المؤلفون: Xiang Wang, Vitaliy V Bondar, Oliver B Davis, Michael T Maloney, Maayan Agam, Marcus Y Chin, Audrey Cheuk-Nga Ho, Rajarshi Ghosh, Dara E Leto, David Joy, Meredith EK Calvert, Joseph W Lewcock, Gilbert Di Paolo, Robert G Thorne, Zachary K Sweeney, Anastasia G Henry

المصدر: eLife, Vol 12 (2023)

مصطلحات موضوعية: LRRK2, lysosomal damage, Rab12, Parkinson's disease, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/87255; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/1459c4b9a28a4c35be189566695ad7a3

المؤلفون: Vitaliy V. Bondar, Xiang Wang, Oliver B. Davis, Michael T. Maloney, Maayan Agam, Marcus Y. Chin, Audrey Cheuk-Nga Ho, David Joy, Joseph W. Lewcock, Gilbert Di Paolo, Robert G. Thorne, Zachary K. Sweeney, Anastasia G. Henry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::41e3b9441d471cebda4108d94643d132
https://doi.org/10.1101/2023.02.21.529466

المؤلفون: Michael T. Maloney, Xiang Wang, Rajarshi Ghosh, Shan V. Andrews, Romeo Maciuca, Shababa T. Masoud, Richard M. Caprioli, John Chen, Chi-Lu Chiu, Sonnet S. Davis, Audrey Cheuk-Nga Ho, Hoang N. Nguyen, Nicholas E. Propson, Michelle L. Reyzer, Oliver B. Davis, Matthew C. Deen, Sha Zhu, Gilbert Di Paolo, David J. Vocadlo, Anthony A. Estrada, Javier de Vicente, Joseph W. Lewcock, Annie Arguello, Jung H. Suh, Sarah Huntwork-Rodriguez, Anastasia G. Henry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dc13473cd36348881c86cb13ff023e4d
https://doi.org/10.1101/2022.12.19.521070

المؤلفون: Hijai R. Shin, Y. Rose Citron, Lei Wang, Laura Tribouillard, Claire S. Goul, Robin Stipp, Yusuke Sugasawa, Aakriti Jain, Nolwenn Samson, Chun-Yan Lim, Oliver B. Davis, David Castaneda-Carpio, Mingxing Qian, Daniel K. Nomura, Rushika M. Perera, Eunyong Park, Douglas F. Covey, Mathieu Laplante, Alex S. Evers, Roberto Zoncu

المصدر: Science (New York, N.Y.), vol 377, iss 6612
Science

مصطلحات موضوعية: Multidisciplinary, Proteome, General Science & Technology, 1.1 Normal biological development and functioning, GTPase-Activating Proteins, Mechanistic Target of Rapamycin Complex 1, Article, Receptors, G-Protein-Coupled, G-Protein-Coupled, Cholesterol, Underpinning research, Receptors, Humans, Lysosomes, Monomeric GTP-Binding Proteins

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5679d35b76dd78baa098dc74865d1898
https://escholarship.org/uc/item/8g07j454

المؤلفون: Daniel K. Nomura, Roberto Zoncu, Hijai R. Shin, Xuntian Jiang, Justin Zhang, Charles A. Berdan, Daniel S. Ory, Oliver B. Davis, Chun Yan Lim, Jessica L. Counihan

المصدر: Nature cell biology

مصطلحات موضوعية: Receptors, Steroid, Vesicular Transport Proteins, GTPase, Mechanistic Target of Rapamycin Complex 1, Endoplasmic Reticulum, Article, Mice, 03 medical and health sciences, 0302 clinical medicine, Niemann-Pick C1 Protein, Lysosome, medicine, Animals, Humans, OSBP, 030304 developmental biology, Niemann-Pick Diseases, 0303 health sciences, Membrane Glycoproteins, Chemistry, Endoplasmic reticulum, Intracellular Signaling Peptides and Proteins, Cell Biology, VAPB, Cell biology, Cholesterol, HEK293 Cells, medicine.anatomical_structure, 030220 oncology & carcinogenesis, lipids (amino acids, peptides, and proteins), biological phenomena, cell phenomena, and immunity, NPC1, Signal transduction, Carrier Proteins, Lysosomes, Oxysterol-binding protein, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6838c4939e12f458f5a6376ecf5724b4
https://doi.org/10.1038/s41556-019-0391-5

المؤلفون: Matthew Kukurugya, Emma Y. Wu, Hijai R. Shin, Oliver B. Davis, M. Paulina Ordonez, Chun-Yan Lim, Claire F. Maher, Roberto Zoncu, Rushika M. Perera

مصطلحات موضوعية: Chemistry, Kinase, Neurodegeneration, Organelle, medicine, Cellular homeostasis, mTORC1, biological phenomena, cell phenomena, and immunity, NPC1, medicine.disease, Cholesterol storage, Homeostasis, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ce7b50644313b1e5d6e5f4ee901f8995
https://doi.org/10.1101/2020.08.02.233254

المؤلفون: M. Paulina Ordonez, Oliver B. Davis, Roberto Zoncu, Claire F. Maher, Hijai R. Shin, Chun-Yan Lim, Emma Y. Wu, Matthew Kukurugya, Rushika M. Perera

المصدر: Developmental cell. 56(3)

مصطلحات موضوعية: Adult, Induced Pluripotent Stem Cells, Cellular homeostasis, mTORC1, Mitochondrion, Biology, Mechanistic Target of Rapamycin Complex 1, Models, Biological, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Mice, 0302 clinical medicine, Niemann-Pick C1 Protein, Lysosome, Mitophagy, Organelle, medicine, Animals, Homeostasis, Humans, Molecular Biology, Cells, Cultured, 030304 developmental biology, Neurons, Organelles, 0303 health sciences, Intracellular Signaling Peptides and Proteins, Niemann-Pick Disease, Type C, Cell Biology, Intracellular Membranes, Cell biology, Mitochondria, medicine.anatomical_structure, Cholesterol, HEK293 Cells, Proteolysis, biological phenomena, cell phenomena, and immunity, NPC1, Cholesterol storage, Lysosomes, 030217 neurology & neurosurgery, Developmental Biology, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::050e12741d8b07c155dbe5f026bf8117
https://pubmed.ncbi.nlm.nih.gov/33561418

المؤلفون: Oliver B. Davis, Edoardo Nusco, Roberto Zoncu, Chiara Di Malta, Angela Zampelli, Margret H. Ogmundsdottir, Carmine Settembre, Rossella De Cegli, Andrea N. Eastes, Nunzia Pastore, Alessandro Guida, Diletta Siciliano, Andrea Ballabio, Luca Giovanni Di Giovannantonio, Pier Giuseppe Pelicci, Simona Punzi, Rushika M. Perera, Alessia Calcagni, Luisa Lanfrancone, Jlenia Monfregola, Nick Platt

المساهمون: DI MALTA, Chiara, Siciliano, Diletta, Calcagni, Alessia, Monfregola, Jlenia, Punzi, Simona, Pastore, Nunzia, Eastes, Andrea N, Davis, Oliver, De Cegli, Rossella, Zampelli, Angela, Di Giovannantonio, Luca G, Nusco, Edoardo, Platt, Nick, Guida, Alessandro, Ogmundsdottir, Margret Helga, Lanfrancone, Luisa, Perera, Rushika M, Zoncu, Roberto, Pelicci, Pier Giuseppe, Settembre, Carmine, Ballabio, Andrea

المصدر: Science (N. Y., N.Y.) 356 (2017): 1188–1192. doi:10.1126/science.aag2553
info:cnr-pdr/source/autori:Di Malta, Chiara; Siciliano, Diletta; Calcagni, Alessia; Monfregola, Jlenia; Punzi, Simona; Pastore, Nunzia; Eastes, Andrea N.; Davis, Oliver; De Cegli, Rossella; Zampelli, Angela; Di Giovannantonio, Luca G.; Nusco, Edoardo; Platt, Nick; Guida, Alessandro; Ogmundsdottir, Margret Helga; Lanfrancone, Luisa; Perera, Rushika M.; Zoncu, Roberto; Pelicci, Pier Giuseppe; Settembre, Carmine; Ballabio, Andrea/titolo:Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth/doi:10.1126%2Fscience.aag2553/rivista:Science (N. Y., N.Y.)/anno:2017/pagina_da:1188/pagina_a:1192/intervallo_pagine:1188–1192/volume:356
Science (New York, N.Y.), vol 356, iss 6343
Science
Cell Stress

مصطلحات موضوعية: Male, 0301 basic medicine, Tfeb, GTPase, mTORC1, Inbred C57BL, Mice, chemistry.chemical_compound, Transcription (biology), Neoplasms, 2.1 Biological and endogenous factors, Aetiology, Cells, Cultured, Cancer, Feedback, Physiological, 2. Zero hunger, News and Thoughts, Cultured, Tumor, Multidisciplinary, Hep G2 Cells, Cell biology, Gene Expression Regulation, Neoplastic, Mtorc1, medicine.anatomical_structure, Liver, Biochemistry, Transcription, Signal Transduction, autophagy, Cellular adaptation, General Science & Technology, Cells, Physiological, 1.1 Normal biological development and functioning, Guanosine, Mechanistic Target of Rapamycin Complex 1, Biology, Ragd, cancer growth, Cell Line, Feedback, 03 medical and health sciences, Underpinning research, Cell Line, Tumor, Lysosome, Genetics, medicine, Animals, Humans, Caloric Restriction, Cell Proliferation, Nutrition, Neoplastic, Mice, Inbred C57BL, Metabolism, HEK293 Cells, 030104 developmental biology, Gene Expression Regulation, chemistry, Hela Cells, Cancer cell, Digestive Diseases, Biogenesis, HeLa Cells

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6db408543e4c6719e8d0eebdd2ae18f2
https://doi.org/10.1126/science.aag2553

المؤلفون: Xuntian Jiang, Roberto Zoncu, Daniel K. Nomura, Ofer Moldavski, Laurel Mydock-McGrane, Daniel S. Ory, McKenna Feltes, Oliver B. Davis, Robert J. van Eijkeren, Rushika M. Perera, Brian M. Castellano, Sharon M. Louie, Douglas F. Covey, Ashley M. Thelen, Reini E. N. van der Welle

المصدر: Science (New York, N.Y.), vol 355, iss 6331

مصطلحات موضوعية: 0301 basic medicine, Amino Acid Transport Systems, HDL, General Science & Technology, 1.1 Normal biological development and functioning, Amino Acid Motifs, CHO Cells, mTORC1, Mechanistic Target of Rapamycin Complex 1, Biology, Article, Mice, 03 medical and health sciences, chemistry.chemical_compound, Cricetulus, Underpinning research, Lysosome, medicine, Animals, Humans, Protein kinase A, Multidisciplinary, Cell growth, Cholesterol, TOR Serine-Threonine Kinases, Cholesterol, HDL, Nuclear Proteins, Biological Transport, Fibroblasts, Sterol transport, Transmembrane protein, Enzyme Activation, HEK293 Cells, 030104 developmental biology, medicine.anatomical_structure, chemistry, Biochemistry, Multiprotein Complexes, Mutation, lipids (amino acids, peptides, and proteins), biological phenomena, cell phenomena, and immunity, NPC1, Lysosomes, Carrier Proteins, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a65da3c4ebec37664cd3e27fa1635d
https://doi.org/10.1126/science.aag1417

المؤلفون: Mary Carrington, Bruce D. Walker, Damien Z. Soghoian, Daniel Karel, Carl M. Kadie, Oliver B. Davis, Ariel Goldenthal, Alicja Piechocka, Jian Peng, David Heckerman, Jonathan M. Carlson, Florencia Pereyra, Tien-Ho Lin, Charles E. DeZiel

المصدر: Journal of Virology. 88:12937-12948

مصطلحات موضوعية: Adult, Male, Enzyme-Linked Immunospot Assay, In silico, Immunology, HIV Infections, Human leukocyte antigen, CD8-Positive T-Lymphocytes, Biology, Microbiology, Epitope, Cohort Studies, Epitopes, Interferon-gamma, Immune system, Virology, Humans, Cytotoxic T cell, HIV vaccine, ELISPOT, Histocompatibility Antigens Class I, Computational Biology, Middle Aged, Insect Science, HIV-1, Pathogenesis and Immunity, Female, CD8

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bba36e37bcc22ae49246fda40f2a099
https://doi.org/10.1128/jvi.01004-14

المؤلفون: Anthony C. Bishop, Oliver B. Davis

المصدر: Bioconjugate Chemistry. 23:272-278

مصطلحات موضوعية: Models, Molecular, Protein domain, Biomedical Engineering, Pharmaceutical Science, Bioengineering, Protein tyrosine phosphatase, Protein Engineering, medicine.disease_cause, Article, Arsenicals, Fluorescence, Structure-Activity Relationship, Escherichia coli, medicine, Amino Acid Sequence, Peptide sequence, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Pharmacology, Mutation, Molecular Structure, Chemistry, Organic Chemistry, Protein engineering, Biochemistry, Molecular Probes, Signal transduction, Molecular probe, hormones, hormone substitutes, and hormone antagonists, Biotechnology, Cysteine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e915bf2ed54b646672527bec270e9320
https://doi.org/10.1021/bc200562y