؤلفون: Mathieu Cayla, Najma Rachidi, Olivier Leclercq, Dirk Schmidt-Arras, Heidi Rosenqvist, Martin Wiese, Gerald F Späth
المصدر: PLoS Pathogens, Vol 10, Iss 9, p e1004347 (2014)
مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5
وصف الملف: electronic resource
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2Academic Journal
المصدر: Frontiers in Microbiology, Vol 15 (2024)
مصطلحات موضوعية: epidemiology, resistance mechanisms, microbiota, whole genome sequencing, antibiotics, Microbiology, QR1-502
وصف الملف: electronic resource
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3Academic Journal
المؤلفون: Wai-Lok Yau, Thierry Blisnick, Jean-François Taly, Manuela Helmer-Citterich, Cordelia Schiene-Fischer, Olivier Leclercq, Jing Li, Dirk Schmidt-Arras, Miguel A Morales, Cedric Notredame, Daniel Romo, Philippe Bastin, Gerald F Späth
المصدر: PLoS Neglected Tropical Diseases, Vol 4, Iss 6, p e729 (2010)
مصطلحات موضوعية: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270
وصف الملف: electronic resource
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4Academic Journal
المؤلفون: Tihana Jovanic, Benjamin Roche, Géraldine Attal-Bonnefoy, Olivier Leclercq, François Rougeon
المصدر: PLoS ONE, Vol 3, Iss 1, p e1480 (2008)
وصف الملف: electronic resource
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5Academic Journal
المؤلفون: Sébastien Olivier Leclercq, Philippe Bochereau, Isabelle Foubert, Yannick Baumard, Angélique Travel, Benoît Doublet, Sylvie Baucheron
المصدر: Frontiers in Microbiology, Vol 15 (2024)
مصطلحات موضوعية: Escherichia coli, antimicrobial resistance, broiler production pyramid, longitudinal study, whole genome sequencing, Microbiology, QR1-502
وصف الملف: electronic resource
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6Academic Journal
المؤلفون: Gang Zhang, Qinna Cui, Jianjuan Li, Ruiliang Guo, Sébastien Olivier Leclercq, Lifeng Du, Na Tang, Yuqin Song, Chao Wang, Fangqing Zhao, Jie Feng
المصدر: Frontiers in Microbiology, Vol 13 (2022)
مصطلحات موضوعية: integrase, genomic island (GI), mobilization, ISCR elements, site-specific recombination, Microbiology, QR1-502
Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2022.905865/full; https://doaj.org/toc/1664-302X; https://doaj.org/article/c2f5c7674125478eaaa8b11cb13d80d8
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7
المؤلفون: Sébastien Olivier Leclercq, Philippe Bochereau, Isabelle Foubert, Yannick Baumard, Angélique Travel, Benoît Doublet, Sylvie Baucheron
مصطلحات موضوعية: Microbiology, Microbial Genetics, Microbial Ecology, Mycology, Escherichia coli, antimicrobial resistance, broiler production pyramid, longitudinal study, whole genome sequencing
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8Academic Journal
المؤلفون: Gang Zhang, Sébastien Olivier Leclercq, Jingjing Tian, Chao Wang, Koji Yahara, Guomin Ai, Shuangjiang Liu, Jie Feng
المصدر: PLoS Genetics, Vol 13, Iss 2, p e1006602 (2017)
Relation: http://europepmc.org/articles/PMC5313234?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404; https://doaj.org/article/bd6e44c85065423099b317982927bfd7
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9Image
المؤلفون: Gang Zhang, Qinna Cui, Jianjuan Li, Ruiliang Guo, Sébastien Olivier Leclercq, Lifeng Du, Na Tang, Yuqin Song, Chao Wang, Fangqing Zhao, Jie Feng
مصطلحات موضوعية: Microbiology, Microbial Genetics, Microbial Ecology, Mycology, integrase, genomic island (GI), mobilization, ISCR elements, site-specific recombination
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10
المؤلفون: Yaming Cui, Sébastien Olivier Leclercq
المصدر: The Anatomical Record. 300:238-250
مصطلحات موضوعية: 0106 biological sciences, 060101 anthropology, Histology, Ecology, Climatic variables, 06 humanities and the arts, Subtropics, respiratory system, Biology, 010603 evolutionary biology, 01 natural sciences, Variation (linguistics), Genetic distance, Temperate climate, 0601 history and archaeology, Anatomy, Adaptation, Ecology, Evolution, Behavior and Systematics, Biotechnology
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11
المؤلفون: Zhihai Sui, Chao Wang, Sébastien Olivier Leclercq, Jie Feng, Ye Deng, Hai Wu, Baoli Zhu
المصدر: Environmental Microbiology. 18:3494-3508
مصطلحات موضوعية: 2. Zero hunger, 0301 basic medicine, biology, medicine.drug_class, 030106 microbiology, Antibiotics, Pseudomonas, Acinetobacter, biology.organism_classification, Microbiology, Manure, Persistence (computer science), 03 medical and health sciences, Clostridium, medicine, Microcosm, Ecology, Evolution, Behavior and Systematics, Antibiotic resistance genes
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12
المؤلفون: Jie Feng, Gang Zhang, Chao Wang, Zhihai Sui, Meilin Zhao, Weiqi Chen, Sébastien Olivier Leclercq
المصدر: Environmental Microbiology. 17:1560-1573
مصطلحات موضوعية: Genetics, Comparative genomics, 0303 health sciences, Phylogenetic tree, biology, 030306 microbiology, fungi, Bacillus cereus, biology.organism_classification, Microbiology, 3. Good health, 03 medical and health sciences, Plasmid, Chromosomal region, Homologous recombination, Gene, Ecology, Evolution, Behavior and Systematics, Phosphotransferases, 030304 developmental biology
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13
المؤلفون: Eric Prina, Miguel A. Morales, Najma Rachidi, Gerald F. Späth, Albert Descoteaux, Olivier Leclercq, Mariko Dacher, Mathieu Cayla, Pascale Pescher
المصدر: Molecular Microbiology. 93:146-166
مصطلحات موضوعية: Genetics, Negative selection, Plasmid, Essential gene, Transgene, Druggability, Biology, Molecular Biology, Microbiology, Gene, Function (biology), Human morbidity
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14
المؤلفون: Jingjing Tian, Guomin Ai, Shuang-Jiang Liu, Sébastien Olivier Leclercq, Koji Yahara, Chao Wang, Jie Feng, Gang Zhang
المساهمون: Feng, Jie, Chinese Academy of Sciences (CAS), National Institute of Infectious Diseases [Tokyo], National Key Basic Research Development Plan of China (973 Program) (2015CB554202), National Natural Science Foundation of China (31500061)
المصدر: PLoS Genetics, Vol 13, Iss 2, p e1006602 (2017)
Plos Genetics 2 (13), 19 p. (2017)
PLoS Genetics
PLoS Genetics, Public Library of Science, 2017, 13 (2), 19 p. ⟨10.1371/journal.pgen.1006602⟩مصطلحات موضوعية: 0301 basic medicine, Acinetobacter baumannii, Cancer Research, Acinetobacter gyllenbergii, Spectinomycin, résistance aux antibiotiques, Pathology and Laboratory Medicine, Biochemistry, Plasmid, Antibiotics, Medicine and Health Sciences, Homologous Recombination, Genetics (clinical), Phylogeny, Data Management, Genetics, biology, Acinetobacter, Antimicrobials, Microbiology and Parasitology, Drugs, Phylogenetic Analysis, Drug Resistance, Microbial, Nucleotidyltransferases, Microbiologie et Parasitologie, Bacterial Pathogens, Nucleic acids, Phylogenetics, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Medical Microbiology, Host-Pathogen Interactions, Streptomycin, Electrophoresis, Polyacrylamide Gel, Pathogens, bactérie pathogène, medicine.drug, Research Article, Acinetobacter Infections, Computer and Information Sciences, Gene Transfer, Horizontal, lcsh:QH426-470, DNA recombination, 030106 microbiology, Microbial Sensitivity Tests, Research and Analysis Methods, Microbiology, 03 medical and health sciences, Antibiotic resistance, résistance aux antimicrobiens, Bacterial Proteins, Species Specificity, Microbial Control, medicine, Humans, Evolutionary Systematics, Molecular Biology Techniques, Microbial Pathogens, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Taxonomy, Pharmacology, Acinetobacter pittii, Evolutionary Biology, Molecular Biology Assays and Analysis Techniques, Bacteria, Organisms, Biology and Life Sciences, DNA, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, recombinaison, lcsh:Genetics, 030104 developmental biology, Antibiotic Resistance, Antimicrobial Resistance, transférase
وصف الملف: application/pdf
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15
المؤلفون: Antonio Palmeri, Erik Duelsner, Olivier Leclercq, Lisa von Kleist, Manuela Helmer-Citterich, Gerald F. Späth, Sabine Baumgart, Pier Federico Gherardini, Kathrin Bartho
المساهمون: Parasitologie moléculaire et Signalisation, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Caprotec Bioanalytics GmbH, Centre for Molecular Bioinformatics, Università degli Studi di Roma Tor Vergata [Roma], We thank Sophie Veillault for the editorial help. This work was supported by the 7th Framework Programme of the European Commission through a grant to the LEISHDRUG (223414) consortium, by the Agence Nationale de Recherche through a grant to the ANR-11-RPIB-0016 TRANSLEISH consortium, and the French Government's Investissements d'Avenir program: Laboratoire d'Excellence ‘Integrative Biology of Emerging Infectious Diseases’ (grant no. ANR-10-LABX-62-IBEID)., ANR-11-RPIB-0016,TRANSLEISH,Découverte de nouvelles protéines kinases chez Leishmania donovani à partir des inhibiteurs tête de série issus d'un criblage phénotypique(2011), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), European Project: 223414,EC:FP7:HEALTH,FP7-HEALTH-2007-B,LEISHDRUG(2008), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Journal of Proteomics; Vol 86
Journal of Proteomics
Journal of Proteomics, Elsevier, 2013, 86, pp.97-104. ⟨10.1016/j.jprot.2013.05.002⟩
Journal of Proteomics, 2013, 86, pp.97-104. ⟨10.1016/j.jprot.2013.05.002⟩مصطلحات موضوعية: Proteomics, MESH: Gene Ontology, Biophysics, Leishmania donovani, Protozoan Proteins, MESH: Carrier Proteins, Biochemistry, DNA-binding protein, Mass Spectrometry, Protein kinase, 03 medical and health sciences, Adenosine Triphosphate, Tandem Mass Spectrometry, MESH: Adenosine Triphosphate, medicine, Staurosporine, Kinase activity, Protein kinase A, Amastigote, MESH: Protein Kinases, MESH: Protozoan Proteins, 030304 developmental biology, 0303 health sciences, MESH: Leishmania donovani, biology, Kinase, Settore BIO/11, MESH: Proteomics, 030302 biochemistry & molecular biology, MESH: Tandem Mass Spectrometry, biology.organism_classification, Capture Compound, Gene Ontology, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, MESH: Staurosporine, Sequence motif, Carrier Proteins, Protein Kinases, MESH: Chromatography, Liquid, medicine.drug, Chromatography, Liquid
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16
المؤلفون: Laurent Meijer, Gerald F. Späth, Alexios-Leandros Skaltsounis, Nicolas Gaboriaud-Kolar, Nathalie Aulner, Olivier Leclercq, Konstantina Vougogiannopoulou, Audrey Defontaine, Nassima Oumata, Hervé Galons, Emilie Durieu, Eric Prina, Najma Rachidi, Sandrine Ruchaud, Joo Hwan No
المساهمون: Phophorylation de protéines et Pathologies Humaines (P3H), Station biologique de Roscoff [Roscoff] (SBR), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Immunophysiologie et Parasitisme Intracellulaire, Institut Pasteur [Paris] (IP), Parasitologie moléculaire et Signalisation / Molecular Parasitology and Signaling, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), ManRos Therapeutics, Department of Pharmacognosy and Chemistry of Natural Products, National and Kapodistrian University of Athens (NKUA), Imagopole (CITECH), Institut Pasteur Korea - Institut Pasteur de Corée, Réseau International des Instituts Pasteur (RIIP), Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques (LCBPT - UMR 8601), Université Paris Descartes - Paris 5 (UPD5)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), This study was supported by the 7th Framework Program of the European Commission through grants to the LEISHDRUG project (223414), by ANR-11-RPIB-0016 TRANSLEISH, and by the French Government's Investissements d'Avenir Program Laboratoire d'Excellence Integrative Biology of Emerging Infectious Diseases (grant ANR-10-LABX-62-IBEID). The Imagopole-CiTech is part of the FranceBioImaging infrastructure supported by the French National Research Agency (ANR-10-INSB-04-01, Investments for the Future) and is supported by the Conseil de la Region Ile-de-France (program Sesame 2007, project Imagopole, S. Shorte) and the Fondation Française pour la Recherche Médicale (Programme Grands Equipements [N.A.]), ANR-11-RPIB-0016,TRANSLEISH,Découverte de nouvelles protéines kinases chez Leishmania donovani à partir des inhibiteurs tête de série issus d'un criblage phénotypique(2011), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), ANR-10-INBS-0004,France-BioImaging,Développment d'une infrastructure française distribuée coordonnée(2010), European Project: 223414,EC:FP7:HEALTH,FP7-HEALTH-2007-B,LEISHDRUG(2008), Institut Pasteur [Paris], Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur [Paris], Parasitologie moléculaire et Signalisation, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), National and Kapodistrian University of Athens = University of Athens (NKUA | UoA), Institut Pasteur de Corée, Université Paris Descartes - Paris 5 (UPD5)-Centre National de la Recherche Scientifique (CNRS), ANR-11-RPIB-0016,TRANSLEISH,Découverte de nouvelles protéines kinases chez Leishmania donovani à partir des inhibiteurs tête de série issus d’un criblage phénotypique(2011), ANR-10-LABX-0062/10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), ANR-10-INBS-04-01/10-INBS-0004,France-BioImaging,Développment d'une infrastructure française distribuée coordonnée(2010), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Station biologique de Roscoff [Roscoff] (SBR), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, 2016, ⟨10.1128/AAC.00021-16⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2016, ⟨10.1128/AAC.00021-16⟩مصطلحات موضوعية: 0301 basic medicine, 030106 microbiology, Antiprotozoal Agents, Biology, Cell Line, 03 medical and health sciences, Casein Kinase I, Drug Discovery, Animals, Humans, Protein Isoforms, [CHIM]Chemical Sciences, Pharmacology (medical), Amastigote, Leishmania, Pharmacology, Kinase, Drug discovery, Intracellular parasite, Macrophages, Biological activity, biology.organism_classification, 3. Good health, 030104 developmental biology, Infectious Diseases, Biochemistry, Casein kinase 1
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17
المؤلفون: Jie Feng, Sébastien Olivier Leclercq, Chao Wang, Xiaochen Du, Yaxin Zhu, Zhi-Pei Liu, Hai Wu
المساهمون: Chinese Academy of Sciences (CAS), College of Life Sciences, Hebei University, National Science and Technology Support Program (2013BAD21B02-04), National Natural Science Foundation of China (NSFC) (31450110073), Chinese Academy of Sciences (CAS) (2013Y2SB0004)
المصدر: Applied and Environmental Microbiology
Applied and Environmental Microbiology, American Society for Microbiology, 2016, 82 (21), pp.6454-6462. ⟨10.1128/AEM.01754-16⟩مصطلحات موضوعية: 0301 basic medicine, Transposable element, China, Livestock, Tetracycline, Swine, 030106 microbiology, Sus scrofa, Biology, Applied Microbiology and Biotechnology, 03 medical and health sciences, Antibiotic resistance, medicine, Animals, Gene, Soil Microbiology, Gene Library, 2. Zero hunger, Genetics, Ecology, Bacteria, Public and Environmental Health Microbiology, Tetracycline Resistance, Computational Biology, Genetic Variation, High-Throughput Nucleotide Sequencing, Manure, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Metagenomics, Genes, Bacterial, DNA Transposable Elements, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Mobilome, Mobile genetic elements, Food Science, Biotechnology, medicine.drug
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18
المؤلفون: Sebastien Olivier, Leclercq, Chao, Wang, Zhihai, Sui, Hai, Wu, Baoli, Zhu, Ye, Deng, Jie, Feng
المساهمون: Chinese Academy of Sciences (CAS), College of Life Sciences, Hebei University, National Key Basic Research Development Plan of China (973 Program) (2015CB554202), National Natural Science Foundation of China (31450110073), Chinese Academy of Sciences (2013Y2SB0004)
المصدر: Environmental Microbiology
Environmental Microbiology, Society for Applied Microbiology and Wiley-Blackwell, 2016, 18 (10), pp.3494-3508. ⟨10.1111/1462-2920.13337⟩مصطلحات موضوعية: Clostridium, Manure, Soil, Acinetobacter, Pseudomonas, [SDV]Life Sciences [q-bio], Drug Resistance, Bacterial, Animals, Agriculture, Environment, Soil Microbiology, Anti-Bacterial Agents
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19
المؤلفون: Gerald F. Späth, Martin Wiese, Mathieu Cayla, Olivier Leclercq, Najma Rachidi, Heidi Rosenqvist, Dirk Schmidt-Arras
المساهمون: Parasitologie moléculaire et Signalisation, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Protein Research Group, University of Southern Denmark (SDU), Strathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde [Glasgow], This work was supported by 7th Framework Programme of the European Commission through a grant to the LEISHDRUG Project (223414), the French Government’s Investissements d’Avenir program: Laboratoire d’Excellence ‘‘Integrative Biology of Emerging Infectious Diseases’’ (grant no. ANR-10-LABX-62-IBEID), and ANR-11-RPIB-0016 TRANSLEISH. MC was supported by a grant from Re ́gion Ile de France. MW and HR were supported by the Deutsche Forschungsgemeinschaft DFG (WI 2044/5-1). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript., ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), ANR-11-RPIB-0016,TRANSLEISH,Découverte de nouvelles protéines kinases chez Leishmania donovani à partir des inhibiteurs tête de série issus d'un criblage phénotypique(2011), European Project: 223414,EC:FP7:HEALTH,FP7-HEALTH-2007-B,LEISHDRUG(2008), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Strathclyde Institute for Pharmacy and Biomedical Sciences (SIPBS)
المصدر: PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2014, 10 (9), pp.e1004347. ⟨10.1371/journal.ppat.1004347⟩
Cayla, M, Rachidi, N, Leclercq, O, Schmidt-Arras, D, Rosenqvist, H, Wiese, M & Spath, G F 2014, ' Transgenic Analysis of the Leishmania MAP Kinase MPK10 Reveals an Auto-inhibitory Mechanism Crucial for Stage-Regulated Activity and Parasite Viability ', P L o S Pathogens, bind 10, nr. 9, s. 18 . https://doi.org/10.1371/journal.ppat.1004347
PLoS Pathogens, 2014, 10 (9), pp.e1004347. ⟨10.1371/journal.ppat.1004347⟩
Cayla, M, Rachidi, N, Leclercq, O, Schmidt-Arras, D, Rosenqvist, H, Wiese, M & Späth, G F 2014, ' Transgenic analysis of the Leishmania MAP kinase MPK10 reveals an auto-inhibitory mechanism crucial for stage-regulated activity and parasite viability ', PLoS Pathogens, vol. 10, no. 9 . https://doi.org/10.1371/journal.ppat.1004347
PLoS Pathogens, Vol 10, Iss 9, p e1004347 (2014)مصطلحات موضوعية: Cell signaling, auto-inhibition, Cellular differentiation, Signal transduction, Protozoology, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Phosphorylation, lcsh:QH301-705.5, Cells, Cultured, Feedback, Physiological, 0303 health sciences, Kinase, 030302 biochemistry & molecular biology, Phosphoproteomics, Microbial Genetics, Signaling cascades, Cell biology, Biochemistry, Mitogen-activated protein kinase, Leishmaniasis, Visceral, Mitogen-Activated Protein Kinases, Research Article, lcsh:Immunologic diseases. Allergy, MAPK signaling cascades, Cell Survival, Immunology, Blotting, Western, Green Fluorescent Proteins, Molecular Sequence Data, MAP kinase MPK10, Biology, Microbiology, ACTIVATED PROTEIN-KINASE DUAL PHOSPHORYLATION FLAGELLAR-LENGTH IN-VITRO TRYPANOSOMA-BRUCEI AXENIC AMASTIGOTES CRYSTAL-STRUCTURE MITOGEN DONOVANI MEXICANA, RS, Molecular Genetics, 03 medical and health sciences, structure-function analysis, Virology, Genetics, Humans, [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Amino Acid Sequence, Kinase activity, Amastigote, Protein kinase A, Molecular Biology, 030304 developmental biology, Biology and life sciences, Sequence Homology, Amino Acid, Kinetoplastids, transgenic expression, lcsh:Biology (General), Mutagenesis, biology.protein, Parasitology, lcsh:RC581-607, Leishmania donovani
وصف الملف: application/pdf
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المؤلفون: Mariko, Dacher, Miguel A, Morales, Pascale, Pescher, Olivier, Leclercq, Najma, Rachidi, Eric, Prina, Mathieu, Cayla, Albert, Descoteaux, Gerald F, Späth
المصدر: Molecular microbiology. 93(1)
مصطلحات موضوعية: Mice, Inbred BALB C, Genes, Essential, Cell Death, Genes, Viral, Macrophages, Protozoan Proteins, Leishmaniasis, Cutaneous, Thymidine Kinase, Gene Knockout Techniques, Mice, Mutation, Animals, Simplexvirus, Female, Mitogen-Activated Protein Kinases, Ganciclovir, Leishmania major, Plasmids