المؤلفون: Christer S. Ejsing, Sandra F Gallego, Anthony H. Futerman, Richard R. Sprenger, Ole N. Jensen, Nanna Albæk, Steffen Schmidt, Marie W. Lindholm, Charlotte Øverup, Yael Pewzner-Jung, Sergey Kovalchuk, Iris D. Zelnik

المصدر: Mol Ther
Schmidt, S, Gallego, S F, Zelnik, I D, Kovalchuk, S, Albæk, N, Sprenger, R R, Øverup, C, Pewzner-Jung, Y, Futerman, A H, Lindholm, M W, Jensen, O N & Ejsing, C S 2022, ' Silencing of ceramide synthase 2 in hepatocytes modulates plasma ceramide biomarkers predictive of cardiovascular death ', Molecular Therapy, vol. 30, no. 4, pp. 1661-1674 . https://doi.org/10.1016/j.ymthe.2021.08.021

مصطلحات موضوعية: Oligonucleotides, Antisense/genetics, Research & Experimental Medicine, Proteomics, DISEASE, PCSK9, Plasma, chemistry.chemical_compound, 0302 clinical medicine, cardiovascular disease, Drug Discovery, Medicine, Genetics & Heredity, chemistry.chemical_classification, 0303 health sciences, CHOLESTEROL, Ceramide synthase 2, 3. Good health, Medicine, Research & Experimental, Cardiovascular Diseases, Molecular Medicine, ceramide synthase 2, Oxidoreductases, Life Sciences & Biomedicine, Ceramide, government.form_of_government, INHIBITION, liver, Ceramides, ANTISENSE OLIGONUCLEOTIDES, DELIVERY, 03 medical and health sciences, proteomics, Oxidoreductases/antagonists & inhibitors, Lipidomics, Cardiovascular Diseases/genetics, Genetics, Mus musculus, Humans, Gene silencing, Gene Silencing, Molecular Biology, 030304 developmental biology, Pharmacology, Antisense therapy, Science & Technology, sphingolipids, business.industry, ceramide biomarkers, antisense therapy, Oligonucleotides, Antisense, Sphingolipid, REDUCTION, MICE, Enzyme, Biotechnology & Applied Microbiology, chemistry, Hepatocytes, Commentary, Cancer research, government, RNA, lipidomics, LIPIDOME, business, Biomarkers, 030217 neurology & neurosurgery

وصف الملف: application/pdf; Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b0e637383248c3671fcfcbf8c482c6
https://doi.org/10.1016/j.ymthe.2021.08.021

المؤلفون: Anja Holm, Stine N. Hansen, Henrik Klitgaard, Sakari Kauppinen

المصدر: Holm, A, Hansen, S N, Klitgaard, H & Kauppinen, S 2022, ' Clinical advances of RNA therapeutics for treatment of neurological and neuromuscular diseases ', RNA Biology, vol. 19, no. 1, pp. 594-608 . https://doi.org/10.1080/15476286.2022.2066334

مصطلحات موضوعية: RNA, Small Interfering/genetics, Amyloid Neuropathies, Familial, Oligonucleotides, Antisense/genetics, Amyotrophic Lateral Sclerosis, Amyotrophic Lateral Sclerosis/genetics, Cell Biology, Neuromuscular Diseases, Neuromuscular Diseases/drug therapy, Oligonucleotides, Antisense, United States, Quality of Life, Animals, RNA, Messenger, RNA, Small Interfering, Molecular Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea210bd5f94a483d8b7e4fb573343f21
https://pubmed.ncbi.nlm.nih.gov/35482908

المؤلفون: Imad Ghazi, Isabelle Perrault, Nicolas Goudin, Jean-Michel Rozet, Josseline Kaplan, Sabine Defoort-Dhellemmes, Iris Barny, Christel Michel, Xavier Gérard

المصدر: Genes, Vol 10, Iss 5, p 368 (2019)
Genes, vol. 10, no. 5

مصطلحات موضوعية: 0301 basic medicine, lcsh:QH426-470, 030105 genetics & heredity, Biology, spontaneous nonsense correction, medicine.disease_cause, 03 medical and health sciences, chemistry.chemical_compound, Exon, Genetics, medicine, Leber congenital amaurosis and allied retinal ciliopathies, Genetics (clinical), Flanders founder c.4723A >, Mutation, Cilium, Retinal, medicine.disease, Molecular biology, Exon skipping, Cilia elongation, Ciliopathy, Antigens, Neoplasm/genetics, Antigens, Neoplasm/metabolism, Cell Cycle Proteins/genetics, Cell Cycle Proteins/metabolism, Codon, Nonsense, Cytoskeletal Proteins/genetics, Cytoskeletal Proteins/metabolism, Exons/genetics, Eye Abnormalities/genetics, Eye Diseases, Hereditary/genetics, Humans, Male, Neoplasm Proteins/genetics, Oligonucleotides, Antisense/genetics, RNA Splicing, Retina/metabolism, Retinal Dystrophies/genetics, Retinal Dystrophies/physiopathology, AON-mediated exon skipping, CEP290, Flanders founder c.4723A > Leber congenital amaurosis and allied retinal ciliopathies, T nonsense mutation, lcsh:Genetics, 030104 developmental biology, chemistry, RNA splicing, Retinal Dystrophies

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d1b3289409a8e17d29649a47b30231
https://www.mdpi.com/2073-4425/10/5/368

المؤلفون: Andrew T. Watt, Michael E. Østergaard, Pawan Kumar, Pawan K. Sharma, Punit P. Seth, Josh G. Nichols, Poul Nielsen

المصدر: Østergaard, M E, Kumar, P, Nichols, J, Watt, A, Sharma, P K, Nielsen, P & Seth, P P 2015, ' Allele-Selective Inhibition of Mutant Huntingtin with 2-Thio-and C5-Triazolylphenyl-Deoxythymidine-Modified Antisense Oligonucleotides ', Nucleic Acid Therapeutics, vol. 25, no. 5, pp. 266-274 . https://doi.org/10.1089/nat.2015.0547

مصطلحات موضوعية: Thymidine/analogs & derivatives, Oligonucleotides, Antisense/genetics, Huntingtin, RNase P, Mutant, Ribonuclease H, Nerve Tissue Proteins, Biology, Biochemistry, Drug Discovery, Genetics, Huntingtin Protein, Nerve Tissue Proteins/genetics, Humans, RNase H, Molecular Biology, Base Pairing, Alleles, RNA Cleavage, Messenger RNA, DNA Repeat Expansion, Ribonuclease H/physiology, Base Sequence, Oligonucleotide, RNA, Oligonucleotides, Antisense, Molecular biology, biology.protein, Molecular Medicine, Mutant Proteins, Mutant Proteins/genetics, Thymidine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b13b9c3fad6a832bc3a891027d83f039
https://pubmed.ncbi.nlm.nih.gov/26222265

المؤلفون: Jean-Dominique Vassalli, Béatrice Conne, Dominique Belin, Joachim Huarte, Pascale Gubler, Andre Stutz

المصدر: Molecular and Cellular Biology, Vol. 17, No 4 (1997) pp. 1759-1767

مصطلحات موضوعية: Protein Biosynthesis/drug effects, Untranslated region, Tissue Plasminogen Activator/biosynthesis/genetics, Polyadenylation, Molecular Sequence Data, Gene Expression Regulation/drug effects, RNA, Messenger/ genetics/metabolism, Biology, Oligonucleotides, Antisense/ genetics/pharmacology, Mice, Meiosis/drug effects/genetics, Protein biosynthesis, Animals, Gene silencing, Coding region, RNA, Messenger, Molecular Biology, ddc:616, Regulation of gene expression, Messenger RNA, Base Sequence, Translation (biology), Cell Biology, Oligonucleotides, Antisense, Molecular biology, Oocytes/drug effects/growth & development/ metabolism, Meiosis, Gene Expression Regulation, Protein Biosynthesis, Tissue Plasminogen Activator, Oocytes, Female, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1955c163514b54683b079aabe8a592ec
https://doi.org/10.1128/mcb.17.4.1759

المؤلفون: Skorski T, Szczylik C, Ratajczak MZ, Malaguarnera L, Gewirtz AM, CALABRETTA, Bruno

المساهمون: Skorski, T, Szczylik, C, Ratajczak, Mz, Malaguarnera, L, Gewirtz, Am, Calabretta, Bruno

مصطلحات موضوعية: Growth Substances/pharmacology, Hematopoiesis/drug effect, Oligonucleotides Antisense/genetics

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/pmid/1371302; info:eu-repo/semantics/altIdentifier/wos/WOS:A1992HF64000013; volume:175; firstpage:743; lastpage:750; journal:JOURNAL OF EXPERIMENTAL MEDICINE; http://hdl.handle.net/11380/811724; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-0026522525

الاتاحة: http://hdl.handle.net/11380/811724

المؤلفون: Nielsen, P E

المصدر: Ugeskrift for Laeger. 160(36):5171

المؤلفون: Eva van Rooij, H Siga, Alejandro Hidalgo, Susanne Pehrsson, Ralph Knöll, Niels Grote Beverborg, Qing-Dong Wang, Magdalena Zurek, Rudolf A. de Boer, Regina Fritsche-Danielson, Kenny M. Hansson, Michael Frisk, Sagar S. Damle, Adam E. Mullick, Martijn F Hoes, Daniela Später, Tim R Eijgenraam, Kenneth R. Chien, Malin Palmér, Steve T Yeh, Herman H W Silljé, Cornelis J. Boogerd, William E. Louch, Tamsin Albery, Nils Bomer, Peter van der Meer, Zaher Elbeck

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research, Cardiovascular Centre (CVC), Restoring Organ Function by Means of Regenerative Medicine (REGENERATE)

المصدر: Nature Communications, 12(1). Nature Publishing Group
Nature Communications, 12(1):5180. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications

مصطلحات موضوعية: Male, Oligonucleotides, Antisense/genetics, Cardiomyopathy, Oligonucleotides, General Physics and Astronomy, Inbred C57BL, Mice, Myocytes, Cardiac, Myocardial infarction, Multidisciplinary, Inbred Lew, Dilated cardiomyopathy, Myocytes, Cardiac/metabolism, Phospholamban, Cardiac/metabolism, Female, Cardiomyopathies, Cardiac function curve, endocrine system, Calcium/metabolism, Science, Ischemia, Cardiomyopathies/genetics, Drug development, Article, General Biochemistry, Genetics and Molecular Biology, Heart Failure/genetics, Downregulation and upregulation, medicine, Animals, Humans, Heart Failure, Myocytes, Calcium-Binding Proteins/genetics, business.industry, Calcium-Binding Proteins, General Chemistry, Genetic Therapy, Translational research, Oligonucleotides, Antisense, medicine.disease, Rats, Mice, Inbred C57BL, Rats, Inbred Lew, Heart failure, Cancer research, Antisense/genetics, Calcium, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b1c61196b5213b6893b0391ecf26eb

المؤلفون: Grote Beverborg, Niels, Später, Daniela, Knöll, Ralph, Hidalgo, Alejandro, Yeh, Steve T, Elbeck, Zaher, Silljé, Herman H W, Eijgenraam, Tim R, Siga, Humam, Zurek, Magdalena, Palmér, Malin, Pehrsson, Susanne, Albery, Tamsin, Bomer, Nils, Hoes, Martijn F, Boogerd, Cornelis J, Frisk, Michael, van Rooij, Eva, Damle, Sagar, Louch, William E, Wang, Qing-Dong, Fritsche-Danielson, Regina, Chien, Kenneth R, Hansson, Kenny M, Mullick, Adam E, de Boer, Rudolf A, van der Meer, Peter

المصدر: Nature Communications vol.12 (2021) date: 2021-08-30 nr.1 p.5180 [ISSN 2041-1723]

مصطلحات الفهرس: Animals, Calcium/metabolism, Calcium-Binding Proteins/genetics, Cardiomyopathies/genetics, Female, Genetic Therapy, Heart Failure/genetics, Humans, Male, Mice, Mice, Inbred C57BL, Myocytes, Cardiac/metabolism, Oligonucleotides, Antisense/genetics, Rats, Rats, Inbred Lew, Artikel, Article

URL: https://pure.knaw.nl/portal/en/publications/f78e43e5-e9ae-42a4-92c4-d048393f46c9

المؤلفون: Rouas, Redouane, Fayyad Kazan, Hussein, El Zein, Nabil, Lewalle, Philippe, Rothé, Françoise, Simion, Alexandru, Akl, Haidar, Mourtada, Mohamad, El Rifai, Mohamad, Burny, Arsène, Romero, Pedro, Martiat, Philippe, Badran, Bassam

المصدر: European Journal of Immunology, 39 (6

مصطلحات الفهرس: Sciences bio-médicales et agricoles, 3' Untranslated Regions -- genetics, 3' Untranslated Regions -- metabolism, CD4-Positive T-Lymphocytes -- metabolism, Fetal Blood -- cytology, Forkhead Transcription Factors -- genetics, Gene Expression -- genetics, Gene Expression Profiling, Gene Expression Regulation, Hela Cells, Humans, Lentivirus -- genetics, MicroRNAs -- antagonists & inhibitors, MicroRNAs -- genetics, MicroRNAs -- metabolism, Oligonucleotides, Antisense -- genetics, T-Lymphocyte Subsets -- metabolism, T-Lymphocytes, Regulatory -- metabolism, Transduction, Genetic, Human, MicroRNA, Treg, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article

URL: https://dipot.ulb.ac.be/dspace/bitstream/2013/50984/3/50984.pdf
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/50984
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL

المؤلفون: Schoenfelder, Stefan, Smits, Guillaume, Fraser, Peter, Reik, Wolf, Paro, Renato

المصدر: EMBO reports, 8 (11

مصطلحات الفهرس: Sciences biomédicales, Animals, Animals, Genetically Modified, Drosophila melanogaster -- genetics -- metabolism, Gene Silencing, Genes, Reporter, Genomic Imprinting, Mice, Oligonucleotides, Antisense -- genetics -- metabolism, RNA Interference, RNA, Long Noncoding, RNA, Untranslated -- genetics -- metabolism, Regulatory Sequences, Nucleic Acid, Transcription, Genetic, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article

URL: https://dipot.ulb.ac.be/dspace/bitstream/2013/172685/5/172685.pdf
https://dipot.ulb.ac.be/dspace/bitstream/2013/172685/6/PMC2247386.pdf
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/172685
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL

المؤلفون: Willard-Gallo, Karen, Burny, Arsène, Furtado, Manohar, Wolinsky, Steven M.

المصدر: European Journal of Immunology, 31 (4

مصطلحات الفهرس: Allergie et immunopathologie, Immunologie, Antigens, CD3 -- metabolism, Cell Line, Dose-Response Relationship, Drug, Down-Regulation, Flow Cytometry, Gene Expression Regulation, Viral, Gene Products, nef -- genetics -- metabolism, Gene Products, rev -- genetics -- metabolism, Gene Products, tat -- genetics -- metabolism, HIV Core Protein p24 -- metabolism, HIV-1 -- genetics -- growth & development -- physiology, Humans, Oligonucleotides, Antisense -- genetics, RNA, Messenger -- genetics -- metabolism, RNA, Viral -- genetics -- metabolism, Receptors, Antigen, T-Cell -- metabolism, Reverse Transcriptase Polymerase Chain Reaction, Signal Transduction, T-Lymphocytes -- metabolism -- virology, Time Factors, nef Gene Products, Human Immunodeficiency Virus, rev Gene Products, Human Immunodeficiency Virus, tat Gene Products, Human Immunodeficiency Virus, CD3-γ, HIV, TCR, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article

URL: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/189784
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL

المؤلفون: Vaerman, J L, Moureau, P., Deldime, F, Lewalle, Philippe, Lewalle, Clarisse, Morschhauser, F, Martiat, Philippe

المصدر: Blood, 90 (1

مصطلحات الفهرس: Sciences bio-médicales et agricoles, Cell Division -- drug effects, Cell Division -- genetics, Fusion Proteins, bcr-abl -- genetics, Hematopoietic Stem Cells -- cytology, Hematopoietic Stem Cells -- drug effects, Humans, Leukemia -- genetics, Leukemia -- pathology, Oligonucleotides, Antisense -- genetics, Oligonucleotides, Antisense -- pharmacology, Thionucleotides -- genetics, Thionucleotides -- pharmacology, Tumor Cells, Cultured, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article

URL: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/59403
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL