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المؤلفون: Keita Sasaki, Akifumi Kyuno, Shunji Haruta, Yuji Sasaki, Akihide Tanimoto, Yusuke Torikai
المصدر: Journal of Pharmaceutical Sciences
مصطلحات موضوعية: Nasal cavity, MRI, Magnetic resonance imaging, Mn, Manganese, Pharmaceutical Science, Controlled delivery, 02 engineering and technology, Pharmaceutics, Drug Delivery and Pharmaceutical Technology, 030226 pharmacology & pharmacy, Mice, IgA, Immunoglobulin A, 0302 clinical medicine, MAD, Mucosal atomization device, Controlled release, IM, Intramuscular, SEM, Scanning electron microscopy, Respiratory system, MALT, Mucosa-associated lymphoid tissue, Mice, Inbred BALB C, IgG, Immunoglobulin G, OVA, Ovalbumin, 3D, Three dimensions, biology, Immunogenicity, Antibody titer, respiratory system, 021001 nanoscience & nanotechnology, Mucosal vaccination, PBS, Phosphate-buffered saline, medicine.anatomical_structure, CT, Computed tomography, Powder technology, Powders, Nasal drug delivery, TMB, 3, 3′, 5, 5′- tetramethylbenzidine, 0210 nano-technology, Ovalbumin, Drug delivery system, NALT, Nasopharyngeal-associated lymphoid tissue, 03 medical and health sciences, BSA, Bovine serum albumin, Immune system, Adjuvants, Immunologic, Antigen, otorhinolaryngologic diseases, medicine, Animals, Distribution (pharmacology), MEMRI, Manganese-enhanced magnetic resonance imaging, Immunity, Mucosal, Administration, Intranasal, HE, Hematoxylin and eosin, business.industry, Macaca fascicularis, Formulation, Immunology, SIgA, Secretory immunoglobulin A, biology.protein, Mucoadhesive, business, Vaccine
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المؤلفون: Roland El Ghazal, So Young Kim, Scott C. Johns, Purva Gupta, Mark M. Fuster, Elina I. Zuniga
المصدر: Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 2, Pp 86-97 (2020)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.), vol 22, iss 2مصطلحات موضوعية: 0301 basic medicine, CD4-Positive T-Lymphocytes, Cancer Research, T-Lymphocytes, Ova, Ovalbumin, CD8-Positive T-Lymphocytes, Major Histocompatibility Complex, chemistry.chemical_compound, Carcinoma, Lewis Lung, Mice, 0302 clinical medicine, HS, Heparan sulfate, Loss of Function Mutation, Cytotoxic T cell, HSPG, Heparan sulfate proteoglycan, LysM, M Lysozyme locus, LPS, Lipopolysaccharide, Immunity, Cellular, biology, Chemistry, Heparan sulfate, Treg, Regulatory T cell, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, DC, Dendritic cell, 3. Good health, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Proteoglycans, Sulfotransferases, Original article, T cell, Clinical Sciences, Antigen presentation, TIL, Tumor Infiltrating Lymphocyte, Major histocompatibility complex, lcsh:RC254-282, TcR, T cell receptor, 03 medical and health sciences, Sdc, Syndecan, Immune system, Lymphocytes, Tumor-Infiltrating, Antigen, Polysaccharides, medicine, CD11c, CD11c locus, Animals, Humans, Oncology & Carcinogenesis, MHC, Major histocompatibility complex, Histocompatibility Antigens Class I, BMDCs, Bone marrow dendritic cells, Dendritic Cells, Molecular biology, CD11c Antigen, 030104 developmental biology, Ndst, N-deacetylase/N-sulfotransferase, biology.protein, LLC, Lewis lung carcinoma, SIINFEKL, Ova peptide sequence for Ova257 Ova264, Heparitin Sulfate, CD8
وصف الملف: application/pdf
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المؤلفون: Hideki Kakutani, Tomohiro Yuzuriha, Teruyuki Nakao, Souichi Ohta
المصدر: Toxicology Reports
Toxicology Reports, Vol 9, Iss, Pp 53-57 (2022)مصطلحات موضوعية: IL-17, interleukin-17, TCDD, 2,3,7,8-tetrachlorobibenzo-p-dioxin, IL-13, interleukin-13, Health, Toxicology and Mutagenesis, Regular Article, IL-10, interleukin-10, Subclinical oral exposure of TCDD, Toxicology, Ig, immunoglobulin, OVA-specific antibody titer, EROD, ethoxyresorufin O-deethylase, OVA, ovalbumin, 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), IL-2, interleukin-2, RA1190-1270, AhR, aryl hydrocarbon receptor, Toxicology. Poisons, TDI, tolerable daily intake, IL-4, interleukin-4, heterocyclic compounds, IFN-γ, interferon-gamma, ComputingMethodologies_COMPUTERGRAPHICS
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المؤلفون: Seyyed Shamsadin Athari, Minmin Huang, Entezar Mehrabi Nasab
المصدر: Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 12, Pp 6957-6962 (2021)مصطلحات موضوعية: OPA1, Mitochondrial dynamin like GTPase, Allergy, AHR, Airway hyperresponsiveness, IT, Intratrachea administration, MFN, Mitofusin, Cytb, Cytochrome b, MSC, mesenchymal stem cell, Mitochondrion, Ig, Immunoglobulin, PGE2, Prostaglandin E2, IP, Intraperitoneal injection, MSC/IV, mesenchymal stem cell intravenous injection, MSC/BI, mesenchymal stem cell bronchial administration, IL, Interleukin, Biology (General), PGC1a, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, BM, Bone marrow, H&E, Haemotoxylin and eosin, OVA, Ovalbumin, FIS1, Mitochondrial fission 1 protein, Cys-LT, Cysteinyl Leukotriene, respiratory system, TGF, Transforming growth factor, PBS, Phosphate-buffered saline, IFN, Interferon, HLA, Human leukocyte antigen, medicine.anatomical_structure, ELISA, Enzyme-linked immunosorbent assay, Original Article, ATP, Adenosine triphosphate, medicine.symptom, Signal transduction, CD, Cluster of differentiation, General Agricultural and Biological Sciences, MIP, macrophage inflammatory protein, PAS, Periodic-acid-Schiff, MMP, Matrix metalloproteinase, TFAM, Transcription factor A mitochondrial, QH301-705.5, Inflammation, COX, Cyclooxygenase, NO, Nitric oxide, MSC, iPSC, induced pluripotent stem cells, Nrf, Nuclear erythroid 2 p45-related factor, CCL, Chemokine (C-C motif) ligand, medicine, BALF, Bronchoalveolar lavage fluid, LT, Leukotriene, Th, T helper, Asthma, ComputingMethodologies_COMPUTERGRAPHICS, Goblet cell, Drp1, Mitochondrial fission depends on the cytosolic GTPase dynamin-related protein 1, business.industry, Mesenchymal stem cell, TNF, Tumor necrosis factor, Eosinophil, HGF, Hepatocyte growth factor, medicine.disease, Mucus, respiratory tract diseases, HO, Heme oxygenase, Immune system, IDO, Indoleamine 2,3-dioxygenase, Immunology, business, ND1, NADH-ubiquinone oxidoreductase chain 1, ROS, Reactive oxygen species
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المؤلفون: Seyyed Shamsadin Athari, Dong Wang, Entezar Mehrabi Nasab
المصدر: Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 8, Pp 4311-4317 (2021)مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, MAP, mitogen-activated protein, NF-κB, the nuclear factor-κB, AP-1, activator protein 1, Pharmacology, 01 natural sciences, Chitosan, Pathogenesis, chemistry.chemical_compound, PAS, periodic acid–schiff, Biology (General), BBB, blood–brain barrier, BALf, bronchoalveolar lavage fluid, media_common, TNF, tumor necrosis factor, Nano, respiratory system, AHR, airway hyperresponsiveness, medicine.anatomical_structure, ELISA, the enzyme-linked immunosorbent assay, iNOS, inducible nitric oxide synthase, AB, alcian blue, Original Article, medicine.symptom, IP, intraperitoneal, MTT, The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide, General Agricultural and Biological Sciences, Drug, QH301-705.5, IT, intratracheal, media_common.quotation_subject, E-B-NP, encapsulated-Baicalein-nanoparticles, Inflammation, Th, T lymphocyte helper, OVA, ovalbumin, 03 medical and health sciences, mV, millivolt, medicine, PG, prostaglandin, L-B-NP, loaded-Baicalein-nanoparticles, ComputingMethodologies_COMPUTERGRAPHICS, Asthma, Lung, MCh, methacholine, medicine.disease, Mucus, IL, interleukin, respiratory tract diseases, Baicalein, COX, cyclooxygenase, Airway, 030104 developmental biology, chemistry, FT-IR, fourier-transform infrared spectroscopy, nm, nanometer, Flavonoid, H&E, hematoxylin and eosin, 010606 plant biology & botany
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المؤلفون: Marco A. Ramos, Ruth Heidelberger, Roberto J. Alcazar-Felix, Roberto Adachi, Eduardo I. Cardenas, Alan R. Burns, Alejandro I. Rodarte, Ricardo Treviño González, Rodolfo A. Cardenas, Alejandro Isaza, Elizabeth Sanchez
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, CTMC, connective tissue MC, GS, series conductance, CAE, chloroacetate esterase, DNP, 2,4-dinitrophenol, CTX, cholera toxin, GTPγS, guanosine 5′-3-O-(thio)triphosphate, Biochemistry, Wsh, MC-deficient KitW-sh/W-sh mouse, Abnormal platelet morphology, Mice, Gm, membrane conductance, MC, mast cell, MMC, mucosal MC, bm, basement membrane, DT, diphtheria toxin, PCMCs, peritoneal-cell-derived MCs, BMMCs, bone-marrow-derived MCs, Platelet, Mast Cells, MFI, mean fluorescence intensity, Munc, mammalian homolog of C. elegans uncoordinated gene, Mice, Knockout, Chemistry, Degranulation, Qb-SNARE Proteins, Cm, membrane capacitance, Mast cell, humanities, Cell biology, Vesicle-associated membrane protein, medicine.anatomical_structure, F, farad, Stx, syntaxin, Connective Tissue, Pf4, platelet factor 4, SNARE, soluble N-ethylmaleimide-sensitive factor attachment protein receptors, ΔCm, capacitance gain, platelets, SNAP23, AU, arbitrary units, exocytosis, Research Article, Blood Platelets, PMA, phorbol 12-myristate 13-acetate, S, siemens, SNARE proteins, FSC, forward scatter, Connective tissue, Exocytosis, 03 medical and health sciences, OVA, ovalbumin, mMCP5/Mcpt5, mouse mast cell protease 5, MOV, mean object volume, medicine, anaphylaxis, Animals, Fura-2 AM, Fura-2-acetoxymethyl ester, Qc-SNARE Proteins, Syt, synaptotagmin, Molecular Biology, 030102 biochemistry & molecular biology, SNAP23, synaptosomal-associated protein of 23 KDa, SCF, stem cell factor, Secretory Vesicles, RBL-2H3, rat basophilic leukemia cell line, Cell Biology, Cma1, chymase 1, allergy, Sv, surface density, VAMP, vesicle-associated membrane protein, 030104 developmental biology, B6, C57BL6/J mouse line, mast cell, Platelet factor 4, HSA, human serum albumin, Vv, volume density
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المؤلفون: Guangyi Ba, Weitian Zhang, Hai Lin, Ru Tang, Mingxian Li
المصدر: World Allergy Organization Journal, Vol 13, Iss 10, Pp 100473-(2020)
The World Allergy Organization Journalمصطلحات موضوعية: Th2, Type 2T helper, Pulmonary and Respiratory Medicine, lcsh:Immunologic diseases. Allergy, IHC, Immunohistochemistry, Thioredoxin-Interacting Protein, Ovalbumin, Immunology, NAC, N-acetylcysteine, Pharmacology, Resveratrol, AR, Allergic rhinitis, Immunoglobulin E, Article, SOD, Superoxide dismutase, Allergic rhinitis, Proinflammatory cytokine, Superoxide dismutase, chemistry.chemical_compound, medicine, Immunology and Allergy, NLF, Nasal lavage fluid, MDA, Malondialdehyde, OVA, Ovalbumin, biology, business.industry, Eosinophil, respiratory system, ELISA, Enzyme-linked immunosorbent assay, medicine.anatomical_structure, chemistry, Oxidative stress, biology.protein, business, Reactive oxygen species, lcsh:RC581-607, TXNIP, TXNIP, Thioredoxin-interacting protein, ROS, Reactive oxygen species
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المؤلفون: Daniel W.S. Tan, Fred W.S. Wong, Dorothy H.J. Cheong, Thai Tran
المصدر: Pharmacological Research
مصطلحات موضوعية: CTX, cyclophosphamide, STAT, signal transducers and activators of transcription, Artesunate (PubChem CID:156252), HDAC2, histone deacetylase 2, Pharmacology, Nrf2, nuclear factor erythroid 2-related factor 2, TNF, tumour necrosis factor, SLE, systemic lupus erythematosus, VCAM-1, vascular cell adhesion molecule 1, 0302 clinical medicine, eos, eosinophil, GSH, glutathione, 3-NT, 3-nitrotyrosine, Medicine, IκBα, inhibitor of NF-κB alpha, Th17, T helper 17, HO-1, heme oxygenase-1, ICAM-1, intercellular adhesion molecule 1, chemistry.chemical_classification, XIAP, X-linked inhibitor of apoptosis protein, YKL-40, chitinase-like glycoprotein, Chemical compounds studied in this article Artemisinin (PubChem CID: 68827), MCP-1, monocyte chemoattractant protein-1, HIF-1α, hypoxia-inducible factor 1-alpha, Artemisinins, DHA, dihydroartemisinin, GLUT, glucose transporter, HELF, human embryonic lung fibroblasts, RNAi, RNA interference, VDAC2, voltage-dependent anion channel 2, 030220 oncology & carcinogenesis, COX-2, cyclooxygenase-2, LADPI, liposomal artesunate dry powder inhalers, behavior and behavior mechanisms, iNOS, inducible nitric oxide synthase, IP-10, IFNγ-induced protein 10, 8-iso, 8-isoprostane, psychological phenomena and processes, Foxo1, forkhead box O1, KDR/flk-1, kinase insert domain receptor /fetal liver kinase-1, education, H2AX, H2A histone family member X, PCNA, proliferating cell nuclear antigen, Pneumonia, Viral, MIP-2, macrophage inflammatory protein 2, mTOR, mammalian target of rapamycin, ACE2, angiotensin-converting enzyme 2, Antiviral Agents, Article, 4EBP1, eukaryotic translation initiation factor 4E-binding protein 1, 03 medical and health sciences, LD50, lethal dose, Betacoronavirus, ARTD, artemisinin-daumone hybrid 15, BDHA, biotinylated dihydroartesunate, PGE2, prostaglandin E2, TGF, tumour growth factor, Humans, DHA-NLC, dihydroartemisinin-nanostructured lipid carriers, u-PA, urokinase-type plasminogen activator, TSLP, thymic stromal lymphopoietin, E2F1, E2F transcription factor 1, LLC, lewis lung carcinoma, PEG, polyethylene glycol, MDA, malondialdehyde, NO, nitric oxide, hsp47, heat shock protein 47, Arteether (PubChem CID: 3000469), medicine.disease, IL, interleukin, 030104 developmental biology, Mcl-1, myeloid cell leukemia-1, cell proliferation, chemistry, COPD, chronic obstructive pulmonary disease, Smac, second mitochondrial activator of caspases, Treg, regulatory T, artemisinin, Apoptosis, NQO1, NAD(P)H quinone dehydrogenase 1, CSE, cigarette smoke extract, Malaria, 0301 basic medicine, Lung Diseases, Lymp, lymphocyte, Respiratory diseases, ALI, acute lung injury, DLAedried, leaf artemisia extract, MPO, myeloperoxidase, 8-OHdG, 8-hydroxy-2’-deoxyguanosine, AP-1, activator protein 1, LMVD, lymphatic microvessel density, TLR4, toll-like receptor 4, 2DG, 2-Deoxy-D-glucose, chemistry.chemical_compound, Artemether (PubChem CID: 68911), DNA, deoxyribonucleic acid, SCLC, small cell lung cancer, KC, keratinocyte chemoattractant, BALF, bronchoalveolar lavage fluid, Artemisinin, Rb, retinoblastoma, ABCG2, ATP-binding cassette subfamily member 2, NF-κB, nuclear factor-kappa B, CDK, cyclin-dependent kinase, ATF3, activating transcription factor 3, GPx, glutathione peroxidase, INF, interferon, CDDP, cisplatin, RA, FLS rheumatoid arthritis fibroblast-like synoviocytes, [Ca2+]i, intracellular calcium ion, NOX, NADPH oxidase, RIR, renal ischemia reperfusion, VEGF, vascular endothelial growth factor, Vascular endothelial growth factor, MMP, matrix metalloproteinase, AHR, airway hyperresponsiveness, JNK, c-Jun N-terminal kinase, shRNA, short hairpin RNA, LPS, lipopolysaccharide, medicine.symptom, EMT, epithelial-mesenchymal transition, Coronavirus Infections, NKD2, naked cuticle homolog 2, PI3K, phosphoinositide 3-kinase, Artemisitene (PubChem CID: 11000442), medicine.drug, AEC, alveolar epithelial cells, GSK3β, glycogen synthase kinase 3 beta, NPC, nasopharyngeal carcinoma, ATP, adenosine triphosphate, Dihydroartemisinin (PubChem CID: 139073990), Inflammation, neu, neutrophil, lung, ER, endoplasmic reticulum, OVA, ovalbumin, ROS, reactive oxygen species, RANKL, receptor activator of nuclear factor kappa-B ligand, NSCLC, non-small cell lung cancer, SOD, superoxide dismutase, parasitic diseases, TIMP, tissue inhibitor of metalloproteinases, Ym2, chitinase 3-like protein 4, HNF4A, hepatocyte nuclear factor 4 alpha, Pandemics, Mac, macrophage, Reactive oxygen species, HCMV, human cytomegalovirus, NLRP3, NLR family pyrin domain containing 3, business.industry, Cell growth, SARS-CoV-2, COVID-19, ASC, apoptosis-associated speck-like protein containing CARD, EGFR, epidermal growth factor receptor, AIF, apoptosis-inducing factor, MAPK, mitogen-activated protein kinases, inflammation, Keap1, kelch-like ECH-associated protein 1, Axin2, axis inhibition protein 2, business, sm-α, actin smooth muscle-α actin
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المؤلفون: Gene J. Pirelli, Gerd Bobe, William R. Vorachek, Jean A. Hall, K. Denise Apperson, Brian P. Dolan
المصدر: Journal of Trace Elements in Medicine and Biology
مصطلحات موضوعية: 0301 basic medicine, TrxR, thioredoxin reductase, Selenium-enriched alfalfa hay, Ovalbumin, Animal feed, WB, whole blood, Beef cattle, Biochemistry, Article, MW, molecular weight, Intestinal absorption, Inorganic Chemistry, OVA, ovalbumin, TMB, 3, 3’, 5, 5’-tetramethyl benzidine, 03 medical and health sciences, Animal science, Pregnancy, ICP-MS, inductively coupled argon plasma emission spectroscopy, Pregnant beef cows, medicine, Animals, Newborn beef calves, Passive transfer, biology, 0402 animal and dairy science, food and beverages, 04 agricultural and veterinary sciences, medicine.disease, Animal Feed, Ig, immunoglobulin, 040201 dairy & animal science, 030104 developmental biology, Animals, Newborn, In utero, biology.protein, Molecular Medicine, Colostrum, Gestation, Cattle, Female, T-TBS, Tween-Tris buffered saline, Medicago sativa
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المؤلفون: Nur Salme Suhana Shamshuddin, Rozaini Mohd Zohdi
المصدر: Journal of Traditional and Complementary Medicine, Vol 8, Iss 1, Pp 39-45 (2018)
Journal of Traditional and Complementary Medicineمصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, DXN, Dexamethasone, Ovalbumin, PBS, Phosphate buffered saline, Allergic asthma, lcsh:Medicine, Pharmacology, Anti-inflammatory, PAS, Periodic acid Schiff, 03 medical and health sciences, Mice, 0302 clinical medicine, medicine, BALF, Bronchoalveolar lavage fluid, Ingestion, i.p., Intraperitoneal injection, Dexamethasone, medicine.diagnostic_test, biology, OVA, Ovalbumin, business.industry, lcsh:R, Honey, Mast cell, Mucus, Epithelium, 030104 developmental biology, Bronchoalveolar lavage, medicine.anatomical_structure, Complementary and alternative medicine, 030220 oncology & carcinogenesis, Immunology, biology.protein, Original Article, business, medicine.drug
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المؤلفون: Ametria Harrison, Randal K. Gregg, Nathan Gentry, Ashley Corey, Jillian Bradley
المصدر: Cellular Immunology
مصطلحات موضوعية: 0301 basic medicine, Macrophage, THP-1 Cells, medicine.medical_treatment, medicine.disease_cause, Antibodies, Viral, Monocytes, Ebola virus, APC, allophycocyanin, EBOV, Zaire ebolavirus, VLPs, virus-like particles, chemistry.chemical_classification, TNF, tumor necrosis factor, biology, Viral immune evasion, Chemotaxis, Ebolavirus, Cytokine, Integrin alpha M, sGP, secreted glycoprotein, LPS, lipopolysaccharide, Cytokines, Tumor necrosis factor alpha, FITC, fluorescein isothiocyanate, TLR, Toll-like receptor, PMA, phorbol 12-myristate 13-acetate, Phagocytosis, 030106 microbiology, Immunology, CD, cluster of differentiation, Macrophage polarization, Antiviral Agents, Article, 03 medical and health sciences, OVA, ovalbumin, Viral Proteins, PBS, phosphate buffered saline, medicine, TACE, tumor necrosis factor-alpha converting enzyme, Humans, Glycoproteins, Macrophages, Hemorrhagic Fever, Ebola, IL, interleukin, 030104 developmental biology, chemistry, biology.protein, Secreted glycoprotein, Glycoprotein, GP, glycoprotein
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المؤلفون: Shingo Eikawa, Kouji Hase, Yukihiro Furusawa, Heiichiro Udono, Takenori Uehara, Shohei Hori, Yuki Kunisada, Shohei Domae, Nahoko Tomonobu, Akira Sasaki
المصدر: EBioMedicine
EBioMedicine, Vol 25, Iss C, Pp 154-164 (2017)مصطلحات موضوعية: 0301 basic medicine, lcsh:Medicine, TIL, tumor infiltrating lymphocyte, mTORC1, T-Lymphocytes, Regulatory, Glut1, glucose transporter 1, Foxp3, forkhead box P3, 0302 clinical medicine, AMP-activated protein kinase, APC, allophycocyanin, AMP-Activated Protein Kinase Kinases, Neoplasms, Tumor immunity, CTLA4, cytotoxic T-lymphocyte-4, Tumor Microenvironment, OCR, oxygen consumption rate, CTLA-4 Antigen, IL-2 receptor, Receptors, Immunologic, KLRG1, killer cell lectin-like receptor G1, GFP, green fluorescent protein, education.field_of_study, lcsh:R5-920, Glucose Transporter Type 1, OVA, Ovalbumin, TMRE, tetramethylrhodamine ethyl ester, FOXP3, hemic and immune systems, IL-10, interleukin-10, CC, compound C, Cell Differentiation, Forkhead Transcription Factors, General Medicine, Metformin, Interleukin-10, Interleukin 10, Treg, T regulatory cell, 030220 oncology & carcinogenesis, TCR, T cell antigen receptor, mTOR, FCCP, Carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone, potent mitochondrial oxidative phosphorylation uncoupler, FITC, fluorescein isothiocyanate, lcsh:Medicine (General), Glycolysis, Integrin alpha Chains, Research Paper, Met, metformin, CD103, Cluster Designation 103, Integrin αE, RA, rapamycin, FSC, forward scatter, Population, chemical and pharmacologic phenomena, T2D, type 2 diabetes, mTOR, mammalian target of rapamycin, Biology, Regulatory T cell (Treg), Mechanistic Target of Rapamycin Complex 1, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Antigens, CD, Humans, Lectins, C-Type, iTreg, inducible T regulatory cell, education, Ti-Treg, tumor infiltrating-T regulatory cell, Sirolimus, Tumor microenvironment, ECAR, extracellular acidification rate, CFSE, carboxyfluorescein diacetate succinimidyl ester, lcsh:R, AMPK, CTV, cell trace violet, TGF-β, Transforming growth factor-β1, PE, phycoerythrin, SSC, side scatter, AMPK, AMP-activated protein kinase, 030104 developmental biology, Gene Expression Regulation, biology.protein, Cancer research, Trans-Activators, Protein Kinases, FAO, fatty acid oxidation, ROS, Reactive oxygen species
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المؤلفون: Yoshinori Yamanishi, Masashi Minami, Tomoyuki Bando, Naoko Nagano, Hajime Karasuyama, Setsuko Fujita, Soichiro Yoshikawa
المصدر: Biochemistry and Biophysics Reports, Vol 10, Iss C, Pp 82-87 (2017)
Biochemistry and Biophysics Reportsمصطلحات موضوعية: 0301 basic medicine, Cell type, LTB4, leukotriene B4, Biophysics, Stimulation, chemical and pharmacologic phenomena, Immunoglobulin E, Biochemistry, lcsh:Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Immune system, LTA4, leukotriene A4, HETE, hydroxyeicosatetraenoic acid, parasitic diseases, PGE2, prostaglandin E2, lcsh:QD415-436, Celecoxib (PubChem CID: 2662), LC-MS/MS, lcsh:QH301-705.5, LOX, lipoxygenase, BW-A4C (PubChem CID: 6438354), biology, BMBAs, bone marrow derived basophils, OVA, Ovalbumin, Chemistry, Effector, hemic and immune systems, Lipid signaling, LTD4, leukotriene D4, SC-560 (PubChem CID: 4306515), COX-2, Basophils, Interleukin 33, COX, cyclooxygenase, 030104 developmental biology, lcsh:Biology (General), TNP, 2,4,6-trinitrophenyl, Immunology, biology.protein, PGD2, prostaglandin D2, Mast cells, Prostaglandins, Eicosanoids, LTC4, leukotriene C4, Histamine, Research Article, BMMCs, bone marrow derived mast cells
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المؤلفون: Tomoharu Yokooji, Takanori Taogoshi, Naoki Ninomiya, Eishin Morita, Yukinori Yamada, Hiroaki Matsuo
المصدر: Biochemistry and Biophysics Reports, Vol 20, Iss, Pp-(2019)
Biochemistry and Biophysics Reportsمصطلحات موضوعية: 0301 basic medicine, ω5-Gliadin, medicine.disease_cause, Immunoglobulin E, Ab, antibody, Biochemistry, 0302 clinical medicine, Allergen, lcsh:QD415-436, lcsh:QH301-705.5, Sensitization, chemistry.chemical_classification, biology, HRP, horseradish peroxidase, food and beverages, Wheat allergy, medicine.anatomical_structure, Allergenicity, 030220 oncology & carcinogenesis, Anaphylaxis, Research Article, BN, Brown-Norway, Biophysics, PBS, phosphate-buffered saline, digestive system, lcsh:Biochemistry, 03 medical and health sciences, OVA, ovalbumin, medicine, ELISA, enzyme linked immunosorbent assay, 1BS-18, hypoallergenic wheat lacking ω5-gliadin, business.industry, Hypoallergenic wheat, PBS-T, phosphate-buffered saline contining 0.1% Tween 20, nutritional and metabolic diseases, Hypoallergenic, medicine.disease, Gluten, Ig, immunoglobulin, digestive system diseases, QOL, quality of life, 030104 developmental biology, chemistry, lcsh:Biology (General), Immunology, biology.protein, Rat, WDEIA, wheat-dependent exercise-induced anaphylaxis, business, Gliadin
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المؤلفون: Tin-Tin Win-Shwe, Rie Yanagisawa, Eiko Koike, Hirohisa Takano
المصدر: Toxicology Reports
Toxicology Reports, Vol 6, Iss, Pp 1253-1262 (2019)مصطلحات موضوعية: Chemokine, ER, estrogen receptor, Health, Toxicology and Mutagenesis, Allergic asthma, 010501 environmental sciences, Toxicology, Immunoglobulin E, 01 natural sciences, 0302 clinical medicine, Bisphenol A, biology, respiratory system, MCP-1, monocyte chemoattractant protein-1, RANTES, normal T cell expressed and secreted, Th2 response, medicine.anatomical_structure, MLN, mediastinal lymph node, Endocrine disruptor, Hormone receptor, AhR, aryl hydrocarbon receptor, SDF-1α, stromal cell derived factor 1 alpha, MIP-1α, macrophage inflammatory protein 1-alpha, hormones, hormone substitutes, and hormone antagonists, medicine.medical_specialty, endocrine system, Article, BPA, bisphenol a, 03 medical and health sciences, OVA, ovalbumin, Downregulation and upregulation, lcsh:RA1190-1270, Internal medicine, Low dose effects, medicine, Ar, androgen receptor, FACS, fluorescence-activated cell-sorting, Gr-1, granulocyte-differentiation antigen, Th, T helper, IFN-γ, interferon-gamma, lcsh:Toxicology. Poisons, 0105 earth and related environmental sciences, Lung, GR, glucocorticoid receptor, business.industry, urogenital system, Ig, immunoglobulin, respiratory tract diseases, IL, interleukin, Ovalbumin, Endocrinology, Hprt1, hypoxanthine phosphoribosyltransferase 1, biology.protein, BM, bone marrow, Bone marrow, business, 030217 neurology & neurosurgery
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المؤلفون: Mercedes Lopez-Santalla, Juan A. Bueren, Marina I. Garin
المصدر: EBioMedicine, Vol 69, Iss, Pp 103427-(2021)
EBioMedicineمصطلحات موضوعية: Oncology, ID, intradermal, RANTES, regulated upon activation normal T cells expressed and presumably secreted, AS, arthritis score, RA, rheumatoid arthritis, PPAR, peroxisome proliferator-activated receptor, Etanercept, TNF-α, tumour necrosis factor α, Bzb, bortezomib, iLNs, inguinal lymph nodes, CXCR3, chemokine receptor 3-alternative, BMZ, betamethasone, Medicine, CIA, collagen-induced arthritis, PP, peyer's patch, GIP, gastric inhibitory polypeptide, D, days, EVs, extracellular vesicles, Mtx, methotrexate, mAIA, antigen-induced arthritis in mouse, MTC, Masson´s trichrome, 030220 oncology & carcinogenesis, Rheumatoid arthritis, CTLA4, cytotoxic T lymphocyte antigen, iNOS, inducible nitric oxide synthase, KC, keratinocyte chemo-attractant, OCPs, osteoclast precursors, MCP-1, monocyte chemotactic protein 1, PTPN22, protein tyrosine-phosphatase 22, medicine.medical_specialty, rAIA, adjuvant-induced arthritis in rats, MensMSCs, MSCs from menstrual fluid, BM-MSCs, MSCs from bone marrow, MIP-2, macrophage inflammatory protein 2, 03 medical and health sciences, R5-920, IP10, IFN-γ-induced protein 10, IM, intramuscular, NRP-1, neuropilin-1, S, syngeneic, ESR, erythrocyte sedimentation rate, MPs, microparticles, PBMCs, peripheral blood mononuclear cells, AD, adipose tissue, MVs, microvesicles, P, placenta, sCIA, collagen-induced arthritis in sheep, Bregs, regulatory B cells, X, xenogeneic, Improvements in MSC-based therapy, AD-MSCs, MSCs from adipose tissue, 030104 developmental biology, TF, tissue factor, Protocols, Gilz, glucocorticoid-induced leucine zipper, DM, dexamethasone, STAT3, signal transducer and activator of transcription 3, ANA, Anti-nuclear antibodies, SAA, serum amyloid-A, ERDF, European Regional Development Fund, µCT, micro computed tomography imaging, Arthritis, Rheumatoid, T-AOC, total antioxidant capacity, rCIA, collagen-induced arthritis in rats, ISCT, international society for cellular therapy, NF-κB, nuclear factor-kappa B, RORγT, retinoic acid-related orphan receptor, TCR, T cell receptor, OVAIA, ovalbumin-induced arthritis, UC, umbilical cord, CAIA, collagen-antibody induced arthritis, Flk, tyrosine kinase receptor for vascular endothelial growth factor, IDO, indoleamine 2,3-dioxygenase, MMP, matrix metalloproteinase, Tr1, IL-10-expressing T cells, SM, synovial membrane, medicine.anatomical_structure, IAA, indoleacetic acid, MPCs, mesenchymal precursor cells, SNP, sodium nitroprusside, medicine.drug, NA, not available, IL-1RA, IL-1 receptor antagonist, CD, cluster of differentiation, DMARDs, antirheumatic drugs, TBO, toluidine blue O, =, similar to or equal, SM-MSCs, MSCs from synovial membrane, Mesenchymal Stem Cell Transplantation, PB, peripheral blood, G, gingiva tissue, IFA, incomplete Freund´s adjuvant, OVA, ovalbumin, MSCs, mesenchymal stem/ stromal cells, SO, safranin, TRAF, tumour necrosis factor receptor-associated factor, Animals, SP, spleen, ILA, indole-3-lactic acid, mBSA, methylated bovine serum albumin, business.industry, F, female, SF, synovial fluid, Th, T helper cells, TLR, toll-like receptors, BM, bone marrow, Bone marrow, Synovial membrane, MRI, magnetic resonance imaging, WT, wild type, Medicine (General), IHC, immunohistochemical analysis, Review, miR, microRNA, TRACP, tartrate-resistant acid phosphatase, AAV, adeno-associated virus, 0302 clinical medicine, GSH, glutathione, SVF, stromal vascular fraction, H/E, haematoxylin/eosin staining, GITR, glucocorticoid-induced tumour necrosis factor receptor, pLNs, popliteal lymph nodes, FOXP3, General Medicine, IFI, indirect immunofluorescence, Tregs, regulatory T cells, M, male, RF, rheumatoid factor, RNA, ribonucleic acid, TNFR, tumour necrosis factor receptor, <, worse than, IP, intraperitoneal, NuMa, nuclear mitotic apparatus, COMP, cartilage oligomeric matrix protein, GSH-Px, glutathione peroxidase, >, better than, LP, lamina propria, LPS, lipopolysaccharide, IN, intranodal, AT, antithrombin, General Biochemistry, Genetics and Molecular Biology, CM, conditioned medium, Consec., consecutive, RAGE, receptor for advanced glycation products, ETN, etanercept, Humans, dLNs, draining lymph nodes, MDA, malondialdehyde, IFN-γ, interferon gamma, ALP, alkaline phosphatase, HSCs, hematopoietic stem cells, Mesenchymal stem cell, Mesenchymal Stem Cells, medicine.disease, EMA, European medicine agency, IL, interleukin, CFA, Freund's complete adjuvant, DAB, 3,3´-diaminobenzidine, OPG, osteoprotegerin, HMGB-1, high-mobility group box-1, CRP, C reactive protein, Tol-DCs, tolerogenic dendritic cells, 0301 basic medicine, CII, collagen II, SF-MSCs, MSCs from synovial fluid, MPO, myeloperoxidease, A, allogeneic, LDL, low density lipoprotein, APCP, α, β methylene selective A2A adenosine receptor competitive antagonist (CD73 inhibitor), Translational Research, Biomedical, SSEA, severe spontaneous erosive arthritis, mLNs, mesenteric lymph nodes, PGIA, proteoglycan-induced arthritis, Exos, small vesicles/Exosomes, FOXP3, forkhead box P3, RANKL, receptor activator of nuclear factor κB ligand, TGF-β, transforming growth factor β, Stromal vascular fraction, NSAIDs, non-steroidal anti-inflammatory drugs, VEGF, vascular endothelial growth factor, Animal models, AhR, aryl hydrocarbon receptor, DCs, dendritic cells, IV, intravenous, Stromal cell, IA, intra-articular, SIRT1, sirtuin 1, O-MSCs, MSCs from nasal tissue, PA, peri-articular, Tfh, follicular T helper cells, AxLNs, axillar lymph nodes, NK, natural killer cells, T-MSCs, MSCs from tonsil tissue, SOD, superoxide dismutase, Internal medicine, MHC, major histocompatibility complex, GLP-1, glucagon-like peptide 1, G-MSCs, MSCs from gingiva tissue, Mesenchymal stem/stromal cells, PG, proteoglycan, HLA-II, human leukocyte antigen-II, PLGA, poly-lactic-co-glycolic acid, HDL, high density lipoprotein, Ig, immunoglobulin, SC, subcutaneous, P-MSCs, MSCs from placenta tissue, POM-1, sodium polyoxotungstate (CD39 inhibitor), UC-MSCs, MSCs from umbilical cord, business, sIL6R, soluble IL-6 receptor
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المؤلفون: Jenny P.-Y. Ting, Dale J. Calleja, Phil Hansbro, Katja Hrovat-Schaale, Cassandra R. Harapas, Matthias Geyer, Scott Huntsman, Esteban G. Burchard, Donglei Hu, Chien-Hsiung Yu, Seth L. Masters, Jay C. Horvat, Sophia Davidson, Marquitta J. White, Katelyn Chalker, Pawat Laohamonthonkul, Robert J.J. O'Donoghue, Motti Gerlic, Jonas Moecking, Celeste Eng
المصدر: The Journal of Allergy and Clinical Immunology
مصطلحات موضوعية: 0301 basic medicine, Allergy, Inflammasomes, ASC, Apoptosis-associated speck-like protein containing a CARD, Pathogenesis, Mice, 0302 clinical medicine, Dipeptidyl Peptidase 9, Immunology and Allergy, NLRP, Nucleotide-binding oligomerization domain-like receptor containing a pyrin domain, Mice, Knockout, SNP, Single nucleotide polymorphism, Trauma Severity Indices, OVA, Ovalbumin, NLRP1, GALA II, Genes-Environment & Admixture in Latino Americans II, Inflammasome, DPP9, Dipeptidyl peptidase 9, SAGE II, Study of African Americans, Asthma, Genes, and Environments II, Disease Susceptibility, medicine.drug, BAL, Bronchoalveolar lavage, WT, Wild-type, Immunology, SNP, NLR Proteins, Context (language use), BMI, Body mass index, Asthma and Lower Airway Disease, DPP9, Polymorphism, Single Nucleotide, Cell Line, Structure-Activity Relationship, 03 medical and health sciences, inflammasome, medicine, Animals, Humans, Genetic Predisposition to Disease, Amino Acid Sequence, Dipeptidyl-Peptidases and Tripeptidyl-Peptidases, Alleles, Asthma, Innate immune system, business.industry, asthma, medicine.disease, Eosinophils, Disease Models, Animal, 030104 developmental biology, Amino Acid Substitution, Mutation, business, 030215 immunology
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18
المؤلفون: Toshiaki Yoshikawa, Tatsuaki Iwama, Shigehisa Kitano, Shiori Sugai, Manami Shimomura, Norihiro Fujinami, Yasushi Uemura, Tetsuya Nakatsura, Yu Sawada
المصدر: Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 5, Iss C, Pp 482-491 (2016)مصطلحات موضوعية: 0301 basic medicine, Combination therapy, medicine.medical_treatment, Biophysics, Treg, regulatory T cell, Biochemistry, lcsh:Biochemistry, OVA, ovalbumin, 03 medical and health sciences, DC, dendritic cell, 0302 clinical medicine, MHC, major histocompatibility complex, Medicine, Cytotoxic T cell, lcsh:QD415-436, IFN-γ, interferon-γ, mAb, monoclonal antibody, Anti-CD4 antibody, lcsh:QH301-705.5, FOXP3, forkhead box P3, GPC3, glypican-3, Cancer, Peptide vaccine, TNF, tumor necrosis factor, Murine liver metastatic model, 7-AAD, 7-amino-actinomycin D, IL-2, interleukine-2, business.industry, ELISPOT, ELISPOT assay, enzyme-linked immunospot assay, Immunotherapy, PE, phycoerythrin, CTL, cytotoxic T lymphocyte, Granzyme B, QOL, quality of life, CTL, 030104 developmental biology, lcsh:Biology (General), 030220 oncology & carcinogenesis, Immunology, PD-1, programmed death-1, TGF-β, transforming growth factor-βl, FITC, fluorescein isothiocyanate, Cancer vaccine, HCC, hepatocellular carcinoma, business, Research Article
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19
المؤلفون: Jason R. Devlin, Lance M. Hellman, Jiaqi Ma, Cory M. Ayres, Brian M. Baker
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, binding, VSV, vesicular stomatitis virus, Allosteric regulation, SPR, surface plasmon resonance, Peptide, Molecular Dynamics Simulation, DSF, differential scanning fluorimetry, Major histocompatibility complex, Biochemistry, Substrate Specificity, Turn (biochemistry), thermodynamics, NKD, natural killer domain, OVA, ovalbumin, Mice, 03 medical and health sciences, Allosteric Regulation, Protein Domains, MHC, major histocompatibility complex, Animals, Receptor, Molecular Biology, chemistry.chemical_classification, natural killer cells, 030102 biochemistry & molecular biology, biology, ITC, isothermal titration calorimetry, TCR, T cell receptor, Protein dynamics, T-cell receptor, Isothermal titration calorimetry, Cell Biology, electrostatics, major histocompatibility complex, isothermal titration calorimetry, Killer Cells, Natural, Kinetics, 030104 developmental biology, chemistry, protein dynamics, biology.protein, Biophysics, linkage, NK, natural killer, NK Cell Lectin-Like Receptor Subfamily A, Research Article, Protein Binding
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20
المؤلفون: Stefania Pittaluga, Michail S. Lionakis, Anna Villa, Isabelle Meyts, Andrea Finocchi, Veronica Marrella, Giovanna D'Amico, Silvia Giliani, Rosita Rigoni, Ian A. Myles, Danielle Fink, Douglas B. Kuhns, Kerry Dobbs, Thomas Tousseyn, Simone Guglielmetti, Benedicte Neven, Catharina Schuetz, Amanda Facoetti, Muthulekha Swamydas, Despina Moshous, Virginia Maina, Ghassan Dbaibo, Valentina Taverniti, Elizabeth Garabedian, Alain Fischer, Luigi D. Notarangelo, Deborah Draper, Raif S. Geha, Mario E Cruz-Muñoz, Ansgar Schulz, Barbara Cassani, Andrew R. Gennery, Julie Alejo, Elena Fontana, Waleed Al-Herz
المصدر: The Journal of Allergy and Clinical Immunology
مصطلحات موضوعية: 0301 basic medicine, DLN, Draining lymph node, Chemokine, OS, Omenn syndrome, Lymphocyte, chemokines, OT, OVA transgenic mouse, 0302 clinical medicine, gut-skin axis, CXCL, C-X-C motif chemokine ligand, Immunology and Allergy, CLA, Cutaneous lymphocyte antigen, OVA, Ovalbumin, integumentary system, biology, medicine.diagnostic_test, dysbiosis, Rag2R229Q, 129Sv/C57BL/6 knock-in Rag2R229Q/R229Q, DC, Dendritic cell, FACS, Fluorescence-activated cell sorting, DSS, Dextran sulfate sodium salt, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Actb, Housekeeping gene β-actin, H&E, Hematoxylin and eosin, Interleukin 13, AD, Atopic dermatitis, PLN, Peripheral lymph nodes, cytokines, erythroderma, immune-mediated disease, LPS, RAG, skin inflammation, T cells, Interleukin 17, medicine.symptom, TLR, Toll-like receptor, Immunology, MLN, Mesenteric lymph node, Inflammation, Proinflammatory cytokine, 03 medical and health sciences, CCL, Chemokine C-C motif ligand, medicine, business.industry, Translational and Clinical Immunology, Dendritic cell, EB, Evans blue dye, 030104 developmental biology, Skin biopsy, biology.protein, HD, Healthy donor, business, WT, Wild type
وصف الملف: Print-Electronic